-
1
-
-
79955064557
-
Oxidative Stress and Cell Membranes in the Pathogenesis of Alzheimer's Disease
-
Axelsen, P. H., Komatsu, H., and Murray, I. V. J. (2011) Oxidative Stress and Cell Membranes in the Pathogenesis of Alzheimer's Disease Physiology 26, 54-69 10.1152/physiol.00024.2010
-
(2011)
Physiology
, vol.26
, pp. 54-69
-
-
Axelsen, P.H.1
Komatsu, H.2
Murray, I.V.J.3
-
2
-
-
8744276616
-
Amyloid Beta-Peptide(1-42) Contributes to the Oxidative Stress and Neurodegeneration Found in Alzheimer Disease Brain
-
Butterfield, D. A. and Boyd-Kimball, D. (2004) Amyloid Beta-Peptide(1-42) Contributes to the Oxidative Stress and Neurodegeneration Found in Alzheimer Disease Brain Brain Pathol. 14, 426-432 10.1111/j.1750-3639.2004.tb00087.x
-
(2004)
Brain Pathol.
, vol.14
, pp. 426-432
-
-
Butterfield, D.A.1
Boyd-Kimball, D.2
-
3
-
-
0033765735
-
Oxidative Injury in Diseases of the Central Nervous System: Focus on Alzheimer's Disease
-
Pratico, D. and Delanty, N. (2000) Oxidative Injury in Diseases of the Central Nervous System: Focus on Alzheimer's Disease Am. J. Med. 109, 577-585 10.1016/S0002-9343(00)00547-7
-
(2000)
Am. J. Med.
, vol.109
, pp. 577-585
-
-
Pratico, D.1
Delanty, N.2
-
4
-
-
0036591849
-
Lipid Peroxidation and Protein Oxidation in Alzheimer's Disease Brain: Potential Causes and Consequences Involving Amyloid Beta-Peptide-Associated Free Radical Oxidative Stress
-
Butterfield, D. A. and Lauderback, C. M. (2002) Lipid Peroxidation and Protein Oxidation in Alzheimer's Disease Brain: Potential Causes and Consequences Involving Amyloid Beta-Peptide-Associated Free Radical Oxidative Stress Free Radical Biol. Med. 32, 1050-1060 10.1016/S0891-5849(02)00794-3
-
(2002)
Free Radical Biol. Med.
, vol.32
, pp. 1050-1060
-
-
Butterfield, D.A.1
Lauderback, C.M.2
-
5
-
-
0032733691
-
The Role of Oxidative Stress in Alzheimer Disease
-
Markesbery, W. R. (1999) The Role of Oxidative Stress in Alzheimer Disease Arch. Neurol. 56, 1449-1452 10.1001/archneur.56.12.1449
-
(1999)
Arch. Neurol.
, vol.56
, pp. 1449-1452
-
-
Markesbery, W.R.1
-
6
-
-
0001052504
-
Copper Catalyzed Oxidation of Alzheimer A Beta
-
Atwood, C. S., Huang, X. D., Khatri, A., Scarpa, R. C., Kim, Y. S., Moir, R. D., Tanzi, R. E., Roher, A. E., and Bush, A. I. (2000) Copper Catalyzed Oxidation of Alzheimer A Beta Cell. Mol. Biol. 46, 777-783
-
(2000)
Cell. Mol. Biol.
, vol.46
, pp. 777-783
-
-
Atwood, C.S.1
Huang, X.D.2
Khatri, A.3
Scarpa, R.C.4
Kim, Y.S.5
Moir, R.D.6
Tanzi, R.E.7
Roher, A.E.8
Bush, A.I.9
-
7
-
-
0032613038
-
Role of Free Radicals and Metal Ions in the Pathogenesis of Alzheimer's Disease
-
Atwood, C. S., Huang, X. D., Moir, R. D., Tanzi, R. E., and Bush, A. I. (1999) Role of Free Radicals and Metal Ions in the Pathogenesis of Alzheimer's Disease Met. Ions Biol. Syst. 36, 309-364
-
(1999)
Met. Ions Biol. Syst.
, vol.36
, pp. 309-364
-
-
Atwood, C.S.1
Huang, X.D.2
Moir, R.D.3
Tanzi, R.E.4
Bush, A.I.5
-
8
-
-
84923257298
-
Pathways of Polyunsaturated Fatty Acid Utilization: Implications for Brain Function in Neuropsychiatric Health and Disease
-
Liu, J. J., Green, P., John Mann, J., Rapoport, S. I., and Sublette, M. E. (2015) Pathways of Polyunsaturated Fatty Acid Utilization: Implications for Brain Function in Neuropsychiatric Health and Disease Brain Res. 1597, 220-246 10.1016/j.brainres.2014.11.059
-
(2015)
Brain Res.
, vol.1597
, pp. 220-246
-
-
Liu, J.J.1
Green, P.2
John Mann, J.3
Rapoport, S.I.4
Sublette, M.E.5
-
9
-
-
84922479473
-
Polyunsaturated Fatty Acids and Their Metabolites in Brain Function and Disease
-
Bazinet, R. P. and Laye, S. (2014) Polyunsaturated Fatty Acids and Their Metabolites in Brain Function and Disease Nat. Rev. Neurosci. 15, 771-785 10.1038/nrn3820
-
(2014)
Nat. Rev. Neurosci.
, vol.15
, pp. 771-785
-
-
Bazinet, R.P.1
Laye, S.2
-
10
-
-
0035877699
-
Two Distinct Pathways of Formation of 4-Hydroxynonenal - Mechanisms of Nonenzymatic Transformation of the 9-and 13- Hydroperoxides of Linoleic Acid to 4-Hydroxyalkenals
-
Schneider, C., Tallman, K. A., Porter, N. A., and Brash, A. R. (2001) Two Distinct Pathways of Formation of 4-Hydroxynonenal-Mechanisms of Nonenzymatic Transformation of the 9-and 13- Hydroperoxides of Linoleic Acid to 4-Hydroxyalkenals J. Biol. Chem. 276, 20831-20838 10.1074/jbc.M101821200
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20831-20838
-
-
Schneider, C.1
Tallman, K.A.2
Porter, N.A.3
Brash, A.R.4
-
11
-
-
0035985698
-
Lipid Peroxidation in Neurodegeneration: New Insights into Alzheimer's Disease
-
Arlt, S., Beisiegel, U., and Kontush, A. (2002) Lipid Peroxidation in Neurodegeneration: New Insights into Alzheimer's Disease Curr. Opin. Lipidol. 13, 289-294 10.1097/00041433-200206000-00009
-
(2002)
Curr. Opin. Lipidol.
, vol.13
, pp. 289-294
-
-
Arlt, S.1
Beisiegel, U.2
Kontush, A.3
-
12
-
-
47049095632
-
Routes to 4-Hydroxynonenal: Fundamental Issues in the Mechanisms of Lipid Peroxidation
-
Schneider, C., Porter, N. A., and Brash, A. R. (2008) Routes to 4-Hydroxynonenal: Fundamental Issues in the Mechanisms of Lipid Peroxidation J. Biol. Chem. 283, 15539-15543 10.1074/jbc.R800001200
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 15539-15543
-
-
Schneider, C.1
Porter, N.A.2
Brash, A.R.3
-
13
-
-
0037411282
-
4-Hydroxy-2-Nonenal: A Product and Mediator of Oxidative Stress
-
Uchida, K. (2003) 4-Hydroxy-2-Nonenal: A Product and Mediator of Oxidative Stress Prog. Lipid Res. 42, 318-343 10.1016/S0163-7827(03)00014-6
-
(2003)
Prog. Lipid Res.
, vol.42
, pp. 318-343
-
-
Uchida, K.1
-
14
-
-
0036710931
-
Lipid Peroxidation in Aging Brain and Alzheimer's Disease
-
Montine, T. J., Neely, M. D., Quinn, J. F., Beal, M. F., Markesbery, W. R., Roberts, L. J., and Morrow, J. D. (2002) Lipid Peroxidation in Aging Brain and Alzheimer's Disease Free Radical Biol. Med. 33, 620-626 10.1016/S0891-5849(02)00807-9
-
(2002)
Free Radical Biol. Med.
