P2X7 Receptor Suppression Preserves Blood-Brain Barrier through Inhibiting RhoA Activation after Experimental Intracerebral Hemorrhage in Rats

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Zhao, Hengli ^a   Zhang, Xuan ^a   Dai, Zhiqiang ^a   Feng, Yang ^a   Li, Qiang ^a   Zhang, John H ^b   Liu, Xin ^a   Chen, Yujie ^a   Feng, Hua ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3'-O-(4-BENZOYL)BENZOYLADENOSINE 5'-TRIPHOSPHATE; 3-(5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL)METHYLPYRIDINE; ADENOSINE TRIPHOSPHATE; CADHERIN; LEUKOCYTE ANTIGEN; OCCLUDIN; OCLN PROTEIN, RAT; PROTEIN ZO1; PURINERGIC P2X RECEPTOR ANTAGONIST; PURINERGIC P2X7 RECEPTOR; PYRIDINE DERIVATIVE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; TETRAZOLE DERIVATIVE; TJP1 PROTEIN, RAT; VASCULAR ENDOTHELIAL CADHERIN;

ANALOGS AND DERIVATIVES; ANIMAL; BLOOD BRAIN BARRIER; BRAIN; CEREBRAL HEMORRHAGE; DRUG EFFECTS; ENZYME ACTIVATION; GENE EXPRESSION; GENE SILENCING; GENETICS; MALE; METABOLISM; PATHOLOGY; RNA INTERFERENCE; SPRAGUE DAWLEY RAT; VASCULARIZATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIGENS, CD; BLOOD-BRAIN BARRIER; BRAIN; CADHERINS; CEREBRAL HEMORRHAGE; ENZYME ACTIVATION; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; MALE; OCCLUDIN; PURINERGIC P2X RECEPTOR ANTAGONISTS; PYRIDINES; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P2X7; RHOA GTP-BINDING PROTEIN; RNA INTERFERENCE; RNA, SMALL INTERFERING; TETRAZOLES; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84961840150     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep23286     Document Type: Article

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