γ 3-Glutamylcysteine detoxifies reactive oxygen species by acting as glutathione peroxidase-1 cofactor

Nature Communications

Volumn 3, Issue , 2012, Pages

  Quintana Cabrera, Ruben ^a   Fernandez Fernandez, Seila ^a   Bobo Jimenez, Veronica ^a,b   Escobar, Javier ^c,d   Sastre, Juan ^d   Almeida, Angeles ^a,b   Bolaños, Juan P ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

^b HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

^c HOSPITAL UNIVERSITARIO LA FE   (Spain)

^d UNIVERSITY OF VALENCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; GAMMA GLUTAMYLCYSTEINE; GLUTATHIONE PEROXIDASE 1; HYDROGEN PEROXIDE; NEUROPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; DIPEPTIDE; GAMMA-GLUTAMYLCYSTEINE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BIOSYNTHESIS; CONCENTRATION (PARAMETERS); HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRION; MOTOR DYSFUNCTION; MOUSE; NERVE CELL; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; ANIMAL; CELL LINE; CELL STRAIN 3T3; CELL STRAIN HEK293; COENZYME; DRUG DETOXIFICATION; GENETICS; METABOLISM; OXIDATIVE STRESS; PHYSIOLOGY; RAT; RNA INTERFERENCE; WISTAR RAT;

3T3 CELLS; ANIMALS; APOPTOSIS; CELL LINE; COENZYMES; DIPEPTIDES; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HEK293 CELLS; HUMANS; HYDROGEN PEROXIDE; METABOLIC DETOXICATION, DRUG; MICE; MITOCHONDRIA; NEURONS; OXIDATIVE STRESS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SUPEROXIDES;

EID: 84859201071     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms1722     Document Type: Article

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