, vol.33
, pp. 620-626
-
-
Montine, T.J.1
Neely, M.D.2
Quinn, J.F.3
Beal, M.F.4
Markesbery, W.R.5
Roberts, L.J.6
Morrow, J.D.7
-
15
-
-
0030714092
-
Elevated 4-Hydroxynonenal in Ventricular Fluid in Alzheimer's Disease
-
Lovell, M. A., Ehmann, W. D., Mattson, M. P., and Markesbery, W. R. (1997) Elevated 4-Hydroxynonenal in Ventricular Fluid in Alzheimer's Disease Neurobiol. Aging 18, 457-461 10.1016/S0197-4580(97)00108-5
-
(1997)
Neurobiol. Aging
, vol.18
, pp. 457-461
-
-
Lovell, M.A.1
Ehmann, W.D.2
Mattson, M.P.3
Markesbery, W.R.4
-
16
-
-
0031980065
-
Four-Hydroxynonenal, a Product of Lipid Peroxidation, Is Increased in the Brain in Alzheimer's Disease
-
Markesbery, W. R. and Lovell, M. A. (1998) Four-Hydroxynonenal, a Product of Lipid Peroxidation, Is Increased in the Brain in Alzheimer's Disease Neurobiol. Aging 19, 33-36 10.1016/S0197-4580(98)00009-8
-
(1998)
Neurobiol. Aging
, vol.19
, pp. 33-36
-
-
Markesbery, W.R.1
Lovell, M.A.2
-
17
-
-
33744935554
-
Increased Levels of 4-Hydroxynonenal and Acrolein, Neurotoxic Markers of Lipid Peroxidation, in the Brain in Mild Cognitive Impairment and Early Alzheimer's Disease
-
Williams, T. I., Lynn, B. C., Markesbery, W. R., and Lovell, M. A. (2006) Increased Levels of 4-Hydroxynonenal and Acrolein, Neurotoxic Markers of Lipid Peroxidation, in the Brain in Mild Cognitive Impairment and Early Alzheimer's Disease Neurobiol. Aging 27, 1094-1099 10.1016/j.neurobiolaging.2005.06.004
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 1094-1099
-
-
Williams, T.I.1
Lynn, B.C.2
Markesbery, W.R.3
Lovell, M.A.4
-
18
-
-
0031020476
-
A Role for 4-Hydroxynonenal, an Aldehydic Product of Lipid Peroxidation, in Disruption of Ion Homeostasis and Neuronal Death Induced by Amyloid Beta-Peptide
-
Mark, R. J., Lovell, M. A., Markesbery, W. R., Uchida, K., and Mattson, M. P. (1997) A Role for 4-Hydroxynonenal, an Aldehydic Product of Lipid Peroxidation, in Disruption of Ion Homeostasis and Neuronal Death Induced by Amyloid Beta-Peptide J. Neurochem. 68, 255-264 10.1046/j.1471-4159.1997.68010255.x
-
(1997)
J. Neurochem.
, vol.68
, pp. 255-264
-
-
Mark, R.J.1
Lovell, M.A.2
Markesbery, W.R.3
Uchida, K.4
Mattson, M.P.5
-
19
-
-
0030986669
-
Evidence That 4-Hydroxynonenal Mediates Oxidative Stress-Induced Neuronal Apoptosis
-
Kruman, I., BruceKeller, A. J., Bredesen, D., Waeg, G., and Mattson, M. P. (1997) Evidence That 4-Hydroxynonenal Mediates Oxidative Stress-Induced Neuronal Apoptosis J. Neurosci. 17, 5089-5100
-
(1997)
J. Neurosci.
, vol.17
, pp. 5089-5100
-
-
Kruman, I.1
BruceKeller, A.J.2
Bredesen, D.3
Waeg, G.4
Mattson, M.P.5
-
20
-
-
0030966546
-
Impairment of Glucose and Glutamate Transport and Induction of Mitochondrial Oxidative Stress and Dysfunction in Synaptosomes by Amyloid Beta-Peptide: Role of the Lipid Peroxidation Product 4-Hydroxynonenal
-
Keller, J. N., Pang, Z., Geddes, J. W., Begley, J. G., Germeyer, A., Waeg, G., and Mattson, M. P. (1997) Impairment of Glucose and Glutamate Transport and Induction of Mitochondrial Oxidative Stress and Dysfunction in Synaptosomes by Amyloid Beta-Peptide: Role of the Lipid Peroxidation Product 4-Hydroxynonenal J. Neurochem. 69, 273-284 10.1046/j.1471-4159.1997.69010273.x
-
(1997)
J. Neurochem.
, vol.69
, pp. 273-284
-
-
Keller, J.N.1
Pang, Z.2
Geddes, J.W.3
Begley, J.G.4
Germeyer, A.5
Waeg, G.6
Mattson, M.P.7
-
21
-
-
0035112495
-
Acrolein Is Increased in Alzheimer's Disease Brain and Is Toxic to Primary Hippocampal Cultures
-
Lovell, M. A., Xie, C. S., and Markesbery, W. R. (2001) Acrolein Is Increased in Alzheimer's Disease Brain and Is Toxic to Primary Hippocampal Cultures Neurobiol. Aging 22, 187-194 10.1016/S0197-4580(00)00235-9
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 187-194
-
-
Lovell, M.A.1
Xie, C.S.2
Markesbery, W.R.3
-
22
-
-
0030791446
-
4-Hydroxy-2-Nonenal Pyrrole Adducts in Human Neurodegenerative Disease
-
Montine, K. S., Kim, P. J., Olson, S. J., Markesbery, W. R., and Montine, T. J. (1997) 4-Hydroxy-2-Nonenal Pyrrole Adducts in Human Neurodegenerative Disease J. Neuropathol. Exp. Neurol. 56, 866-871 10.1097/00005072-199708000-00004
-
(1997)
J. Neuropathol. Exp. Neurol.
, vol.56
, pp. 866-871
-
-
Montine, K.S.1
Kim, P.J.2
Olson, S.J.3
Markesbery, W.R.4
Montine, T.J.5
-
23
-
-
0031028437
-
Immunohistochemical Detection of 4-Hydroxy-2-Nonenal Adducts in Alzheimer's Disease Is Associated with Inheritance of APOE4
-
Montine, K. S., Olson, V. J., Amarnath, V., Whetsell, W. O., Jr., Graham, D. G., and Montine, T. J. (1997) Immunohistochemical Detection of 4-Hydroxy-2-Nonenal Adducts in Alzheimer's Disease Is Associated With Inheritance of APOE4 Am. J. Pathol. 150, 437-443
-
(1997)
Am. J. Pathol.
, vol.150
, pp. 437-443
-
-
Montine, K.S.1
Olson, V.J.2
Amarnath, V.3
Whetsell, W.O.4
Graham, D.G.5
Montine, T.J.6
-
24
-
-
0030989545
-
4-Hydroxynonenal-Derived Advanced Lipid Peroxidation End Products Are Increased in Alzheimer's Disease
-
Sayre, L. M., Zelasko, D. A., Harris, P. L. R., Perry, G., Salomon, R. G., and Smith, M. A. (1997) 4-Hydroxynonenal-Derived Advanced Lipid Peroxidation End Products Are Increased in Alzheimer's Disease J. Neurochem. 68, 2092-2097 10.1046/j.1471-4159.1997.68052092.x
-
(1997)
J. Neurochem.
, vol.68
, pp. 2092-2097
-
-
Sayre, L.M.1
Zelasko, D.A.2
Harris, P.L.R.3
Perry, G.4
Salomon, R.G.5
Smith, M.A.6
-
25
-
-
0031981072
-
Amyloid-Beta Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress
-
Smith, M. A., Hirai, K., Hsiao, K., Pappolla, M. A., Harris, P. L. R., Siedlak, S. L., Tabaton, M., and Perry, G. (1998) Amyloid-Beta Deposition in Alzheimer Transgenic Mice Is Associated With Oxidative Stress J. Neurochem. 70, 2212-2215 10.1046/j.1471-4159.1998.70052212.x
-
(1998)
J. Neurochem.
, vol.70
, pp. 2212-2215
-
-
Smith, M.A.1
Hirai, K.2
Hsiao, K.3
Pappolla, M.A.4
Harris, P.L.R.5
Siedlak, S.L.6
Tabaton, M.7
Perry, G.8
-
26
-
-
0033836580
-
In Alzheimer's Disease, Heme Oxygenase Is Coincident with Alz50, an Epitope of Tau Induced by 4-Hydroxy-2-Nonenal Modification
-
Takeda, A., Smith, M. A., Avila, J., Nunomura, A., Siedlak, S. L., Zhu, X. W., Perry, G., and Sayre, L. M. (2000) In Alzheimer's Disease, Heme Oxygenase Is Coincident With Alz50, an Epitope of Tau Induced by 4-Hydroxy-2-Nonenal Modification J. Neurochem. 75, 1234-1241 10.1046/j.1471-4159.2000.0751234.x
-
(2000)
