-
1
-
-
0033599057
-
Disorders of iron metabolism
-
Andrews, N. C. (1999) Disorders of iron metabolism. N. Engl. J. Med. 341, 1986-1995.
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 1986-1995
-
-
Andrews, N.C.1
-
2
-
-
9344224529
-
A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
-
Feder, J. N., Gnirke, A., Thomas, W., Tsuchihashi, Z., Ruddy, D. A., Basava, A., Dormishian, F., Domingo, R., Jr., Ellis, M. C., Fullan, A., Hinton, L. M., Jones, N. L., Kimmel, B. E., Kronmal, G. S., Lauer, P., Lee, V. K., Loeb, D. B., Mapa, F. A., McClelland, E., Meyer, N. C., Mintier, G. A., Moeller, N., Moore, T., Morikang, E., and Wolff, R. K. (1996) A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat. Genet. 13, 399-408.
-
(1996)
Nat. Genet.
, vol.13
, pp. 399-408
-
-
Feder, J.N.1
Gnirke, A.2
Thomas, W.3
Tsuchihashi, Z.4
Ruddy, D.A.5
Basava, A.6
Dormishian, F.7
Domingo R., Jr.8
Ellis, M.C.9
Fullan, A.10
Hinton, L.M.11
Jones, N.L.12
Kimmel, B.E.13
Kronmal, G.S.14
Lauer, P.15
Lee, V.K.16
Loeb, D.B.17
Mapa, F.A.18
McClelland, E.19
Meyer, N.C.20
Mintier, G.A.21
Moeller, N.22
Moore, T.23
Morikang, E.24
Wolff, R.K.25
more..
-
3
-
-
16144368650
-
Haemochromatosis and HLA-H
-
Jouanolle, A. M., Gandon, G., Jezequel, P., Blayau, M., Campion, M. L., Yaouanq, J., Mosser, J., Fergelot, P., Chauvel, B., Bouric, P., Carn, G., Andrieux, N., Gicquel, I., Le Gall, J. Y., and David, V. (1996) Haemochromatosis and HLA-H. Nat. Genet. 14, 251-252.
-
(1996)
Nat. Genet.
, vol.14
, pp. 251-252
-
-
Jouanolle, A.M.1
Gandon, G.2
Jezequel, P.3
Blayau, M.4
Campion, M.L.5
Yaouanq, J.6
Mosser, J.7
Fergelot, P.8
Chauvel, B.9
Bouric, P.10
Carn, G.11
Andrieux, N.12
Gicquel, I.13
Le Gall, J.Y.14
David, V.15
-
4
-
-
17644434333
-
The hemochromatosis founder mutation in HLA-H disrupts beta2-microglobulin interaction and cell surface expression
-
Feder, J. N., Tsuchihashi, Z., Irrinki, A., Lee, V. K., Mapa, F. A., Morikang, E., Prass, C. E., Starnes, S. M., Wolff, R. K., Parkkila, S., Sly, W. S., and Schatzman, R. C. (1997) The hemochromatosis founder mutation in HLA-H disrupts beta2-microglobulin interaction and cell surface expression. J. Biol. Chem. 272, 14025-14028.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14025-14028
-
-
Feder, J.N.1
Tsuchihashi, Z.2
Irrinki, A.3
Lee, V.K.4
Mapa, F.A.5
Morikang, E.6
Prass, C.E.7
Starnes, S.M.8
Wolff, R.K.9
Parkkila, S.10
Sly, W.S.11
Schatzman, R.C.12
-
5
-
-
0035793856
-
An iron-regulated ferric reductase associated with the absorption of dietary iron
-
McKie, A. T., Barrow, D., Latunde-Dada, G. O., Rolfs, A., Sager, G., Mudaly, E., Mudaly, M., Richardson, C., Barlow, D., Bomford, A., Peters, T. J., Raja, K. B., Shirali, S., Hediger, M. A., Farzaneh, F., and Simpson, R. J. (2001) An iron-regulated ferric reductase associated with the absorption of dietary iron. Science 291, 1755-1759.
