Genetic variation in the lactase gene, dairy product intake and risk for prostate cancer in the European prospective investigation into cancer and nutrition

International Journal of Cancer

Volumn 132, Issue 8, 2013, Pages 1901-1910

  Travis, Ruth C ^a   Appleby, Paul N ^a   Siddiq, Afshan ^b   Allen, Naomi E ^a   Kaaks, Rudolf ^c   Canzian, Federico ^c   Feller, Silke ^d   Tjønneland, Anne ^e   Føns Johnsen, Nina ^e   Overvad, Kim ^f   Ramon Quiros J ^g   González, Carlos A ^h   Sánchez, Maria José ⁱ   Larrañaga, Nerea ^j   Chirlaque, Maria Dolores ^k   Barricarte, Aurelio ^l   Khaw, Kay Tee ^m   Wareham, Nick ⁿ   Trichopoulou, Antonia ^o,p   Valanou, Elisavet ^p   Oustoglou, Erifili ^p   Palli, Domenico ^q   Sieri, Sabina ^r   Tumino, Rosario ^s   Sacerdote, Carlotta ^t   Bueno De Mesquita, H B ^u,v   Stattin, Pär ^w   Ferrari, Pietro ^x   Johansson, Mattias ^w,x   Norat, Teresa ^b   Riboli, Elio ^b   Key, Timothy J ^a   more..

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^e INSTITUTE OF CANCER EPIDEMIOLOGY   (Denmark)

^f AARHUS UNIVERSITY HOSPITAL   (Denmark)

^g PUBLIC HEALTH DIRECTORATE   (Spain)

^h CATALAN INSTITUTE OF ONCOLOGY   (Spain)

ⁱ ANDALUSIAN SCHOOL OF PUBLIC HEALTH   (Spain)

^j CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^k DEPARTMENT OF EPIDEMIOLOGY   (Spain)

^l INSTITUTO DE SALUD PÚBLICA DE NAVARRA   (Spain)

^m UNIVERSITY OF CAMBRIDGE   (United Kingdom)

ⁿ MRC EPIDEMIOLOGY UNIT   (United Kingdom)

^o UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^p HELLENIC HEALTH FOUNDATION   (Greece)

^q CANCER RESEARCH AND PREVENTION INSTITUTE ISPO   (Italy)

^r NATIONAL CANCER INSTITUTE   (Italy)

^s CIVILE M P AREZZO HOSPITAL   (Italy)

^t Human Genetics Foundation   (Italy)

^u NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^v UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^w UMEÅ UNIVERSITY   (Sweden)

^x INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

more..

Author keywords

dairy; genetic; lactase; polymorphism; prostate cancer

Indexed keywords

LACTASE;

ADULT; AGED; ALLELE; CANCER RISK; CASE CONTROL STUDY; CONTROLLED STUDY; DAIRY PRODUCT; DENMARK; FOOD INTAKE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; GREECE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; ITALY; LCT GENE; MALE; MILK; NETHERLANDS; PRIORITY JOURNAL; PROSTATE CANCER; QUESTIONNAIRE; REVIEW; SPAIN; UNITED KINGDOM;

CASE-CONTROL STUDIES; DAIRY PRODUCTS; EUROPE; GENETIC VARIATION; HUMANS; LACTASE; MALE; PROSTATIC NEOPLASMS; RISK FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 84873992032     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.27836     Document Type: Review

References (39)