J. Neurochem.
, vol.75
, pp. 1234-1241
-
-
Takeda, A.1
Smith, M.A.2
Avila, J.3
Nunomura, A.4
Siedlak, S.L.5
Zhu, X.W.6
Perry, G.7
Sayre, L.M.8
-
27
-
-
0037085455
-
High Molecular Weight Neurofilament Proteins Are Physiological Substrates of Adduction by the Lipid Peroxidation Product Hydroxynonenal
-
Wataya, T., Nunomura, A., Smith, M. A., Siedlak, S. L., Harris, P. L. R., Shimohama, S., Szweda, L. I., Kaminski, M. A., Avila, J., Price, D. L., Cleveland, D. W., Sayre, L. M., and Perry, G. (2002) High Molecular Weight Neurofilament Proteins Are Physiological Substrates of Adduction by the Lipid Peroxidation Product Hydroxynonenal J. Biol. Chem. 277, 4644 10.1074/jbc.M110913200
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4644
-
-
Wataya, T.1
Nunomura, A.2
Smith, M.A.3
Siedlak, S.L.4
Harris, P.L.R.5
Shimohama, S.6
Szweda, L.I.7
Kaminski, M.A.8
Avila, J.9
Price, D.L.10
Cleveland, D.W.11
Sayre, L.M.12
Perry, G.13
-
28
-
-
0034213718
-
High-Level Neuronal Expression of A Beta(1-42) in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity Without Plaque Formation
-
Mucke, L., Masliah, E., Yu, G. Q., Mallory, M., Rockenstein, E. M., Tatsuno, G., Hu, K., Kholodenko, D., Johnson-Wood, K., and McConlogue, L. (2000) High-Level Neuronal Expression of A Beta(1-42) in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity Without Plaque Formation J. Neurosci. 20, 4050-4058
-
(2000)
J. Neurosci.
, vol.20
, pp. 4050-4058
-
-
Mucke, L.1
Masliah, E.2
Yu, G.Q.3
Mallory, M.4
Rockenstein, E.M.5
Tatsuno, G.6
Hu, K.7
Kholodenko, D.8
Johnson-Wood, K.9
McConlogue, L.10
-
29
-
-
0344672942
-
APP Processing and Synaptic Function
-
Kamenetz, F., Tomita, T., Hsieh, H., Seabrook, G., Borchelt, D., Iwatsubo, T., Sisodia, S., and Malinow, R. (2003) APP Processing and Synaptic Function Neuron 37, 925-937 10.1016/S0896-6273(03)00124-7
-
(2003)
Neuron
, vol.37
, pp. 925-937
-
-
Kamenetz, F.1
Tomita, T.2
Hsieh, H.3
Seabrook, G.4
Borchelt, D.5
Iwatsubo, T.6
Sisodia, S.7
Malinow, R.8
-
30
-
-
33846068084
-
Amyloid Precursor Protein Overexpression Depresses Excitatory Transmission Through Both Presynaptic and Postsynaptic Mechanisms
-
Ting, J. T., Kelley, B. G., Lambert, T. J., Cook, D. G., and Sullivan, J. M. (2007) Amyloid Precursor Protein Overexpression Depresses Excitatory Transmission Through Both Presynaptic and Postsynaptic Mechanisms Proc. Natl. Acad. Sci. U. S. A. 104, 353-358 10.1073/pnas.0608807104
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 353-358
-
-
Ting, J.T.1
Kelley, B.G.2
Lambert, T.J.3
Cook, D.G.4
Sullivan, J.M.5
-
31
-
-
44549087765
-
Soluble Oligomers of the Amyloid Beta-Protein Impair Synaptic Plasticity and Behavior
-
Selkoe, D. J. (2008) Soluble Oligomers of the Amyloid Beta-Protein Impair Synaptic Plasticity and Behavior Behav. Brain Res. 192, 106-113 10.1016/j.bbr.2008.02.016
-
(2008)
Behav. Brain Res.
, vol.192
, pp. 106-113
-
-
Selkoe, D.J.1
-
32
-
-
49149124343
-
Amyloid-Beta Protein Dimers Isolated Directly from Alzheimer's Brains Impair Synaptic Plasticity and Memory
-
Shankar, G. M., Li, S. M., Mehta, T. H., Garcia-Munoz, A., Shepardson, N. E., Smith, I., Brett, F. M., Farrell, M. A., Rowan, M. J., Lemere, C. A., Regan, C. M., Walsh, D. M., Sabatini, B. L., and Selkoe, D. J. (2008) Amyloid-Beta Protein Dimers Isolated Directly From Alzheimer's Brains Impair Synaptic Plasticity and Memory Nat. Med. 14, 837-842 10.1038/nm1782
-
(2008)
Nat. Med.
, vol.14
, pp. 837-842
-
-
Shankar, G.M.1
Li, S.M.2
Mehta, T.H.3
Garcia-Munoz, A.4
Shepardson, N.E.5
Smith, I.6
Brett, F.M.7
Farrell, M.A.8
Rowan, M.J.9
Lemere, C.A.10
Regan, C.M.11
Walsh, D.M.12
Sabatini, B.L.13
Selkoe, D.J.14
-
33
-
-
65249093004
-
A Role for Synaptic Zinc in Activity-Dependent A Beta Oligomer Formation and Accumulation at Excitatory Synapses
-
Deshpande, A., Kawai, H., Metherate, R., Glabe, C. G., and Busciglio, J. (2009) A Role for Synaptic Zinc in Activity-Dependent A Beta Oligomer Formation and Accumulation at Excitatory Synapses J. Neurosci. 29, 4004-4015 10.1523/JNEUROSCI.5980-08.2009
-
(2009)
J. Neurosci.
, vol.29
, pp. 4004-4015
-
-
Deshpande, A.1
Kawai, H.2
Metherate, R.3
Glabe, C.G.4
Busciglio, J.5
-
34
-
-
62649174753
-
Oligomeric Amyloid β Associates with Postsynaptic Densities and Correlates with Excitatory Synapse Loss Near Senile Plaques
-
Koffie, R. M., Meyer-Luehmann, M., Hashimoto, T., Adams, K. W., Mielke, M. L., Garcia-Alloza, M., Micheva, K. D., Smith, S. J., Kim, M. L., Lee, V. M., Hyman, B. T., and Spires-Jones, T. L. (2009) Oligomeric Amyloid β Associates With Postsynaptic Densities and Correlates With Excitatory Synapse Loss Near Senile Plaques Proc. Natl. Acad. Sci. U. S. A. 106, 4012 10.1073/pnas.0811698106
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 4012
-
-
Koffie, R.M.1
Meyer-Luehmann, M.2
Hashimoto, T.3
Adams, K.W.4
Mielke, M.L.5
Garcia-Alloza, M.6
Micheva, K.D.7
Smith, S.J.8
Kim, M.L.9
Lee, V.M.10
Hyman, B.T.11
Spires-Jones, T.L.12
-
35
-
-
80052982307
-
The Synaptic Protein Neuroligin-1 Interacts with the Amyloid B-Peptide. Is There a Role in Alzheimer's Disease?
-
Dinamarca, M. C., Weinstein, D., Monasterio, O., and Inestrosa, N. C. (2011) The Synaptic Protein Neuroligin-1 Interacts With the Amyloid B-Peptide. Is There a Role in Alzheimer's Disease? Biochemistry 50, 8127-8137 10.1021/bi201246t
-
(2011)
Biochemistry
, vol.50
, pp. 8127-8137
-
-
Dinamarca, M.C.1
Weinstein, D.2
Monasterio, O.3
Inestrosa, N.C.4
-
36
-
-
84866539183
-
Brain Excitability and Connectivity of Neuronal Assemblies in Alzheimer's Disease: From Animal Models to Human Findings
-
D'Amelio, M. and Rossini, P. M. (2012) Brain Excitability and Connectivity of Neuronal Assemblies in Alzheimer's Disease: From Animal Models to Human Findings Prog. Neurobiol. 99, 42-60 10.1016/j.pneurobio.2012.07.001
-
(2012)
Prog. Neurobiol.
