메뉴 건너뛰기




Volumn 1, Issue , 2013, Pages 249-259

Autocrine and Paracrine Actions of IGF-I Signaling in Skeletal Development

Author keywords

Calcium sensing receptor; CaSR; cell cell communication; chondrocyte; GH; IGF I; IGF IR; osteoblast; osteoclast; PTH; signaling

Indexed keywords


EID: 84961737168     PISSN: 20954700     EISSN: 20956231     Source Type: Journal    
DOI: 10.4248/BR201303003     Document Type: Review
Times cited : (61)

References (85)
  • 1
    • 0346206633 scopus 로고
    • A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro
    • Salmon WD Jr, Daughaday WH. A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro. J Lab Clin Med. 1957;49:825-836.
    • (1957) J Lab Clin Med , vol.49 , pp. 825-836
    • Salmon, W.D.1    Daughaday, W.H.2
  • 4
    • 0036999390 scopus 로고    scopus 로고
    • A model for tissue-specific inducible insulin-like growth factor-I (IGF-I) inactivation to determine the physiological role of liver-derived IGF-I
    • Sjogren K, Jansson JO, Isaksson OG, Ohlsson C. A model for tissue-specific inducible insulin-like growth factor-I (IGF-I) inactivation to determine the physiological role of liver-derived IGF-I. Endocrine. 2002;19:249-256.
    • (2002) Endocrine , vol.19 , pp. 249-256
    • Sjogren, K.1    Jansson, J.O.2    Isaksson, O.G.3    Ohlsson, C.4
  • 5
    • 0025320906 scopus 로고
    • A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting
    • DeChiara TM, Efstratiadis A, Robertson EJ. A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature. 1990;345:78-80.
    • (1990) Nature , vol.345 , pp. 78-80
    • DeChiara, T.M.1    Efstratiadis, A.2    Robertson, E.J.3
  • 6
    • 0025967857 scopus 로고
    • Parental imprinting of the mouse insulin-like growth factor II gene
    • DeChiara TM, Robertson EJ, Efstratiadis A. Parental imprinting of the mouse insulin-like growth factor II gene. Cell. 1991;64:849-859.
    • (1991) Cell , vol.64 , pp. 849-859
    • DeChiara, T.M.1    Robertson, E.J.2    Efstratiadis, A.3
  • 7
    • 0027991465 scopus 로고
    • Regional variation of insulin-like growth factor-I gene expression in mature rat bone and cartilage
    • Lazowski DA, Fraher LJ, Hodsman A, Steer B, Modrowski D, Han VK. Regional variation of insulin-like growth factor-I gene expression in mature rat bone and cartilage. Bone. 1994;15:563-576.
    • (1994) Bone , vol.15 , pp. 563-576
    • Lazowski, D.A.1    Fraher, L.J.2    Hodsman, A.3    Steer, B.4    Modrowski, D.5    Han, V.K.6
  • 8
    • 0030992188 scopus 로고    scopus 로고
    • Identification and characterization of the insulin-like growth factor I receptor in mature rabbit osteoclasts
    • Hou P, Sato T, Hofstetter W, Foged NT. Identification and characterization of the insulin-like growth factor I receptor in mature rabbit osteoclasts. J Bone Miner Res. 1997;12:534-540.
    • (1997) J Bone Miner Res , vol.12 , pp. 534-540
    • Hou, P.1    Sato, T.2    Hofstetter, W.3    Foged, N.T.4
  • 9
    • 0028998164 scopus 로고
    • Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis
    • Wang E, Wang J, Chin E, Zhou J, Bondy CA. Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis. Endocrinology. 1995;136:2741-2751.
    • (1995) Endocrinology , vol.136 , pp. 2741-2751
    • Wang, E.1    Wang, J.2    Chin, E.3    Zhou, J.4    Bondy, C.A.5
  • 10
    • 33947377168 scopus 로고    scopus 로고
    • Effect of mechanical loading on insulin-like growth factor-I gene expression in rat tibia
    • Reijnders CM, Bravenboer N, Tromp AM, Blankenstein MA, Lips P. Effect of mechanical loading on insulin-like growth factor-I gene expression in rat tibia. J Endocrinol. 2007;192:131-140.
