Divergent associations of height with cardiometabolic disease and cancer: Epidemiology, pathophysiology, and global implications

The Lancet Diabetes and Endocrinology

Volumn 4, Issue 5, 2016, Pages 457-467

  Stefan, Norbert ^a,b,c   Häring, Hans Ulrich ^a,b,c   Hu, Frank B ^d,e   Schulze, Matthias B ^c,f  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE RECEPTOR; LACTIC ACID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; TRIACYLGLYCEROL;

AORTA ANEURYSM; BLADDER CANCER; BODY HEIGHT; BODY MASS; BREAST CANCER; CANCER INCIDENCE; CANCER RISK; CARDIOVASCULAR DISEASE; CAUSE OF DEATH; CEREBROVASCULAR ACCIDENT; CHOLESTEROL BLOOD LEVEL; COHORT ANALYSIS; COLON CANCER; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; ENDOMETRIUM CANCER; FAT MASS; GHR GENE; HEART INFARCTION; HUMAN; ISCHEMIC HEART DISEASE; KIDNEY CANCER; LCT GENE; LEUKEMIA; LUNG EMBOLISM; MACRONUTRIENT; MELANOMA; METABOLIC DISORDER; MORTALITY; NEOPLASM; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHODGKIN LYMPHOMA; NONHUMAN; OBESITY; OVARY CANCER; PATHOPHYSIOLOGY; PREGNANCY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROSTATE CANCER; RECTUM CANCER; REVIEW; SIGNAL TRANSDUCTION; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; WAIST CIRCUMFERENCE; ADMINISTRATION AND DOSAGE; ANIMAL; INCIDENCE; PROTEIN INTAKE;

ANIMALS; BODY HEIGHT; CARDIOVASCULAR DISEASES; DIABETES MELLITUS, TYPE 2; DIETARY PROTEINS; HUMANS; INCIDENCE; NEOPLASMS;

EID: 84962062327     PISSN: 22138587     EISSN: 22138595     Source Type: Journal    
DOI: 10.1016/S2213-8587(15)00474-X     Document Type: Review

References (119)

1. Bauer UE, Briss PA, Goodman RA, Bowman BA Prevention of chronic disease in the 21st century: elimination of the leading preventable causes of premature death and disability in the USA. Lancet 2014, 384:45-52.
2. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 2015, 385:117-171. GBD 2013 Mortality and Causes of Death Collaborators.
3. Després JP, Lemieux I Abdominal obesity and metabolic syndrome. Nature 2006, 444:881-887.
4. Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis. Int J Epidemiol 2012, 41:1419-1433. Emerging Risk Factors Collaboration.
5. Gunnell D, Whitley E, Upton MN, McConnachie A, Smith GD, Watt GC Associations of height, leg length, and lung function with cardiovascular risk factors in the Midspan Family Study. J Epidemiol Community Health 2003, 57:141-146.
6. Finigan J, Greenfield DM, Blumsohn A, et al. Risk factors for vertebral and nonvertebral fracture over 10 years: a population-based study in women. J Bone Miner Res 2008, 23:75-85.
7. Visscher PM, Medland SE, Ferreira MA, et al. Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings. PLoS Genet 2006, 2:e41.
8. Horikoshi M, Yaghootkar H, Mook-Kanamori DO, et al. New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nat Genet 2013, 45:76-82. the Meta-Analyses of Glucose- and Insulin-related traits Consortium (MAGIC), the Early Growth Genetics (EGG) Consortiumthe Early Growth Genetics (EGG) Consortium.
9. Wood AR, Esko T, Yang J, et al. Defining the role of common variation in the genomic and biological architecture of adult human height. Nat Genet 2014, 46:1173-1186. the Electronic Medical Records and Genomics (eMEMERGEGE) Consortium, the MIGen Consortiumthe MIGen Consortium, the PAGEGE Consortiumthe PAGEGE Consortium, the LifeLines Cohort Studythe LifeLines Cohort Study.
10. Hatton TJ, Bray BE Long run trends in the heights of European men, 19th-20th centuries. Econ Hum Biol 2010, 8:405-413.
