The novel mitochondria-targeted antioxidant SkQ1 modulates angiogenesis and inflammatory micromilieu in a murine orthotopic model of pancreatic cancer

International Journal of Cancer

Volumn 139, Issue 1, 2016, Pages 130-139

  Bazhin, Alexandr V ^a   Yang, Yuhui ^b   D'Haese, Jan G ^a   Werner, Jens ^a   Philippov, Pavel P ^c   Karakhanova, Svetlana ^d  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c MOSCOW STATE UNIVERSITY   (Russian Federation)

^d UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

angiogenesis; immune regulation; PDAC; ROS; SkQ1

Indexed keywords

10 (6' PLASTOQUINONYL)DECYLTRIPHENYLPHOSPHONIUM; ALPHA INTERFERON; AMPHIREGULIN; ANGIOGENIC FACTOR; ANGIOPOIETIN; ANTIOXIDANT; BETACELLULIN; ENDOGLIN; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; LEPTIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; PROLACTIN; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VASCULOTROPIN; 10-(6'-PLASTOQUINONYL)DECYLTRIPHENYLPHOSPHONIUM; PLASTOQUINONE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CANCER IMMUNOLOGY; CANCER MODEL; CANCER SURVIVAL; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; DRUG TREATMENT FAILURE; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOREGULATION; LIVER METASTASIS; LYMPHOCYTE COUNT; MEMORY T LYMPHOCYTE; MITOCHONDRION; MOUSE; MOUSE MODEL; NATURAL KILLER T CELL; NONHUMAN; ORTHOTOPIC TRANSPLANTATION; PANC02 CELL LINE; PANCREAS ADENOCARCINOMA; PANCREATIC CANCER CELL LINE; PERITONEUM METASTASIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; TISSUE LEVEL; TUMOR VASCULARIZATION; UPREGULATION; ADENOCARCINOMA; ANALOGS AND DERIVATIVES; ANIMAL; CARCINOMA, PANCREATIC DUCTAL; DRUG EFFECTS; INFLAMMATION; METABOLISM; NEOVASCULARIZATION, PATHOLOGIC; PATHOLOGY; SIGNAL TRANSDUCTION;

ADENOCARCINOMA; ANIMALS; ANTIOXIDANTS; CARCINOMA, PANCREATIC DUCTAL; HUMANS; INFLAMMATION; MICE; MITOCHONDRIA; NEOVASCULARIZATION, PATHOLOGIC; PLASTOQUINONE; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84962859038     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.30054     Document Type: Article

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