-
1
-
-
79959947008
-
Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis
-
Goetz, J.G.; Minguet, S.; Navarro-Lérida, I.; Lazcano, J.J.; Samaniego, R.; Calvo, E.; Tello, M.; Osteso-Ibáñez, T.; Pellinen, T.; Echarri, A.;et al. Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis. Cell 2011, 146, 148-163.
-
(2011)
Cell
, vol.146
, pp. 148-163
-
-
Goetz, J.G.1
Minguet, S.2
Navarro-Lérida, I.3
Lazcano, J.J.4
Samaniego, R.5
Calvo, E.6
Tello, M.7
Osteso-Ibáñez, T.8
Pellinen, T.9
Echarri, A.10
-
2
-
-
84864285794
-
Tumor micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
-
Straussman, R.; Morikawa, T.; Shee, K.; Barzily-Rokni, M.; Qian, Z.R.; Du, J.; Davis, A.; Mongare, M.M.; Gould, J.; Frederick, D.T.;et al. Tumor micro-environment elicits innate resistance to RAF inhibitors through HGF secretion. Nature 2012, 487, 500-504.
-
(2012)
Nature
, vol.487
, pp. 500-504
-
-
Straussman, R.1
Morikawa, T.2
Shee, K.3
Barzily-Rokni, M.4
Qian, Z.R.5
Du, J.6
Davis, A.7
Mongare, M.M.8
Gould, J.9
Frederick, D.T.10
-
3
-
-
78149298209
-
Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha
-
Kraman, M.; Bambrough, P.J.; Arnold, J.N.; Roberts, E.W.; Magiera, L.; Jones, J.O.; Gopinathan, A.; Tuveson, D.A.; Fearon, D.T. Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha. Science 2010, 330, 827-830.
-
(2010)
Science
, vol.330
, pp. 827-830
-
-
Kraman, M.1
Bambrough, P.J.2
Arnold, J.N.3
Roberts, E.W.4
Magiera, L.5
Jones, J.O.6
Gopinathan, A.7
Tuveson, D.A.8
Fearon, D.T.9
-
4
-
-
84868640245
-
The tumor microenvironment controls drug sensitivity
-
Ostman, A. The tumor microenvironment controls drug sensitivity. Nat. Med. 2012, 18, 1332-1334.
-
(2012)
Nat. Med.
, vol.18
, pp. 1332-1334
-
-
Ostman, A.1
-
5
-
-
84858590826
-
Accessories to the crime: Functions of cells recruited to the tumor microenvironment
-
Hanahan, D.; Coussens, L.M. Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell 2012, 21, 309-322.
-
(2012)
Cancer Cell
, vol.21
, pp. 309-322
-
-
Hanahan, D.1
Coussens, L.M.2
-
6
-
-
84863171290
-
Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment
-
Guzman-Rojas, L.; Rangel, R.; Salameh, A.; Edwards, J.K.; Dondossola, E.; Kim, Y.G.; Saghatelian, A.; Giordano, R.J.; Kolonin, M.G.; Staquicini, F.I.;et al. Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment. Proc. Natl. Acad. Sci. USA 2012, 109, 1637-1642.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 1637-1642
-
-
Guzman-Rojas, L.1
Rangel, R.2
Salameh, A.3
Edwards, J.K.4
Dondossola, E.5
Kim, Y.G.6
Saghatelian, A.7
Giordano, R.J.8
Kolonin, M.G.9
Staquicini, F.I.10
-
7
-
-
80053401068
-
Breast cancer stem cells, cytokine networks, and the tumor microenvironment
-
Korkaya, H.; Liu, S.; Wicha, M.S. Breast cancer stem cells, cytokine networks, and the tumor microenvironment. J. Clin. Investig. 2011, 121, 3804-3809.
-
(2011)
J. Clin. Investig.
, vol.121
, pp. 3804-3809
-
-
Korkaya, H.1
Liu, S.2
Wicha, M.S.3
-
8
-
-
84861116448
-
Tumor microenvironment complexity: Emerging roles in cancer therapy
-
Swartz, M.A.; Iida, N.; Roberts, E.W.; Sangaletti, S.; Wong, M.H.; Yull, F.E.; Coussens, L.M.; DeClerck, Y.A. Tumor microenvironment complexity: emerging roles in cancer therapy. Cancer Res. 2012, 72, 2473-2480.
-
(2012)
Cancer Res.