11. Komlos J, Lauderdale BE The mysterious trend in American heights in the 20th century. Ann Hum Biol 2007, 34:206-215.
12. Chen TJ, Ji CY Secular changes of stature in rural children and adolescents in China, 1985-2010. Biomed Environ Sci 2014, 27:573-581.
13. Grasgruber P, Cacek J, Kalina T, Sebera M The role of nutrition and genetics as key determinants of the positive height trend. Econ Hum Biol 2014, 15:81-100.
14. Ji CY, Chen TJ Secular changes in stature and body mass index for Chinese youth in sixteen major cities, 1950s-2005. Am J Hum Biol 2008, 20:530-537.
15. Mamidi RS, Kulkarni B, Singh A Secular trends in height in different states of India in relation to socioeconomic characteristics and dietary intakes. Food Nutr Bull 2011, 32:23-34.
16. Hunter DJ, Reddy KS Noncommunicable diseases. N Engl J Med 2013, 369:1336-1343.
17. Hu FB, Willett WC, Li T, Stampfer MJ, Colditz GA, Manson JE Adiposity as compared with physical activity in predicting mortality among women. N Engl J Med 2004, 351:2694-2703.
18. Pischon T, Boeing H, Hoffmann K, et al. General and abdominal adiposity and risk of death in Europe. N Engl J Med 2008, 359:2105-2120.
19. Batty GD, Barzi F, Woodward M, et al. Adult height and cancer mortality in Asia: the Asia Pacific Cohort Studies Collaboration. Ann Oncol 2010, 21:646-654. the Asia Pacific Cohort Studies Collaboration.
20. Lau B, Cole SR, Gange SJ Competing risk regression models for epidemiologic data. Am J Epidemiol 2009, 170:244-256.
21. Lunn M, McNeil D Applying Cox regression to competing risks. Biometrics 1995, 51:524-532.
22. Baer HJ, Glynn RJ, Hu FB, et al. Risk factors for mortality in the nurses' health study: a competing risks analysis. Am J Epidemiol 2011, 173:319-329.
23. Wannamethee SG, Shaper AG, Lennon L, Whincup PH Height loss in older men-associations with total mortality and incidence of cardiovascular disease. Arch Intern Med 2006, 166:2546-2552.
24. Paajanen TA, Oksala NK, Kuukasjärvi P, Karhunen PJ Short stature is associated with coronary heart disease: a systematic review of the literature and a meta-analysis. Eur Heart J 2010, 31:1802-1809.
25. Schmidt M, Bøtker HE, Pedersen L, Sørensen HT Adult height and risk of ischemic heart disease, atrial fibrillation, stroke, venous thromboembolism, and premature death: a population based 36-year follow-up study. Eur J Epidemiol 2014, 29:111-118.
26. Lee CM, Barzi F, Woodward M, et al. Adult height and the risks of cardiovascular disease and major causes of death in the Asia-Pacific region: 21,000 deaths in 510,000 men and women. Int J Epidemiol 2009, 38:1060-1071. the Asia Pacific Cohort Studies Collaboration.
27. McCarron P, Okasha M, McEwen J, Smith GD Height in young adulthood and risk of death from cardiorespiratory disease: a prospective study of male former students of Glasgow University, Scotland. Am J Epidemiol 2002, 155:683-687.
28. Janghorbani M, Momeni F, Dehghani M Hip circumference, height and risk of type 2 diabetes: systematic review and meta-analysis. Obes Rev 2012, 13:1172-1181.
29. Green J, Cairns BJ, Casabonne D, Wright FL, Reeves G, Beral V Height and cancer incidence in the Million Women Study: prospective cohort, and meta-analysis of prospective studies of height and total cancer risk. Lancet Oncol 2011, 12:785-794. the Million Women Study collaborators.
30. Aune D, Vieira AR, Chan DS, et al. Height and pancreatic cancer risk: a systematic review and meta-analysis of cohort studies. Cancer Causes Control 2012, 23:1213-1222.
31. Liang S, Lv G, Chen W, Jiang J, Wang J Height and kidney cancer risk: a meta-analysis of prospective studies. J Cancer Res Clin Oncol 2014, 141:1799-1807.
32. Zuccolo L, Harris R, Gunnell D, et al. Height and prostate cancer risk: a large nested case-control study (ProtecT) and meta-analysis. Cancer Epidemiol Biomarkers Prev 2008, 17:2325-2336.
