P2X7 receptor antagonism inhibits p38 mitogen-activated protein kinase activation and ameliorates neuronal apoptosis after subarachnoid hemorrhage in rats

Critical Care Medicine

Volumn 41, Issue 12, 2013, Pages

  Chen, Sheng ^a,b   Ma, Qingyi ^b   Krafft, Paul R ^b   Chen, Yujie ^b   Tang, Jiping ^b   Zhang, Jianmin ^a   Zhang, John H ^b  

^a Second Affiliated Hospital   (China)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Brilliant blue G; Early brain injury; P2X7 receptor; P38 mitogen activated protein kinase; Subarachnoid hemorrhage

Indexed keywords

2'(3') O (4 BENZOYLBENZOYL)ADENOSINE 5' TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE; BRILLIANT BLUE; BRILLIANT BLUE G; CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL 2; PURINERGIC P2X7 RECEPTOR; PURINERGIC P2X7 RECEPTOR ANTAGONIST; RECEPTOR BLOCKING AGENT; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN EDEMA; BRAIN INJURY; BRAIN WATER; CONTROLLED STUDY; IMMUNOFLUORESCENCE; IN VIVO STUDY; LEFT HEMISPHERE; MALE; NEURONAL APOPTOSIS; NICK END LABELING; NONHUMAN; OUTCOME ASSESSMENT; PERFORATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCORING SYSTEM; SUBARACHNOID HEMORRHAGE; SUBCORTEX; WATER CONTENT; WESTERN BLOTTING;

EID: 84889238770     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31829a8246     Document Type: Article

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