Tuning a High Transmission Ion Guide to Prevent Gas-Phase Proton Exchange during H/D Exchange MS Analysis

Journal of the American Society for Mass Spectrometry

Volumn 27, Issue 4, 2016, Pages 662-668

  Guttman, Miklos ^a   Wales, Thomas E ^b   Whittington, Dale ^a   Engen, John R ^b   Brown, Jeffery M ^c   Lee, Kelly K ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b NORTHEASTERN UNIVERSITY   (United States)

^c WATERS CORPORATION   (United States)

Author keywords

Bimodal; Binomial; Conjoined ion guide; Deuterium exchange; Deuterium loss; Envelope broadening; Gas phase proton exchange; HDX; Intermolecular proton exchange; StepWave

Indexed keywords

BINS; DEUTERIUM; GASES; IONS; ISOTOPES; MASS SPECTROMETRY; PEPTIDES; PROTEINS; SPECTROMETRY;

BIMODAL; BINOMIAL; DEUTERIUM EXCHANGE; ENVELOPE BROADENING; ION GUIDE; PROTON EXCHANGE; STEPWAVE;

ION EXCHANGE;

DEUTERIUM; GAS; PEPTIDE; PROTON; VIRUS ENVELOPE PROTEIN;

ARTICLE; DEUTERIUM HYDROGEN EXCHANGE; ION TRANSPORT; LIMIT OF DETECTION; MASS SPECTROMETRY; T WAVE; VELOCITY; AMINO ACID SEQUENCE; CHEMISTRY; GAS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PROCEDURES; VIROLOGY;

AMINO ACID SEQUENCE; DEUTERIUM; DEUTERIUM EXCHANGE MEASUREMENT; ENV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; GASES; HIV; HIV INFECTIONS; HUMANS; MASS SPECTROMETRY; PEPTIDES; PROTONS;

EID: 84962260067     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-015-1330-8     Document Type: Article

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