Reduced glutathione biosynthesis in Drosophila melanogaster causes neuronal defects linked to copper deficiency

Journal of Neurochemistry

Volumn 137, Issue 3, 2016, Pages 360-370

  Mercer, Stephen W ^a   La Fontaine, Sharon ^b,c   Warr, Coral G ^a   Burke, Richard ^a  

^a MONASH UNIVERSITY   (Australia)

^b DEAKIN UNIVERSITY   (Australia)

^c FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

Author keywords

ATP7; copper; CTR1; Drosophila; glutamate cysteine ligase; glutathione

Indexed keywords

COPPER; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; MENKES PROTEIN; ATP7 PROTEIN, DROSOPHILA; CALCITONIN; CATION TRANSPORT PROTEIN; CTR1A PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; KATACALCIN; NEUROPEPTIDE; PEPTIDE FRAGMENT;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATP7A GENE; CATALYSIS; CONTROLLED STUDY; COPPER DEFICIENCY; CTR1A GENE; DIET SUPPLEMENTATION; DISEASE ASSOCIATION; DROSOPHILA MELANOGASTER; GCLC GENE; GENE; GENE OVEREXPRESSION; GENE SILENCING; GENETIC CODE; GENETIC MANIPULATION; GLUTATHIONE METABOLISM; IN VIVO STUDY; LETHALITY; MALE; NERVE CELL LESION; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROGENY; RNA INTERFERENCE; ANIMAL; AXON; BIOSYNTHESIS; CONGENITAL MALFORMATION; DEFICIENCY; DIET; FEMALE; GENETICS; LARVA; METABOLISM; NERVE CELL; PATHOLOGY; ULTRASTRUCTURE; WING;

ANIMALS; AXONS; CALCITONIN; CATION TRANSPORT PROTEINS; COPPER; DIET; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENE KNOCKDOWN TECHNIQUES; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; LARVA; NEURONS; NEUROPEPTIDES; PEPTIDE FRAGMENTS; RNA INTERFERENCE; WINGS, ANIMAL;

EID: 84963537952     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13567     Document Type: Article

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