Intravenous iron sucrose reverses anemia-induced cardiac remodeling, prevents myocardial fibrosis, and improves cardiac function by attenuating oxidative/nitrosative stress and inflammation

International Journal of Cardiology

Volumn 212, Issue , 2016, Pages 84-91

  Toblli, Jorge E ^a   Cao, Gabriel ^a   Rivas, Carlos ^a   Giani, Jorge F ^b   Dominici, Fernando P ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Cardiac function; Cardiac remodeling; Intravenous iron sucrose; Oxidative stress; Rat

Indexed keywords

CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; HEMOGLOBIN; IRON; IRON SACCHARATE; MALONALDEHYDE; TRANSCRIPTION FACTOR RELA; TRANSFERRIN; TUMOR NECROSIS FACTOR ALPHA; 3-NITROTYROSINE; CARDIOTONIC AGENT; FERRIC ION; FERRIC OXIDE, SACCHARATED; SACCHARIC ACID; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL SIZE; CHEMOPROPHYLAXIS; CONTROLLED STUDY; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART VENTRICLE REMODELING; HEART WEIGHT; HEMOGLOBIN BLOOD LEVEL; INFLAMMATION; IRON BLOOD LEVEL; IRON DEFICIENCY ANEMIA; MALE; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; TRANSFERRIN BLOOD LEVEL; ANALOGS AND DERIVATIVES; ANEMIA; ANIMAL; ANTAGONISTS AND INHIBITORS; CARDIAC MUSCLE; DRUG EFFECTS; FIBROSIS; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; PATHOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANEMIA; ANIMALS; CARDIOTONIC AGENTS; FERRIC COMPOUNDS; FIBROSIS; GLUCARIC ACID; INFLAMMATION; INFUSIONS, INTRAVENOUS; MALE; MYOCARDIUM; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; TYROSINE; VENTRICULAR REMODELING;

EID: 84962636981     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2016.03.039     Document Type: Article

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