33. Nickels S, Truong T, Hein R, et al. Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors. PLoS Genet 2013, 9:e1003284. the Genica Network, the kConFabthe kConFab, the AOCS Management Groupthe AOCS Management Group.
34. Zhang B, Shu XO, Delahanty RJ, et al. Height and breast cancer risk: evidence from prospective studies and Mendelian randomization. J Natl Cancer Inst 2015, 107.
35. Brinton LA, Cook MB, McCormack V, et al. Anthropometric and hormonal risk factors for male breast cancer: male breast cancer pooling project results. J Natl Cancer Inst 2014, 106:djt465. the European Rare Cancer Study Group.
36. Carslake D, Fraser A, Smith GD, et al. Associations of mortality with own height using son's height as an instrumental variable. Econ Hum Biol 2013, 11:351-359.
37. Nelson CP, Hamby SE, Saleheen D, et al. Genetically determined height and coronary artery disease. N Engl J Med 2015, 372:1608-1618. the CARDIoGRAM+C4D Consortium.
38. Nüesch E, Dale C, Palmer TM, et al. Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis. Int J Epidemiol 2015, the EPIC-Netherland Investigators, the UCLEB Investigatorsthe UCLEB Investigators, published online May 15. 10.1093/ije/dyv074.
39. Thrift AP, Gong J, Peters U, et al. Mendelian randomization study of height and risk of colorectal cancer. Int J Epidemiol 2015, 44:662-672. the GIANT Consortium.
40. Davies NM, Gaunt TR, Lewis SJ, et al. The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium. Cancer Causes Control 2015, 26:1603-1616.
41. Gunnell DJ, Davey Smith G, Frankel S, et al. Childhood leg length and adult mortality: follow up of the Carnegie (Boyd Orr) Survey of Diet and Health in Pre-war Britain. J Epidemiol Community Health 1998, 52:142-152.
42. Whitley E, Martin RM, Davey Smith G, Holly JM, Gunnell D The association of childhood height, leg length and other measures of skeletal growth with adult cardiovascular disease: the Boyd-Orr cohort. J Epidemiol Community Health 2012, 66:18-23.
43. Lawlor DA, Ebrahim S, Davey Smith G The association between components of adult height and Type II diabetes and insulin resistance: British Women's Heart and Health Study. Diabetologia 2002, 45:1097-1106.
44. Gunnell D, Okasha M, Smith GD, Oliver SE, Sandhu J, Holly JM Height, leg length, and cancer risk: a systematic review. Epidemiol Rev 2001, 23:313-342.
45. Lawlor DA, Okasha M, Gunnell D, Smith GD, Ebrahim S Associations of adult measures of childhood growth with breast cancer: findings from the British Women's Heart and Health Study. Br J Cancer 2003, 89:81-87.
46. Whitley E, Martin RM, Smith GD, Holly JM, Gunnell D Childhood stature and adult cancer risk: the Boyd Orr cohort. Cancer Causes Control 2009, 20:243-251.
47. Ahlgren M, Melbye M, Wohlfahrt J, Sørensen TI Growth patterns and the risk of breast cancer in women. N Engl J Med 2004, 351:1619-1626.
48. Floud R, Fogel RW, Harris B, Hong SC The changing body: health, nutrition, and human development in the western world since 1700 2011, Cambridge University Press, Cambridge.
49. Song YM, Sung J Adult height and the risk of mortality in South Korean women. Am J Epidemiol 2008, 168:497-505.
50. Wang N, Zhang X, Xiang YB, et al. Associations of adult height and its components with mortality: a report from cohort studies of 135,000 Chinese women and men. Int J Epidemiol 2011, 40:1715-1726.
51. Davey Smith G, Hart C, Upton M, et al. Height and risk of death among men and women: aetiological implications of associations with cardiorespiratory disease and cancer mortality. J Epidemiol Community Health 2000, 54:97-103.
52. Gray L, Davey Smith G, McConnachie A, et al. Parental height in relation to offspring coronary heart disease: examining transgenerational influences on health using the west of Scotland Midspan Family Study. Int J Epidemiol 2012, 41:1776-1785.
