Glutamate carboxypeptidase II gene knockout attenuates oxidative stress and cortical apoptosis after traumatic brain injury

BMC Neuroscience

Volumn 17, Issue 1, 2016, Pages

  Cao, Yang ^a   Gao, Yang ^a   Xu, Siyi ^a   Bao, Jingang ^a   Lin, Yingying ^a   Luo, Xingguang ^b   Wang, Yong ^a   Luo, Qizhong ^a   Jiang, Jiyao ^a   Neale, Joseph H ^c   Zhong, Chunlong ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c GEORGETOWN UNIVERSITY   (United States)

Author keywords

Apoptosis; Gene knockout; Glutamate carboxypeptidase II; NAAG; Oxidative stress; Traumatic brain injury

Indexed keywords

CASPASE 3; CYTOCHROME C; GLUTAMATE CARBOXYPEPTIDASE II; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; BAX PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GCPII GENE; GENE INACTIVATION; HOMEOSTASIS; MALE; MITOCHONDRIAL MEMBRANE; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; TRAUMATIC BRAIN INJURY; UPREGULATION; ANIMAL; BRAIN CORTEX; BRAIN INJURY; GENETICS; KNOCKOUT MOUSE; METABOLISM; MITOCHONDRION; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BRAIN INJURIES; CASPASE 3; CEREBRAL CORTEX; GLUTAMATE CARBOXYPEPTIDASE II; MALE; MICE; MICE, KNOCKOUT; MITOCHONDRIA; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84963558348     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/s12868-016-0251-1     Document Type: Article

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