Overexpression of glutamate-cysteine ligase extends life span in Drosophila melanogaster

Journal of Biological Chemistry

Volumn 280, Issue 45, 2005, Pages 37331-37338

  Orr, William C ^a   Radyuk, Svetlana N ^a   Prabhudesai, Leena ^a   Toroser, Dikran ^b   Benes, Judith J ^a   Luchak, James M ^a   Mockett, Robin J ^b   Rebrin, Igor ^b   Hubbard, J Gregory ^a   Sohal, Rajindar S ^b  

^a SOUTHERN METHODIST UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CATALYSIS; NEUROLOGY; OXIDATION; OXYGEN; TISSUE;

DROSOPHILA MELANOGASTER; GLUTATHIONE; LIGASE; RATE-LIMITING REACTION;

ENZYMES;

GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE;

AGING; ANIMAL CELL; ARTICLE; BIOSYNTHESIS; CATALYSIS; CONTROLLED STUDY; DROSOPHILA; DROSOPHILA MELANOGASTER; EMBRYO; ENZYME ACTIVITY; GENE OVEREXPRESSION; HYPOTHESIS; LIFESPAN; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; TRANSGENE;

ANIMALS; DROSOPHILA MELANOGASTER; GENE EXPRESSION; GLUTAMATE-CYSTEINE LIGASE; HYDROGEN PEROXIDE; LONGEVITY; NEURONS; ORGANISMS, GENETICALLY MODIFIED; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PARAQUAT; PROTEIN SUBUNITS;

ANIMALIA; DROSOPHILA MELANOGASTER;

EID: 27844474722     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M508272200     Document Type: Article

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