Roles of myofibroblasts in prostaglandin E2-stimulated intestinal epithelial proliferation and angiogenesis

Cancer Research

Volumn 66, Issue 2, 2006, Pages 846-855

  Shao, Jinyi ^a   Sheng, George G ^b   Mifflin, Randy C ^c   Powell, Don W ^c   Sheng, Hongmiao ^a,d  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

^d INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIREGULIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; GROWTH FACTOR; MESSENGER RNA; NEU DIFFERENTIATION FACTOR; NEUTRALIZING ANTIBODY; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROSTANOID RECEPTOR; SCATTER FACTOR; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELL TRANSFORMATION; COLON MUCOSA; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; INFLAMMATION; INTESTINE EPITHELIUM; INTESTINE TUMOR; MYOFIBROBLAST; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

CELL CULTURE TECHNIQUES; CELL MOVEMENT; CELL PROLIFERATION; DINOPROSTONE; FIBROBLASTS; GROWTH SUBSTANCES; HOMEOSTASIS; HUMANS; INFLAMMATION; INTESTINAL MUCOSA; INTESTINAL NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC;

EID: 31544465706     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-2606     Document Type: Article

References (62)

1. Mohajer B, Ma TY. Eicosanoids and the small intestine. Prostaglandins Other Lipid Mediat 2000;61: 125-43.
2. Krause W, DuBois RN. Eicosanoids and the large intestine. Prostaglandins Other Lipid Mediat 2000;61: 145-61.
3. 2 prostaglandins modulate cell proliferation in the small intestinal epithelium of the rat. Digestion 1992;52:157-64.
4. Dembinski A, Konturek SJ. Effects of E, F, and I series prostaglandins and analogues on growth of gastroduodenal mucosa and pancreas. Am J Physiol 1985;248: G170-5.
5. 2 have a synergistic role in rescuing epithelial barrier function in porcine ileum. J Clin Invest 1997;100:1928-33.
6. 2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy. Nat Med 2002;8:289-93.
7. 2 enhances intestinal adenoma growth via activation of the Ras-mitogen-activated protein kinase cascade. Cancer Res 2005;65:1822-9.
8. Oshima M, Dinchuk JE, Kargman S, et al. Suppression of intestinal polyposis in ApcD716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 1996;87: 803-9.
9. 2 in Apc(Delta 716) knockout mice. Nat Med 2001;7: 1048-51.
10. Tsujii M, Kawano S, Tsuji S, et al. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 1998;93:705-16.
11. Williams CS, Tsujii M, Reese J, et al. Host cyclooxygenase-2 modulates carcinoma growth. J Clin Invest 2000;105:1589-94.
12. Oshima M, Murai N, Kargman S, et al. Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor. Cancer Res 2001;61:1733-40.
13. Sheng H, Shao J, Kirkland SC, et al. Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2. J Clin Invest 1997;99:2254-9.
14. 2 increases growth and motility of colorectal carcinoma cells. J Biol Chem 2001;276:18075-81.
15. 2 is mediated by hypoxia-inducible factor 1. Cancer Res 2003;63:2330-4.
16. 2 stimulates the b-catenin/T cell factor-dependent transcription in colon cancer. J Biol Chem 2005;280: 26565-72.
17. Elenbaas B, Weinberg RA. Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation. Exp Cell Res 2001;264:169-84.
18. Finch PW, Cunha GR, Rubin JS, et al. Pattern of keratinocyte growth factor and keratinocyte growth factor receptor expression during mouse fetal development suggests a role in mediating morphogenetic mesenchymal-epithelial interactions. Dev Dyn 1995; 203:223-40.