    • (2007) J Endocrinol , vol.192 , pp. 131-140
    • Reijnders, C.M.1    Bravenboer, N.2    Tromp, A.M.3    Blankenstein, M.A.4    Lips, P.5
  • 11
    • 0020315756 scopus 로고
    • The subunit structures of two distinct receptors for insulin-like growth factors I and II and their relationship to the insulin receptor
    • Massague J, Czech MP. The subunit structures of two distinct receptors for insulin-like growth factors I and II and their relationship to the insulin receptor. J Biol Chem. 1982;257:5038-5045.
    • (1982) J Biol Chem , vol.257 , pp. 5038-5045
    • Massague, J.1    Czech, M.P.2
  • 12
    • 0022800838 scopus 로고
    • Insulin-like growth factor I receptor primary structure: Comparison with insulin receptor suggests structural determinants that define functional specificity
    • Ullrich A, Gray A, Tam AW, Yang-Feng T, Tsubokawa M, Collins C, Henzel W, Le Bon T, Kathuria S, Chen E, et al. Insulin-like growth factor I receptor primary structure: Comparison with insulin receptor suggests structural determinants that define functional specificity. Embo J. 1986;5:2503-2512.
    • (1986) Embo J , vol.5 , pp. 2503-2512
    • Ullrich, A.1    Gray, A.2    Tam, A.W.3    Yang-Feng, T.4    Tsubokawa, M.5    Collins, C.6    Henzel, W.7    Le Bon, T.8    Kathuria, S.9    Chen, E.10
  • 13
    • 0022261491 scopus 로고
    • Characterization of insulin-like growth factor I-stimulated tyrosine kinase activity associated with the beta-subunit of type I insulin-like growth factor receptors of rat liver cells
    • Sasaki N, Rees-Jones RW, Zick Y, Nissley SP, Rechler MM. Characterization of insulin-like growth factor I-stimulated tyrosine kinase activity associated with the beta-subunit of type I insulin-like growth factor receptors of rat liver cells. J Biol Chem. 1985;260:9793-9804.
    • (1985) J Biol Chem , vol.260 , pp. 9793-9804
    • Sasaki, N.1    Rees-Jones, R.W.2    Zick, Y.3    Nissley, S.P.4    Rechler, M.M.5
  • 14
    • 0035185571 scopus 로고    scopus 로고
    • Structure and autoregulation of the insulin-like growth factor 1 receptor kinase
    • Favelyukis S, Till JH, Hubbard SR, Miller WT. Structure and autoregulation of the insulin-like growth factor 1 receptor kinase. Nat Struct Biol. 2001;8:1058-1063.
    • (2001) Nat Struct Biol , vol.8 , pp. 1058-1063
    • Favelyukis, S.1    Till, J.H.2    Hubbard, S.R.3    Miller, W.T.4
  • 16
    • 0027516706 scopus 로고
    • IRS-1 is a common element in insulin and insulin-like growth factor-I signaling to the phosphatidylinositol 3'-kinase
    • Myers MG Jr, Sun XJ, Cheatham B, Jachna BR, Glasheen EM, Backer JM, White MF. IRS-1 is a common element in insulin and insulin-like growth factor-I signaling to the phosphatidylinositol 3'-kinase. Endocrinology. 1993;132:1421-1430.
    • (1993) Endocrinology , vol.132 , pp. 1421-1430
    • Myers, M.G.1    Sun, X.J.2    Cheatham, B.3    Jachna, B.R.4    Glasheen, E.M.5    Backer, J.M.6    White, M.F.7
  • 20
    • 0028957113 scopus 로고
    • Molecular and cellular aspects of the insulin-like growth factor I receptor
    • LeRoith D, Werner H, Beitner-Johnson D, Roberts CT Jr. Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr Rev. 1995;16:143-163.
