Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity

OncoImmunology

Volumn 5, Issue 4, 2016, Pages

  Hong, Yuan ^a   Manoharan, Indumathi ^a   Suryawanshi, Amol ^a   Shanmugam, Arulkumaran ^a   Swafford, Daniel ^a   Ahmad, Shamim ^a   Chinnadurai, Raghavan ^b   Manicassamy, Balaji ^c   He, Yukai ^a   Mellor, Andrew L ^a   Thangaraju, Muthusamy ^a   Munn, David H ^a   Manicassamy, Santhakumar ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

Antitumor immunity; Dendritic cells; Immune tolerance; LRP5; LRP6; PORCN inhibitor; Wnt

Indexed keywords

BETA CATENIN; CD11 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; FRIZZLED PROTEIN; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 10; INTERLEUKIN 12; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; RETINOIC ACID; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTITUMOR IMMUNITY; ARTICLE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CONTROLLED STUDY; DENDRITIC CELL; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE DELETION; IMMUNE RESPONSE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY T LYMPHOCYTE; TUMOR ASSOCIATED LEUKOCYTE; TUMOR GROWTH; TUMOR MICROENVIRONMENT; WNT SIGNALING PATHWAY;

EID: 84962808865     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.1080/2162402X.2015.1115941     Document Type: Article

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