19. Fritsch C, Simon-Assmann P, Kedinger M, Evans GS. Cytokines modulate fibroblast phenotype and epithelial-stroma interactions in rat intestine. Gastroenterology 1997;112:826-38.
20. Powell DW, Mifflin RC, Valentich JD, et al. Myofibroblasts. I. Paracrine cells important in health and disease. Am J Physiol 1999;277:C1-9.
21. Powell DW, Mifflin RC, Valentich JD, et al. Myofibroblasts. II. Intestinal subepithelial myofibroblasts. Am J Physiol 1999;277:C183-201.
22. Wallace JL, Granger DN. The cellular and molecular basis of gastric mucosal defense. FASEB J 1996; 10:731-40.
23. Kaye GI, Pascal RR, Lane N. The colonic pericryptal fibroblast sheath: replication, migration, and cytodifferentiation of a mesenchymal cell system in adult tissue. 3. Replication and differentiation in human hyperplastic and adenomatous polyps. Gastroenterology 1971;60: 515-36.
24. Joyce NC, Haire MF, Palade GE. Morphologic and biochemical evidence for a contractile cell network within the rat intestinal mucosa. Gastroenterology 1987; 92:68-81.
25. Bradbury J. A two-pronged approach to the clinical use of HGF. Lancet 1998;351:272.
26. Miller SM, Farrugia G, Schmalz PF, et al. Heme oxygenase 2 is present in interstitial cell networks of the mouse small intestine. Gastroenterology 1998;114: 239-44.
27. Berndt A, Kosmehl H, Mandel U, et al. TGF β and bFGF synthesis and localization in Dupuytren's disease (nodular palmar fibromatosis) relative to cellular activity, myofibroblast phenotype and oncofetal variants of fibronectin. Histochem J 1995;27:1014-20.
28. Bostrom H, Willetts K, Pekny M, et al. PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis. Cell 1996;85:863-73.
29. Border WA, Noble NA. Transforming growth factor β in tissue fibrosis. N Engl J Med 1994;331:1286-92.
30. Pfeilschifter J. Mesangial cells orchestrate inflammation in the renal glomerulus. News Physiol Sci 1994;9: 271-6.
31. Klimpel GR, Langley KE, Wypych J, et ai. A role for stem cell factor (SCF): c-kit interaction(s) in the intestinal tract response to Salmonella typhimurium infection. J Exp Med 1996;184:271-6.
32. Adegboyega PA, Mifflin RC, DiMari JF, et al. Immunohistochemical study of myofibroblasts in normal colonic mucosa, hyperplastic polyps, and adenomatous colorectal polyps. Arch Pathol Lab Med 2002; 126:829-36.
33. Valentich JD, Popov V, Saada JI, Powell DW. Phenotypic characterization of an intestinal subepithelial myofibroblast cell line. Am J Physiol 1997;272: C1513-24.
34. Mifflin RC, Saada JI, Di Mari JF, et al. Regulation of COX-2 expression in human intestinal myofibroblasts: mechanisms of IL-1-mediated induction. Am J Physiol Cell Physiol 2002;282:C824-34.
35. Hinterleitner TA, Saada JI, Berschneider HM, et al. IL-1 stimulates intestinal myofibroblast COX gene expression and augments activation of C1- secretion in T84 cells. Am J Physiol 1996;271:C1262-8.
36. Mahida YR, Galvin AM, Gray T, et al. Migration of human intestinal lamina propria lymphocytes, macrophages and eosinophils following the loss of surface epithelial cells. Clin Exp Immunol 1997;109: 377-86.
37. Mahida YR, Beltinger J, Makh S, et al. Adult human colonie subepithelial myofibroblasts express extracellular matrix proteins and cyclooxygenase-1 and -2. Am J Physiol 1997;273:G1341-8.
38. Gamble JR, Matthias LJ, Meyer G, et al. Regulation of in vitro capillary tube formation by anti-integrin antibodies. J Cell Biol 1993;121:931-43.
39. 2 stimulates the growth of colon cancer cells via induction of amphiregulin. Cancer Res 2003;63:5218-23.
