Metformin induces apoptosis via a mitochondria-mediated pathway in human breast cancer cells in vitro

Experimental and Therapeutic Medicine

Volumn 11, Issue 5, 2016, Pages 1700-1706

  Gao, Zhen Yuan ^a   Liu, Zhe ^b   Bi, Ming Hong ^b   Zhang, Jing Jing ^b   Han, Zheng Quan ^b   Han, Xiao ^b   Wang, Hong Ya ^b   Sun, Guo Ping ^a   Liu, Hao ^b  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b BENGBU MEDICAL COLLEGE   (China)

Author keywords

Apoptosis; Breast cancer; Mediated pathway; Metformin; Mitochondria

Indexed keywords

ADENOSINE TRIPHOSPHATE; METFORMIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MCL 1; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; ASSAY; BREAST CANCER CELL LINE; CANCER GROWTH; CASPASE INHIBITION ASSAY; CELL PROLIFERATION; CELL VIABILITY; CFU COUNTING; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; MDA MB 231 CELL LINE; MDA MB 435 CELL LINE; MITOCHONDRIA MEDIATED APOPTOSIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MTT ASSAY; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING;

EID: 84961844568     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2016.3143     Document Type: Article

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