메뉴 건너뛰기




Volumn 52, Issue 1, 2012, Pages 19-29

In vivo immunoregulatory properties of the novel mitochondria-targeted antioxidant SkQ1

Author keywords

Immune cells; Reactive oxygen species; SkQ1

Indexed keywords

ANTIOXIDANT; IMMUNOMODULATING AGENT; SKQ1; UNCLASSIFIED DRUG;

EID: 84860806851     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2012.04.010     Document Type: Article
Times cited : (26)

References (34)
  • 2
    • 0015596284 scopus 로고
    • Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent
    • Babior B.M., Kipnes R.S., Curnutte J.T. Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent. Journal of Clinical Investigation 1973, 52:741-744.
    • (1973) Journal of Clinical Investigation , vol.52 , pp. 741-744
    • Babior, B.M.1    Kipnes, R.S.2    Curnutte, J.T.3
  • 6
    • 0022978272 scopus 로고
    • Effect of antioxidants on primary alloantigen-induced T cell activation and proliferation
    • Chaudhri G., Clark I.A., Hunt N.H., Cowden W.B., Ceredig R. Effect of antioxidants on primary alloantigen-induced T cell activation and proliferation. Journal of Immunology 1986, 137:2646-2652.
    • (1986) Journal of Immunology , vol.137 , pp. 2646-2652
    • Chaudhri, G.1    Clark, I.A.2    Hunt, N.H.3    Cowden, W.B.4    Ceredig, R.5
  • 7
    • 0023740171 scopus 로고
    • Antioxidants inhibit proliferation and cell surface expression of receptors for interleukin-2 and transferrin in T lymphocytes stimulated with phorbol myristate acetate and ionomycin
    • Chaudhri G., Hunt N.H., Clark I.A., Ceredig R. Antioxidants inhibit proliferation and cell surface expression of receptors for interleukin-2 and transferrin in T lymphocytes stimulated with phorbol myristate acetate and ionomycin. Cellular Immunology 1988, 115:204-213.
    • (1988) Cellular Immunology , vol.115 , pp. 204-213
    • Chaudhri, G.1    Hunt, N.H.2    Clark, I.A.3    Ceredig, R.4
  • 9
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • Droge W. Free radicals in the physiological control of cell function. Physiological Reviews 2002, 82:47-95.
    • (2002) Physiological Reviews , vol.82 , pp. 47-95
    • Droge, W.1
  • 10
    • 0023258794 scopus 로고
    • Modulation of intracellular glutathione concentrations alters lymphocyte activation and proliferation
    • Fidelus R.K., Ginouves P., Lawrence D., Tsan M.F. Modulation of intracellular glutathione concentrations alters lymphocyte activation and proliferation. Experimental Cell Research 1987, 170:269-275.
    • (1987) Experimental Cell Research , vol.170 , pp. 269-275
    • Fidelus, R.K.1    Ginouves, P.2    Lawrence, D.3    Tsan, M.F.4
  • 12
    • 4444221709 scopus 로고    scopus 로고
    • T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation
    • Jackson S.H., Devadas S., Kwon J., Pinto L.A., Williams M.S. T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation. Nature Immunology 2004, 5:818-827.
    • (2004) Nature Immunology , vol.5 , pp. 818-827
    • Jackson, S.H.1    Devadas, S.2    Kwon, J.3    Pinto, L.A.4    Williams, M.S.5
  • 15
    • 0142075336 scopus 로고    scopus 로고
    • T cell receptor-stimulated generation of hydrogen peroxide inhibits MEK-ERK activation and lck serine phosphorylation
    • Kwon J., Devadas S., Williams M.S. T cell receptor-stimulated generation of hydrogen peroxide inhibits MEK-ERK activation and lck serine phosphorylation. Free Radical Biology and Medicine 2003, 35:406-417.
    • (2003) Free Radical Biology and Medicine , vol.35 , pp. 406-417
    • Kwon, J.1    Devadas, S.2    Williams, M.S.3
  • 16
    • 0031936187 scopus 로고    scopus 로고
    • Pre-exposure to oxidative stress decreases the nuclear factor-kappa B-dependent transcription in T lymphocytes
    • Lahdenpohja N., Savinainen K., Hurme M. Pre-exposure to oxidative stress decreases the nuclear factor-kappa B-dependent transcription in T lymphocytes. Journal of Immunology 1998, 160:1354-1358.
    • (1998) Journal of Immunology , vol.160 , pp. 1354-1358
    • Lahdenpohja, N.1    Savinainen, K.2    Hurme, M.3
  • 18
    • 77951279075 scopus 로고    scopus 로고
    • Reactive oxygen species in cancer
    • Liou G.Y., Storz P. Reactive oxygen species in cancer. Free Radical Research 2010, 44:479-496.
    • (2010) Free Radical Research , vol.44 , pp. 479-496
    • Liou, G.Y.1    Storz, P.2
