메뉴 건너뛰기




Volumn 62, Issue 8, 2013, Pages 2984-2991

Strong parent-of-Origin effects in the association of kcnq1 variants with type 2 diabetes in american indians

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; POTASSIUM CHANNEL KCNQ1; HCCA2 PROTEIN, HUMAN; INSULIN; KCNQ1 PROTEIN, HUMAN; KLF14 PROTEIN, HUMAN; NERVE PROTEIN; TRANSCRIPTION FACTOR SP;

EID: 84891676958     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-1767     Document Type: Article
Times cited : (57)

References (31)
  • 1
    • 77954143522 scopus 로고    scopus 로고
    • Twelve type 2 diabetes susceptibility loci identified through large-Scale association analysis
    • MAGIC investigators GIANT Consortium
    • Voight BF, Scott LJ, Steinthorsdottir V, et al.; MAGIC investigators; GIANT Consortium. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 2010;42:579-589
    • (2010) Nat Genet , vol.42 , pp. 579-589
    • Voight, B.F.1    Scott, L.J.2    Steinthorsdottir, V.3
  • 2
    • 84868337361 scopus 로고    scopus 로고
    • Large-Scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
    • Wellcome Trust Case Control Consortium; Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) Investigators; Genetic Investigation of ANthropometric Traits (GIANT) Consortium; Asian Genetic Epidemiology Network-Type 2 Diabetes (AGEN-T2D) Consortium; South Asian Type 2 Diabetes (SAT2D) Consortium; DIAbetes Genetics Replication And Meta-Analysis (DIAGRAM) Consortium.
    • Morris AP, Voight BF, Teslovich TM, et al.; Wellcome Trust Case Control Consortium; Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) Investigators; Genetic Investigation of ANthropometric Traits (GIANT) Consortium; Asian Genetic Epidemiology Network-Type 2 Diabetes (AGEN-T2D) Consortium; South Asian Type 2 Diabetes (SAT2D) Consortium; DIAbetes Genetics Replication And Meta-Analysis (DIAGRAM) Consortium. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet 2012; 44:981-990
    • (2012) Nat Genet , vol.44 , pp. 981-990
    • Morris, A.P.1    Voight, B.F.2    Teslovich, T.M.3
  • 3
    • 50449085998 scopus 로고    scopus 로고
    • Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
    • Yasuda K, Miyake K, Horikawa Y, et al. Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat Genet 2008;40:1092-1097
    • (2008) Nat Genet , vol.40 , pp. 1092-1097
    • Yasuda, K.1    Miyake, K.2    Horikawa, Y.3
  • 4
    • 50449085212 scopus 로고    scopus 로고
    • SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in east asian and european populations
    • Unoki H, Takahashi A, Kawaguchi T, et al. SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nat Genet 2008;40:1098-1102
    • (2008) Nat Genet , vol.40 , pp. 1098-1102
    • Unoki, H.1    Takahashi, A.2    Kawaguchi, T.3
  • 5
    • 72449122779 scopus 로고    scopus 로고
    • Parental origin of sequence variants associated with complex diseases
    • DIAGRAM Consortium
    • Kong A, Steinthorsdottir V, Masson G, et al.; DIAGRAM Consortium. Parental origin of sequence variants associated with complex disease s. Nature 2009;462:868-874
    • (2009) Nature , vol.462 , pp. 868-874
    • Kong, A.1    Steinthorsdottir, V.2    Masson, G.3
  • 6
    • 0018223157 scopus 로고
    • Diabetes incidence and prevalence in pima indians: A 19-Fold greater incidence than in rochester, minnesota
    • Knowler WC, Bennett PH, Hamman RF, Miller M. Diabetes incidence and prevalence in Pima Indians: A 19-fold greater incidence than in Rochester, Minnesota. Am J Epidemiol 1978;108:497-505
    • (1978) Am J Epidemiol , vol.108 , pp. 497-505
    • Knowler, W.C.1    Bennett, P.H.2    Hamman, R.F.3    Miller, M.4
  • 7
    • 1842334456 scopus 로고    scopus 로고
    • Report of the expert committee on the diagnosis and classification of diabetes mellitus
    • American Diabetes Association Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
    • American Diabetes Association Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 1997;20: 1183-1197
    • (1997) Diabetes Care , vol.20 , pp. 1183-1197
  • 8
    • 0033645241 scopus 로고    scopus 로고
    • Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: A study of discordant sibships
    • Dabelea D, Hanson RL, Lindsay RS, et al. Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: A study of discordant sibships. Diabetes 2000;49:2208-2211
    • (2000) Diabetes , vol.49 , pp. 2208-2211
    • Dabelea, D.1    Hanson, R.L.2    Lindsay, R.S.3
  • 9
    • 0033362236 scopus 로고    scopus 로고
