Crosstalk between the type 1 interferon and nuclear factor kappa B pathways confers resistance to a lethal virus infection

Cell Host and Microbe

Volumn 13, Issue 6, 2013, Pages 701-710

  Rubio, Daniel ^a,b   Xu, Ren Huan ^a   Remakus, Sanda ^a   Krouse, Tracy E ^c   Truckenmiller, Mary Ellen ^c   Thapa, Roshan J ^a   Balachandran, Siddharth ^a   Alcamí, Antonio ^b   Norbury, Christopher C ^c   Sigal, Luis J ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERFERON REGULATORY FACTOR 7; PROTEIN P105; PROTEIN P50;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ECTROMELIA VIRUS; HOST RESISTANCE; IMMUNOPATHOGENESIS; IN VIVO STUDY; INNATE IMMUNITY; MOLECULAR INTERACTION; MOUSE; MOUSEPOX; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; VIRUS MUTANT; VIRUS REPLICATION; VIRUS RESISTANCE;

ECTROMELIA VIRUS; ORTHOPOXVIRUS; POXVIRIDAE; VARIOLA VIRUS;

EID: 84879103490     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2013.04.015     Document Type: Article

References (49)

1. O. Adachi, T. Kawai, K. Takeda, M. Matsumoto, H. Tsutsui, M. Sakagami, K. Nakanishi, and S. Akira Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function Immunity 9 1998 143 150
2. S. Balachandran, and A.A. Beg Defining emerging roles for NF-κB in antivirus responses: revisiting the interferon-β enhanceosome paradigm PLoS Pathog. 7 2011 e1002165
3. B. Barnes, B. Lubyova, and P.M. Pitha On the role of IRF in host defense J. Interferon Cytokine Res. 22 2002 59 71
4. S.H. Basagoudanavar, R.J. Thapa, S. Nogusa, J. Wang, A.A. Beg, and S. Balachandran Distinct roles for the NF-kappa B RelA subunit during antiviral innate immune responses J. Virol. 85 2011 2599 2610
5. C. Bogdan The function of type I interferons in antimicrobial immunity Curr. Opin. Immunol. 12 2000 419 424
6. A.G. Bowie, and L. Unterholzner Viral evasion and subversion of pattern-recognition receptor signalling Nat. Rev. Immunol. 8 2008 911 922
7. K. Brennan, and A.G. Bowie Activation of host pattern recognition receptors by viruses Curr. Opin. Microbiol. 13 2010 503 507
8. J. Chang, L.J. Sigal, A. Lerro, and J. Taylor Replication of the human hepatitis delta virus genome Is initiated in mouse hepatocytes following intravenous injection of naked DNA or RNA sequences J. Virol. 75 2001 3469 3473
9. K.C. Chin, and P. Cresswell Viperin (cig5), an IFN-inducible antiviral protein directly induced by human cytomegalovirus Proc. Natl. Acad. Sci. USA 98 2001 15125 15130
10. E. Dixit, S. Boulant, Y. Zhang, A.S. Lee, C. Odendall, B. Shum, N. Hacohen, Z.J. Chen, S.P. Whelan, and M. Fransen Peroxisomes are signaling platforms for antiviral innate immunity Cell 141 2010 668 681
11. D.J. Esteban, and R.M. Buller Ectromelia virus: the causative agent of mousepox J. Gen. Virol. 86 2005 2645 2659
12. F.G. Falkner, and B. Moss Escherichia coli gpt gene provides dominant selection for vaccinia virus open reading frame expression vectors J. Virol. 62 1988 1849 1854
13. M. Fang, L.L. Lanier, and L.J. Sigal A role for NKG2D in NK cell-mediated resistance to poxvirus disease PLoS Pathog. 4 2008 e30
14. M. Fang, F. Roscoe, and L.J. Sigal Age-dependent susceptibility to a viral disease due to decreased natural killer cell numbers and trafficking J. Exp. Med. 207 2010 2369 2381
