ABCC8 R1420H loss-of-function variant in a southwest American Indian community: Association with increased birth weight and doubled risk of type 2 diabetes

Diabetes

Volumn 64, Issue 12, 2015, Pages 4322-4332

  Baier, Leslie J ^a   Muller, Yunhua Li ^a   Remedi, Maria Sara ^b   Traurig, Michael ^a   Piaggi, Paolo ^a   Wiessner, Gregory ^a   Huang, Ke ^a   Stacy, Alyssa ^a   Kobes, Sayuko ^a   Krakoff, Jonathan ^a   Bennett, Peter H ^a   Nelson, Robert G ^a   Knowler, William C ^a   Hanson, Robert L ^a   Nichols, Colin G ^b   Bogardus, Clifton ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM); ABCC8 PROTEIN, HUMAN; RECOMBINANT PROTEIN; SULFONYLUREA RECEPTOR;

ABCC8 GENE; ADULT; AMERICAN INDIAN; ARTICLE; BIRTH WEIGHT; BODY MASS; CONTROLLED STUDY; FEMALE; GENE; GENE FREQUENCY; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; HYPERINSULINEMIA; IN VITRO STUDY; INHERITANCE; LEAN BODY WEIGHT; LOSS OF FUNCTION MUTATION; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MISSENSE MUTATION; NON INSULIN DEPENDENT DIABETES MELLITUS; ONSET AGE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; AMINO ACID SUBSTITUTION; ANIMAL; ARIZONA; CHLOROCEBUS AETHIOPS; COS CELL LINE; DIABETES MELLITUS, TYPE 2; FETUS DEVELOPMENT; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; LONGITUDINAL STUDY; METABOLISM; MIDDLE AGED; PREGNANCY; RISK;

ADULT; AGE OF ONSET; AMINO ACID SUBSTITUTION; ANIMALS; ARIZONA; BIRTH WEIGHT; CERCOPITHECUS AETHIOPS; COS CELLS; DIABETES MELLITUS, TYPE 2; FEMALE; FETAL DEVELOPMENT; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INDIANS, NORTH AMERICAN; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; PREGNANCY; RECOMBINANT PROTEINS; RISK; SULFONYLUREA RECEPTORS;

EID: 84962168896     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db15-0459     Document Type: Article

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