Quercetin protects against Okadaic acid-induced injury via MAPK and PI3K/Akt/GSK3β signaling pathways in HT22 hippocampal neurons

PLoS ONE

Volumn 11, Issue 4, 2016, Pages

  Jiang, Wei ^a,b   Luo, Tao ^a   Li, Sheng ^a   Zhou, Yue ^a   Shen, Xiu Yin ^a   He, Feng ^c   Xu, Jie ^a   Wang, Hua Qiao ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b Zhaoqing Medical College   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; GLUTATHIONE PEROXIDASE; GLYCOGEN SYNTHASE KINASE 3BETA; LACTATE DEHYDROGENASE; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE; OKADAIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN KINASE B; QUERCETIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TAU PROTEIN; TRANSCRIPTION FACTOR RELA; GLYCOGEN SYNTHASE KINASE 3; GSK3B PROTEIN, MOUSE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN CELL; CELL DAMAGE; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INHIBITION; HT22 CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CELL LINE; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; HIPPOCAMPUS; METABOLISM; NERVE CELL; PHOSPHORYLATION;

ANIMALS; CELL LINE; GLUTATHIONE PEROXIDASE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; HIPPOCAMPUS; MAP KINASE SIGNALING SYSTEM; MICE; NEURONS; OKADAIC ACID; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; QUERCETIN; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TAU PROTEINS;

EID: 84962866771     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0152371     Document Type: Article

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