, vol.99
, pp. 42-60
-
-
D'Amelio, M.1
Rossini, P.M.2
-
37
-
-
0023748491
-
Evidence for Release of Copper in the Brain - Depolarization-Induced Release of Newly Taken-Up Copper-67
-
Hartter, D. E. and Barnea, A. (1988) Evidence for Release of Copper in the Brain-Depolarization-Induced Release of Newly Taken-Up Copper-67 Synapse 2, 412-415 10.1002/syn.890020408
-
(1988)
Synapse
, vol.2
, pp. 412-415
-
-
Hartter, D.E.1
Barnea, A.2
-
38
-
-
0024362166
-
Nerve-Endings from Rat-Brain Tissue Release Copper Upon Depolarization - A Possible Role in Regulating Neuronal Excitability
-
Kardos, J., Kovacs, I., Hajos, F., Kalman, M., and Simonyi, M. (1989) Nerve-Endings From Rat-Brain Tissue Release Copper Upon Depolarization-A Possible Role in Regulating Neuronal Excitability Neurosci. Lett. 103, 139-144 10.1016/0304-3940(89)90565-X
-
(1989)
Neurosci. Lett.
, vol.103
, pp. 139-144
-
-
Kardos, J.1
Kovacs, I.2
Hajos, F.3
Kalman, M.4
Simonyi, M.5
-
39
-
-
24944570048
-
Promotion of Oxidative Lipid Membrane Damage by Amyloid Beta Proteins
-
Murray, I. V. J., Sindoni, M. E., and Axelsen, P. H. (2005) Promotion of Oxidative Lipid Membrane Damage by Amyloid Beta Proteins Biochemistry 44, 12606-12613 10.1021/bi050926p
-
(2005)
Biochemistry
, vol.44
, pp. 12606-12613
-
-
Murray, I.V.J.1
Sindoni, M.E.2
Axelsen, P.H.3
-
40
-
-
34248219460
-
Membrane Mediated Amyloidogenesis and the Promotion of Oxidative Lipid Damage by Amyloid Beta Proteins
-
Murray, I. V. J., Liu, L., Komatsu, H., Uryu, K., Xiao, G., Lawson, J. A., and Axelsen, P. H. (2007) Membrane Mediated Amyloidogenesis and the Promotion of Oxidative Lipid Damage by Amyloid Beta Proteins J. Biol. Chem. 282, 9335-9345 10.1074/jbc.M608589200
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 9335-9345
-
-
Murray, I.V.J.1
Liu, L.2
Komatsu, H.3
Uryu, K.4
Xiao, G.5
Lawson, J.A.6
Axelsen, P.H.7
-
41
-
-
0034663858
-
Accelerated Accumulation of Amyloid Beta Proteins on Oxidatively Damaged Lipid Membranes
-
Koppaka, V. and Axelsen, P. H. (2000) Accelerated Accumulation of Amyloid Beta Proteins on Oxidatively Damaged Lipid Membranes Biochemistry 39, 10011-10016 10.1021/bi000619d
-
(2000)
Biochemistry
, vol.39
, pp. 10011-10016
-
-
Koppaka, V.1
Axelsen, P.H.2
-
42
-
-
0141481004
-
Early Synergy between Aβ42 and Oxidatively Damaged Membranes in Promoting Amyloid Fibril Formation by Aβ40
-
Koppaka, V., Paul, C., Murray, I. V. J., and Axelsen, P. H. (2003) Early Synergy Between Aβ42 and Oxidatively Damaged Membranes in Promoting Amyloid Fibril Formation by Aβ40 J. Biol. Chem. 278, 36277-36284 10.1074/jbc.M301334200
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 36277-36284
-
-
Koppaka, V.1
Paul, C.2
Murray, I.V.J.3
Axelsen, P.H.4
-
43
-
-
40849126309
-
Promotion of Amyloid β Protein Misfolding and Fibrillogenesis by a Lipid Oxidation Product
-
Liu, L., Komatsu, H., Murray, I. V. J., and Axelsen, P. H. (2008) Promotion of Amyloid β Protein Misfolding and Fibrillogenesis by a Lipid Oxidation Product J. Mol. Biol. 377, 1236-1250 10.1016/j.jmb.2008.01.057
-
(2008)
J. Mol. Biol.
, vol.377
, pp. 1236-1250
-
-
Liu, L.1
Komatsu, H.2
Murray, I.V.J.3
Axelsen, P.H.4
-
44
-
-
0032238783
-
Increased F-2-Isoprostanes in Alzheimer's Disease: Evidence for Enhanced Lipid Peroxidation in Vivo
-
Pratico, D., Lee, V. M. Y., Trojanowski, J. Q., Rokach, J., and FitzGerald, G. A. (1998) Increased F-2-Isoprostanes in Alzheimer's Disease: Evidence for Enhanced Lipid Peroxidation in Vivo FASEB J. 12, 1777-1783
-
(1998)
FASEB J.
, vol.12
, pp. 1777-1783
-
-
Pratico, D.1
Lee, V.M.Y.2
Trojanowski, J.Q.3
Rokach, J.4
FitzGerald, G.A.5
-
45
-
-
0033762711
-
Increased 8,12-Iso-IPF(2 Alpha)-VI in Alzheimer's Disease: Correlation of a Noninvasive Index of Lipid Peroxidation with Disease Severity
-
Pratico, D., Clark, C. M., Lee, V. M. Y., Trojanowski, J. Q., Rokach, J., and FitzGerald, G. A. (2000) Increased 8,12-Iso-IPF(2 Alpha)-VI in Alzheimer's Disease: Correlation of a Noninvasive Index of Lipid Peroxidation With Disease Severity Ann. Neurol. 48, 809-812 10.1002/1531-8249(200011)48:5<809::AID-ANA19>3.3.CO;2-0
-
(2000)
Ann. Neurol.
, vol.48
, pp. 809-812
-
-
Pratico, D.1
Clark, C.M.2
Lee, V.M.Y.3
Trojanowski, J.Q.4
Rokach, J.5
FitzGerald, G.A.6
-
46
-
-
0035983635
-
Characterisation of Adducts of the Lipid Peroxidation Product 4-Hydroxy-2-Nonenal and Amyloid Beta-Peptides by Liquid Chromatography/Electrospray Ionisation Mass Spectrometry
-
Magni, F., Galbusera, C., Tremolada, L., Ferrarese, C., and Kienle, M. G. (2002) Characterisation of Adducts of the Lipid Peroxidation Product 4-Hydroxy-2-Nonenal and Amyloid Beta-Peptides by Liquid Chromatography/Electrospray Ionisation Mass Spectrometry Rapid Commun. Mass Spectrom. 16, 1485-1493 10.1002/rcm.743
-
(2002)
Rapid Commun. Mass Spectrom.
, vol.16
, pp. 1485-1493
-
-
Magni, F.1
Galbusera, C.2
Tremolada, L.3
Ferrarese, C.4
Kienle, M.G.5
-
47
-
-
17444435925
-
Histochemical Detection of 4-Hydroxynonenal Protein in Alzheimer Amyloid
-
Ando, Y., Brannstrom, T., Uchida, K., Nyhlin, N., Nasman, B., Suhr, O., Yamashita, T., Olsson, T., El Salhy, M., Uchino, M., and Ando, M. (1998) Histochemical Detection of 4-Hydroxynonenal Protein in Alzheimer Amyloid J. Neurol. Sci. 156, 172-176 10.1016/S0022-510X(98)00042-2
-
(1998)
J. Neurol. Sci.
, vol.156
, pp. 172-176
-
-
Ando, Y.1
Brannstrom, T.2
Uchida, K.3
Nyhlin, N.4
Nasman, B.5
Suhr, O.6
Yamashita, T.7
Olsson, T.8
El Salhy, M.9
Uchino, M.10
Ando, M.11
-
48
-
-
4544285567
-
Histochemical Accumulation of Oxidative Damage Products Is Associated with Alzheimer-Like Pathology in the Canine
-
Rofina, J. E., Singh, K., Skoumalova-Vesela, A., van Ederen, A. M., van Asten, A. J. A. M., Wilhelm, J., and Gruys, E. (2004) Histochemical Accumulation of Oxidative Damage Products Is Associated With Alzheimer-Like Pathology in the Canine Amyloid 11, 90-100 10.1080/13506120412331285779
-
(2004)
Amyloid
, vol.11
, pp. 90-100
-
-
Rofina, J.E.1
Singh, K.2
Skoumalova-Vesela, A.3
Van Ederen, A.M.4
Van Asten, A.J.A.M.5
Wilhelm, J.6
Gruys, E.7
-
49
-
-
79952480344
-
Lipid Oxidation and Modification of Amyloid-Beta (A Beta) in Vitro and in Vivo
-
Ellis, G., Fang, E., Maheshwari, M., Roltsch, E., Holcomb, L., Zimmer, D., Martinez, D., and Murray, I. V. J. (2010) Lipid Oxidation and Modification of Amyloid-Beta (A Beta) in Vitro and in Vivo J. Alzheimer's Dis. 22, 593-607 10.3233/JAD-2010-100960
-
(2010)