40. Furuya S, Furuya K. Characteristics of cultured subepithelial fibroblasts of rat duodenal villi. Anat Embryol (Berl) 1993;187:529-38.
41. Breyer MD, Breyer RM. Prostaglandin receptors: their role in regulating renal function. Curr Opin Nephrol Hypertens 2000;9:23-9.
42. Ramakers GJ, Moolenaar WH. Regulation of astrocyte morphology by RhoA and lysophosphatidic acid. Exp Cell Res 1998;245:252-62.
43. Dempsey PJ, Coffey RJ. Basolateral targeting and efficient consumption of transforming growth factor-α when expressed in Madin-Darby canine kidney cells. J Biol Chem 1994;269:16878-89.
44. Damstrup L, Kuwada SK, Dempsey PJ, et al. Amphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis. Br J Cancer 1999;80:1012-9.
45. Sheng H, Shao J, Townsend CM, Jr., Evers BM. Phosphatidylinositol 3-kinase mediates proliferative signals in intestinal epithelial cells. Gut 2003;52:1472-8.
46. Olaso E, Salado C, Egilegor E, et al. Proangiogenic role of tumor-activated hepatic stellate cells in experimental melanoma metastasis. Hepatology 2003; 37:674-85.
47. Williams CS, Mann M, DuBois RN. The role of cyclooxygenases in inflammation, cancer, and development. Oncogene 1999;18:7908-16.
48. Eberhart CE, Coffey RJ, Radhika A, et al. Upregulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 1994;107:1183-8.
49. Kargman SL, O'Neill GP, Vickers PJ, et al. Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer. Cancer Res 1995;55:2556-9.
50. Chapple KS, Cartwright EJ, Hawcroft G, et al. Localization of cyclooxygenase-2 in human sporadic colorectal adenomas. Am J Pathol 2000;156:545-53.
51. Shao J, Sheng H, Inoue H, et al. Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells. J Biol Chem 2000;275:33951-6.
52. Ribardo DA, Crowe SE, Kuhl KR, et ai. Prostaglandin levels in stimulated macrophages are controlled by phospholipase A2-activating protein and by activation of phospholipase C and D. J Biol Chem 2001; 276:5467-75.
53. Berasain C, Garcia-Trevijano ER, Castillo J, et al. Amphiregulin: an early trigger of liver regeneration in mice. Gastroenterology 2005;128:424-32.
54. Ciardiello F, Kim N, Saeki T, et al. Differential expression of epidermal growth factor-related proteins in human colorectal tumors. Proc Natl Acad Sci U S A 1991;88:7792-6.
55. De Luca A, Arra C, DAntonio A, et al. Simultaneous blockage of different EGF-like growth factors results in efficient growth inhibition of human colon carcinoma xenografts. Oncogene 2000;19:5863-71.
56. 2 synergistically enhances receptor tyrosine kinase-dependent signaling system in colon cancer cells. J Biol Chem 2004;279:14287-93.
57. 2 receptor EP2 is required for cyclooxygenase 2-mediated mammary hyperplasia. Cancer Res 2005;65: 4496-9.
58. Moraitis D, Du B, De Lorenzo MS. Levels of cyclooxygenase-2 are increased in the oral mucosa of smokers: evidence for the role of epidermal growth factor receptor and its ligands. Cancer Res 2005;65: 664-70.
59. Matsumoto K, Nakamura T. Hepatocyte growth factor: molecular structure, roles in liver regeneration, and other biological functions. Crit Rev Oncog 1992; 3:27-54.
60. Di Renzo MF, Narsimhan RP, Olivero M, et al. M. Expression of the Met/HGF receptor in normal and neoplastic human tissues. Oncogene 1991;6:1997-2003.
61. Halttunen T, Marttinen A, Rantala I, et al. Fibroblasts and transforming growth factor β induce organization and differentiation of T84 human epithelial cells. Gastroenterology 1996;111:1252-62.
62. Kiriyama M, Ushikubi F, Kobayashi T, et al. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol 1997;122:217-24.