-
(2001)
Science
, vol.291
, pp. 1755-1759
-
-
McKie, A.T.1
Barrow, D.2
Latunde-Dada, G.O.3
Rolfs, A.4
Sager, G.5
Mudaly, E.6
Mudaly, M.7
Richardson, C.8
Barlow, D.9
Bomford, A.10
Peters, T.J.11
Raja, K.B.12
Shirali, S.13
Hediger, M.A.14
Farzaneh, F.15
Simpson, R.J.16
-
6
-
-
0034733635
-
A novel mammalian iron-regulated protein involved in intracellular iron metabolism
-
Abboud, S., and Haile, D. (2000) A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J. Biol. Chem. 275, 19906-19912.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 19906-19912
-
-
Abboud, S.1
Haile, D.2
-
7
-
-
0034677467
-
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
-
Donovan, A., Brownlie, A., Zhou, Y., Shepard, J., Pratt, S. J., Moynihan, J., Paw, B. H., Drejer, A. B., Barut, A., Zapata, A., Law, T. C., Brugnara, C., Lux, S. E., Pinkus, G. S., Pinkus, J. L., Kingsley, P. D. J., Palis, M. D., Fleming, M. D., Andrews, N. C., and Zon, L. I. (2000) Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature 403, 776-781.
-
(2000)
Nature
, vol.403
, pp. 776-781
-
-
Donovan, A.1
Brownlie, A.2
Zhou, Y.3
Shepard, J.4
Pratt, S.J.5
Moynihan, J.6
Paw, B.H.7
Drejer, A.B.8
Barut, A.9
Zapata, A.10
Law, T.C.11
Brugnara, C.12
Lux, S.E.13
Pinkus, G.S.14
Pinkus, J.L.15
Kingsley, P.D.J.16
Palis, M.D.17
Fleming, M.D.18
Andrews, N.C.19
Zon, L.I.20
more..
-
8
-
-
0033861745
-
A novel duodenal iron-regulated transporter, IREG1, implicated in the baso-lateral transfer of iron to the circulation
-
McKie, A. T., Marciani, P., Rolfs, A., Brennan, K., Wehr, K., Barrow, D., Miret, S., Bomford, A., Peters, T. J., Farzaneh, F., Hediger, M. A., Hentze, M. W., and Simpson, R. J. (2000) A novel duodenal iron-regulated transporter, IREG1, implicated in the baso-lateral transfer of iron to the circulation. Mol. Cell 5, 299-309.
-
(2000)
Mol. Cell
, vol.5
, pp. 299-309
-
-
McKie, A.T.1
Marciani, P.2
Rolfs, A.3
Brennan, K.4
Wehr, K.5
Barrow, D.6
Miret, S.7
Bomford, A.8
Peters, T.J.9
Farzaneh, F.10
Hediger, M.A.11
Hentze, M.W.12
Simpson, R.J.13
-
9
-
-
0032909207
-
Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse
-
Vulpe, C. D., Kuo, Y. M., Murphy, T. L., Cowley, L., Askwith, C., Libina, N., Gitschier, J., and Anderson, G. J. (1999) Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse. Nat. Genet. 21, 195-199.
-
(1999)
Nat. Genet.
, vol.21
, pp. 195-199
-
-
Vulpe, C.D.1
Kuo, Y.M.2
Murphy, T.L.3
Cowley, L.4
Askwith, C.5
Libina, N.6
Gitschier, J.7
Anderson, G.J.8
-
10
-
-
0032478524
-
Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor
-
Lebron, J. A., Bennett, M. J., Vaughn, D. E., Chirino, A. J., Snow, P. M., Mintier, G. A., Feder, J. N., and Bjorkman, P. J. (1998) Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor. Cell 93, 111-123.
-
(1998)
Cell
, vol.93
, pp. 111-123
-
-
Lebron, J.A.1
Bennett, M.J.2
Vaughn, D.E.3
Chirino, A.J.4
Snow, P.M.5
Mintier, G.A.6
Feder, J.N.7
Bjorkman, P.J.8
-
11
-
-
0033585129
-
The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor
-
Lebron, J. A., West, A. P., Jr., and Bjorkman, P. J. (1999) The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor. J. Mol. Biol. 294, 239-245.