J. Alzheimer's Dis.
, vol.22
, pp. 593-607
-
-
Ellis, G.1
Fang, E.2
Maheshwari, M.3
Roltsch, E.4
Holcomb, L.5
Zimmer, D.6
Martinez, D.7
Murray, I.V.J.8
-
50
-
-
9744284920
-
Half-Lives of Docosahexaenoic Acid in Rat Brain Phospholipids Are Prolonged by 15 Weeks of Nutritional Deprivation of N-3 Polyunsaturated Fatty Acids
-
DeMar, J. C., Ma, K. Z., Bell, J. M., and Rapoport, S. I. (2004) Half-Lives of Docosahexaenoic Acid in Rat Brain Phospholipids Are Prolonged by 15 Weeks of Nutritional Deprivation of N-3 Polyunsaturated Fatty Acids J. Neurochem. 91, 1125-1137 10.1111/j.1471-4159.2004.02789.x
-
(2004)
J. Neurochem.
, vol.91
, pp. 1125-1137
-
-
DeMar, J.C.1
Ma, K.Z.2
Bell, J.M.3
Rapoport, S.I.4
-
51
-
-
0016197372
-
Some Shortcomings of Direct Intraventricular-Injection in Mice
-
Shaw, G. G. (1974) Some Shortcomings of Direct Intraventricular-Injection in Mice Br. J. Pharmacol. 50, 603-605 10.1111/j.1476-5381.1974.tb08596.x
-
(1974)
Br. J. Pharmacol.
, vol.50
, pp. 603-605
-
-
Shaw, G.G.1
-
52
-
-
0003081395
-
Intracerebral Injections and the Growth of Viruses in the Mouse Brain
-
Mims, C. A. (1960) Intracerebral Injections and the Growth of Viruses in the Mouse Brain Br. J. Exp. Pathol. 41, 52
-
(1960)
Br. J. Exp. Pathol.
, vol.41
, pp. 52
-
-
Mims, C.A.1
-
53
-
-
17444365094
-
Cyclooxygenase-Dependent Lipid-Modification of Brain Proteins
-
Boutaud, O., Andreasson, K. I., Zagol-Ikapitte, I., and Oates, J. (2005) Cyclooxygenase-Dependent Lipid-Modification of Brain Proteins Brain Pathol. 15, 139-142 10.1111/j.1750-3639.2005.tb00510.x
-
(2005)
Brain Pathol.
, vol.15
, pp. 139-142
-
-
Boutaud, O.1
Andreasson, K.I.2
Zagol-Ikapitte, I.3
Oates, J.4
-
54
-
-
23844500606
-
Prostaglandin H-2-Derived Adducts of Proteins Correlate with Alzheimer's Disease Severity
-
Zagol-Ikapitte, I., Masterson, T. S., Amarnath, V., Montine, T. J., Andreasson, K. I., Boutaud, O., and Oates, J. A. (2005) Prostaglandin H-2-Derived Adducts of Proteins Correlate With Alzheimer's Disease Severity J. Neurochem. 94, 1140-1145 10.1111/j.1471-4159.2005.03264.x
-
(2005)
J. Neurochem.
, vol.94
, pp. 1140-1145
-
-
Zagol-Ikapitte, I.1
Masterson, T.S.2
Amarnath, V.3
Montine, T.J.4
Andreasson, K.I.5
Boutaud, O.6
Oates, J.A.7
-
55
-
-
80052338041
-
Altered Neuroinflammatory, Arachidonic Acid Cascade and Synaptic Markers in Postmortem Alzheimer's Disease Brain
-
Rao, J. S., Rapoport, S. I., and Kim, H. W. (2011) Altered Neuroinflammatory, Arachidonic Acid Cascade and Synaptic Markers in Postmortem Alzheimer's Disease Brain Transl. Psychiatry 1, e31 10.1038/tp.2011.27
-
(2011)
Transl. Psychiatry
, vol.1
, pp. e31
-
-
Rao, J.S.1
Rapoport, S.I.2
Kim, H.W.3
-
56
-
-
0033374599
-
Cerebrospinal Fluid Lipoproteins Are More Vulnerable to Oxidation in Alzheimer's Disease and Are Neurotoxic When Oxidized Ex Vivo
-
Bassett, C. N., Neely, M. D., Sidell, K. R., Markesbery, W. R., Switt, L. L., and Montine, T. J. (1999) Cerebrospinal Fluid Lipoproteins Are More Vulnerable to Oxidation in Alzheimer's Disease and Are Neurotoxic When Oxidized Ex Vivo Lipids 34, 1273-1280 10.1007/s11745-999-0478-1
-
(1999)
Lipids
, vol.34
, pp. 1273-1280
-
-
Bassett, C.N.1
Neely, M.D.2
Sidell, K.R.3
Markesbery, W.R.4
Switt, L.L.5
Montine, T.J.6
-
57
-
-
34547149259
-
A Mechanistic Link between Oxidative Stress and Membrane Mediated Amyloidogenesis Revealed by Infrared Spectroscopy
-
Komatsu, H., Liu, L., Murray, I. V., and Axelsen, P. H. (2007) A Mechanistic Link Between Oxidative Stress and Membrane Mediated Amyloidogenesis Revealed by Infrared Spectroscopy Biochim. Biophys. Acta, Biomembr. 1768, 1913-1922 10.1016/j.bbamem.2007.05.026
-
(2007)
Biochim. Biophys. Acta, Biomembr.
, vol.1768
, pp. 1913-1922
-
-
Komatsu, H.1
Liu, L.2
Murray, I.V.3
Axelsen, P.H.4
-
58
-
-
84865127699
-
Copper and Oxidative Stress in the Pathogenesis of Alzheimer's Disease
-
Eskici, G. and Axelsen, P. H. (2012) Copper and Oxidative Stress in the Pathogenesis of Alzheimer's Disease Biochemistry 51, 6289-6311 10.1021/bi3006169
-
(2012)
Biochemistry
, vol.51
, pp. 6289-6311
-
-
Eskici, G.1
Axelsen, P.H.2
-
59
-
-
0035875690
-
Increased Lipid Peroxidation Precedes Amyloid Plaque Formation in an Animal Model of Alzheimer Amyloidosis
-
Pratico, D., Uryu, K., Leight, S., Trojanowswki, J. Q., and Lee, V. M. Y. (2001) Increased Lipid Peroxidation Precedes Amyloid Plaque Formation in an Animal Model of Alzheimer Amyloidosis J. Neurosci. 21, 4183-4187
-
(2001)
J. Neurosci.
, vol.21
, pp. 4183-4187
-
-
Pratico, D.1
Uryu, K.2
Leight, S.3
Trojanowswki, J.Q.4
Lee, V.M.Y.5
-
60
-
-
0042932786
-
Enhanced Brain Levels of 8,12-Iso-IPF(2 Alpha)-VI Differentiate AD from Frontotemporal Dementia
-
Yao, Y., Zhukareva, V., Sung, S., Clark, C. M., Rokach, J., Lee, V. M. Y., Trojanowski, J. Q., and Pratico, D. (2003) Enhanced Brain Levels of 8,12-Iso-IPF(2 Alpha)-VI Differentiate AD From Frontotemporal Dementia Neurology 61, 475-478 10.1212/01.WNL.0000070185.02546.5D
-
(2003)
Neurology
, vol.61
, pp. 475-478
-
-
Yao, Y.1
Zhukareva, V.2
Sung, S.3
Clark, C.M.4
Rokach, J.5
Lee, V.M.Y.6
Trojanowski, J.Q.7
Pratico, D.8
-
61
-
-
77953251572
-
The Neurobiology of Isoprostanes and Alzheimer's Disease
-
Pratico, D. (2010) The Neurobiology of Isoprostanes and Alzheimer's Disease Biochim. Biophys. Acta, Mol. Cell Biol. Lipids 1801, 930-933 10.1016/j.bbalip.2010.01.009
-
(2010)
Biochim. Biophys. Acta, Mol. Cell Biol. Lipids
, vol.1801
, pp. 930-933
-
-
Pratico, D.1
-
62
-
-
0036174035
-
Malondialdehyde, Superoxide Dismutase, Melatonin, Iron, Copper, and Zinc Blood Concentrations in Patients with Alzheimer Disease: Cross-Sectional Study
-
Ozcankaya, R. and Delibas, N. (2002) Malondialdehyde, Superoxide Dismutase, Melatonin, Iron, Copper, and Zinc Blood Concentrations in Patients With Alzheimer Disease: Cross-Sectional Study Croat. Med. J. 43, 28-32
-
(2002)
Croat. Med. J.
