메뉴 건너뛰기




Volumn 153, Issue 7, 2012, Pages 3029-3039

Antiaging gene Klotho enhances glucose-induced insulin secretion by up-regulating plasma membrane levels of TRPV2 in MIN6 β-cells

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; GLUCOSE; INSULIN; KLOTHO PROTEIN; SMALL INTERFERING RNA; TRANILAST; VANILLOID RECEPTOR 2;

EID: 84862739884     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2012-1091     Document Type: Article
Times cited : (61)

References (41)
  • 1
    • 64649104158 scopus 로고    scopus 로고
    • Banting Lecture. From the triumvirate to the ominous octet: A new paradigm for the treatment of type 2 diabetes mellitus
    • Defronzo RA 2009 Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. Diabetes 58:773-795
    • (2009) Diabetes , vol.58 , pp. 773-795
    • Defronzo, R.A.1
  • 2
    • 78651441827 scopus 로고    scopus 로고
    • Thyroid hormone potentiates insulin signaling and attenuates hyperglycemia and insulin resistance in a mouse model of type 2 diabetes
    • Lin Y, Sun Z 2011 Thyroid hormone potentiates insulin signaling and attenuates hyperglycemia and insulin resistance in a mouse model of type 2 diabetes. Br J Pharmacol 162:597-610
    • (2011) Br J Pharmacol , vol.162 , pp. 597-610
    • Lin, Y.1    Sun, Z.2
  • 3
    • 38149042694 scopus 로고    scopus 로고
    • An overview of pancreatic β-cell defects in human type 2 diabetes: Implications for treatment
    • Marchetti P, Dotta F, Lauro D, Purrello F 2008 An overview of pancreatic β-cell defects in human type 2 diabetes: implications for treatment. Regul Pept 146:4-11
    • (2008) Regul Pept , vol.146 , pp. 4-11
    • Marchetti, P.1    Dotta, F.2    Lauro, D.3    Purrello, F.4
  • 4
    • 30844471395 scopus 로고    scopus 로고
    • Diabetes mellitus in the elderly: Insulin resistance and/or impaired insulin secretion?
    • Scheen AJ 2005 Diabetes mellitus in the elderly: insulin resistance and/or impaired insulin secretion? Diabetes Metab 31(Spec No. 2): 5S27-5S34
    • (2005) Diabetes Metab , vol.31 , Issue.SPEC NO. 2
    • Scheen, A.J.1
  • 5
    • 64149126546 scopus 로고    scopus 로고
    • Regulation of insulin secretion: A matter of phase control and amplitude modulation
    • Henquin JC 2009 Regulation of insulin secretion: a matter of phase control and amplitude modulation. Diabetologia 52:739-751
    • (2009) Diabetologia , vol.52 , pp. 739-751
    • Henquin, J.C.1
  • 6
    • 66849115296 scopus 로고    scopus 로고
    • Mechanisms of biphasic insulin-granule exocytosis-roles of the cytoskeleton, small GTPases and SNARE proteins
    • WangZ, ThurmondDC2009 Mechanisms of biphasic insulin-granule exocytosis-roles of the cytoskeleton, small GTPases and SNARE proteins. J Cell Sci 122:893-903
    • (2009) J Cell Sci , vol.122 , pp. 893-903
    • Wang, Z.1    Thurmond, D.C.2
  • 7
    • 78649536834 scopus 로고    scopus 로고
    • Insulin/phosphoinositide 3-kinase pathway accelerates the glucose-induced first-phase insulin secretion through TrpV2 recruitment in pancreatic β-cells
    • Aoyagi K, Ohara-Imaizumi M, Nishiwaki C, Nakamichi Y, Nagamatsu S 2010 Insulin/phosphoinositide 3-kinase pathway accelerates the glucose-induced first-phase insulin secretion through TrpV2 recruitment in pancreatic β-cells. Biochem J 432:375-386.