53. Stulp G, Buunk AP, Kurzban R, Verhulst S The height of choosiness: mutual mate choice for stature results in suboptimal pair formation for both sexes. Anim Behav 2013, 86:37-46.
54. Sin DD, Wu L, Man SF The relationship between reduced lung function and cardiovascular mortality: a population-based study and a systematic review of the literature. Chest 2005, 127:1952-1959.
55. Arvedsen SK, Damgaard M, Norsk P Body height and blood pressure regulation in humans during anti-orthostatic tilting. Am J Physiol Regul Integr Comp Physiol 2012, 302:R984-R989.
56. Lehrer PM, Gevirtz R Heart rate variability biofeedback: how and why does it work?. Front Psychol 2014, 5:756.
57. Nwasokwa ON, Weiss M, Gladstone C, Bodenheimer MM Higher prevalence and greater severity of coronary disease in short versus tall men referred for coronary arteriography. Am Heart J 1997, 133:147-152.
58. Odegaard JI, Chawla A Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis. Science 2013, 339:172-177.
59. Asao K, Kao WH, Baptiste-Roberts K, Bandeen-Roche K, Erlinger TP, Brancati FL Short stature and the risk of adiposity, insulin resistance, and type 2 diabetes in middle age: the Third National Health and Nutrition Examination Survey (NHANES III), 1988-1994. Diabetes Care 2006, 29:1632-1637.
60. Ben-Shlomo Y, Holly J, McCarthy A, et al. An investigation of fetal, postnatal and childhood growth with insulin-like growth factor I and binding protein 3 in adulthood. Clin Endocrinol (Oxf) 2003, 59:366-373.
61. LeRoith D, Yakar S Mechanisms of disease: metabolic effects of growth hormone and insulin-like growth factor 1. Nat Clin Pract Endocrinol Metab 2007, 3:302-310.
62. Matsuda M, DeFronzo RA Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999, 22:1462-1470.
63. Stefan N, Kantartzis K, Machann J, et al. Identification and characterization of metabolically benign obesity in humans. Arch Intern Med 2008, 168:1609-1616.
64. Shulman GI Ectopic fat in insulin resistance, dyslipidemia, and cardiometabolic disease. N Engl J Med 2014, 371:1131-1141.
65. Stefan N, Häring HU The role of hepatokines in metabolism. Nat Rev Endocrinol 2013, 9:144-152.
66. Pollak M The insulin and insulin-like growth factor receptor family in neoplasia: an update. Nat Rev Cancer 2012, 12:159-169.
67. Crowne EC, Samra JS, Cheetham T, et al. The role of IGF-binding proteins in mediating the effects of recombinant human IGF-I on insulin requirements in type 1 diabetes mellitus. J Clin Endocrinol Metab 2001, 86:3686-3691.
68. Chan JM, Stampfer MJ, Giovannucci E, et al. Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study. Science 1998, 279:563-566.
69. Hankinson SE, Willett WC, Colditz GA, et al. Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet 1998, 351:1393-1396.
70. He M, Xu M, Zhang B, et al. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. Hum Mol Genet 2015, 24:1791-1800.
71. Guevara-Aguirre J, Balasubramanian P, Guevara-Aguirre M, et al. Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans. Sci Transl Med 2011, 3:70ra13.
72. Livingstone C IGF2 and cancer. Endocr Relat Cancer 2013, 20:R321-R339.
73. Liu L, Greenberg S, Russell SM, Nicoll CS Effects of insulin-like growth factors I and II on growth and differentiation of transplanted rat embryos and fetal tissues. Endocrinology 1989, 124:3077-3082.
74. Vigneri P, Frasca F, Sciacca L, Pandini G, Vigneri R Diabetes and cancer. Endocr Relat Cancer 2009, 16:1103-1123.
75. Belardi V, Gallagher EJ, Novosyadlyy R, LeRoith D Insulin and IGFs in obesity-related breast cancer. J Mammary Gland Biol Neoplasia 2013, 18:277-289.
76. Dynkevich Y, Rother KI, Whitford I, et al. Tumors, IGF-2, and hypoglycemia: insights from the clinic, the laboratory, and the historical archive. Endocr Rev 2013, 34:798-826.