, vol.43
, pp. 28-32
-
-
Ozcankaya, R.1
Delibas, N.2
-
63
-
-
79951946224
-
Overexpression of Aldehyde Dehydrogenase-2 Attenuates Neurotoxicity Induced by 4-Hydroxynonenal in Cultured Primary Hippocampal Neurons
-
Bai, J. and Mei, Y. (2011) Overexpression of Aldehyde Dehydrogenase-2 Attenuates Neurotoxicity Induced by 4-Hydroxynonenal in Cultured Primary Hippocampal Neurons Neurotoxic. Res. 19, 412-422 10.1007/s12640-010-9183-1
-
(2011)
Neurotoxic. Res.
, vol.19
, pp. 412-422
-
-
Bai, J.1
Mei, Y.2
-
64
-
-
84873268851
-
Acrolein Induces Alzheimer's Disease-Like Pathologies in Vitro and in Vivo
-
Huang, Y. J., Jin, M. H., Pi, R. B., Zhang, J. J., Ouyang, Y., Chao, X. J., Chen, M. H., Liu, P. Q., Yu, J. C., Ramassamy, C., Dou, J., Chen, X. H., Jiang, Y. M., and Qin, J. (2013) Acrolein Induces Alzheimer's Disease-Like Pathologies in Vitro and in Vivo Toxicol. Lett. 217, 184-191 10.1016/j.toxlet.2012.12.023
-
(2013)
Toxicol. Lett.
, vol.217
, pp. 184-191
-
-
Huang, Y.J.1
Jin, M.H.2
Pi, R.B.3
Zhang, J.J.4
Ouyang, Y.5
Chao, X.J.6
Chen, M.H.7
Liu, P.Q.8
Yu, J.C.9
Ramassamy, C.10
Dou, J.11
Chen, X.H.12
Jiang, Y.M.13
Qin, J.14
-
65
-
-
35348981740
-
Lipid Peroxidation and 4-Hydroxy-2-Nonenal Formation by Copper Ion Bound to Amyloid-Beta Peptide
-
Hayashi, T., Shishido, N., Nakayama, K., Nunomura, A., Smith, M. A., Perry, G., and Nakamura, M. (2007) Lipid Peroxidation and 4-Hydroxy-2-Nonenal Formation by Copper Ion Bound to Amyloid-Beta Peptide Free Radical Biol. Med. 43, 1552-1559 10.1016/j.freeradbiomed.2007.08.013
-
(2007)
Free Radical Biol. Med.
, vol.43
, pp. 1552-1559
-
-
Hayashi, T.1
Shishido, N.2
Nakayama, K.3
Nunomura, A.4
Smith, M.A.5
Perry, G.6
Nakamura, M.7
-
66
-
-
0042170266
-
Role of 4-Hydroxynonenal in Stress-Mediated Apoptosis Signaling
-
Awasthi, Y. C., Sharma, R., Cheng, J. Z., Yang, Y., Sharma, A., Singhal, S. S., and Awasthi, S. (2003) Role of 4-Hydroxynonenal in Stress-Mediated Apoptosis Signaling Mol. Aspects Med. 24, 219-230 10.1016/S0098-2997(03)00017-7
-
(2003)
Mol. Aspects Med.
, vol.24
, pp. 219-230
-
-
Awasthi, Y.C.1
Sharma, R.2
Cheng, J.Z.3
Yang, Y.4
Sharma, A.5
Singhal, S.S.6
Awasthi, S.7
-
67
-
-
0043172460
-
Hydroxynonenal, Toxic Carbonyls, and Alzheimer Disease
-
Liu, Q., Raina, A. K., Smith, M. A., Sayre, L. M., and Perry, G. (2003) Hydroxynonenal, Toxic Carbonyls, and Alzheimer Disease Mol. Aspects Med. 24, 305-313 10.1016/S0098-2997(03)00025-6
-
(2003)
Mol. Aspects Med.
, vol.24
, pp. 305-313
-
-
Liu, Q.1
Raina, A.K.2
Smith, M.A.3
Sayre, L.M.4
Perry, G.5
-
68
-
-
0038452658
-
Changes in Intracellular Calcium and Glutathione in Astrocytes As the Primary Mechanism of Amyloid Neurotoxicity
-
Abramov, A. Y., Canevari, L., and Duchen, M. R. (2003) Changes in Intracellular Calcium and Glutathione in Astrocytes As the Primary Mechanism of Amyloid Neurotoxicity J. Neurosci. 23, 5088-5095
-
(2003)
J. Neurosci.
, vol.23
, pp. 5088-5095
-
-
Abramov, A.Y.1
Canevari, L.2
Duchen, M.R.3
-
69
-
-
67349259616
-
Reduced Glutathione Is Highly Expressed in White Matter and Neurons in the Unperturbed Mouse Brain - Implications for Oxidative Stress Associated with Neurodegeneration
-
Miller, V. M., Lawrence, D. A., Mondal, T. K., and Seegal, R. F. (2009) Reduced Glutathione Is Highly Expressed in White Matter and Neurons in the Unperturbed Mouse Brain-Implications for Oxidative Stress Associated With Neurodegeneration Brain Res. 1276, 22-30 10.1016/j.brainres.2009.04.029
-
(2009)
Brain Res.
, vol.1276
, pp. 22-30
-
-
Miller, V.M.1
Lawrence, D.A.2
Mondal, T.K.3
Seegal, R.F.4
-
70
-
-
33750899858
-
Potential Implications of Endogenous Aldehydes in Beta-Amyloid Misfolding, Oligomerization and Fibrillogenesis
-
Chen, K., Maley, J., and Yu, P. H. (2006) Potential Implications of Endogenous Aldehydes in Beta-Amyloid Misfolding, Oligomerization and Fibrillogenesis J. Neurochem. 99, 1413-1424 10.1111/j.1471-4159.2006.04181.x
-
(2006)
J. Neurochem.
, vol.99
, pp. 1413-1424
-
-
Chen, K.1
Maley, J.2
Yu, P.H.3
-
71
-
-
0034733705
-
Evidence That the B-Amyloid Plaques of Alzheimer's Disease Represent the Redox-Silencing and Entombment of Abeta by Zinc
-
Cuajungco, M. P., Goldstein, L. E., Nunomura, A., Smith, M. A., Lim, J. T., Atwood, C. S., Huang, X., Farrag, Y. W., Perry, G., and Bush, A. I. (2000) Evidence That the B-Amyloid Plaques of Alzheimer's Disease Represent the Redox-Silencing and Entombment of Abeta by Zinc J. Biol. Chem. 275, 19439-19442 10.1074/jbc.C000165200
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 19439-19442
-
-
Cuajungco, M.P.1
Goldstein, L.E.2
Nunomura, A.3
Smith, M.A.4
Lim, J.T.5
Atwood, C.S.6
Huang, X.7
Farrag, Y.W.8
Perry, G.9
Bush, A.I.10
-
72
-
-
42449100496
-
Trans-4-Hydroxy-2-Hexenal Is a Neurotoxic Product of Docosahexaenoic (22:6; N-3) Acid Oxidation
-
Long, E. K., Murphy, T. C., Leiphon, L. J., Watt, J., Morrow, J. D., Milne, G. L., Howard, J. R., and Picklo, M. J. (2008) Trans-4-Hydroxy-2-Hexenal Is a Neurotoxic Product of Docosahexaenoic (22:6; N-3) Acid Oxidation J. Neurochem. 105, 714-724 10.1111/j.1471-4159.2007.05175.x
-
(2008)
J. Neurochem.
, vol.105
, pp. 714-724
-
-
Long, E.K.1
Murphy, T.C.2
Leiphon, L.J.3
Watt, J.4
Morrow, J.D.5
Milne, G.L.6
Howard, J.R.7
Picklo, M.J.8
-
73
-
-
77953026426
-
Trans-4-Hydroxy-2-Hexenal, a Product of N-3 Fatty Acid Peroxidation: Make Some Room HNE
-
Long, E. K. and Picklo, M. J. (2010) Trans-4-Hydroxy-2-Hexenal, a Product of N-3 Fatty Acid Peroxidation: Make Some Room HNE Free Radical Biol. Med. 49, 1-8 10.1016/j.freeradbiomed.2010.03.015
-
(2010)
Free Radical Biol. Med.
