CD4-induced activation in a soluble HIV-1 Env trimer

Structure

Volumn 22, Issue 7, 2014, Pages 974-984

  Guttman, Miklos ^a   Garcia, Natalie K ^a   Cupo, Albert ^b   Matsui, Tsutomu ^c   Julien, Jean Philippe ^d   Sanders, Rogier W ^b,e   Wilson, Ian A ^d   Moore, John P ^b   Lee, Kelly K ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

4 BENZOYL 1 [(4 METHOXY 1H PYRROLO[2,3 B]PYRIDIN 3 YL)OXOACETYL] 2 METHYLPIPERAZINE; CD4 ANTIGEN; GLYCAN; GLYCOPEPTIDASE; HUMAN IMMUNODEFICIENCY VIRUS 1 ENVELOP TRIMER; HUMAN IMMUNODEFICIENCY VIRUS FUSION INHIBITOR; NBD 556; UNCLASSIFIED DRUG; VIRUS PROTEIN; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41; N-(4-CHLOROPHENYL)-N'-(2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL)OXALAMIDE; OXALIC ACID DERIVATIVE; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE; PROTEIN BINDING; VIRUS ENVELOPE PROTEIN;

ARTICLE; BINDING SITE; CELL MEMBRANE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DEUTERIUM HYDROGEN EXCHANGE; ELECTRON MICROSCOPY; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROGEN BOND; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; SYNCHROTRON RADIATION; VIRUS ENVELOPE; X RAY CRYSTALLOGRAPHY; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; GLYCOSYLATION; HEK293 CELL LINE; HUMAN; METABOLISM; PHYSIOLOGY; PROCEDURES; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; SOLUBILITY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ANTIGENS, CD4; DEUTERIUM EXCHANGE MEASUREMENT; ENV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; GLYCOSYLATION; HEK293 CELLS; HIV ENVELOPE PROTEIN GP120; HIV ENVELOPE PROTEIN GP41; HIV-1; HUMANS; MASS SPECTROMETRY; MODELS, MOLECULAR; OXALATES; PIPERAZINES; PIPERIDINES; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; SOLUBILITY;

EID: 84904127504     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2014.05.001     Document Type: Article

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