77. Lettre G, Jackson AU, Gieger C, et al. Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet 2008, 40:584-591. the Diabetes Genetics Initiative, the FUSIONthe FUSION, the KORAthe KORA, the Prostatethe Prostate, Lung Colorectal and Ovarian Cancer Screening TrialLung Colorectal and Ovarian Cancer Screening Trial, the Nurses' Health Studythe Nurses' Health Study, the SardiNIAthe SardiNIA.
78. Viswanathan SR, Powers JT, Einhorn W, et al. Lin28 promotes transformation and is associated with advanced human malignancies. Nat Genet 2009, 41:843-848.
79. Nishino J, Kim I, Chada K, Morrison SJ Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf expression. Cell 2008, 135:227-239.
80. Trumpp A, Refaeli Y, Oskarsson T, et al. c-Myc regulates mammalian body size by controlling cell number but not cell size. Nature 2001, 414:768-773.
81. Weedon MN, Lettre G, Freathy RM, et al. A common variant of HMGA2 is associated with adult and childhood height in the general population. Nat Genet 2007, 39:1245-1250. Diabetes Genetics Initiative, Wellcome Trust Case Control ConsortiumWellcome Trust Case Control Consortium.
82. Zhu H, Shah S, Shyh-Chang N, et al. Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies. Nat Genet 2010, 42:626-630.
83. Zhu H, Shyh-Chang N, Segrè AV, et al. The Lin28/let-7 axis regulates glucose metabolism. Cell 2011, 147:81-94. the DIAGRAM Consortium, the MAGIC Investigatorsthe MAGIC Investigators.
84. Vander Heiden MG, Cantley LC, Thompson CB Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009, 324:1029-1033.
85. Thornton JE, Gregory RI How does Lin28 let-7 control development and disease?. Trends Cell Biol 2012, 22:474-482.
86. Tomasetti C, Vogelstein B Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions. Science 2015, 347:78-81.
87. Couzin-Frankel J Science Communication. Backlash greets 'bad luck' cancer study and coverage. Science 2015, 347:224.
88. Albanes D, Winick M Are cell number and cell proliferation risk factors for cancer?. J Natl Cancer Inst 1988, 80:772-774.
89. Levine ME, Suarez JA, Brandhorst S, et al. Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population. Cell Metab 2014, 19:407-417.
90. Alexander DD, Cushing CA, Lowe KA, Sceurman B, Roberts MA Meta-analysis of animal fat or animal protein intake and colorectal cancer. Am J Clin Nutr 2009, 89:1402-1409.
91. Giovannucci E, Pollak M, Liu Y, et al. Nutritional predictors of insulin-like growth factor I and their relationships to cancer in men. Cancer Epidemiol Biomarkers Prev 2003, 12:84-89.
92. Holmes MD, Pollak MN, Willett WC, Hankinson SE Dietary correlates of plasma insulin-like growth factor I and insulin-like growth factor binding protein 3 concentrations. Cancer Epidemiol Biomarkers Prev 2002, 11:852-861.
93. Larsson SC, Wolk K, Brismar K, Wolk A Association of diet with serum insulin-like growth factor I in middle-aged and elderly men. Am J Clin Nutr 2005, 81:1163-1167.
94. Cohen P Overview of the IGF-I system. Horm Res 2006, 65(suppl 1):3-8.
95. Cadogan J, Eastell R, Jones N, Barker ME Milk intake and bone mineral acquisition in adolescent girls: randomised, controlled intervention trial. BMJ 1997, 315:1255-1260.
96. Hoppe C, Mølgaard C, Juul A, Michaelsen KF High intakes of skimmed milk, but not meat, increase serum IGF-I and IGFBP-3 in eight-year-old boys. Eur J Clin Nutr 2004, 58:1211-1216.
97. Wiley AS Consumption of milk, but not other dairy products, is associated with height among US preschool children in NHANES 1999-2002. Ann Hum Biol 2009, 36:125-138.
98. Food and Agriculture Organization of the United Nations Statistics Division FAOSTAT, (accessed Feb 12, 2015). http://faostat3.fao.org/home/E.
99. Campbell CD, Ogburn EL, Lunetta KL, et al. Demonstrating stratification in a European American population. Nat Genet 2005, 37:868-872.