, vol.49
, pp. 1-8
-
-
Long, E.K.1
Picklo, M.J.2
-
74
-
-
0038708285
-
Tangle and Neuron Numbers, but Not Amyloid Load, Predict Cognitive Status in Alzheimer's Disease
-
Giannakopoulos, P., Herrmann, F. R., Bussiere, T., Bouras, C., Kovari, E., Perl, D. P., Morrison, J. H., Gold, G., and Hof, P. R. (2003) Tangle and Neuron Numbers, but Not Amyloid Load, Predict Cognitive Status in Alzheimer's Disease Neurology 60, 1495-1500 10.1212/01.WNL.0000063311.58879.01
-
(2003)
Neurology
, vol.60
, pp. 1495-1500
-
-
Giannakopoulos, P.1
Herrmann, F.R.2
Bussiere, T.3
Bouras, C.4
Kovari, E.5
Perl, D.P.6
Morrison, J.H.7
Gold, G.8
Hof, P.R.9
-
75
-
-
37349096335
-
Clinicopathologic Correlations in a Large Alzheimer Disease Center Autopsy Cohort: Neuritic Plaques and Neurofibrillary Tangles '' Do Count '' When Staging Disease Severity
-
Nelson, P. T., Jicha, G. A., Schmitt, F. A., Liu, H., Davis, D. G., Mendiondo, M. S., Abner, E. L., and Markesbery, W. R. (2007) Clinicopathologic Correlations in a Large Alzheimer Disease Center Autopsy Cohort: Neuritic Plaques and Neurofibrillary Tangles '' Do Count '' When Staging Disease Severity J. Neuropathol. Exp. Neurol. 66, 1136-1146 10.1097/nen.0b013e31815c5efb
-
(2007)
J. Neuropathol. Exp. Neurol.
, vol.66
, pp. 1136-1146
-
-
Nelson, P.T.1
Jicha, G.A.2
Schmitt, F.A.3
Liu, H.4
Davis, D.G.5
Mendiondo, M.S.6
Abner, E.L.7
Markesbery, W.R.8
-
76
-
-
54949130109
-
Phospholipase A(2) Reduction Ameliorates Cognitive Deficits in a Mouse Model of Alzheimer's Disease
-
Sanchez-Mejia, R. O., Newman, J. W., Toh, S., Yu, G. Q., Zhou, Y. U., Halabisky, B., Cisse, M., Scearce-Levie, K., Cheng, I. H., Gan, L., Palop, J. J., Bonventre, J. V., and Mucke, L. (2008) Phospholipase A(2) Reduction Ameliorates Cognitive Deficits in a Mouse Model of Alzheimer's Disease Nat. Neurosci. 11, 1311-1318 10.1038/nn.2213
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 1311-1318
-
-
Sanchez-Mejia, R.O.1
Newman, J.W.2
Toh, S.3
Yu, G.Q.4
Zhou, Y.U.5
Halabisky, B.6
Cisse, M.7
Scearce-Levie, K.8
Cheng, I.H.9
Gan, L.10
Palop, J.J.11
Bonventre, J.V.12
Mucke, L.13
-
77
-
-
84863103124
-
A Dysregulated Endocannabinoid-Eicosanoid Network Supports Pathogenesis in a Mouse Model of Alzheimer's Disease
-
Piro, J. R., Benjamin, D. I., Duerr, J. M., Pi, Y. Q., Gonzales, C., Wood, K. M., Schwartz, J. W., Nomura, D. K., and Samad, T. A. (2012) A Dysregulated Endocannabinoid-Eicosanoid Network Supports Pathogenesis in a Mouse Model of Alzheimer's Disease Cell Rep. 1, 617-623 10.1016/j.celrep.2012.05.001
-
(2012)
Cell Rep.
, vol.1
, pp. 617-623
-
-
Piro, J.R.1
Benjamin, D.I.2
Duerr, J.M.3
Pi, Y.Q.4
Gonzales, C.5
Wood, K.M.6
Schwartz, J.W.7
Nomura, D.K.8
Samad, T.A.9
-
78
-
-
84915752782
-
Monoacylglycerol Lipase Inhibitor JZL184 Improves Behavior and Neural Properties in Ts65Dn Mice, a Model of Down Syndrome
-
Lysenko, L. V., Kim, J., Henry, C., Tyrtyshnaia, A., Kohnz, R. A., Madamba, F., Simon, G. M., Kleschevnikova, N. E., Nomura, D. K., Ezekowitz, R., and Kleschevnikov, A. M. (2014) Monoacylglycerol Lipase Inhibitor JZL184 Improves Behavior and Neural Properties in Ts65Dn Mice, a Model of Down Syndrome PLoS One 9, e114521 10.1371/journal.pone.0114521
-
(2014)
PLoS One
, vol.9
, pp. e114521
-
-
Lysenko, L.V.1
Kim, J.2
Henry, C.3
Tyrtyshnaia, A.4
Kohnz, R.A.5
Madamba, F.6
Simon, G.M.7
Kleschevnikova, N.E.8
Nomura, D.K.9
Ezekowitz, R.10
Kleschevnikov, A.M.11
-
79
-
-
0024789124
-
Lipid Peroxidation and Free Radical Scavengers in Alzheimer's Disease
-
Jeandel, C., Nicolas, M. B., Dubois, F., Nabet-Belleville, F., Penin, F., and Cuny, G. (1989) Lipid Peroxidation and Free Radical Scavengers in Alzheimer's Disease Gerontology 35, 275-282 10.1159/000213037
-
(1989)
Gerontology
, vol.35
, pp. 275-282
-
-
Jeandel, C.1
Nicolas, M.B.2
Dubois, F.3
Nabet-Belleville, F.4
Penin, F.5
Cuny, G.6
-
80
-
-
0025259422
-
Cytotoxicity and Metabolism of 4-Hydroxy-2-Nonenal and 2-Nonenal in H2O2-Resistant Cell-Lines - Do Aldehydic By-Products of Lipid-Peroxidation Contribute to Oxidative Stress
-
Spitz, D. R., Malcolm, R. R., and Roberts, R. J. (1990) Cytotoxicity and Metabolism of 4-Hydroxy-2-Nonenal and 2-Nonenal in H2O2-Resistant Cell-Lines-Do Aldehydic By-Products of Lipid-Peroxidation Contribute to Oxidative Stress Biochem. J. 267, 453-459 10.1042/bj2670453
-
(1990)
Biochem. J.
, vol.267
, pp. 453-459
-
-
Spitz, D.R.1
Malcolm, R.R.2
Roberts, R.J.3
-
81
-
-
0028089905
-
Metabolism of 4-Hydroxynonenal, A Cytotoxic Lipid-Peroxidation Product, in Ehrlich Mouse Ascites-Cells at Different Proliferation Stages
-
Grune, T., Siems, W. G., Zollner, H., and Esterbauer, H. (1994) Metabolism of 4-Hydroxynonenal, A Cytotoxic Lipid-Peroxidation Product, in Ehrlich Mouse Ascites-Cells at Different Proliferation Stages Cancer Res. 54, 5231-5235
-
(1994)
Cancer Res.
, vol.54
, pp. 5231-5235
-
-
Grune, T.1
Siems, W.G.2
Zollner, H.3
Esterbauer, H.4
-
82
-
-
0028107892
-
Identification of Metabolic Pathways of the Lipid-Peroxidation Product 4-Hydroxynonenal by Mitochondria Isolated from Rat-Kidney Cortex
-
Ullrich, O., Grune, T., Henke, W., Esterbauer, H., and Siems, W. G. (1994) Identification of Metabolic Pathways of the Lipid-Peroxidation Product 4-Hydroxynonenal by Mitochondria Isolated From Rat-Kidney Cortex FEBS Lett. 352, 84-86 10.1016/0014-5793(94)00922-8
-
(1994)
FEBS Lett.