1. Allen NE, Key TJ, Appleby PN, et al. Animal foods, protein, calcium and prostate cancer risk: the European Prospective Investigation into Cancer and Nutrition. Br J Cancer 2008; 98: 1574-81.
2. Ahn J, Albanes D, Peters U, et al. Dairy products, calcium intake, and risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Epidemiol Biomarkers Prev 2007; 16: 2623-30.
3. Gao X, LaValley MP, Tucker KL,. Prospective studies of dairy product and calcium intakes and prostate cancer risk: a meta-analysis. J Natl Cancer Inst 2005; 97: 1768-77.
4. Mitrou PN, Albanes D, Weinstein SJ, et al. A prospective study of dietary calcium, dairy products and prostate cancer risk (Finland). Int J Cancer 2007; 120: 2466-73.
5. Park SY, Murphy SP, Wilkens LR, et al. Calcium, vitamin D, and dairy product intake and prostate cancer risk: the Multiethnic Cohort Study. Am J Epidemiol 2007; 166: 1259-69.
6. Park Y, Mitrou PN, Kipnis V, et al. Calcium, dairy foods, and risk of incident and fatal prostate cancer: the NIH-AARP Diet and Health Study. Am J Epidemiol 2007; 166: 1270-9.
7. Rohrmann S, Platz EA, Kavanaugh CJ, et al. Meat and dairy consumption and subsequent risk of prostate cancer in a US cohort study. Cancer Causes Control 2007; 18: 41-50.
8. Qin LQ, Xu JY, Wang PY, et al. Milk consumption is a risk factor for prostate cancer in Western countries: evidence from cohort studies. Asia Pac J Clin Nutr 2007; 16: 467-76.
9. Severi G, English DR, Hopper JL, et al. Re: prospective studies of dairy product and calcium intakes and prostate cancer risk: a meta-analysis. J Natl Cancer Inst 2006; 98: 794-5; author reply 5.
10. Enattah NS, Sahi T, Savilahti E, et al. Identification of a variant associated with adult-type hypolactasia. Nat Genet 2002; 30: 233-7.
11. Weiss KM,. The unkindest cup. Lancet 2004; 363: 1489-90.
12. Beja-Pereira A, Luikart G, England PR, et al. Gene-culture coevolution between cattle milk protein genes and human lactase genes. Nat Genet 2003; 35: 311-13.
13. Sacerdote C, Guarrera S, Smith GD, et al. Lactase persistence and bitter taste response: instrumental variables and mendelian randomization in epidemiologic studies of dietary factors and cancer risk. Am J Epidemiol 2007; 166: 576-81.
14. Smith GD, Lawlor DA, Timpson NJ, et al. Lactase persistence-related genetic variant: population substructure and health outcomes. Eur J Hum Genet 2009; 17: 357-67.
15. Torniainen S, Hedelin M, Autio V, et al. Lactase persistence, dietary intake of milk, and the risk for prostate cancer in Sweden and Finland. Cancer Epidemiol Biomarkers Prev 2007; 16: 956-61.
16. Davey Smith G, Ebrahim S,. 'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? Int J Epidemiol 2003; 32: 1-22.
17. Davey Smith G, Ebrahim S,. What can mendelian randomisation tell us about modifiable behavioural and environmental exposures? BMJ 2005; 330: 1076-9.
18. Timpson NJ, Brennan P, Gaborieau V, et al. Can lactase persistence genotype be used to reassess the relationship between renal cell carcinoma and milk drinking? Potentials and problems in the application of Mendelian randomization. Cancer Epidemiol Biomarkers Prev 2010; 19: 1341-8.
19. Riboli E, Hunt KJ, Slimani N, et al. European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection. Public Health Nutr 2002; 5: 1113-24.
20. Deharveng G, Charrondiere UR, Slimani N, et al. Comparison of nutrients in the food composition tables available in the nine European countries participating in EPIC. European Prospective Investigation into Cancer and Nutrition. Eur J Clin Nutr 1999; 53: 60-79.
21. Slimani N, Deharveng G, Unwin I, et al. The EPIC nutrient database project (ENDB): a first attempt to standardize nutrient databases across the 10 European countries participating in the EPIC study. Eur J Clin Nutr 2007; 61: 1037-56.