    • (2010) Biochem J , vol.432 , pp. 375-386
    • Aoyagi, K.1    Ohara-Imaizumi, M.2    Nishiwaki, C.3    Nakamichi, Y.4    Nagamatsu, S.5
  • 8
    • 63249120875 scopus 로고    scopus 로고
    • Regulation of calcium-permeable TRPV2 channel by insulin in pancreatic β-cells
    • Hisanaga E, Nagasawa M, Ueki K, Kulkarni RN, Mori M, Kojima I 2009 Regulation of calcium-permeable TRPV2 channel by insulin in pancreatic β-cells. Diabetes 58:174-184
    • (2009) Diabetes , vol.58 , pp. 174-184
    • Hisanaga, E.1    Nagasawa, M.2    Ueki, K.3    Kulkarni, R.N.4    Mori, M.5    Kojima, I.6
  • 9
    • 0033119629 scopus 로고    scopus 로고
    • A capsaicin-receptor homologue with a high threshold for noxious heat
    • DOI 10.1038/18906
    • Caterina MJ, Rosen TA, Tominaga M, Brake AJ, Julius D 1999 A capsaicin-receptor homologue with a high threshold for noxious heat. Nature 398:436-441 (Pubitemid 29180377)
    • (1999) Nature , vol.398 , Issue.6726 , pp. 436-441
    • Caterina, M.J.1    Rosen, T.A.2    Tominaga, M.3    Brake, A.J.4    Julius, D.5
  • 10
    • 0033162068 scopus 로고    scopus 로고
    • Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I
    • Kanzaki M, Zhang YQ, Mashima H, Li L, Shibata H, Kojima I 1999 Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I. Nat Cell Biol 1:165-170 (Pubitemid 129656021)
    • (1999) Nature Cell Biology , vol.1 , Issue.3 , pp. 165-170
    • Kanzaki, M.1    Zhang, Y.-Q.2    Mashima, H.3    Li, L.4    Shibata, H.5    Kojima, I.6
  • 13
    • 0242266967 scopus 로고    scopus 로고
    • TRPV2 Is a Component of Osmotically Sensitive Cation Channels in Murine Aortic Myocytes
    • DOI 10.1161/01.RES.0000097263.10220.0C
    • Muraki K, Iwata Y, Katanosaka Y, Ito T, Ohya S, Shigekawa M, Imaizumi Y 2003 TRPV2 is a component of osmotically sensitive cation channels in murine aortic myocytes. Circ Res 93:829-838 (Pubitemid 37363057)
    • (2003) Circulation Research , vol.93 , Issue.9 , pp. 829-838
    • Muraki, K.1    Iwata, Y.2    Katanosaka, Y.3    Ito, T.4    Ohya, S.5    Shigekawa, M.6    Imaizumi, Y.7
  • 14
    • 46749129338 scopus 로고    scopus 로고
    • TRPV2is activated by cannabidiol and mediatesCGRPrelease in cultured rat dorsal root ganglion neurons
    • Qin N, Neeper MP, Liu Y, Hutchinson TL, Lubin ML, Flores CM 2008TRPV2is activated by cannabidiol and mediatesCGRPrelease in cultured rat dorsal root ganglion neurons. J Neurosci 28:6231-6238
    • (2008) J Neurosci , vol.28 , pp. 6231-6238
    • Qin, N.1    Neeper, M.P.2    Liu, Y.3    Hutchinson, T.L.4    Lubin, M.L.5    Flores, C.M.6
  • 16
    • 27144440831 scopus 로고    scopus 로고
    • Cell signalling: The β-glucuronidase klotho hydrolyzes and activates the TRPV5 channel
    • DOI 10.1126/science.1114245
    • Chang Q, Hoefs S, van der Kemp AW, Topala CN, Bindels RJ, Hoenderop JG 2005 The β-glucuronidase klotho hydrolyzes and activates the TRPV5 channel. Science (New York, NY) 310:490-493 (Pubitemid 41507962)
    • (2005) Science , vol.310 , Issue.5747 , pp. 490-493
    • Chang, Q.1    Hoefs, S.2    Van Der, K.A.W.3    Topala, C.N.4    Bindels, R.J.5    Hoenderop, J.G.6
  • 17
    • 57749190558 scopus 로고    scopus 로고
    • Current understanding of klotho
    • Wang Y, Sun Z 2009 Current understanding of klotho. Ageing Res Rev 8:43-51
    • (2009) Ageing Res Rev , vol.8 , pp. 43-51
    • Wang, Y.1    Sun, Z.2
  • 20
    • 0032489424 scopus 로고    scopus 로고
    • Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein
    • DOI 10.1016/S0014-5793(98)00127-6, PII S0014579398001276
    • Shiraki-Iida T, Aizawa H, Matsumura Y, Sekine S, Iida A, Anazawa H, Nagai R, Kuro-o M, Nabeshima Y 1998 Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein. FEBS Lett 424:6-10 (Pubitemid 28130341)
    • (1998) FEBS Letters , vol.424 , Issue.1-2 , pp. 6-10
    • Shiraki-Iida, T.1    Aizawa, H.2    Matsumura, Y.3    Sekine, S.4    Iida, A.5    Anazawa, H.6    Nagai, R.7    Kuro-O, M.8    Nabeshima, Y.-I.9
  • 22
    • 2342610541 scopus 로고    scopus 로고
    • Secreted Klotho protein in sera and CSF: Implication for post-translational cleavage in release of Klotho protein from cell membrane
    • DOI 10.1016/j.febslet.2004.03.090, PII S0014579304003990
    • Imura A, Iwano A, Tohyama O, Tsuji Y, Nozaki K, Hashimoto N, Fujimori T, Nabeshima Y 2004 Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane. FEBS Lett 565:143-147 (Pubitemid 38595335)
    • (2004) FEBS Letters , vol.565 , Issue.1-3 , pp. 143-147
    • Imura, A.1    Iwano, A.2    Tohyama, O.3    Tsuji, Y.4    Nozaki, K.5    Hashimoto, N.6    Fujimori, T.7    Nabeshima, Y.-I.8
  • 25
    • 0025281303 scopus 로고
    • Establishment of a pancreatic β cell line that retains glucose-inducible insulin secretion: Special reference to expression of glucose transporter isoforms
    • Miyazaki J, Araki K, Yamato E, Ikegami H, Asano T, Shibasaki Y, Oka Y, Yamamura K 1990 Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms. Endocrinology 127: 126-132 (Pubitemid 20228111)
    • (1990) Endocrinology , vol.127 , Issue.1 , pp. 126-132
    • Miyazaki, J.-I.1    Araki, K.2    Yamato, E.3    Ikegami, H.4    Asano, T.5    Shibasaki, Y.6    Oka, Y.7    Yamamura, K.-I.8
  • 26
    • 70349659193 scopus 로고    scopus 로고
    • Klotho gene delivery prevents the progression of spontaneous hypertension and renal damage
    • Wang Y, Sun Z 2009 Klotho gene delivery prevents the progression of spontaneous hypertension and renal damage. Hypertension 54: 810-817
    • (2009) Hypertension , vol.54 , pp. 810-817
    • Wang, Y.1    Sun, Z.2
  • 28
    • 1542380960 scopus 로고    scopus 로고
    • Hippocampal CA1 region neurodegeneration produced by ethanol withdrawal requires activation of intrinsic polysynaptic hippocampal pathways and function of N-methyl-D-aspartate receptors
    • DOI 10.1016/j.neuroscience.2003.12.013, PII S0306452203009345
    • Prendergast MA, Harris BR, Mullholland PJ, Blanchard 2nd JA, Gibson DA, Holley RC, Littleton JM 2004 Hippocampal CA1 region neurodegeneration produced by ethanol withdrawal requires activation of intrinsic polysynaptic hippocampal pathways and function of N-methyl-D-aspartate receptors. Neuroscience 124: 869-877 (Pubitemid 38328776)
    • (2004) Neuroscience , vol.124 , Issue.4 , pp. 869-877
    • Prendergast, M.A.1    Harris, B.R.2    Mullholland, P.J.3    Blanchard II, J.A.4    Gibson, D.A.5    Holley, R.C.6    Littleton, J.M.7
  • 29
    • 34347249558 scopus 로고    scopus 로고
    • Adrenomedullin stimulates nitric oxide production from primary rat hypothalamic neurons: Roles of calcium and phosphatases
    • DOI 10.1124/mol.106.033761
    • Xu Y, Krukoff TL 2007 Adrenomedullin stimulates nitric oxide production from primary rat hypothalamic neurons: roles of calcium and phosphatases. Mol Pharmacol 72:112-120 (Pubitemid 46998530)
    • (2007) Molecular Pharmacology , vol.72 , Issue.1 , pp. 112-120