-
(1999)
J. Mol. Biol.
, vol.294
, pp. 239-245
-
-
Lebron, J.A.1
West A.P., Jr.2
Bjorkman, P.J.3
-
12
-
-
0033662187
-
Binding to the transferrin receptor is required for endocytosis of HFE and regulation of iron homeostasis
-
Ramalingam, T. S., West, A. P., Jr., Lebron, J. A., Nangiana, J. S., Hogan, T. H., Enns, C. A., and Bjorkman, P. J. (2000) Binding to the transferrin receptor is required for endocytosis of HFE and regulation of iron homeostasis. Nat. Cell Biol. 2, 953-957.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 953-957
-
-
Ramalingam, T.S.1
West A.P., Jr.2
Lebron, J.A.3
Nangiana, J.S.4
Hogan, T.H.5
Enns, C.A.6
Bjorkman, P.J.7
-
13
-
-
0030755366
-
Cloning and characterization of a mammalian proton-coupled metal-ion transporter
-
Gunshin, H., Mackenzie, B., Berger, U. V., Gunshin, Y., Romero, M. F., Boron, W. F., Nussberger, S., Gollan, J. L., and Hediger, M. A. (1997) Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 388, 482-488.
-
(1997)
Nature
, vol.388
, pp. 482-488
-
-
Gunshin, H.1
Mackenzie, B.2
Berger, U.V.3
Gunshin, Y.4
Romero, M.F.5
Boron, W.F.6
Nussberger, S.7
Gollan, J.L.8
Hediger, M.A.9
-
14
-
-
0030763856
-
Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene
-
Fleming, M. D., Trenor, C. C., 3rd, Su, M. A., Foernzler, D., Beier, D. R., Dietrich, W. F., and Andrews, N. C. (1997) Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene. Nat. Genet. 16, 383-386.
-
(1997)
Nat. Genet.
, vol.16
, pp. 383-386
-
-
Fleming, M.D.1
Trenor C.C. III2
Su, M.A.3
Foernzler, D.4
Beier, D.R.5
Dietrich, W.F.6
Andrews, N.C.7
-
15
-
-
0028176811
-
Iron overload in beta 2-microglobulin-deficient mice
-
de Sousa, M., Reimao, R., Lacerda, R., Hugo, P., Kaufmann, S. H., and Porto, G. (1994) Iron overload in beta 2-microglobulin-deficient mice. Immunol. Lett. 39, 105-111.
-
(1994)
Immunol. Lett.
, vol.39
, pp. 105-111
-
-
De Sousa, M.1
Reimao, R.2
Lacerda, R.3
Hugo, P.4
Kaufmann, S.H.5
Porto, G.6
-
16
-
-
0029670047
-
beta2 knockout mice develop parenchymal iron overload: A putative role for class I genes of the major histocompatibility complex in iron metabolism
-
Rothenberg, B. E., and Voland, J. R. (1996) beta2 knockout mice develop parenchymal iron overload: A putative role for class I genes of the major histocompatibility complex in iron metabolism. Proc. Natl. Acad. Sci. USA 93, 1529-1534.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1529-1534
-
-
Rothenberg, B.E.1
Voland, J.R.2
-
17
-
-
0001376313
-
HFE gene knockout produces mouse model of hereditary hemochromatosis
-
Zhou, X. Y., Tomatsu, S., Fleming, R. E., Parkkila, S., Waheed, A., Jiang, J., Fei Y., Brunt, E. M., Ruddy, D. A., Prass, C. E., Schatzman, R. C., O'Neill, R., Britton, R. S., Bacon, B. R., and Sly, W. S. (1998) HFE gene knockout produces mouse model of hereditary hemochromatosis. Proc. Natl. Acad. Sci. USA 95, 2492-2497.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 2492-2497
-
-
Zhou, X.Y.1
Tomatsu, S.2
Fleming, R.E.3
Parkkila, S.4
Waheed, A.5
Jiang, J.6
Fei, Y.7
Brunt, E.M.8
Ruddy, D.A.9
Prass, C.E.10
Schatzman, R.C.11
O'Neill, R.12
Britton, R.S.13
Bacon, B.R.14
Sly, W.S.15
-
18
-
-
0033168767
-
The C282Y mutation causing hereditary hemochromatosis does not produce a null allele
-
Levy, J. E., Montross, L. K., Cohen, D. E., Fleming, M. D., and Andrews, N. C. (1999) The C282Y mutation causing hereditary hemochromatosis does not produce a null allele. Blood 94, 9-11.
