Pretreatment with fucoidan from fucus vesiculosus protected against cona-induced acute liver injury by inhibiting both intrinsic and extrinsic apoptosis

PLoS ONE

Volumn 11, Issue 4, 2016, Pages

  Li, Jingjing ^a   Chen, Kan ^a   Li, Sainan ^a   Liu, Tong ^a   Wang, Fan ^a   Xia, Yujing ^a   Lu, Jie ^a   Zhou, Yingqun ^a   Guo, Chuanyong ^a  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CASPASE 8; CASPASE 9; CONCANAVALIN A; CYTOKINE; FUCOIDIN; GAMMA INTERFERON; JANUS KINASE 2; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED DEATH DOMAIN PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; PLANT EXTRACT; POLYSACCHARIDE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FUCUS VESICULOSUS; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INCIDENCE; LIVER INJURY; LIVER PROTECTION; MACROPHAGE; MOUSE; NONHUMAN; PATHOGENESIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; T LYMPHOCYTE; TUNEL ASSAY; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; CHEMICAL AND DRUG INDUCED LIVER INJURY; CHEMISTRY; DRUG EFFECTS; FUCUS; MALE; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CHEMICAL AND DRUG INDUCED LIVER INJURY; CONCANAVALIN A; FUCUS; MALE; MICE; MICE, INBRED BALB C; PLANT EXTRACTS; POLYSACCHARIDES; SIGNAL TRANSDUCTION;

EID: 84962674706     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0152570     Document Type: Article

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