100. Markey O, Vasilopoulou D, Givens DI, Lovegrove JA Dairy and cardiovascular health: friend or foe?. Nutr Bull 2014, 39:161-171.
101. Aune D, Norat T, Romundstad P, Vatten LJ Dairy products and the risk of type 2 diabetes: a systematic review and dose-response meta-analysis of cohort studies. Am J Clin Nutr 2013, 98:1066-1083.
102. Aune D, Navarro Rosenblatt DA, Chan DS, et al. Dairy products, calcium, and prostate cancer risk: a systematic review and meta-analysis of cohort studies. Am J Clin Nutr 2015, 101:87-117.
103. Michaëlsson K, Wolk A, Langenskiöld S, et al. Milk intake and risk of mortality and fractures in women and men: cohort studies. BMJ 2014, 349:g6015.
104. Bergholdt HK, Nordestgaard BG, Ellervik C Milk intake is not associated with low risk of diabetes or overweight-obesity: a Mendelian randomization study in 97,811 Danish individuals. Am J Clin Nutr 2015, 102:487-496.
105. Bergholdt HK, Nordestgaard BG, Varbo A, Ellervik C Milk intake is not associated with ischaemic heart disease in observational or Mendelian randomization analyses in 98 529 Danish adults. Int J Epidemiol 2015, 44:587-603.
106. Travis RC, Appleby PN, Siddiq A, et al. Genetic variation in the lactase gene, dairy product intake and risk for prostate cancer in the European prospective investigation into cancer and nutrition. Int J Cancer 2013, 132:1901-1910.
107. Hoppe C, Mølgaard C, Dalum C, Vaag A, Michaelsen KF Differential effects of casein versus whey on fasting plasma levels of insulin, IGF-1 and IGF-1/IGFBP-3: results from a randomized 7-day supplementation study in prepubertal boys. Eur J Clin Nutr 2009, 63:1076-1083.
108. Green DR, Galluzzi L, Kroemer G Cell biology. Metabolic control of cell death. Science 2014, 345:1250256.
109. Brantsaeter AL, Olafsdottir AS, Forsum E, Olsen SF, Thorsdottir I Does milk and dairy consumption during pregnancy influence fetal growth and infant birthweight? A systematic literature review. Food Nutr Res 2012, 56. 10.3402/fnr.v56i0.20050.
110. Barker DJ Maternal nutrition, fetal nutrition, and disease in later life. Nutrition 1997, 13:807-813.
111. Heijmans BT, Tobi EW, Stein AD, et al. Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci USA 2008, 105:17046-17049.
112. Barker DJ, Thornburg KL Placental programming of chronic diseases, cancer and lifespan: a review. Placenta 2013, 34:841-845.
113. Barker DJ, Osmond C, Forsén TJ, Kajantie E, Eriksson JG Trajectories of growth among children who have coronary events as adults. N Engl J Med 2005, 353:1802-1809.
114. Barker DJ, Osmond C, Thornburg KL, Kajantie E, Eriksson JG The shape of the placental surface at birth and colorectal cancer in later life. Am J Hum Biol 2013, 25:566-568.
115. van der Pols JC, Bain C, Gunnell D, Smith GD, Frobisher C, Martin RM Childhood dairy intake and adult cancer risk: 65-y follow-up of the Boyd Orr cohort. Am J Clin Nutr 2007, 86:1722-1729.
116. Wiley AS Cow milk consumption, insulin-like growth factor-I, and human biology: a life history approach. Am J Hum Biol 2012, 24:130-138.
117. Schmidt M, Jacobsen JB, Lash TL, Bøtker HE, Sørensen HT 25 year trends in first time hospitalisation for acute myocardial infarction, subsequent short and long term mortality, and the prognostic impact of sex and comorbidity: a Danish nationwide cohort study. BMJ 2012, 344:e356.
118. Heo M, Kabat GC, Gallagher D, Heymsfield SB, Rohan TE Optimal scaling of weight and waist circumference to height for maximal association with DXA-measured total body fat mass by sex, age and race/ethnicity. Int J Obes (Lond) 2013, 37:1154-1160.
119. Weight-height relationships and body mass index: some observations from the Diverse Populations Collaboration. Am J Phys Anthropol 2005, 128:220-229. Diverse Populations Collaborative Group.