, vol.72
, pp. 2473-2480
-
-
Swartz, M.A.1
Iida, N.2
Roberts, E.W.3
Sangaletti, S.4
Wong, M.H.5
Yull, F.E.6
Coussens, L.M.7
DeClerck, Y.A.8
-
9
-
-
9244227134
-
Stromal fibroblasts incancer initiation and progression
-
Bhowmick, N.A.; Neilson, E.G.; Moses, H.L. Stromal fibroblasts incancer initiation and progression. Nature 2004, 432, 332-337.
-
(2004)
Nature
, vol.432
, pp. 332-337
-
-
Bhowmick, N.A.1
Neilson, E.G.2
Moses, H.L.3
-
10
-
-
34548124866
-
High glucose enhances MMP-2 production in adventitial fibroblasts via Akt1-dependent NF-kappaB pathway
-
Lee, S.J.; Bae, S.S.; Kim, K.H.; Lee, W.S.; Rhim, B.Y.; Hong, K.W.; Kim, C.D. High glucose enhances MMP-2 production in adventitial fibroblasts via Akt1-dependent NF-kappaB pathway. FEBS Lett. 2007, 581, 4189-4194.
-
(2007)
FEBS Lett.
, vol.581
, pp. 4189-4194
-
-
Lee, S.J.1
Bae, S.S.2
Kim, K.H.3
Lee, W.S.4
Rhim, B.Y.5
Hong, K.W.6
Kim, C.D.7
-
11
-
-
77950931419
-
Matrix metalloproteinases: Regulators of the tumor microenvironment
-
Kessenbrock, K.; Plaks, V.; Werb, Z. Matrix metalloproteinases: Regulators of the tumor microenvironment. Cell 2010, 141, 52-67.
-
(2010)
Cell
, vol.141
, pp. 52-67
-
-
Kessenbrock, K.1
Plaks, V.2
Werb, Z.3
-
12
-
-
79251586559
-
Breast cancer cells induce cancer-associated fibroblasts to secrete hepatocyte growth factor to enhance breast tumorigenesis
-
Tyan, S.W.; Kuo, W.H.; Huang, C.K.; Pan, C.C.; Shew, J.Y.; Chang, K.J.; Lee, E.Y.; Lee, W.H. Breast cancer cells induce cancer-associated fibroblasts to secrete hepatocyte growth factor to enhance breast tumorigenesis. PLoS One 2011, 6, e15313.
-
(2011)
PLoS One
, vol.6
-
-
Tyan, S.W.1
Kuo, W.H.2
Huang, C.K.3
Pan, C.C.4
Shew, J.Y.5
Chang, K.J.6
Lee, E.Y.7
Lee, W.H.8
-
13
-
-
33749549246
-
Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence
-
Coppé, J.P.; Kauser, K.; Campisi, J.; Beauséjour, C.M. Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence. J. Biol. Chem. 2006, 281, 29568-29574.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 29568-29574
-
-
Coppé, J.P.1
Kauser, K.2
Campisi, J.3
Beauséjour, C.M.4
-
14
-
-
84868633053
-
Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B
-
Sun, Y.; Campisi, J.; Higano, C.; Beer, T.M.; Porter, P.; Coleman, I.; True, L.; Nelson, P.S. Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B. Nat. Med. 2012, 18, 1359-1368.
-
(2012)
Nat. Med.
, vol.18
, pp. 1359-1368
-
-
Sun, Y.1
Campisi, J.2
Higano, C.3
Beer, T.M.4
Porter, P.5
Coleman, I.6
True, L.7
Nelson, P.S.8
-
15
-
-
73649118223
-
WNT16B is a new marker of cellular senescence that regulates p53 activity and the phosphoinositide 3-kinase/AKT pathway
-
Binet, R.; Ythier, D.; Robles, A.I.; Collado, M.; Larrieu, D.; Fonti, C.; Brambilla, E.; Brambilla, C.; Serrano, M.; Harris, C.C.;et al. WNT16B is a new marker of cellular senescence that regulates p53 activity and the phosphoinositide 3-kinase/AKT pathway. Cancer Res. 2009, 69, 9183-9191.
-
(2009)
Cancer Res.
, vol.69
, pp. 9183-9191
-
-
Binet, R.1
Ythier, D.2
Robles, A.I.3
Collado, M.4
Larrieu, D.5
Fonti, C.6
Brambilla, E.7
Brambilla, C.8
Serrano, M.9
Harris, C.C.10
-
16
-
-
24044490922
-
Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis
-
Mazieres, J.; You, L.; He, B.; Xu, Z.; Lee, A.Y.; Mikami, I.; McCormick, F.; Jablons, D.M. Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis. Oncogene 2005, 24, 5396-5400.
