메뉴 건너뛰기




Volumn 30, Issue , 2016, Pages 93-101

Milk sphingomyelin improves lipid metabolism and alters gut microbiota in high fat diet-fed mice

Author keywords

Cholesterol; Gut microbiota; High fat diet; Lipid metabolism; Milk; Sphingomyelin

Indexed keywords

ABC TRANSPORTER G5; ACYL COENZYME A DESATURASE 1; ACYL COENZYME A OXIDASE; ACYL COENZYME A OXIDASE 1; APOLIPOPROTEIN A4; CHOLESTEROL; DIACYLGLYCEROL ACYLTRANSFERASE 2; FATTY ACID; FATTY ACID BINDING PROTEIN 2; GLUCOSE; INDUCIBLE DEGRADER OF THE LDL RECEPTOR; LIPID; LIVER X RECEPTOR ALPHA; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; MILK FAT; MILK SPHINGOMYELIN; MONOCYTE CHEMOTACTIC PROTEIN 1; OCCLUDIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9; PROTEIN ZO1; SERINE PROTEINASE; SPHINGOMYELIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 84962068344     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2015.12.003     Document Type: Article
Times cited : (134)

References (55)
  • 1
    • 0033754969 scopus 로고    scopus 로고
    • The role of high-fat diets and physical activity in the regulation of body weight
    • Schrauwen P., Westerterp K.R. The role of high-fat diets and physical activity in the regulation of body weight. Br J Nutr 2000, 84:417-427.
    • (2000) Br J Nutr , vol.84 , pp. 417-427
    • Schrauwen, P.1    Westerterp, K.R.2
  • 2
    • 78650535334 scopus 로고    scopus 로고
    • High-fat diet-induced obesity in animal models
    • Hariri N., Thibault L. High-fat diet-induced obesity in animal models. Nutr Res Rev 2010, 23:270-299.
    • (2010) Nutr Res Rev , vol.23 , pp. 270-299
    • Hariri, N.1    Thibault, L.2
  • 4
    • 79959271480 scopus 로고    scopus 로고
    • Role of intestinal inflammation as an early event in obesity and insulin resistance
    • Ding S., Lund P.K. Role of intestinal inflammation as an early event in obesity and insulin resistance. Curr Opin Clin Nutr Metab Care 2011, 14:328-333.
    • (2011) Curr Opin Clin Nutr Metab Care , vol.14 , pp. 328-333
    • Ding, S.1    Lund, P.K.2
  • 5
    • 33644522719 scopus 로고    scopus 로고
    • Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier
    • Neal M.D., Leaphart C., Levy R., Prince J., Billiar T.R., Watkins S., et al. Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier. J Immunol 2006, 176:3070-3079.
    • (2006) J Immunol , vol.176 , pp. 3070-3079
    • Neal, M.D.1    Leaphart, C.2    Levy, R.3    Prince, J.4    Billiar, T.R.5    Watkins, S.6
  • 7
    • 33847040759 scopus 로고    scopus 로고
    • Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis
    • Brun P., Castagliuolo I., Di Leo V., Buda A., Pinzani M., Palú G., et al. Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis. Am J Physiol Gastrointest Liver Physiol 2007, 292:G518-G525.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292 , pp. G518-G525
    • Brun, P.1    Castagliuolo, I.2    Di Leo, V.3    Buda, A.4    Pinzani, M.5    Palú, G.6
  • 8
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • Cani P.D., Bibiloni R., Knauf C., Waget A., Neyrinck A.M., Delzenne N.M., et al. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 2008, 57:1470-1481.
    • (2008) Diabetes , vol.57 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3    Waget, A.4    Neyrinck, A.M.5    Delzenne, N.M.6
  • 9
    • 78649887273 scopus 로고    scopus 로고
    • Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models
    • Murphy E.F., Cotter P.D., Healy S., Marques T.M., O'Sullivan O., Fouhy F., et al. Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models. Gut 2010, 59:1635-1642.
    • (2010) Gut , vol.59 , pp. 1635-1642
    • Murphy, E.F.1    Cotter, P.D.2    Healy, S.3    Marques, T.M.4    O'Sullivan, O.5    Fouhy, F.6
  • 10
    • 84856957894 scopus 로고    scopus 로고
    • Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
    • Henao-Mejia J., Elinav E., Jin C., Hao L., Mehal W.Z., Strowig T., et al. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature 2012, 482:179-185.