    • (1995) Endocr Rev , vol.16 , pp. 143-163
    • LeRoith, D.1    Werner, H.2    Beitner-Johnson, D.3    Roberts, C.T.4
  • 21
    • 0034710915 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin
    • Playford MP, Bicknell D, Bodmer WF, Macaulay VM. Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin. Proc Natl Acad Sci USA. 2000;97: 12103-12108.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12103-12108
    • Playford, M.P.1    Bicknell, D.2    Bodmer, W.F.3    MacAulay, V.M.4
  • 22
    • 0036153327 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor by IGF-I in osteoblast-like cells is mediated by the PI3K signaling pathway through the hypoxia-inducible factor-2alpha
    • Akeno N, Robins J, Zhang M, Czyzyk-Krzeska MF, Clemens TL. Induction of vascular endothelial growth factor by IGF-I in osteoblast-like cells is mediated by the PI3K signaling pathway through the hypoxia-inducible factor-2alpha. Endocrinology. 2002;143:420-425.
    • (2002) Endocrinology , vol.143 , pp. 420-425
    • Akeno, N.1    Robins, J.2    Zhang, M.3    Czyzyk-Krzeska, M.F.4    Clemens, T.L.5
  • 23
    • 68949163251 scopus 로고    scopus 로고
    • Regulation of osteogenesis-angiogenesis coupling by HIFs and VEGF
    • Schipani E, Maes C, Carmeliet G, Semenza GL. Regulation of osteogenesis-angiogenesis coupling by HIFs and VEGF. J Bone Miner Res. 2009;24:1347-1353.
    • (2009) J Bone Miner Res , vol.24 , pp. 1347-1353
    • Schipani, E.1    Maes, C.2    Carmeliet, G.3    Semenza, G.L.4
  • 24
    • 0033973655 scopus 로고    scopus 로고
    • All for one and one for all: Condensations and the initiation of skeletal development
    • Hall BK, Miyake T. All for one and one for all: Condensations and the initiation of skeletal development. Bioessays. 2000;22: 138-147.
    • (2000) Bioessays , vol.22 , pp. 138-147
    • Hall, B.K.1    Miyake, T.2
  • 25
    • 0041656403 scopus 로고    scopus 로고
    • Skeletal development: Insights from targeting the mouse genome
    • Horton WA. Skeletal development: Insights from targeting the mouse genome. Lancet. 2003;362:560-569.
    • (2003) Lancet , vol.362 , pp. 560-569
    • Horton, W.A.1
  • 28
    • 0027496895 scopus 로고
    • Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
    • Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A. Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell. 1993;75:59-72.
    • (1993) Cell , vol.75 , pp. 59-72
    • Liu, J.P.1    Baker, J.2    Perkins, A.S.3    Robertson, E.J.4    Efstratiadis, A.5
  • 29
    • 0027423419 scopus 로고
    • Role of insulin-like growth factors in embryonic and postnatal growth
    • Baker J, Liu JP, Robertson EJ, Efstratiadis A. Role of insulin-like growth factors in embryonic and postnatal growth. Cell. 1993;75: 73-82.
    • (1993) Cell , vol.75 , pp. 73-82
    • Baker, J.1    Liu, J.P.2    Robertson, E.J.3    Efstratiadis, A.4
  • 30
    • 0034007328 scopus 로고    scopus 로고
    • Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes
    • Dietrich P, Dragatsis I, Xuan S, Zeitlin S, Efstratiadis A. Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes. Mamm Genome. 2000;11:196-205.