22. Travis RC, Spencer EA, Allen NE, et al. Plasma phyto-oestrogens and prostate cancer in the European Prospective Investigation into Cancer and Nutrition. Br J Cancer 2009; 100: 1817-23.
23. Linseisen J, Rohrmann S, Miller AB, et al. Fruit and vegetable consumption and lung cancer risk: updated information from the European Prospective Investigation into Cancer and Nutrition (EPIC). Int J Cancer 2007; 121: 1103-14.
24. Price AJ, Allen NE, Appleby PN, et al. Plasma phytanic acid concentration and risk of prostate cancer: results from the European Prospective Investigation into Cancer and Nutrition. Am J Clin Nutr 2010; 91: 1769-76.
25. Travis RC, Crowe FL, Allen NE, et al. Serum vitamin D and risk of prostate cancer in a case-control analysis nested within the European Prospective Investigation into Cancer and Nutrition (EPIC). Am J Epidemiol 2009; 169: 1223-32.
26. Travis RC, Key TJ, Allen NE, et al. Serum androgens and prostate cancer among 643 cases and 643 controls in the European Prospective Investigation into Cancer and Nutrition. Int J Cancer 2007; 121: 1331-8.
27. StataCorp. Stata Statistical Software: Release 10 College Station, TX: StataCorp LP, 2007.
28. Bersaglieri T, Sabeti PC, Patterson N, et al. Genetic signatures of strong recent positive selection at the lactase gene. Am J Hum Genet 2004; 74: 1111-20.
29. Kuokkanen M, Enattah NS, Oksanen A, et al. Transcriptional regulation of the lactase-phlorizin hydrolase gene by polymorphisms associated with adult-type hypolactasia. Gut 2003; 52: 647-52.
30. Koek WN, van Meurs JB, van der Eerden BC, et al. The T-13910C polymorphism in the lactase phlorizin hydrolase gene is associated with differences in serum calcium levels and calcium intake. J Bone Mineral Res: The Official J Am Soc Bone Mineral Res 2010; 25: 1980-7.
31. Campbell AK, Matthews SB, Vassel N, et al. Bacterial metabolic 'toxins': a new mechanism for lactose and food intolerance, and irritable bowel syndrome. Toxicology 2010; 278: 268-76.
32. Crowe FL, Key TJ, Allen NE, et al. The association between diet and serum concentrations of IGF-I, IGFBP-1, IGFBP-2, and IGFBP-3 in the European Prospective Investigation into Cancer and Nutrition. Cancer Epidemiol Biomarkers Prev 2009; 18: 1333-40.
33. Huncharek M, Muscat J, Kupelnick B,. Dairy products, dietary calcium and vitamin D intake as risk factors for prostate cancer: a meta-analysis of 26,769 cases from 45 observational studies. Nutr Cancer 2008; 60: 421-41.
34. Kesse E, Bertrais S, Astorg P, et al. Dairy products, calcium and phosphorus intake, and the risk of prostate cancer: results of the French prospective SU.VI.MAX (Supplementation en Vitamines et Mineraux Antioxydants) study. Br J Nutr 2006; 95: 539-45.
35. Koh KA, Sesso HD, Paffenbarger RS, et al. Dairy products, calcium and prostate cancer risk. Br J Cancer 2006; 95: 1582-5.
36. Kurahashi N, Inoue M, Iwasaki M, et al. Dairy product, saturated fatty acid, and calcium intake and prostate cancer in a prospective cohort of Japanese men. Cancer Epidemiol Biomarkers Prev 2008; 17: 930-7.
37. Tseng M, Breslow RA, Graubard BI, et al. Dairy, calcium, and vitamin D intakes and prostate cancer risk in the National Health and Nutrition Examination Epidemiologic Follow-up Study cohort. Am J Clin Nutr 2005; 81: 1147-54.
38. Tseng M, Giri V, Watkins-Bruner D, et al. Dairy intake and 1,25-dihydroxyvitamin D levels in men at high risk for prostate cancer. Cancer Causes Control 2009; 20: 1947-54.
39. von Hinke Kessler Scholder S, Smith GD, Lawlor DA, et al. Mendelian randomization: the use of genes in instrumental variable analyses. Health Econ 2011; 20: 893-6.