15. M. Fang, M.T. Orr, P. Spee, T. Egebjerg, L.L. Lanier, and L.J. Sigal CD94 is essential for NK cell-mediated resistance to a lethal viral disease Immunity 34 2011 579 589
16. F. Fenner Mouse-pox; infectious ectromelia of mice; a review J. Immunol. 63 1949 341 373
17. V. Fensterl, and G.C. Sen The ISG56/IFIT1 gene family J. Interferon Cytokine Res. 31 2011 71 78
18. K.A. Fitzgerald, S.M. McWhirter, K.L. Faia, D.C. Rowe, E. Latz, D.T. Golenbock, A.J. Coyle, S.M. Liao, and T. Maniatis IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway Nat. Immunol. 4 2003 491 496
19. S. Gerondakis, R. Grumont, R. Gugasyan, L. Wong, I. Isomura, W. Ho, and A. Banerjee Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models Oncogene 25 2006 6781 6799
20. S. Gross, and D. Piwnica-Worms Real-time imaging of ligand-induced IKK activation in intact cells and in living mice Nat. Methods 2 2005 607 614
21. M. Hasan, J. Koch, D. Rakheja, A.K. Pattnaik, J. Brugarolas, I. Dozmorov, B. Levine, E.K. Wakeland, M.A. Lee-Kirsch, and N. Yan Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes Nat. Immunol. 14 2013 61 71
22. H. Hemmi, O. Takeuchi, T. Kawai, T. Kaisho, S. Sato, H. Sanjo, M. Matsumoto, K. Hoshino, H. Wagner, K. Takeda, and S. Akira A Toll-like receptor recognizes bacterial DNA Nature 408 2000 740 745
23. K. Honda, H. Yanai, H. Negishi, M. Asagiri, M. Sato, T. Mizutani, N. Shimada, Y. Ohba, A. Takaoka, N. Yoshida, and T. Taniguchi IRF-7 is the master regulator of type-I interferon-dependent immune responses Nature 434 2005 772 777
24. Z.G. Liu Molecular mechanism of TNF signaling and beyond Cell Res. 15 2005 24 27
25. F. Liu, Y. Song, and D. Liu Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA Gene Ther. 6 1999 1258 1266
26. J.C. Lo, S. Basak, E.S. James, R.S. Quiambo, M.C. Kinsella, M.L. Alegre, F. Weih, G. Franzoso, A. Hoffmann, and Y.X. Fu Coordination between NF-kappaB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues Blood 107 2006 1048 1055
27. R. Lu, W.C. Au, W.S. Yeow, N. Hageman, and P.M. Pitha Regulation of the promoter activity of interferon regulatory factor-7 gene. Activation by interferon snd silencing by hypermethylation J. Biol. Chem. 275 2000 31805 31812
28. R. Lu, P.A. Moore, and P.M. Pitha Stimulation of IRF-7 gene expression by tumor necrosis factor alpha: requirement for NFkappa B transcription factor and gene accessibility J. Biol. Chem. 277 2002 16592 16598
29. M.R. Mohamed, and G. McFadden NFkB inhibitors: strategies from poxviruses Cell Cycle 8 2009 3125 3132
30. M.R. Mohamed, M.M. Rahman, J.S. Lanchbury, D. Shattuck, C. Neff, M. Dufford, N. van Buuren, K. Fagan, M. Barry, and S. Smith Proteomic screening of variola virus reveals a unique NF-kappaB inhibitor that is highly conserved among pathogenic orthopoxviruses Proc. Natl. Acad. Sci. USA 106 2009 9045 9050
31. M.R. Mohamed, M.M. Rahman, A. Rice, R.W. Moyer, S.J. Werden, and G. McFadden Cowpox virus expresses a novel ankyrin repeat NF-kappaB inhibitor that controls inflammatory cell influx into virus-infected tissues and is critical for virus pathogenesis J. Virol. 83 2009 9223 9236
32. U. Müller, U. Steinhoff, L.F. Reis, S. Hemmi, J. Pavlovic, R.M. Zinkernagel, and M. Aguet Functional role of type I and type II interferons in antiviral defense Science 264 1994 1918 1921
