Sequential Activation of Two Pathogen-Sensing Pathways Required for Type I Interferon Expression and Resistance to an Acute DNA Virus Infection

Immunity

Volumn 43, Issue 6, 2015, Pages 1148-1159

  Xu, Ren Huan ^a,e   Wong, Eric B ^a,f   Rubio, Daniel ^a,g   Roscoe, Felicia ^a   Ma, Xueying ^a   Nair, Savita ^a   Remakus, Sanda ^a   Schwendener, Reto ^b   John, Shinu ^c   Shlomchik, Mark ^d   Sigal, Luis J ^a,f  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e NOVAVAX INC   (United States)

^f THOMAS JEFFERSON UNIVERSITY   (United States)

^g GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CHEMOKINE RECEPTOR CCR2; GLYCOPROTEIN P 15095; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERFERON REGULATORY FACTOR 7; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 9; IRF7 PROTEIN, MOUSE; MEMBRANE PROTEIN; MPYS PROTEIN, MOUSE; MYD88 PROTEIN, MOUSE; TLR9 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; INFECTION RESISTANCE; LYMPH NODE; MONOCYTE; MOUSE; MOUSEPOX; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; BIOSYNTHESIS; DNA VIRUS INFECTION; ECTROMELIA VIRUS; FLOW CYTOMETRY; IMMUNOLOGY; KNOCKOUT MOUSE; MUTANT MOUSE STRAIN; SIGNAL TRANSDUCTION;

ANIMALS; DNA VIRUS INFECTIONS; ECTROMELIA VIRUS; ECTROMELIA, INFECTIOUS; FLOW CYTOMETRY; INTERFERON REGULATORY FACTOR-7; INTERFERON TYPE I; LYMPH NODES; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MONOCYTES; MYELOID DIFFERENTIATION FACTOR 88; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 9;

EID: 84963623627     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2015.11.015     Document Type: Article

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