    • Xu, Y.1    Krukoff, T.L.2
  • 31
    • 0037261338 scopus 로고    scopus 로고
    • Fractionation analysis of the subcellular distribution of GLUT-4 in 3T3-L1 adipocytes
    • Elmendorf JS 2003 Fractionation analysis of the subcellular distribution of GLUT-4 in 3T3-L1 adipocytes. Methods Mol Med 83: 105-111
    • (2003) Methods Mol Med , vol.83 , pp. 105-111
    • Elmendorf, J.S.1
  • 32
    • 80054113073 scopus 로고    scopus 로고
    • Genetic interleukin-10 deficiency causes vascular remodeling via the upregulation of Nox1
    • Dammanahalli JK, Wang X, Sun Z 2011 Genetic interleukin-10 deficiency causes vascular remodeling via the upregulation of Nox1. J Hypertens 29:2116-2125
    • (2011) J Hypertens , vol.29 , pp. 2116-2125
    • Dammanahalli, J.K.1    Wang, X.2    Sun, Z.3
  • 33
    • 85011453144 scopus 로고    scopus 로고
    • Activation of calcium-permeable cation channel by insulin in Chinese hamster ovary cells expressing human insulin receptors
    • DOI 10.1210/en.139.1.179
    • Nie L, Kanzaki M, Shibata H, Kojima I 1998 Activation of calcium-permeable cation channel by insulin in Chinese hamster ovary cells expressing human insulin receptors. Endocrinology 139:179-188 (Pubitemid 28166307)
    • (1998) Endocrinology , vol.139 , Issue.1 , pp. 179-188
    • Nie, L.1    Kanzaki, M.2    Shibata, H.3    Kojima, I.4
  • 34
    • 0030880444 scopus 로고    scopus 로고
    • 2+-permeable channel
    • DOI 10.1016/S0143-4160(97)90107-X
    • Nie L, Oishi Y, Doi I, Shibata H, Kojima I 1997 Inhibition of proliferation of MCF-7 breast cancer cells by a blocker of Ca(2+)-permeable channel. Cell Calcium 22:75-82 (Pubitemid 27390421)
    • (1997) Cell Calcium , vol.22 , Issue.2 , pp. 75-82
    • Nie, L.1    Oishi, Y.2    Doi, I.3    Shibata, H.4    Kojima, I.5
  • 35
    • 0033857373 scopus 로고    scopus 로고
    • Glucose uptake, utilization, and signaling in GLUT2-null islets
    • Guillam MT, Dupraz P, Thorens B 2000 Glucose uptake, utilization, and signaling in GLUT2-null islets. Diabetes 49:1485-1491
    • (2000) Diabetes , vol.49 , pp. 1485-1491
    • Guillam, M.T.1    Dupraz, P.2    Thorens, B.3
  • 36
    • 66849104240 scopus 로고    scopus 로고
    • Pharmacology of vanilloid transient receptor potential cation channels
    • Vriens J, Appendino G, Nilius B 2009 Pharmacology of vanilloid transient receptor potential cation channels. Mol Pharmacol 75: 1262-1279
    • (2009) Mol Pharmacol , vol.75 , pp. 1262-1279
    • Vriens, J.1    Appendino, G.2    Nilius, B.3
  • 38
    • 33745863033 scopus 로고    scopus 로고
    • Islet β cell failure in type 2 diabetes
    • DOI 10.1172/JCI29103
    • PrentkiM,Nolan CJ 2006 Islet β cell failure in type 2 diabetes. J Clin Invest 116:1802-1812 (Pubitemid 44033300)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.7 , pp. 1802-1812
    • Prentki, M.1    Nolan, C.J.2
  • 41
    • 80052101334 scopus 로고    scopus 로고
    • Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation
    • Zhao Y, Banerjee S, Dey N, LeJeune WS, Sarkar PS, Brobey R, Rosenblatt KP, Tilton RG, Choudhary S 2011 Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation. Diabetes 60:1907-1916
    • (2011) Diabetes , vol.60 , pp. 1907-1916
    • Zhao, Y.1    Banerjee, S.2    Dey, N.3    LeJeune, W.S.4    Sarkar, P.S.5    Brobey, R.6    Rosenblatt, K.P.7    Tilton, R.G.8    Choudhary, S.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.