    • (2012) Nature , vol.482 , pp. 179-185
    • Henao-Mejia, J.1    Elinav, E.2    Jin, C.3    Hao, L.4    Mehal, W.Z.5    Strowig, T.6
  • 11
    • 0030898209 scopus 로고    scopus 로고
    • Plasma lipid and lipoprotein responses to dietary fat and cholesterol: a meta-analysis
    • Howell W.H., McNamara D.J., Tosca M.A., Smith B.T., Gaines J.A. Plasma lipid and lipoprotein responses to dietary fat and cholesterol: a meta-analysis. Am J Clin Nutr 1997, 65:1747-1764.
    • (1997) Am J Clin Nutr , vol.65 , pp. 1747-1764
    • Howell, W.H.1    McNamara, D.J.2    Tosca, M.A.3    Smith, B.T.4    Gaines, J.A.5
  • 12
    • 42249089547 scopus 로고    scopus 로고
    • Dietary cholesterol worsens adipose tissue macrophage accumulation and atherosclerosis in obese LDL receptor-deficient mice
    • Subramanian S., Han C.Y., Chiba T., McMillen T.S., Wang S.A., Haw A., et al. Dietary cholesterol worsens adipose tissue macrophage accumulation and atherosclerosis in obese LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol 2008, 28:685-691.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 685-691
    • Subramanian, S.1    Han, C.Y.2    Chiba, T.3    McMillen, T.S.4    Wang, S.A.5    Haw, A.6
  • 13
    • 80051826073 scopus 로고    scopus 로고
    • Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice
    • Subramanian S., Goodspeed L., Wang S., Kim J., Zeng L., Ioannou G.N., et al. Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice. J Lipid Res 2011, 52:1626-1635.
    • (2011) J Lipid Res , vol.52 , pp. 1626-1635
    • Subramanian, S.1    Goodspeed, L.2    Wang, S.3    Kim, J.4    Zeng, L.5    Ioannou, G.N.6
  • 14
    • 49649110937 scopus 로고    scopus 로고
    • Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis
    • Wouters K., van Gorp P.J., Bieghs V., Gijbels M.J., Duimel H., Lütjohann D., et al. Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis. Hepatology 2008, 48:474-486.
    • (2008) Hepatology , vol.48 , pp. 474-486
    • Wouters, K.1    van Gorp, P.J.2    Bieghs, V.3    Gijbels, M.J.4    Duimel, H.5    Lütjohann, D.6
  • 15
    • 0242661208 scopus 로고    scopus 로고
    • Egg sphingomyelin lowers the lymphatic absorption of cholesterol and alpha-tocopherol in rats
    • Noh S.K., Koo S.I. Egg sphingomyelin lowers the lymphatic absorption of cholesterol and alpha-tocopherol in rats. J Nutr 2003, 133:3571-3576.
    • (2003) J Nutr , vol.133 , pp. 3571-3576
    • Noh, S.K.1    Koo, S.I.2
  • 16
    • 4744352141 scopus 로고    scopus 로고
    • Milk sphingomyelin is more effective than egg sphingomyelin in inhibiting intestinal absorption of cholesterol and fat in rats
    • Noh S.K., Koo S.I. Milk sphingomyelin is more effective than egg sphingomyelin in inhibiting intestinal absorption of cholesterol and fat in rats. J Nutr 2004, 134:2611-2616.
    • (2004) J Nutr , vol.134 , pp. 2611-2616
    • Noh, S.K.1    Koo, S.I.2
  • 17
    • 0036202294 scopus 로고    scopus 로고
    • Dietary sphingomyelin suppresses intestinal cholesterol absorption by decreasing thermodynamic activity of cholesterol monomers
    • Eckhardt E.R., Wang D.Q., Donovan J.M., Carey M.C. Dietary sphingomyelin suppresses intestinal cholesterol absorption by decreasing thermodynamic activity of cholesterol monomers. Gastroenterology 2002, 122:948-956.
    • (2002) Gastroenterology , vol.122 , pp. 948-956
    • Eckhardt, E.R.1    Wang, D.Q.2    Donovan, J.M.3    Carey, M.C.4
  • 18
    • 33748427104 scopus 로고    scopus 로고
    • Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis in APOE*3Leiden mice
    • Duivenvoorden I., Voshol P.J., Rensen P.C., van Duyvenvoorde W., Romijn J.A., Emeis J.J., et al. Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis in APOE*3Leiden mice. Am J Clin Nutr 2006, 84:312-321.