    • (2000) Mamm Genome , vol.11 , pp. 196-205
    • Dietrich, P.1    Dragatsis, I.2    Xuan, S.3    Zeitlin, S.4    Efstratiadis, A.5
  • 31
    • 0023511726 scopus 로고
    • Identification of a phenotype-specific enhancer in the first intron of the rat collagen II gene
    • Horton W, Miyashita T, Kohno K, Hassell JR, Yamada Y. Identification of a phenotype-specific enhancer in the first intron of the rat collagen II gene. Proc Natl Acad Sci USA. 1987;84:8864-8868.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 8864-8868
    • Horton, W.1    Miyashita, T.2    Kohno, K.3    Hassell, J.R.4    Yamada, Y.5
  • 33
    • 16644372994 scopus 로고    scopus 로고
    • Targeted somatic mutagenesis in the mouse epidermis
    • Metzger D, Li M, Chambon P. Targeted somatic mutagenesis in the mouse epidermis. Methods Mol Biol. 2005;289:329-340.
    • (2005) Methods Mol Biol , vol.289 , pp. 329-340
    • Metzger, D.1    Li, M.2    Chambon, P.3
  • 34
    • 33748335730 scopus 로고    scopus 로고
    • Kinetics of tamoxifenregulated Cre activity in mice using a cartilage-specific CreER(T) to assay temporal activity windows along the proximodistal limb skeleton
    • Nakamura E, Nguyen MT, Mackem S. Kinetics of tamoxifenregulated Cre activity in mice using a cartilage-specific CreER(T) to assay temporal activity windows along the proximodistal limb skeleton. Dev Dyn. 2006;235:2603-2612.
    • (2006) Dev Dyn , vol.235 , pp. 2603-2612
    • Nakamura, E.1    Nguyen, M.T.2    MacKem, S.3
  • 35
    • 0029750190 scopus 로고    scopus 로고
    • Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein
    • Vortkamp A, Lee K, Lanske B, Segre GV, Kronenberg HM, Tabin CJ. Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein. Science. 1996;273:613-622.
    • (1996) Science , vol.273 , pp. 613-622
    • Vortkamp, A.1    Lee, K.2    Lanske, B.3    Segre, G.V.4    Kronenberg, H.M.5    Tabin, C.J.6
  • 36
    • 0033950445 scopus 로고    scopus 로고
    • Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone relatedprotein-dependent and-independent pathways
    • Karp SJ, Schipani E, St-Jacques B, Hunzelman J, Kronenberg H, McMahon AP. Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone relatedprotein-dependent and-independent pathways. Development. 2000;127:543-548.
    • (2000) Development , vol.127 , pp. 543-548
    • Karp, S.J.1    Schipani, E.2    St-Jacques, B.3    Hunzelman, J.4    Kronenberg, H.5    McMahon, A.P.6
  • 37
    • 0038687536 scopus 로고    scopus 로고
    • Developmental regulation of the growth plate
    • Kronenberg HM. Developmental regulation of the growth plate. Nature. 2003;423:332-336.
    • (2003) Nature , vol.423 , pp. 332-336
    • Kronenberg, H.M.1
  • 38
    • 0032573058 scopus 로고    scopus 로고
    • The parathyroid hormone/parathyroid hormone-related peptide receptor coordinates endochondral bone development by directly controlling chondrocyte differentiation
    • Chung UI, Lanske B, Lee K, Li E, Kronenberg H. The parathyroid hormone/parathyroid hormone-related peptide receptor coordinates endochondral bone development by directly controlling chondrocyte differentiation. Proc Natl Acad Sci USA. 1998;95: 13030-13035.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13030-13035
    • Chung, U.I.1    Lanske, B.2    Lee, K.3    Li, E.4    Kronenberg, H.5
  • 39
    • 0035135642 scopus 로고    scopus 로고
    • Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development
    • Chung UI, Schipani E, McMahon AP, Kronenberg HM. Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development. J Clin Invest. 2001;107:295-304.