  • 20
    • 65349093464 scopus 로고    scopus 로고
    • Naturally occurring regulatory T cells show reduced sensitivity toward oxidative stress-induced cell death
    • Mougiakakos D., Johansson C.C., Kiessling R. Naturally occurring regulatory T cells show reduced sensitivity toward oxidative stress-induced cell death. Blood 2009, 113:3542-3545.
    • (2009) Blood , vol.113 , pp. 3542-3545
    • Mougiakakos, D.1    Johansson, C.C.2    Kiessling, R.3
  • 21
    • 33847071146 scopus 로고    scopus 로고
    • Targeting antioxidants to mitochondria by conjugation to lipophilic cations
    • Murphy M.P., Smith R.A. Targeting antioxidants to mitochondria by conjugation to lipophilic cations. Annual Review of Pharmacology and Toxicology 2007, 47:629-656.
    • (2007) Annual Review of Pharmacology and Toxicology , vol.47 , pp. 629-656
    • Murphy, M.P.1    Smith, R.A.2
  • 23
    • 0036911138 scopus 로고    scopus 로고
    • Hydrogen peroxide as second messenger in lymphocyte activation
    • Reth M. Hydrogen peroxide as second messenger in lymphocyte activation. Nature Immunology 2002, 3:1129-1134.
    • (2002) Nature Immunology , vol.3 , pp. 1129-1134
    • Reth, M.1
  • 25
    • 2142730100 scopus 로고    scopus 로고
    • Central memory and effector memory T cell subsets: function, generation, and maintenance
    • Sallusto F., Geginat J., Lanzavecchia A. Central memory and effector memory T cell subsets: function, generation, and maintenance. Annual Review of Immunology 2004, 22:745-763.
    • (2004) Annual Review of Immunology , vol.22 , pp. 745-763
    • Sallusto, F.1    Geginat, J.2    Lanzavecchia, A.3
  • 26
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto F., Lenig D., Forster R., Lipp M., Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999, 401:708-712.
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 27
    • 0035874990 scopus 로고    scopus 로고
    • Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer patients
    • Schmielau J., Finn O.J. Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer patients. Cancer Research 2001, 61:4756-4760.
    • (2001) Cancer Research , vol.61 , pp. 4756-4760
    • Schmielau, J.1    Finn, O.J.2
  • 28
    • 77951897238 scopus 로고    scopus 로고
    • Reactive oxygen species level defines two functionally distinctive stages of inflammatory dendritic cell development from mouse bone marrow
    • Sheng K.C., Pietersz G.A., Tang C.K., Ramsland P.A., Apostolopoulos V. Reactive oxygen species level defines two functionally distinctive stages of inflammatory dendritic cell development from mouse bone marrow. Journal of Immunology 2010, 184:2863-2872.
    • (2010) Journal of Immunology , vol.184 , pp. 2863-2872
    • Sheng, K.C.1    Pietersz, G.A.2    Tang, C.K.3    Ramsland, P.A.4    Apostolopoulos, V.5
  • 29
    • 79956105098 scopus 로고    scopus 로고
    • Normal T cell homeostasis: the conversion of naive cells into memory-phenotype cells
    • Sprent J., Surh C.D. Normal T cell homeostasis: the conversion of naive cells into memory-phenotype cells. Nature Immunology 2011, 12:478-484.
    • (2011) Nature Immunology , vol.12 , pp. 478-484
    • Sprent, J.1    Surh, C.D.2
  • 31
    • 4444240314 scopus 로고    scopus 로고
    • T cell receptor stimulation, reactive oxygen species, and cell signaling
    • Williams M.S., Kwon J. T cell receptor stimulation, reactive oxygen species, and cell signaling. Free Radical Biology and Medicine 2004, 37:1144-1151.
    • (2004) Free Radical Biology and Medicine , vol.37 , pp. 1144-1151
    • Williams, M.S.1    Kwon, J.2
  • 32
    • 0033506266 scopus 로고    scopus 로고
    • Beta-Carotene and selenium supplementation enhances immune response in aged humans
    • Wood S.M., Beckham C., Yosioka A., Darban H., Watson R.R. beta-Carotene and selenium supplementation enhances immune response in aged humans. Integrative Medicine 2000, 2:85-92.
    • (2000) Integrative Medicine , vol.2 , pp. 85-92
    • Wood, S.M.1    Beckham, C.2    Yosioka, A.3    Darban, H.4    Watson, R.R.5
  • 33
    • 34250159927 scopus 로고    scopus 로고
    • Development of dendritic-cell lineages
    • Wu L., Liu Y.J. Development of dendritic-cell lineages. Immunity 2007, 26:741-750.
    • (2007) Immunity , vol.26 , pp. 741-750
    • Wu, L.1    Liu, Y.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.