The mitochondrial calcium uniporter regulates breast cancer progression via HIF-1α

EMBO Molecular Medicine

Volumn 8, Issue 5, 2016, Pages 569-585

  Tosatto, Anna ^a   Sommaggio, Roberta ^a   Kummerow, Carsten ^b   Bentham, Robert B ^c   Blacker, Thomas S ^c   Berecz, Tunde ^c   Duchen, Michael R ^c   Rosato, Antonio ^a,d   Bogeski, Ivan ^b   Szabadkai, Gyorgy ^a,c   Rizzuto, Rosario ^a,e   Mammucari, Cristina ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

^e CNR   (Italy)

Author keywords

Breast cancer; HIF 1 ; Metastasis; Mitochondrial Ca2+ uptake; Reactive oxygen species

Indexed keywords

CALCIUM CHANNEL; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MITOCHONDRIAL CALCIUM UNIPORTER; MITOCHONDRIAL REACTIVE OXYGEN SPECIES; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; HIF1A PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CANCER GROWTH; CELL INVASION; CELL MOTILITY; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG METASTASIS; LYMPH NODE METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRIPLE NEGATIVE BREAST CANCER; TUMOR GROWTH; ANIMAL; CELL MOTION; CELL PROLIFERATION; GENE SILENCING; METABOLISM; METASTASIS; PATHOLOGY; SCID MOUSE; TUMOR CELL LINE; TUMOR INVASION; XENOGRAFT;

ANIMALS; CALCIUM CHANNELS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; GENE SILENCING; HETEROGRAFTS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE, SCID; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; REACTIVE OXYGEN SPECIES; TRIPLE NEGATIVE BREAST NEOPLASMS;

EID: 84963644294     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201606255     Document Type: Article

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