33. S.M. O'Donnell, M.W. Hansberger, J.L. Connolly, J.D. Chappell, M.J. Watson, J.M. Pierce, J.D. Wetzel, W. Han, E.S. Barton, and J.C. Forrest Organ-specific roles for transcription factor NF-kappaB in reovirus-induced apoptosis and disease J. Clin. Invest. 115 2005 2341 2350
34. L.A. O'Neill How Toll-like receptors signal: what we know and what we don't know Curr. Opin. Immunol. 18 2006 3 9
35. A. Okumura, P.M. Pitha, and R.N. Harty ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity Proc. Natl. Acad. Sci. USA 105 2008 3974 3979
36. V. Panchanathan, G. Chaudhri, and G. Karupiah Interferon function is not required for recovery from a secondary poxvirus infection Proc. Natl. Acad. Sci. USA 102 2005 12921 12926
37. C. Samuelsson, J. Hausmann, H. Lauterbach, M. Schmidt, S. Akira, H. Wagner, P. Chaplin, M. Suter, M. O'Keeffe, and H. Hochrein Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection J. Clin. Invest. 118 2008 1776 1784
38. M. Sato, N. Hata, M. Asagiri, T. Nakaya, T. Taniguchi, and N. Tanaka Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7 FEBS Lett. 441 1998 106 110
39. B.T. Seet, J.B. Johnston, C.R. Brunetti, J.W. Barrett, H. Everett, C. Cameron, J. Sypula, S.H. Nazarian, A. Lucas, and G. McFadden Poxviruses and immune evasion Annu. Rev. Immunol. 21 2003 377 423
40. W.C. Sha, H.C. Liou, E.I. Tuomanen, and D. Baltimore Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses Cell 80 1995 321 330
41. S. Sharma, B.R. tenOever, N. Grandvaux, G.P. Zhou, R. Lin, and J. Hiscott Triggering the interferon antiviral response through an IKK-related pathway Science 300 2003 1148 1151
42. V.P. Smith, and A. Alcami Inhibition of interferons by ectromelia virus J. Virol. 76 2002 1124 1134
43. D.B. Sutherland, C. Ranasinghe, M. Regner, S. Phipps, K.I. Matthaei, S.L. Day, and I.A. Ramshaw Evaluating vaccinia virus cytokine co-expression in TLR GKO mice Immunol. Cell Biol. 89 2011 706 715
44. G.D. Wallace, and R.M. Buller Kinetics of ectromelia virus (mousepox) transmission and clinical response in C57BL/6j, BALB/cByj and AKR/J inbred mice Lab. Anim. Sci. 35 1985 41 46
45. X. Wang, S. Hussain, E.J. Wang, X. Wang, M.O. Li, A. García- Sastre, and A.A. Beg Lack of essential role of NF-kappa B p50, RelA, and cRel subunits in virus-induced type 1 IFN expression J. Immunol. 178 2007 6770 6776
46. J. Wang, S.H. Basagoudanavar, X. Wang, E. Hopewell, R. Albrecht, A. García-Sastre, S. Balachandran, and A.A. Beg NF-kappa B RelA subunit is crucial for early IFN-beta expression and resistance to RNA virus replication J. Immunol. 185 2010 1720 1729
47. F. Weih, and J. Caamaño Regulation of secondary lymphoid organ development by the nuclear factor-kappaB signal transduction pathway Immunol. Rev. 195 2003 91 105
48. R.H. Xu, M. Cohen, Y. Tang, E. Lazear, J.C. Whitbeck, R.J. Eisenberg, G.H. Cohen, and L.J. Sigal The orthopoxvirus type I IFN binding protein is essential for virulence and an effective target for vaccination J. Exp. Med. 205 2008 981 992
49. R.H. Xu, D. Rubio, F. Roscoe, T.E. Krouse, M.E. Truckenmiller, C.C. Norbury, P.N. Hudson, I.K. Damon, A. Alcamí, and L.J. Sigal Antibody inhibition of a viral type 1 interferon decoy receptor cures a viral disease by restoring interferon signaling in the liver PLoS Pathog. 8 2012 e1002475