    • (2001) J Clin Invest , vol.107 , pp. 295-304
    • Chung, U.I.1    Schipani, E.2    McMahon, A.P.3    Kronenberg, H.M.4
  • 40
    • 0029811142 scopus 로고    scopus 로고
    • Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation
    • Weir EC, Philbrick WM, Amling M, Neff LA, Baron R, Broadus AE. Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation. Proc Natl Acad Sci USA. 1996;93: 10240-10245.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10240-10245
    • Weir, E.C.1    Philbrick, W.M.2    Amling, M.3    Neff, L.A.4    Baron, R.5    Broadus, A.E.6
  • 41
    • 33748799987 scopus 로고    scopus 로고
    • Independent regulation of skeletal growth by Ihh and IGF signaling
    • Long F, Joeng KS, Xuan S, Efstratiadis A, McMahon AP. Independent regulation of skeletal growth by Ihh and IGF signaling. Dev Biol. 2006;298:327-333.
    • (2006) Dev Biol , vol.298 , pp. 327-333
    • Long, F.1    Joeng, K.S.2    Xuan, S.3    Efstratiadis, A.4    McMahon, A.P.5
  • 42
    • 33746741731 scopus 로고    scopus 로고
    • Resurrection of Vitamin D deficiency and rickets
    • Holick MF. Resurrection of vitamin D deficiency and rickets. J Clin Invest. 2006;116:2062-2072.
    • (2006) J Clin Invest , vol.116 , pp. 2062-2072
    • Holick, M.F.1
  • 43
    • 0141464967 scopus 로고    scopus 로고
    • Calcium-deficiency rickets
    • Thacher TD. Calcium-deficiency rickets. Endocr Dev. 2003;6: 105-125.
    • (2003) Endocr Dev , vol.6 , pp. 105-125
    • Thacher, T.D.1
  • 44
    • 55749104922 scopus 로고    scopus 로고
    • The extracellular calcium-sensing receptor (CaSR) is a critical modulator of skeletal development
    • Chang W, Tu C, Chen TH, Bikle D, Shoback D. The extracellular calcium-sensing receptor (CaSR) is a critical modulator of skeletal development. Sci Signal. 2008;1: Ra1.
    • (2008) Sci Signal , vol.1 , pp. Ra1
    • Chang, W.1    Tu, C.2    Chen, T.H.3    Bikle, D.4    Shoback, D.5
  • 46
    • 0036212302 scopus 로고    scopus 로고
    • Extracellular Ca(2+)-sensing receptors modulate matrix production and mineralization in chondrogenic RCJ3.1C5.18 cells
    • Chang W, Tu C, Pratt S, Chen TH, Shoback D. Extracellular Ca(2+)-sensing receptors modulate matrix production and mineralization in chondrogenic RCJ3.1C5.18 cells. Endocrinology. 2002;143:1467-1474.
    • (2002) Endocrinology , vol.143 , pp. 1467-1474
    • Chang, W.1    Tu, C.2    Pratt, S.3    Chen, T.H.4    Shoback, D.5
  • 47
    • 26844574377 scopus 로고    scopus 로고
    • Extracellular calcium and parathyroid hormone-related peptide signaling modulate the pace of growth plate chondrocyte differentiation
    • Rodriguez L, Cheng Z, Chen TH, Tu C, Chang W. Extracellular calcium and parathyroid hormone-related peptide signaling modulate the pace of growth plate chondrocyte differentiation. Endocrinology. 2005;146:4597-4608.
    • (2005) Endocrinology , vol.146 , pp. 4597-4608
    • Rodriguez, L.1    Cheng, Z.2    Chen, T.H.3    Tu, C.4    Chang, W.5
  • 49
    • 34447132814 scopus 로고    scopus 로고
    • Skeletal remodeling in health and disease
    • Zaidi M. Skeletal remodeling in health and disease. Nat Med. 2007;13:791-801.
    • (2007) Nat Med , vol.13 , pp. 791-801
    • Zaidi, M.1
  • 52
    • 37249048812 scopus 로고    scopus 로고
    • A novel transgenic mouse model to study the osteoblast lineage in vivo
    • Maes C, Kobayashi T, Kronenberg HM. A novel transgenic mouse model to study the osteoblast lineage in vivo. Ann N Y Acad Sci. 2007;1116:149-164.