    • (2006) Am J Clin Nutr , vol.84 , pp. 312-321
    • Duivenvoorden, I.1    Voshol, P.J.2    Rensen, P.C.3    van Duyvenvoorde, W.4    Romijn, J.A.5    Emeis, J.J.6
  • 20
    • 11244300911 scopus 로고    scopus 로고
    • Interaction of cholesterol with sphingosine: physicochemical characterization and impact on intestinal absorption
    • Garmy N., Taieb N., Yahi N., Fantini J. Interaction of cholesterol with sphingosine: physicochemical characterization and impact on intestinal absorption. J Lipid Res 2005, 46:36-45.
    • (2005) J Lipid Res , vol.46 , pp. 36-45
    • Garmy, N.1    Taieb, N.2    Yahi, N.3    Fantini, J.4
  • 23
    • 0034039623 scopus 로고    scopus 로고
    • A mutual inhibitory effect on absorption of sphingomyelin and cholesterol
    • Nyberg L., Duan R.D., Nilsson A. A mutual inhibitory effect on absorption of sphingomyelin and cholesterol. J Nutr Biochem 2000, 11:244-249.
    • (2000) J Nutr Biochem , vol.11 , pp. 244-249
    • Nyberg, L.1    Duan, R.D.2    Nilsson, A.3
  • 24
    • 0033573110 scopus 로고    scopus 로고
    • Analysis of natural and synthetic sphingomyelins using high-performance thin-layer chromatography
    • Ramstedt B., Leppimaki P., Axberg M., Slotte J.P. Analysis of natural and synthetic sphingomyelins using high-performance thin-layer chromatography. Eur J Biochem 1999, 266:997-1002.
    • (1999) Eur J Biochem , vol.266 , pp. 997-1002
    • Ramstedt, B.1    Leppimaki, P.2    Axberg, M.3    Slotte, J.P.4
  • 25
    • 0036483660 scopus 로고    scopus 로고
    • The composition of bovine milk lipids: January 1995 to December 2000
    • Jensen R.G. The composition of bovine milk lipids: January 1995 to December 2000. J Dairy Sci 2002, 85:295-350.
    • (2002) J Dairy Sci , vol.85 , pp. 295-350
    • Jensen, R.G.1
  • 26
    • 39149087033 scopus 로고    scopus 로고
    • The effect of phospholipids on milkfat crystallization behavior
    • Fedotova Y., Lencki R.W. The effect of phospholipids on milkfat crystallization behavior. J Am Oil Chem Soc 2008, 85:205-212.
    • (2008) J Am Oil Chem Soc , vol.85 , pp. 205-212
    • Fedotova, Y.1    Lencki, R.W.2
  • 28
    • 84927626701 scopus 로고    scopus 로고
    • Anthocyanin-rich black elderberry extract improves markers of HDL function and reduces aortic cholesterol in hyperlipidemic mice
    • Farrell N., Norris G., Lee S.G., Chun O.K., Blesso C.N. Anthocyanin-rich black elderberry extract improves markers of HDL function and reduces aortic cholesterol in hyperlipidemic mice. Food Funct 2015, 6:1278-1287.
    • (2015) Food Funct , vol.6 , pp. 1278-1287
    • Farrell, N.1    Norris, G.2    Lee, S.G.3    Chun, O.K.4    Blesso, C.N.5
  • 29
    • 84863981120 scopus 로고    scopus 로고
    • Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms
    • Caporaso J.G., Lauber C.L., Walters W.A., Berg-Lyons D., Huntley J., Fierer N., et al. Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms. ISME J 2012, 6:1621-1624.
    • (2012) ISME J , vol.6 , pp. 1621-1624
    • Caporaso, J.G.1    Lauber, C.L.2    Walters, W.A.3    Berg-Lyons, D.4    Huntley, J.5    Fierer, N.6
  • 30
    • 84899531657 scopus 로고    scopus 로고
    • Analysis, optimization and verification of Illumina-generated 16S rRNA gene amplicon surveys
    • Nelson M.C., Morrison H.G., Benjamino J., Grim S.L., Graf J. Analysis, optimization and verification of Illumina-generated 16S rRNA gene amplicon surveys. PLoS One 2014, 9.