-
(1999)
Blood
, vol.94
, pp. 9-11
-
-
Levy, J.E.1
Montross, L.K.2
Cohen, D.E.3
Fleming, M.D.4
Andrews, N.C.5
-
19
-
-
0033539556
-
Experimental hemochromatosis due to MHC class I HFE deficiency: Immune status and iron metabolism
-
Bahram, S., Gilfillan, S., Kuhn, L. C., Moret, R., Schulze, J. B., Lebeau, A., and Schumann, K. (1999) Experimental hemochromatosis due to MHC class I HFE deficiency: Immune status and iron metabolism. Proc. Natl. Acad. Sci. USA 96, 13312-13317.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13312-13317
-
-
Bahram, S.1
Gilfillan, S.2
Kuhn, L.C.3
Moret, R.4
Schulze, J.B.5
Lebeau, A.6
Schumann, K.7
-
20
-
-
0034062537
-
Genes that modify the hemochromatosis phenotype in mice
-
Levy, J. E., Montross, L. K., and Andrews, N. C. (2000) Genes that modify the hemochromatosis phenotype in mice. J. Clin. Invest. 105, 1209-1216.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1209-1216
-
-
Levy, J.E.1
Montross, L.K.2
Andrews, N.C.3
-
21
-
-
0032959574
-
Transferrin receptor is necessary for development of erythrocytes and the nervous system
-
Levy, J. E., Jin, O., Fujiwara, Y., Kuo, F., and Andrews, N. C. (1999) Transferrin receptor is necessary for development of erythrocytes and the nervous system. Nat. Genet. 21, 396-399.
-
(1999)
Nat. Genet.
, vol.21
, pp. 396-399
-
-
Levy, J.E.1
Jin, O.2
Fujiwara, Y.3
Kuo, F.4
Andrews, N.C.5
-
22
-
-
0023620236
-
The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships
-
Sweetser, D. A., Birkenmeier, E. H., Klisak, I. J., Zollman, S., Sparkes, R. S., Mohandas, T., Lusis, A. J., and Gordon, J. I. (1987) The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships. J. Biol. Chem. 262, 16060-16071.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 16060-16071
-
-
Sweetser, D.A.1
Birkenmeier, E.H.2
Klisak, I.J.3
Zollman, S.4
Sparkes, R.S.5
Mohandas, T.6
Lusis, A.J.7
Gordon, J.I.8
-
23
-
-
0032769069
-
Isolated rabbit enterocytes as a model cell system for investigations of chylomicron assembly and secretion
-
Cartwright, I. J., and Higgins, J. A. (1999) Isolated rabbit enterocytes as a model cell system for investigations of chylomicron assembly and secretion. J. Lipid Res. 40, 1357-1365.
-
(1999)
J. Lipid Res.
, vol.40
, pp. 1357-1365
-
-
Cartwright, I.J.1
Higgins, J.A.2
-
25
-
-
0015736883
-
Iron and chronic liver disease
-
Barry, M. (1973) Iron and chronic liver disease. J. R. Coll. Physicians London 8, 52-62.