    • Methods for detection of parent-Of-Origin effects in genetic studies of case-parents triads
    • Weinberg CR. Methods for detection of parent-of-origin effects in genetic studies of case-parents triads. Am J Hum Genet 1999;65:229-235
    • (1999) Am J Hum Genet , vol.65 , pp. 229-235
    • Weinberg, C.R.1
  • 10
    • 34249785394 scopus 로고    scopus 로고
    • Acute insulin response is an independent predictor of type 2 diabetes mellitus in individuals with both normal fasting and 2-H plasma glucose concentrations
    • Bunt JC, Krakoff J, Ortega E, Knowler WC, Bogardus C. Acute insulin response is an independent predictor of type 2 diabetes mellitus in individuals with both normal fasting and 2-h plasma glucose concentrations. Diabetes Metab Res Rev 2007;23:304-310
    • (2007) Diabetes Metab Res Rev , vol.23 , pp. 304-310
    • Bunt, J.C.1    Krakoff, J.2    Ortega, E.3    Knowler, W.C.4    Bogardus, C.5
  • 11
    • 0027762766 scopus 로고
    • Insulin resistance and insulin secretory dysfunction as precursors of non-Insulin-Dependent diabetes mellitus. Prospective studies of pima indians
    • Lillioja S, Mott DM, Spraul M, et al. Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians. N Engl J Med 1993;329:1988-1992
    • (1993) N Engl J Med , vol.329 , pp. 1988-1992
    • Lillioja, S.1    Mott, D.M.2    Spraul, M.3
  • 12
    • 0023811760 scopus 로고
    • Obesity and insulin resistance: Lessons learned from the pima indians
    • Lillioja S, Bogardus C. Obesity and insulin resistance: lessons learned from the Pima Indians. Diabetes Metab Rev 1988;4:517-540
    • (1988) Diabetes Metab Rev , vol.4 , pp. 517-540
    • Lillioja, S.1    Bogardus, C.2
  • 13
    • 34250861441 scopus 로고    scopus 로고
    • A genomewide single-Nucleotidepolymorphism panel for mexican american admixture mapping
    • Tian C, Hinds DA, Shigeta R, et al. A genomewide single- nucleotidepolymorphism panel for Mexican American admixture mapping. Am J Hum Genet 2007;80:1014-1023
    • (2007) Am J Hum Genet , vol.80 , pp. 1014-1023
    • Tian, C.1    Hinds, D.A.2    Shigeta, R.3
  • 14
    • 0022468357 scopus 로고
    • Individual admixture estimates: Disease associations and individual risk of diabetes and gallbladder disease among mexican-Americans in starr county
    • Texas
    • Hanis CL, Chakraborty R, Ferrell RE, Schull WJ. Individual admixture estimates: Disease associations and individual risk of diabetes and gallbladder disease among Mexican-Americans in Starr County, Texas. Am J Phys Anthropol 1986;70:433-441
    • (1986) Am J Phys Anthropol , vol.70 , pp. 433-441
    • Hanis, C.L.1    Chakraborty, R.2    Ferrell, R.E.3    Schull, W.J.4
  • 15
    • 0036948344 scopus 로고    scopus 로고
    • Enhanced pedigree error detection
    • Sun L, Wilder K, McPeek MS. Enhanced pedigree error detection. Hum Hered 2002;54:99-110
    • (2002) Hum Hered , vol.54 , pp. 99-110
    • Sun, L.1    Wilder, K.2    McPeek, M.S.3
  • 16
    • 0021344005 scopus 로고
    • Easy calculations of lod scores and genetic risks on small computers
    • Lathrop GM, Lalouel JM. Easy calculations of lod scores and genetic risks on small computers. Am J Hum Genet 1984;36:460-465
    • (1984) Am J Hum Genet , vol.36 , pp. 460-465
    • Lathrop, G.M.1    Lalouel, J.M.2
  • 18
    • 28444493739 scopus 로고    scopus 로고
    • Combining probability from independent tests: The weighted Z-Method is superior to fisher's approach
    • Whitlock MC. Combining probability from independent tests: the weighted Z-method is superior to Fisher's approach. J Evol Biol 2005;18:1368-1373
    • (2005) J Evol Biol , vol.18 , pp. 1368-1373
    • Whitlock, M.C.1
  • 19
    • 33645730032 scopus 로고    scopus 로고
    • Design and analysis of genetic association studies to finely map a locus identified by linkage analysis: Sample size and power calculations
    • Hanson RL, Looker HC, Ma L, Muller YL, Baier LJ, Knowler WC. Design and analysis of genetic association studies to finely map a locus identified by linkage analysis: sample size and power calculations. Ann Hum Genet 2006;70:332-349
    • (2006) Ann Hum Genet , vol.70 , pp. 332-349
    • Hanson, R.L.1    Looker, H.C.2    Ma, L.3    Muller, Y.L.4    Baier, L.J.5    Knowler, W.C.6
  • 20
    • 79957607662 scopus 로고    scopus 로고
    • Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes
    • GIANT Consortium; MAGIC Investigators; DIAGRAM Consortium; MuTHER Consortium