-
(2005)
Oncogene
, vol.24
, pp. 5396-5400
-
-
Mazieres, J.1
You, L.2
He, B.3
Xu, Z.4
Lee, A.Y.5
Mikami, I.6
McCormick, F.7
Jablons, D.M.8
-
17
-
-
84856934228
-
Rationale behind targeting fibroblast activation protein-expressing carcinoma-associated fibroblasts as a novel chemotherapeutic strategy
-
Brennen, W.N.; Isaacs, J.T.; Denmeade, S.R. Rationale behind targeting fibroblast activation protein-expressing carcinoma-associated fibroblasts as a novel chemotherapeutic strategy. Mol. Cancer Ther. 2012, 11, 257-266.
-
(2012)
Mol. Cancer Ther.
, vol.11
, pp. 257-266
-
-
Brennen, W.N.1
Isaacs, J.T.2
Denmeade, S.R.3
-
18
-
-
79959713140
-
Fibroblast growth factors and their receptors in cancer
-
Wesche, J.; Haglund, K.; Haugsten, E.M. Fibroblast growth factors and their receptors in cancer. Biochem. J. 2011, 437, 199-213.
-
(2011)
Biochem. J.
, vol.437
, pp. 199-213
-
-
Wesche, J.1
Haglund, K.2
Haugsten, E.M.3
-
19
-
-
30544450198
-
Radiation induced DNA damage and damage repair in human tumor and fibroblast cell lines assessed by histone H2AX phosphorylation
-
Mahrhofer, H.; Bürger, S.; Oppitz, U.; Flentje, M.; Djuzenova, C.S. Radiation induced DNA damage and damage repair in human tumor and fibroblast cell lines assessed by histone H2AX phosphorylation. Int. J. Radiat. Oncol. Biol. Phys. 2006, 64, 573-580.
-
(2006)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.64
, pp. 573-580
-
-
Mahrhofer, H.1
Bürger, S.2
Oppitz, U.3
Flentje, M.4
Djuzenova, C.S.5
-
20
-
-
33845982557
-
Hydrogen sulfide-induces DNA damage and changes in apoptotic gene expression in human lung fibroblast cells
-
Baskar, R.; Li, L.; Moore, P.K. Hydrogen sulfide-induces DNA damage and changes in apoptotic gene expression in human lung fibroblast cells. FASEB J. 2007, 21, 247-255.
-
(2007)
FASEB J.
, vol.21
, pp. 247-255
-
-
Baskar, R.1
Li, L.2
Moore, P.K.3
-
21
-
-
24644481372
-
Fibroblast differentiation of bone marrow-derived cells during wound repair
-
Opalenik, S.R.; Davidson, J.M. Fibroblast differentiation of bone marrow-derived cells during wound repair. FASEB J. 2005, 19, 1561-1563.
-
(2005)
FASEB J.
, vol.19
, pp. 1561-1563
-
-
Opalenik, S.R.1
Davidson, J.M.2
-
22
-
-
13244272361
-
The novel cytokine p43 stimulates dermal fibroblast proliferation and wound repair
-
Park, S.G.; Shin, H.; Shin, Y.K.; Lee, Y.; Choi, E.C.; Park, B.J.; Kim, S. The novel cytokine p43 stimulates dermal fibroblast proliferation and wound repair. Am. J. Pathol. 2005, 166, 387-398.
-
(2005)
Am. J. Pathol.
, vol.166
, pp. 387-398
-
-
Park, S.G.1
Shin, H.2
Shin, Y.K.3
Lee, Y.4
Choi, E.C.5
Park, B.J.6
Kim, S.7
-
23
-
-
35148859739
-
Adenomatous polyposis coli-mediated hypersensitivity of mouse embryonic fibroblast cell lines to methylmethane sulfonate treatment: Implication of base excision repair pathways
-
Kundu, C.N.; Balusu, R.; Jaiswal, A.S.; Narayan, S. Adenomatous polyposis coli-mediated hypersensitivity of mouse embryonic fibroblast cell lines to methylmethane sulfonate treatment: Implication of base excision repair pathways. Carcinogenesis 2007, 28, 2089-2095.