    • (2014) PLoS One , vol.9
    • Nelson, M.C.1    Morrison, H.G.2    Benjamino, J.3    Grim, S.L.4    Graf, J.5
  • 31
    • 79952768966 scopus 로고    scopus 로고
    • Membrane sphingolipids as essential molecular signals for Bacteroides survival in the intestine
    • An D., Na C., Bielawski J., Hannun Y.A., Kasper D.L. Membrane sphingolipids as essential molecular signals for Bacteroides survival in the intestine. Proc Natl Acad Sci U S A 2011, 108(Suppl. 1):4666-4671.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 4666-4671
    • An, D.1    Na, C.2    Bielawski, J.3    Hannun, Y.A.4    Kasper, D.L.5
  • 32
    • 34047269605 scopus 로고    scopus 로고
    • Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat
    • Sampath H., Miyazaki M., Dobrzyn A., Ntambi J.M. Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat. J Biol Chem 2007, 282:2483-2493.
    • (2007) J Biol Chem , vol.282 , pp. 2483-2493
    • Sampath, H.1    Miyazaki, M.2    Dobrzyn, A.3    Ntambi, J.M.4
  • 33
    • 84942792026 scopus 로고    scopus 로고
    • Influence of high-fat diet on gut microbiota: a driving force for chronic disease risk
    • Murphy E.A., Velazquez K.T., Herbert K.M. Influence of high-fat diet on gut microbiota: a driving force for chronic disease risk. Curr Opin Clin Nutr Metab Care 2015, 18:515-520.
    • (2015) Curr Opin Clin Nutr Metab Care , vol.18 , pp. 515-520
    • Murphy, E.A.1    Velazquez, K.T.2    Herbert, K.M.3
  • 34
    • 0029744263 scopus 로고    scopus 로고
    • Distribution of alkaline sphingomyelinase activity in human beings and animals. Tissue and species differences
    • Duan R.D., Hertervig E., Nyberg L., Hauge T., Sternby B., Lillienau J., et al. Distribution of alkaline sphingomyelinase activity in human beings and animals. Tissue and species differences. Dig Dis Sci 1996, 41:1801-1806.
    • (1996) Dig Dis Sci , vol.41 , pp. 1801-1806
    • Duan, R.D.1    Hertervig, E.2    Nyberg, L.3    Hauge, T.4    Sternby, B.5    Lillienau, J.6
  • 35
    • 0035999526 scopus 로고    scopus 로고
    • In vitro effects of fat, FA, and cholesterol on sphingomyelin hydrolysis induced by rat intestinal alkaline sphingomyelinase
    • Liu J.J., Nilsson A., Duan R.D. In vitro effects of fat, FA, and cholesterol on sphingomyelin hydrolysis induced by rat intestinal alkaline sphingomyelinase. Lipids 2002, 37:469-474.
    • (2002) Lipids , vol.37 , pp. 469-474
    • Liu, J.J.1    Nilsson, A.2    Duan, R.D.3
  • 36
    • 78649327270 scopus 로고    scopus 로고
    • Generating ceramide from sphingomyelin by alkaline sphingomyelinase in the gut enhances sphingomyelin-induced inhibition of cholesterol uptake in Caco-2 cells
    • Feng D., Ohlsson L., Ling W., Nilsson A., Duan R.D. Generating ceramide from sphingomyelin by alkaline sphingomyelinase in the gut enhances sphingomyelin-induced inhibition of cholesterol uptake in Caco-2 cells. Dig Dis Sci 2010, 55:3377-3383.
    • (2010) Dig Dis Sci , vol.55 , pp. 3377-3383
    • Feng, D.1    Ohlsson, L.2    Ling, W.3    Nilsson, A.4    Duan, R.D.5
  • 39
    • 22744441951 scopus 로고    scopus 로고
    • Apical uptake and transepithelial transport of sphingosine monomers through intact human intestinal epithelial cells: physicochemical and molecular modeling studies
    • Garmy N., Taieb N., Yahi N., Fantini J. Apical uptake and transepithelial transport of sphingosine monomers through intact human intestinal epithelial cells: physicochemical and molecular modeling studies. Arch Biochem Biophys 2005, 440:91-100.