    • Small KS, Hedman AK, Grundberg E, et al.; GIANT Consortium; MAGIC Investigators; DIAGRAM Consortium; MuTHER Consortium. Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes. Nat Genet 2011;43:561-564
    • (2011) Nat Genet , vol.43 , pp. 561-564
    • Small, K.S.1    Hedman, A.K.2    Grundberg, E.3
  • 21
    • 67649974089 scopus 로고    scopus 로고
    • The type 2 diabetes associatedminor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load
    • Holmkvist J, Banasik K, Andersen G, et al. The type 2 diabetes associatedminor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load. PLoS ONE 2009;4:e5872
    • (2009) PLoS ONE , vol.4
    • Holmkvist, J.1    Banasik, K.2    Andersen, G.3
  • 22
    • 67349205597 scopus 로고    scopus 로고
    • Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a chinese population
    • Hu C, Wang C, Zhang R, et al. Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population. Diabetologia 2009;52:1322-1325
    • (2009) Diabetologia , vol.52 , pp. 1322-1325
    • Hu, C.1    Wang, C.2    Zhang, R.3
  • 23
    • 70349640785 scopus 로고    scopus 로고
    • A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion
    • Jonsson A, Isomaa B, Tuomi T, et al. A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion. Diabetes 2009;58:2409-2413
    • (2009) Diabetes , vol.58 , pp. 2409-2413
    • Jonsson, A.1    Isomaa, B.2    Tuomi, T.3
  • 24
    • 67650251656 scopus 로고    scopus 로고
    • Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion
    • Müssig K, Staiger H, Machicao F, et al. Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion. Diabetes 2009;58:1715-1720
    • (2009) Diabetes , vol.58 , pp. 1715-1720
    • Müssig, K.1    Staiger, H.2    Machicao, F.3
  • 25
    • 66649101376 scopus 로고    scopus 로고
    • Genetic variation in KCNQ1 associates with fasting glucose and b-Cell function: A study of 3,734 subjects comprising three ethnicities living in singapore
    • Tan JT, Nurbaya S, Gardner D, Ye S, Tai ES, Ng DP. Genetic variation in KCNQ1 associates with fasting glucose and b-cell function: A study of 3,734 subjects comprising three ethnicities living in Singapore. Diabetes 2009;58: 1445-1449
    • (2009) Diabetes , vol.58 , pp. 1445-1449
    • Tan, J.T.1    Nurbaya, S.2    Gardner, D.3    Ye, S.4    Tai, E.S.5    Ng, D.P.6
  • 26
    • 84863046601 scopus 로고    scopus 로고
    • Replication of genome-Wide association signals of type 2 diabetes in han chinese in a prospective cohort
    • Chang YC, Chiu YF, Liu PH, et al. Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort. Clin Endocrinol (Oxf) 2012;76:365-372
    • (2012) Clin Endocrinol (Oxf) , vol.76 , pp. 365-372
    • Chang, Y.C.1    Chiu, Y.F.2    Liu, P.H.3
  • 27
    • 84857709224 scopus 로고    scopus 로고
    • Common variants in the type 2 diabetes KCNQ1 gene are associated with impairment in insulin secretion during hyperglycaemic glucose clamp
    • van Vliet-Ostaptchouk JV, van Haeften TW, Landman GW, et al. Common variants in the type 2 diabetes KCNQ1 gene are associated with impairment in insulin secretion during hyperglycaemic glucose clamp. PLoS ONE 2012;7:e32148
    • (2012) PLoS ONE , vol.7
    • Van Vliet-Ostaptchouk, J.V.1    Van Haeften, T.W.2    Landman, G.W.3
  • 28
    • 0031046285 scopus 로고    scopus 로고
    • Human KVLQT1 gene shows tissue-Specific imprinting and encompasses beckwith-Wiedemann syndrome chromosomal rearrangements
    • Lee MP, Hu RJ, Johnson LA, Feinberg AP. Human KVLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements. Nat Genet 1997;15:181-185
    • (1997) Nat Genet , vol.15 , pp. 181-185
    • Lee, M.P.1    Hu, R.J.2    Johnson, L.A.3    Feinberg, A.P.4
  • 30
    • 79961147541 scopus 로고    scopus 로고
    • The role of imprinted genes in fetal growth abnormalities
    • Piedrahita JA. The role of imprinted genes in fetal growth abnormalities. Birth Defects Res A Clin Mol Teratol 2011;91:682-692
    • (2011) Birth Defects Res A Clin Mol Teratol , vol.91 , pp. 682-692
    • Piedrahita, J.A.1
  • 31
    • 36849038409 scopus 로고    scopus 로고
    • TCF7L2 is not a major susceptibility gene for type 2 diabetes in pima indians: Analysis of 3,501 individuals
    • Guo T, Hanson RL, Traurig M, et al. TCF7L2 is not a major susceptibility gene for type 2 diabetes in Pima Indians: Analysis of 3,501 individuals. Diabetes 2007;56:3082-3088
    • (2007) Diabetes , vol.56 , pp. 3082-3088
    • Guo, T.1    Hanson, R.L.2    Traurig, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.