-
(2007)
Carcinogenesis
, vol.28
, pp. 2089-2095
-
-
Kundu, C.N.1
Balusu, R.2
Jaiswal, A.S.3
Narayan, S.4
-
24
-
-
0342264524
-
Dose-dependent induction of transforming growth factor beta (TGF-β) in the lung tissue of fibrosis-prone mice after thoracic irradiation
-
Rube, C.E.; Uthe, D.; Schmid, K.W.; Richter, K.D.; Wessel, J.; Schuck, A.; Willich, N.; Rube, C. Dose-dependent induction of transforming growth factor beta (TGF-β) in the lung tissue of fibrosis-prone mice after thoracic irradiation. Int. J. Radiat. Oncol. Biol. Phys. 2000, 47, 1033-1042.
-
(2000)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.47
, pp. 1033-1042
-
-
Rube, C.E.1
Uthe, D.2
Schmid, K.W.3
Richter, K.D.4
Wessel, J.5
Schuck, A.6
Willich, N.7
Rube, C.8
-
25
-
-
20244364391
-
Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis
-
Abdollahi, A.; Li, M.; Ping, G.; Plathow, C.; Domhan, S.; Kiessling, F.; Lee, L.B.; McMahon, G.; Gröne, H.J.; Lipson, K.E.;et al. Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis.J. Exp. Med. 2005, 201, 925-935.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 925-935
-
-
Abdollahi, A.1
Li, M.2
Ping, G.3
Plathow, C.4
Domhan, S.5
Kiessling, F.6
Lee, L.B.7
McMahon, G.8
Gröne, H.J.9
Lipson, K.E.10
-
27
-
-
84879114342
-
Canonical and noncanonical wnt proteins program dendritic cell responses for tolerance
-
Oderup, C.; Lajevic, M.; Butcher, E.C. Canonical and noncanonical wnt proteins program dendritic cell responses for tolerance. J. Immunol. 2013, 190, 6126-6134.
-
(2013)
J. Immunol.
, vol.190
, pp. 6126-6134
-
-
Oderup, C.1
Lajevic, M.2
Butcher, E.C.3
-
28
-
-
77949425125
-
Generation of tolerogenic dendritic cells via the E-cadherin/β-catenin-signaling pathway
-
Fu, C.; Jiang, A. Generation of tolerogenic dendritic cells via the E-cadherin/β-catenin-signaling pathway. Immunol. Res. 2010, 46, 72-78.
-
(2010)
Immunol. Res.
, vol.46
, pp. 72-78
-
-
Fu, C.1
Jiang, A.2
-
29
-
-
77955634800
-
Activation of beta-cateninin dendritic cellsregulates immunityversustolerance in the intestine
-
Manicassamy, S.; Reizis, B.; Ravindran, R.; Nakaya, H.; Salazar-Gonzalez, R.M.; Wang, Y.C.; Pulendran, B. Activation of beta-cateninin dendritic cellsregulates immunityversustolerance in the intestine. Science 2010, 329, 849-853.
-
(2010)
Science
, vol.329
, pp. 849-853
-
-
Manicassamy, S.1
Reizis, B.2
Ravindran, R.3
Nakaya, H.4
Salazar-Gonzalez, R.M.5
Wang, Y.C.6
Pulendran, B.7
-
30
-
-
17144405680
-
Potential role ofinterleukin-10-secreting regulatory T cells in allergy and asthma
-
Hawrylowicz, C.M.; O'Garra, A. Potential role ofinterleukin-10-secreting regulatory T cells in allergy and asthma. Nat. Rev. Immunol. 2005, 5, 271-283.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 271-283
-
-
Hawrylowicz, C.M.1
O'Garra, A.2
-
31
-
-
84856945806
-
TGF-β: The sword, the wand, and the shieldof FOXP3(+) regulatory T cells
-
Tran, D.Q. TGF-β: The sword, the wand, and the shieldof FOXP3(+) regulatory T cells.J. Mol. Cell. Biol. 2012, 4, 29-37.
-
(2012)
J. Mol. Cell. Biol.
, vol.4
, pp. 29-37
-
-
Tran, D.Q.1
-
32
-
-
84895482825
-
Galectin-9 induced myeloid suppressor cells expand regulatory T cells in an IL-10-dependent manner in CVB3-induced acute myocarditis
-
Zhang, Y.; Jiang, L.; Zhang, M.; Lv, K. Galectin-9 induced myeloid suppressor cells expand regulatory T cells in an IL-10-dependent manner in CVB3-induced acute myocarditis. Int. J. Mol. Sci. 2014, 15, 3356-3372.
-
(2014)
Int. J. Mol. Sci.
, vol.15
, pp. 3356-3372
-
-
Zhang, Y.1
Jiang, L.2
Zhang, M.3
Lv, K.4
|