β-Adrenergic blockade in developing heart failure: Effects on myocardial inflammatory cytokines, nitric oxide, and remodeling

Circulation

Volumn 101, Issue 17, 2000, Pages 2103-2109

  Prabhu, Sumanth D ^a,b   Chandrasekar, Bysani ^a   Murray, David R ^a   Freeman, Gregory L ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

Adrenergic beta antagonists; Cytokines; Heart failure; Myocardial infarction; Nitric oxide

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; ISOPRENALINE; MESSENGER RNA; METOPROLOL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

ADRENERGIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA ADRENERGIC RECEPTOR BLOCKING; CONTROLLED STUDY; CYTOKINE PRODUCTION; ECHOCARDIOGRAPHY; HEART DILATATION; HEART INFARCTION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE; HEART PAPILLARY MUSCLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 0034595362     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.101.17.2103     Document Type: Article

References (28)

1. Torre-Amione G, Kapadia S, Lee J, Durand J-B, Bies RD, Young JB, Mann DL. Tumor necrosis factor-α and tumor necrosis factor receptors in the failing human heart. Circulation. 1996;93:704-711.
2. Testa M, Yeh M, Lee P, Fanelli R, Loperfido F, Berman JW, LeJemtel T. Circulating levels of cytokines and their endogenous modulators in patients with mild to severe congestive heart failure due to coronary artery disease or hypertension. J Am Coll Cardiol. 1996;28:964-971.
3. 3-adenosine receptors. Am J Physiol. 1999;276:H2141-H2147.
4. Krown KA, Page MT, Nguyen C, Zechner D, Gutierrez V, Comstock KL, Glembotski CC, Quintana PJE, Sabbadini RA. Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes: involvement of the sphingolipid signaling cascade in cardiac cell death. J Clin Invest. 1996;98: 2854-2865.
5. Thaik CM, Calderone A, Takahashi N, Colucci WS. Interleukin-1β modulates the growth and phenotype of neonatal rat cardiac myocytes. J Clin Invest. 1995;96:1093-1099.
6. Yue P, Massie BM, Simpson PC, Long CS. Cytokine expression increases in nonmyocytes from rats with postinfarction heart failure. Am J Physiol. 1998;275:H250-H258.
7. Finkel MS, Oddis CV, Jacob TD, Watkins SC, Hattler BG, Simmons RL. Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science. 1992;257:387-389.
8. Chung MK, Gulick TS, Rotondo RE, Schreiner GF, Lange LG. Mechanism of cytokine inhibition of β-adrenergic agonist stimulation of cyclic AMP in rat cardiac myocytes: impairment of signal transduction. Circ Res. 1990;67:753-763.
9. Yokoyama T, Vaca L, Rossen RD, Durante W, Hazarika P, Mann DL. Cellular basis for the negative inotropic effects of tumor necrosis factor-α in the adult mammalian heart. J Clin Invest. 1993;92:2303-2312.
10. Haywood GA, Tsao PS, von der Leyen HE, Mann MJ, Keeling PJ, Trinidade PT, Lewis NP, Byrne CD, Rickenbacher PR, Bishopric NH, Cooke JP, McKenna WJ, Fowler MB. Expression of inducible nitric oxide synthase in human heart failure. Circulation. 1996;93:1087-1094.
11. Yamamoto S, Tsutui H, Tagawa H, Saito K, Takahashi M, Tada H, Yamamoto M, Katoh M, Egashira K, Takeshita A. Role of myocyte nitric oxide in β-adrenergic hyporesponsiveness in heart failure. Circulation. 1997;95:1111-1114.
12. Balligand J-L, Kelly RA, Marsden PA, Smith TW, Michel T. Control of cardiac muscle cell function by an endogenous nitric oxide signaling system. Proc Natl Acad Sci U S A. 1993;90:347-351.
13. Brady AJB, Warren JB, Poole-Wilson PA, Williams TJ, Harding SE. Nitric oxide attenuates cardiac myocyte contraction. Am J Physiol. 1993; 265:H176-H182.
14. Hare JM, Loh E, Creager MA, Colucci WS. Nitric oxide inhibits the positive inotropic response to β-adrenergic stimulation in humans with left ventricular dysfunction. Circulation. 1995;92:2198-2203.
15. Bristow MR. Mechanisms of action of beta-blocking agents in heart failure. Am J Cardiol. 1997;80:26L-40L.
16. Prabhu SD, Azimi A, Frosto T. Nitric oxide effects on myocardial function and force-interval relations: regulation of twitch duration. J Mol Cell Cardiol. 1999;31:2077-2085.
17. Chandrasekar B, Streitman JE, Colston JT, Freeman GL. Inhibition of nuclear factor κB attenuates proinflammatory cytokine and inducible nitric oxide synthase expression in postischemic myocardium. Biochim Biophys Acta. 1998;1406:91-106.
18. Chandrasekar B, Mitchell DA, Colston JT, Freeman GL. Regulation of CCAAT/enhancer binding protein, interleukin-6, interleukin-6 receptor, and gp130 expression during myocardial ischemia/reperfusion. Circulation. 1999;99:427-433.
19. Cheng XS, Shimokawa H, Momii H, Oyama J, Fukuyama N, Egashira K, Nakazawa H, Takeshita A. Role of superoxide anion in the pathogenesis of cytokine-induced myocardial dysfunction in dogs in vivo. Cardiovasc Res. 1999;42:651-659.
20. Irwin MW, Mak S, Mann DL, Qu R, Penninger JM, Yan A, Dawood F, Wen WH, Shou Z, Liu P. Tissue expression and immunolocalization of tumor necrosis factor-α in postinfarction dysfunctional myocardium. Circulation. 1999;99:1492-1498.
21. Ono K, Matsumori A, Shioi T, Furukawa Y, Sasayama S. Cytokine gene expression after myocardial infarction in rat hearts: possible implication in left ventricular remodeling. Circulation. 1998;98:149-156.
22. Recchia FA, McConnell PI, Bernstein RD, Vogel TR, Xu X, Hintze TH. Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in the conscious dog. Circ Res. 1998;83:969-979.
23. Harding SE, Davies CH, Money-Kyrle AM, Poole-Wilson PA. An inhibitor of nitric oxide synthase does not increase contraction or β-adrenoreceptor sensitivity of ventricular myocytes from failing human heart. Cardiovasc Res. 1998;40:523-529.
24. 3, in plasma after experimental myocardial infarction. J Mol Cell Cardiol. 1997;29:1-9.
25. Kan H, Xie Z, Finkel MS. Norepinephrine-stimulated MAP kinase activity enhances cytokine-induced NO production by rat cardiac myocytes. Am J Physiol. 1999;276:H47-H52.
26. Xing Z, Gauldie J, Cox G, Baumann H, Jordana M, Lei XF, Achong MK. IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses. J Clin Invest. 1998;101:311-320.
27. Heilbrunn SM, Shah P, Bristow MR, Valantine HA, Ginsburg R, Fowler MB. Increased β-receptor density and improved hemodynamic response to catecholamine stimulation during long-term metoprolol therapy in heart failure from dilated cardiomyopathy. Circulation. 1989;79: 483-490.
28. 2-adrenoreceptors in human atrial myocardium. Circ Res. 1990;66:1610-1623.