    • (2005) Arch Biochem Biophys , vol.440 , pp. 91-100
    • Garmy, N.1    Taieb, N.2    Yahi, N.3    Fantini, J.4
  • 40
    • 84873606795 scopus 로고    scopus 로고
    • Dietary sphingomyelin lowers hepatic lipid levels and inhibits intestinal cholesterol absorption in high-fat-fed mice
    • Chung R.W., Kamili A., Tandy S., Weir J.M., Gaire R., Wong G., et al. Dietary sphingomyelin lowers hepatic lipid levels and inhibits intestinal cholesterol absorption in high-fat-fed mice. PLoS One 2013, 8.
    • (2013) PLoS One , vol.8
    • Chung, R.W.1    Kamili, A.2    Tandy, S.3    Weir, J.M.4    Gaire, R.5    Wong, G.6
  • 41
    • 21844436528 scopus 로고    scopus 로고
    • The effect of dietary sphingolipids on plasma sphingomyelin metabolism and atherosclerosis
    • Li Z., Basterr M.J., Hailemariam T.K., Hojjati M.R., Lu S., Liu J., et al. The effect of dietary sphingolipids on plasma sphingomyelin metabolism and atherosclerosis. Biochim Biophys Acta 2005, 1735:130-134.
    • (2005) Biochim Biophys Acta , vol.1735 , pp. 130-134
    • Li, Z.1    Basterr, M.J.2    Hailemariam, T.K.3    Hojjati, M.R.4    Lu, S.5    Liu, J.6
  • 42
    • 84883562737 scopus 로고    scopus 로고
    • Effect of dietary sphingomyelin on absorption and fractional synthetic rate of cholesterol and serum lipid profile in humans
    • Ramprasath V.R., Jones P.J., Buckley D.D., Woollett L.A., Heubi J.E. Effect of dietary sphingomyelin on absorption and fractional synthetic rate of cholesterol and serum lipid profile in humans. Lipids Health Dis 2013, 12:125.
    • (2013) Lipids Health Dis , vol.12 , pp. 125
    • Ramprasath, V.R.1    Jones, P.J.2    Buckley, D.D.3    Woollett, L.A.4    Heubi, J.E.5
  • 43
    • 33846173940 scopus 로고    scopus 로고
    • Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: Role of sterol regulatory element binding protein 2
    • Alrefai W.A., Annaba F., Sarwar Z., Dwivedi A., Saksena S., Singla A., et al. Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: Role of sterol regulatory element binding protein 2. Am J Physiol Gastrointest Liver Physiol 2007, 292:G369-G376.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292 , pp. G369-G376
    • Alrefai, W.A.1    Annaba, F.2    Sarwar, Z.3    Dwivedi, A.4    Saksena, S.5    Singla, A.6
  • 44
    • 17744390348 scopus 로고    scopus 로고
    • Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters
    • Berge K.E., Tian H., Graf G.A., Yu L., Grishin N.V., Schultz J., et al. Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science 2000, 290:1771-1775.
    • (2000) Science , vol.290 , pp. 1771-1775
    • Berge, K.E.1    Tian, H.2    Graf, G.A.3    Yu, L.4    Grishin, N.V.5    Schultz, J.6
  • 45
    • 84867346639 scopus 로고    scopus 로고
    • Inhibition of intestinal cholesterol absorption decreases atherosclerosis but not adipose tissue inflammation
    • Umemoto T., Subramanian S., Ding Y., Goodspeed L., Wang S., Han C.Y., et al. Inhibition of intestinal cholesterol absorption decreases atherosclerosis but not adipose tissue inflammation. J Lipid Res 2012, 53:2380-2389.
    • (2012) J Lipid Res , vol.53 , pp. 2380-2389
    • Umemoto, T.1    Subramanian, S.2    Ding, Y.3    Goodspeed, L.4    Wang, S.5    Han, C.Y.6
  • 46
    • 0032486267 scopus 로고    scopus 로고
    • Myocyte enhancer factor 2 (MEF2)-binding site is required for GLUT4 gene expression in transgenic mice. Regulation of MEF2 DNA binding activity in insulin-deficient diabetes
    • Thai M.V., Guruswamy S., Cao K.T., Pessin J.E., Olson A.L. Myocyte enhancer factor 2 (MEF2)-binding site is required for GLUT4 gene expression in transgenic mice. Regulation of MEF2 DNA binding activity in insulin-deficient diabetes. J Biol Chem 1998, 273:14285-14292.
