메뉴 건너뛰기




Volumn 68, Issue 24, 2008, Pages 10040-10044

Negative regulation of AKT activation by BRCA1

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHRL1;

EID: 57749115897     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-3009     Document Type: Article
Times cited : (106)

References (20)
  • 1
    • 27644543144 scopus 로고    scopus 로고
    • The role of the BRCA1 tumor suppressor in DNA double-strand break repair
    • Zhang J, Powell SN. The role of the BRCA1 tumor suppressor in DNA double-strand break repair. Mol Cancer Res 2005;3:531-9.
    • (2005) Mol Cancer Res , vol.3 , pp. 531-539
    • Zhang, J.1    Powell, S.N.2
  • 2
    • 4544374528 scopus 로고    scopus 로고
    • BRCA1 and BRCA2: 1994 and beyond
    • Narod SA, Foulkes WD. BRCA1 and BRCA2: 1994 and beyond. Nat Rev Cancer 2004;4:665-76.
    • (2004) Nat Rev Cancer , vol.4 , pp. 665-676
    • Narod, S.A.1    Foulkes, W.D.2
  • 3
    • 4344665689 scopus 로고    scopus 로고
    • The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancer
    • McCoy ML, Mueller CR, Roskelley CD. The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancer. Reprod Biol Endocrinol 2003;1:72.
    • (2003) Reprod Biol Endocrinol , vol.1 , pp. 72
    • McCoy, M.L.1    Mueller, C.R.2    Roskelley, C.D.3
  • 4
    • 0142147272 scopus 로고    scopus 로고
    • The BRCT domain is a phospho-protein binding domain
    • Yu X, Chini CC, He M, Mer G, Chen J. The BRCT domain is a phospho-protein binding domain. Science 2003;302:639-42.
    • (2003) Science , vol.302 , pp. 639-642
    • Yu, X.1    Chini, C.C.2    He, M.3    Mer, G.4    Chen, J.5
  • 5
    • 0035872860 scopus 로고    scopus 로고
    • Tumorigenesis in mice carrying a truncating Brca1 mutation
    • Ludwig T, Fisher P, Ganesan S, Efstratiadis A. Tumorigenesis in mice carrying a truncating Brca1 mutation. Genes Dev 2001;15:1188-93.
    • (2001) Genes Dev , vol.15 , pp. 1188-1193
    • Ludwig, T.1    Fisher, P.2    Ganesan, S.3    Efstratiadis, A.4
  • 6
    • 0142240342 scopus 로고    scopus 로고
    • BRCT repeats as phosphopeptide-binding modules involved in protein targeting
    • Manke IA, Lowery DM, Nguyen A, Yaffe MB. BRCT repeats as phosphopeptide-binding modules involved in protein targeting. Science 2003;302:636-9.
    • (2003) Science , vol.302 , pp. 636-639
    • Manke, I.A.1    Lowery, D.M.2    Nguyen, A.3    Yaffe, M.B.4
  • 7
    • 23944526062 scopus 로고    scopus 로고
    • Activation of AKT kinases in cancer: Implications for therapeutic targeting
    • Bellacosa A, Kumar CC, Di CA, Testa JR. Activation of AKT kinases in cancer: implications for therapeutic targeting. Adv Cancer Res 2005;94:29-86.
    • (2005) Adv Cancer Res , vol.94 , pp. 29-86
    • Bellacosa, A.1    Kumar, C.C.2    Di, C.A.3    Testa, J.R.4
  • 8
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley LC. The phosphoinositide 3-kinase pathway. Science 2002;296:1655-7.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 9
    • 24944480788 scopus 로고    scopus 로고
    • The Akt-mTOR tango and its relevance to cancer
    • Hay N. The Akt-mTOR tango and its relevance to cancer. Cancer Cell 2005;8:179-83.
    • (2005) Cancer Cell , vol.8 , pp. 179-183
    • Hay, N.1
  • 10
    • 15944406764 scopus 로고    scopus 로고
    • PHLPP: A phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth
    • Gao T, Furnari F, Newton AC. PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth. Mol Cell 2005;18:13-24.
    • (2005) Mol Cell , vol.18 , pp. 13-24
    • Gao, T.1    Furnari, F.2    Newton, A.C.3
  • 12
    • 0037218809 scopus 로고    scopus 로고
    • Extracellular matrix enhances heregulin-dependent BRCA1 phosphorylation and suppresses BRCA1 expression through its C terminus
    • Miralem T, Avraham HK. Extracellular matrix enhances heregulin-dependent BRCA1 phosphorylation and suppresses BRCA1 expression through its C terminus. Mol Cell Biol 2003;23:579-93.
    • (2003) Mol Cell Biol , vol.23 , pp. 579-593
    • Miralem, T.1    Avraham, H.K.2
  • 14
    • 34547425975 scopus 로고    scopus 로고
    • Growth factor signaling pathways modulate BRCA1 repression of estrogen receptor-α activity
    • Ma Y, Hu C, Riegel AT, Fan S, Rosen EM. Growth factor signaling pathways modulate BRCA1 repression of estrogen receptor-α activity. Mol Endocrinol 2007;21:1905-23.
    • (2007) Mol Endocrinol , vol.21 , pp. 1905-1923
    • Ma, Y.1    Hu, C.2    Riegel, A.T.3    Fan, S.4    Rosen, E.M.5
  • 15
    • 33644684041 scopus 로고    scopus 로고
    • Substrates of the BRCA1-Dependent Ubiquitin Ligase
    • Starita LM, Parvin JD. Substrates of the BRCA1-Dependent Ubiquitin Ligase. Cancer Biol Ther 2006;5:137-41.
    • (2006) Cancer Biol Ther , vol.5 , pp. 137-141
    • Starita, L.M.1    Parvin, J.D.2
  • 16
    • 0036467574 scopus 로고    scopus 로고
    • The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity
    • Baer R, Ludwig T. The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity. Curr Opin Genet Dev 2002;12:86-91.
    • (2002) Curr Opin Genet Dev , vol.12 , pp. 86-91
    • Baer, R.1    Ludwig, T.2
  • 18
    • 0347320584 scopus 로고    scopus 로고
    • Cytoplasmic mislocalization of BRCA1 caused by cancer-associated mutations in the BRCT domain
    • Rodriguez JA, Au WW, Henderson BR. Cytoplasmic mislocalization of BRCA1 caused by cancer-associated mutations in the BRCT domain. Exp Cell Res 2004;293:14-21.
    • (2004) Exp Cell Res , vol.293 , pp. 14-21
    • Rodriguez, J.A.1    Au, W.W.2    Henderson, B.R.3
  • 20
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
    • Brunet A, Bonni A, Zigmond MJ, et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 1999;96:857-68.
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1    Bonni, A.2    Zigmond, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.