    • (2007) Ann N y Acad Sci , vol.1116 , pp. 149-164
    • Maes, C.1    Kobayashi, T.2    Kronenberg, H.M.3
  • 53
    • 35848958601 scopus 로고    scopus 로고
    • Integration of signaling pathways regulating chondrocyte differentiation during endochondral bone formation
    • Adams SL, Cohen AJ, Lassova L. Integration of signaling pathways regulating chondrocyte differentiation during endochondral bone formation. J Cell Physiol. 2007;213:635-641.
    • (2007) J Cell Physiol , vol.213 , pp. 635-641
    • Adams, S.L.1    Cohen, A.J.2    Lassova, L.3
  • 54
    • 0023832454 scopus 로고
    • Insulin-like growth factor I has independent effects on bone matrix formation and cell replication
    • Hock JM, Centrella M, Canalis E. Insulin-like growth factor I has independent effects on bone matrix formation and cell replication. Endocrinology. 1988;122:254-260.
    • (1988) Endocrinology , vol.122 , pp. 254-260
    • Hock, J.M.1    Centrella, M.2    Canalis, E.3
  • 55
    • 0030854867 scopus 로고    scopus 로고
    • Multiple extracellular signals promote osteoblast survival and apoptosis
    • Hill PA, Tumber A, Meikle MC. Multiple extracellular signals promote osteoblast survival and apoptosis. Endocrinology. 1997;138:3849-3858.
    • (1997) Endocrinology , vol.138 , pp. 3849-3858
    • Hill, P.A.1    Tumber, A.2    Meikle, M.C.3
  • 56
    • 0034526805 scopus 로고    scopus 로고
    • Autocrine signals promote osteoblast survival in culture
    • Tumber A, Meikle MC, Hill PA. Autocrine signals promote osteoblast survival in culture. J Endocrinol. 2000;167:383-390.
    • (2000) J Endocrinol , vol.167 , pp. 383-390
    • Tumber, A.1    Meikle, M.C.2    Hill, P.A.3
  • 61
    • 77950649084 scopus 로고    scopus 로고
    • Dynamics of the transition from osteoblast to osteocyte
    • Dallas SL, Bonewald LF. Dynamics of the transition from osteoblast to osteocyte. Ann N Y Acad Sci. 2010;1192: 437-443.
    • (2010) Ann N y Acad Sci , vol.1192 , pp. 437-443
    • Dallas, S.L.1    Bonewald, L.F.2
  • 62
    • 79251493453 scopus 로고    scopus 로고
    • The amazing osteocyte
    • Bonewald LF. The amazing osteocyte. J Bone Miner Res. 2011;26: 229-238.
    • (2011) J Bone Miner Res , vol.26 , pp. 229-238
    • Bonewald, L.F.1
  • 63
    • 84867477893 scopus 로고    scopus 로고
    • Disruption of the insulin-like growth factor-1 gene in osteocytes impairs developmental bone growth in mice
    • Sheng MH, Zhou XD, Bonewald LF, Baylink DJ, Lau KH. Disruption of the insulin-like growth factor-1 gene in osteocytes impairs developmental bone growth in mice. Bone. 2013;52: 133-144.
    • (2013) Bone , vol.52 , pp. 133-144
    • Sheng, M.H.1    Zhou, X.D.2    Bonewald, L.F.3    Baylink, D.J.4    Lau, K.H.5
  • 66
    • 0043267732 scopus 로고    scopus 로고
    • Genetic regulation of osteoclast development and function
    • Teitelbaum SL, Ross FP. Genetic regulation of osteoclast development and function. Nat Rev Genet. 2003;4:638-649.
    • (2003) Nat Rev Genet , vol.4 , pp. 638-649
    • Teitelbaum, S.L.1    Ross, F.P.2
  • 68
    • 78649544062 scopus 로고    scopus 로고
    • IGF-1 and bone: New discoveries from mouse models
    • Yakar S, Courtland HW, Clemmons D. IGF-1 and bone: New discoveries from mouse models. J Bone Miner Res. 2010;25:2543-2552.