, vol.352
, pp. 84-86
-
-
Ullrich, O.1
Grune, T.2
Henke, W.3
Esterbauer, H.4
Siems, W.G.5
-
83
-
-
0036660272
-
Elevated Glutathione As a Therapeutic Strategy in Alzheimer's Disease
-
Butterfield, D. A., Pocernich, C. B., and Drake, J. (2002) Elevated Glutathione As a Therapeutic Strategy in Alzheimer's Disease Drug Dev. Res. 56, 428-437 10.1002/ddr.10095
-
(2002)
Drug Dev. Res.
, vol.56
, pp. 428-437
-
-
Butterfield, D.A.1
Pocernich, C.B.2
Drake, J.3
-
84
-
-
77954824524
-
Mechanisms of 4-Hydroxy-2-Nonenal Induced Pro- A nd Anti-Apoptotic Signaling
-
Chaudhary, P., Sharma, R., Sharma, A., Vatsyayan, R., Yadav, S., Singhal, S. S., Rauniyar, N., Prokai, L., Awasthi, S., and Awasthi, Y. C. (2010) Mechanisms of 4-Hydroxy-2-Nonenal Induced Pro- A nd Anti-Apoptotic Signaling Biochemistry 49, 6263-6275 10.1021/bi100517x
-
(2010)
Biochemistry
, vol.49
, pp. 6263-6275
-
-
Chaudhary, P.1
Sharma, R.2
Sharma, A.3
Vatsyayan, R.4
Yadav, S.5
Singhal, S.S.6
Rauniyar, N.7
Prokai, L.8
Awasthi, S.9
Awasthi, Y.C.10
-
85
-
-
43849096294
-
Brain Oxidative Stress in a Triple-Transgenic Mouse Model of Alzheimer Disease
-
Resende, R., Moreira, P. I., Proenca, T., Deshpande, A., Busciglio, J., Pereira, C., and Oliveira, C. R. (2008) Brain Oxidative Stress in a Triple-Transgenic Mouse Model of Alzheimer Disease Free Radical Biol. Med. 44, 2051-2057 10.1016/j.freeradbiomed.2008.03.012
-
(2008)
Free Radical Biol. Med.
, vol.44
, pp. 2051-2057
-
-
Resende, R.1
Moreira, P.I.2
Proenca, T.3
Deshpande, A.4
Busciglio, J.5
Pereira, C.6
Oliveira, C.R.7
-
86
-
-
2442419100
-
Apolipoprotein E Epsilon 4 Count Affects Age at Onset of Alzheimer Disease, but Not Lifetime Susceptibility - the Cache County Study
-
Khachaturian, A. S., Corcoran, C. D., Mayer, L. S., Zandi, P. P., and Breitner, J. C. S. (2004) Apolipoprotein E Epsilon 4 Count Affects Age at Onset of Alzheimer Disease, but Not Lifetime Susceptibility-The Cache County Study Arch. Gen. Psychiatry 61, 518-524 10.1001/archpsyc.61.5.518
-
(2004)
Arch. Gen. Psychiatry
, vol.61
, pp. 518-524
-
-
Khachaturian, A.S.1
Corcoran, C.D.2
Mayer, L.S.3
Zandi, P.P.4
Breitner, J.C.S.5
-
87
-
-
0027194791
-
Gene Dose of Apolipoprotein-E Type-4 Allele and the Risk of Alzheimers-Disease in Late-Onset Families
-
Corder, E. H., Saunders, A. M., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Small, G. W., Roses, A. D., Haines, J. L., and Pericakvance, M. A. (1993) Gene Dose of Apolipoprotein-E Type-4 Allele and the Risk of Alzheimers-Disease in Late-Onset Families Science 261, 921-923 10.1126/science.8346443
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericakvance, M.A.9
-
88
-
-
0028305380
-
Protective Effect of Apolipoprotein-e Type-2 Allele for Late-Onset Alzheimer-Disease
-
Corder, E. H., Saunders, A. M., Risch, N. J., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Rimmler, J. B., Locke, P. A., Conneally, P. M., Schmader, K. E., Small, G. W., Roses, A. D., Haines, J. L., and Pericakvance, M. A. (1994) Protective Effect of Apolipoprotein-e Type-2 Allele for Late-Onset Alzheimer-Disease Nat. Genet. 7, 180-184 10.1038/ng0694-180
-
(1994)
Nat. Genet.
, vol.7
, pp. 180-184
-
-
Corder, E.H.1
Saunders, A.M.2
Risch, N.J.3
Strittmatter, W.J.4
Schmechel, D.E.5
Gaskell, P.C.6
Rimmler, J.B.7
Locke, P.A.8
Conneally, P.M.9
Schmader, K.E.10
Small, G.W.11
Roses, A.D.12
Haines, J.L.13
Pericakvance, M.A.14
-
89
-
-
0037065730
-
Apolipoprotein A-I-Milano and Apolipoprotein A-I-Paris Exhibit an Antioxidant Activity Distinct from That of Wild-Type Apolipoprotein A-I
-
Bielicki, J. K. and Oda, M. N. (2002) Apolipoprotein A-I-Milano and Apolipoprotein A-I-Paris Exhibit an Antioxidant Activity Distinct From That of Wild-Type Apolipoprotein A-I Biochemistry 41, 2089-2096 10.1021/bi011716p
-
(2002)
Biochemistry
, vol.41
, pp. 2089-2096
-
-
Bielicki, J.K.1
Oda, M.N.2
-
90
-
-
0034063728
-
A Mechanism for the Neuroprotective Effect of Apolipoprotein E: Isoform-Specific Modification by the Lipid Peroxidation Product 4-Hydroxynonenal
-
Pedersen, W. A., Chan, S. L., and Mattson, M. P. (2000) A Mechanism for the Neuroprotective Effect of Apolipoprotein E: Isoform-Specific Modification by the Lipid Peroxidation Product 4-Hydroxynonenal J. Neurochem. 74, 1426-1433 10.1046/j.1471-4159.2000.0741426.x
-
(2000)
J. Neurochem.
, vol.74
, pp. 1426-1433
-
-
Pedersen, W.A.1
Chan, S.L.2
Mattson, M.P.3
-
91
-
-
0024387711
-
Intravenous-Injection of [1-C-14] Arachidonate to Examine Regional Brain Lipid-Metabolism in Unanesthetized Rats
-
DeGeorge, J. J., Noronha, J. G., Bell, J., Robinson, P., and Rapoport, S. I. (1989) Intravenous-Injection of [1-C-14] Arachidonate to Examine Regional Brain Lipid-Metabolism in Unanesthetized Rats J. Neurosci. Res. 24, 413-423 10.1002/jnr.490240311
-
(1989)
J. Neurosci. Res.
, vol.24
, pp. 413-423
-
-
DeGeorge, J.J.1
Noronha, J.G.2
Bell, J.3
Robinson, P.4
Rapoport, S.I.5
-
92
-
-
78651283588
-
Rapid De-Esterification and Loss of Eicosapentaenoic Acid from Rat Brain Phospholipids: An Intracerebroventricular Study
-
Chen, C. T., Liu, Z., and Bazinet, R. P. (2011) Rapid De-Esterification and Loss of Eicosapentaenoic Acid From Rat Brain Phospholipids: An Intracerebroventricular Study J. Neurochem. 116, 363-373 10.1111/j.1471-4159.2010.07116.x
-
(2011)
J. Neurochem.
, vol.116
, pp. 363-373
-
-
Chen, C.T.1
Liu, Z.2
Bazinet, R.P.3
-
93
-
-
84921944691
-
Chronic Dietary N-6 PUFA Deprivation Leads to Conservation of Arachidonic Acid and More Rapid Loss of DHA in Rat Brain Phospholipids
-
Lin, L. E., Chen, C. T., Hildebrand, K. D., Liu, Z., Hopperton, K. E., and Bazinet, R. P. (2015) Chronic Dietary N-6 PUFA Deprivation Leads to Conservation of Arachidonic Acid and More Rapid Loss of DHA in Rat Brain Phospholipids J. Lipid Res. 56, 390-402 10.1194/jlr.M055590
-
(2015)
J. Lipid Res.
, vol.56
, pp. 390-402
-
-
Lin, L.E.1
Chen, C.T.2
Hildebrand, K.D.3
Liu, Z.4
Hopperton, K.E.5
Bazinet, R.P.6
|