-
(1973)
J. R. Coll. Physicians London
, vol.8
, pp. 52-62
-
-
Barry, M.1
-
26
-
-
0029877816
-
Transgenic mice that overexpress the human trefoil peptide pS2 have an increased resistance to intestinal damage
-
Playford, R. J., Marchbank, T., Goodlad, R. A., Chinery, R. A., Poulsom, R., and Hanby, A. M. (1996) Transgenic mice that overexpress the human trefoil peptide pS2 have an increased resistance to intestinal damage. Proc. Natl. Acad. Sci. USA 93, 2137-2142.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 2137-2142
-
-
Playford, R.J.1
Marchbank, T.2
Goodlad, R.A.3
Chinery, R.A.4
Poulsom, R.5
Hanby, A.M.6
-
27
-
-
0028557095
-
Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR
-
Zhou, L., Dey, C. R., Wert, S. E., DuVall, M. D., Frizzell, R. A., and Whitsett, J. A. (1994) Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR. Science 266, 1705-1708.
-
(1994)
Science
, vol.266
, pp. 1705-1708
-
-
Zhou, L.1
Dey, C.R.2
Wert, S.E.3
DuVall, M.D.4
Frizzell, R.A.5
Whitsett, J.A.6
-
28
-
-
0031002910
-
Immunohistochemistry of HLA-H, the protein defective in patients with hereditary hemochromatosis, reveals unique pattern of expression in gastrointestinal tract
-
Parkkila, S., Waheed, A., Britton, R. S., Feder, J. N., Tsuchihashi, Z., Schatzman, R. C., Bacon, B. R., and Sly, W. S. (1997) Immunohistochemistry of HLA-H, the protein defective in patients with hereditary hemochromatosis, reveals unique pattern of expression in gastrointestinal tract. Proc. Natl. Acad. Sci. USA 94, 2534-2539.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2534-2539
-
-
Parkkila, S.1
Waheed, A.2
Britton, R.S.3
Feder, J.N.4
Tsuchihashi, Z.5
Schatzman, R.C.6
Bacon, B.R.7
Sly, W.S.8
-
29
-
-
0029353515
-
Dissociation between tissue iron concentrations and transferrin saturation among inbred mouse strains
-
Leboeuf, R. C., Tolson, D., and Heinecke, J. W. (1995) Dissociation between tissue iron concentrations and transferrin saturation among inbred mouse strains. J. Lab. Clin. Med. 126, 128-136.
-
(1995)
J. Lab. Clin. Med.
, vol.126
, pp. 128-136
-
-
Leboeuf, R.C.1
Tolson, D.2
Heinecke, J.W.3
-
30
-
-
0035942201
-
Naturally variant autosomal and sex-linked loci determine the severity of iron overload in beta2-microglobulin-deficient mice
-
Sproule, T. J., Jazwinska, E. C., Britton, R. S., Bacon, B. R., Fleming, R. E., Sly, W. S., and Roopenian, D. C. (2001) Naturally variant autosomal and sex-linked loci determine the severity of iron overload in beta2-microglobulin-deficient mice. Proc. Natl. Acad. Sci. USA 98, 5170-5174.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 5170-5174
-
-
Sproule, T.J.1
Jazwinska, E.C.2
Britton, R.S.3
Bacon, B.R.4
Fleming, R.E.5
Sly, W.S.6
Roopenian, D.C.7
-
31
-
-
0033133666
-
Iron overload: Molecular clues to its cause
-
Kuhn, L. C. (1999) Iron overload: molecular clues to its cause. Trends Biochem. Sci. 24, 164-166.
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 164-166
-
-
Kuhn, L.C.1
-
32
-
-
13044317291
-
Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: Increased duodenal expression of the iron transporter DMT1
-
Fleming, R. E., Migas, M. C., Zhou, X., Jiang, J., Britton, R. S., Brunt, E. M., Tomatsu, S., Waheed, A., Bacon, B. R., and Sly, W. S. (1999) Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: Increased duodenal expression of the iron transporter DMT1. Proc. Natl. Acad. Sci. USA 96, 3143-3148.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3143-3148
-
-
Fleming, R.E.1
Migas, M.C.2
Zhou, X.3
Jiang, J.4
Britton, R.S.5
Brunt, E.M.6
Tomatsu, S.7
Waheed, A.8
Bacon, B.R.9
Sly, W.S.10
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