    • (2010) J Bone Miner Res , vol.25 , pp. 2543-2552
    • Yakar, S.1    Courtland, H.W.2    Clemmons, D.3
  • 69
    • 0023918276 scopus 로고
    • The ontogeny of growth hormone receptors in the rabbit tibia
    • Barnard R, Haynes KM, Werther GA, Waters MJ. The ontogeny of growth hormone receptors in the rabbit tibia. Endocrinology. 1988;122:2562-2569.
    • (1988) Endocrinology , vol.122 , pp. 2562-2569
    • Barnard, R.1    Haynes, K.M.2    Werther, G.A.3    Waters, M.J.4
  • 75
    • 0032894565 scopus 로고    scopus 로고
    • Skeletal unloading causes resistance of osteoprogenitor cells to parathyroid hormone and to insulin-like growth factor-I
    • Kostenuik PJ, Harris J, Halloran BP, Turner RT, Morey-Holton ER, Bikle DD. Skeletal unloading causes resistance of osteoprogenitor cells to parathyroid hormone and to insulin-like growth factor-I. J Bone Miner Res. 1999;14:21-31.
    • (1999) J Bone Miner Res , vol.14 , pp. 21-31
    • Kostenuik, P.J.1    Harris, J.2    Halloran, B.P.3    Turner, R.T.4    Morey-Holton, E.R.5    Bikle, D.D.6
  • 78
    • 0033305046 scopus 로고    scopus 로고
    • Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: Correlation with osteoclastlike cell formation
    • Lee SK, Lorenzo JA. Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: Correlation with osteoclastlike cell formation. Endocrinology. 1999;140:3552-3561.
    • (1999) Endocrinology , vol.140 , pp. 3552-3561
    • Lee, S.K.1    Lorenzo, J.A.2
  • 79
    • 0034878897 scopus 로고    scopus 로고
    • Catabolic effects of continuous human PTH (1-38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation
    • Ma YL, Cain RL, Halladay DL, Yang X, Zeng Q, Miles RR, Chandrasekhar S, Martin TJ, Onyia JE. Catabolic effects of continuous human PTH (1-38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation. Endocrinology. 2001;142:4047-4054.
    • (2001) Endocrinology , vol.142 , pp. 4047-4054
    • Ma, Y.L.1    Cain, R.L.2    Halladay, D.L.3    Yang, X.4    Zeng, Q.5    Miles, R.R.6    Chandrasekhar, S.7    Martin, T.J.8    Onyia, J.E.9
  • 80
    • 0024532580 scopus 로고
    • Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures
    • Canalis E, Centrella M, Burch W, McCarthy TL. Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures. J Clin Invest. 1989;83:60-65.
    • (1989) J Clin Invest , vol.83 , pp. 60-65
    • Canalis, E.1    Centrella, M.2    Burch, W.3    McCarthy, T.L.4
  • 81
    • 0030962888 scopus 로고    scopus 로고
    • Parathyroid hormone exerts disparate effects on osteoblast differentiation depending on exposure time in rat osteoblastic cells
    • Ishizuya T, Yokose S, Hori M, Noda T, Suda T, Yoshiki S, Yamaguchi A. Parathyroid hormone exerts disparate effects on osteoblast differentiation depending on exposure time in rat osteoblastic cells. J Clin Invest. 1997;99:2961-2970.
    • (1997) J Clin Invest , vol.99 , pp. 2961-2970
    • Ishizuya, T.1    Yokose, S.2    Hori, M.3    Noda, T.4    Suda, T.5    Yoshiki, S.6    Yamaguchi, A.7
  • 82
    • 84861733148 scopus 로고    scopus 로고
    • Insulin like growth factor-I: A critical mediator of the skeletal response to parathyroid hormone
    • Bikle DD, Wang Y. Insulin like growth factor-I: A critical mediator of the skeletal response to parathyroid hormone. Curr Mol Pharmacol. 2012;5:135-142.
    • (2012) Curr Mol Pharmacol , vol.5 , pp. 135-142
    • Bikle, D.D.1    Wang, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.