    • (1998) J Biol Chem , vol.273 , pp. 14285-14292
    • Thai, M.V.1    Guruswamy, S.2    Cao, K.T.3    Pessin, J.E.4    Olson, A.L.5
  • 47
    • 0038810035 scopus 로고    scopus 로고
    • An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle
    • Handschin C., Rhee J., Lin J., Tarr P.T., Spiegelman B.M. An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle. Proc Natl Acad Sci U S A 2003, 100:7111-7116.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 7111-7116
    • Handschin, C.1    Rhee, J.2    Lin, J.3    Tarr, P.T.4    Spiegelman, B.M.5
  • 49
    • 84857729398 scopus 로고    scopus 로고
    • Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota
    • Serino M., Luche E., Gres S., Baylac A., Berge M., Cenac C., et al. Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota. Gut 2012, 61:543-553.
    • (2012) Gut , vol.61 , pp. 543-553
    • Serino, M.1    Luche, E.2    Gres, S.3    Baylac, A.4    Berge, M.5    Cenac, C.6
  • 50
    • 34848912627 scopus 로고    scopus 로고
    • Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia
    • Cani P.D., Neyrinck A.M., Fava F., Knauf C., Burcelin R.G., Tuohy K.M., et al. Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia. Diabetologia 2007, 50:2374-2383.
    • (2007) Diabetologia , vol.50 , pp. 2374-2383
    • Cani, P.D.1    Neyrinck, A.M.2    Fava, F.3    Knauf, C.4    Burcelin, R.G.5    Tuohy, K.M.6
  • 51
    • 0033762339 scopus 로고    scopus 로고
    • Bifidobacterium strains from resident infant human gastrointestinal microflora exert antimicrobial activity
    • Lievin V., Peiffer I., Hudault S., Rochat F., Brassart D., Neeser J.R., et al. Bifidobacterium strains from resident infant human gastrointestinal microflora exert antimicrobial activity. Gut 2000, 47:646-652.
    • (2000) Gut , vol.47 , pp. 646-652
    • Lievin, V.1    Peiffer, I.2    Hudault, S.3    Rochat, F.4    Brassart, D.5    Neeser, J.R.6
  • 52
    • 0036085124 scopus 로고    scopus 로고
    • Gastrointestinal effects of prebiotics
    • Cummings J.H., Macfarlane G.T. Gastrointestinal effects of prebiotics. Br J Nutr 2002, 87(Suppl. 2):S145-S151.
    • (2002) Br J Nutr , vol.87 , pp. S145-S151
    • Cummings, J.H.1    Macfarlane, G.T.2
  • 53
    • 84864395103 scopus 로고    scopus 로고
    • Bacteroides uniformis CECT 7771 ameliorates metabolic and immunological dysfunction in mice with high-fat-diet induced obesity
    • Gauffin Cano P., Santacruz A., Moya A., Sanz Y. Bacteroides uniformis CECT 7771 ameliorates metabolic and immunological dysfunction in mice with high-fat-diet induced obesity. PLoS One 2012, 7.
    • (2012) PLoS One , vol.7
    • Gauffin Cano, P.1    Santacruz, A.2    Moya, A.3    Sanz, Y.4
  • 54
    • 67349234092 scopus 로고    scopus 로고
    • Dietary phospholipid-rich dairy milk extract reduces hepatomegaly, hepatic steatosis and hyperlipidemia in mice fed a high-fat diet
    • Wat E., Tandy S., Kapera E., Kamili A., Chung R.W., Brown A., et al. Dietary phospholipid-rich dairy milk extract reduces hepatomegaly, hepatic steatosis and hyperlipidemia in mice fed a high-fat diet. Atherosclerosis 2009, 205:144-150.
    • (2009) Atherosclerosis , vol.205 , pp. 144-150
    • Wat, E.1    Tandy, S.2    Kapera, E.3    Kamili, A.4    Chung, R.W.5    Brown, A.6
  • 55
    • 84872265525 scopus 로고    scopus 로고
    • Dietary fat composition influences tissue lipid profile and gene expression in Fischer-344 rats
    • Zhou A.L., Hintze K.J., Jimenez-Flores R., Ward R.E. Dietary fat composition influences tissue lipid profile and gene expression in Fischer-344 rats. Lipids 2012, 47:1119-1130.
    • (2012) Lipids , vol.47 , pp. 1119-1130
    • Zhou, A.L.1    Hintze, K.J.2    Jimenez-Flores, R.3    Ward, R.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.