TGF-β/Smad3 signalling regulates the transition of bone marrowderived macrophages into myofibroblasts during tissue fibrosis

Oncotarget

Volumn 7, Issue 8, 2016, Pages 8809-8822

  Wang, Shuang ^a   Meng, Xiao Ming ^a   Ng, Yee Yung ^b   Ma, Frank Y ^c   Zhou, Shuang ^a   Zhang, Yang ^a   Yang, Chen ^a   Huang, Xiao Ru ^a   Xiao, Jun ^a   Wang, Ying Ying ^a   Ka, Shuk Man ^a   Tang, Yong Jiang ^a   Chung, Arthur C K ^a   To, Ka Fai ^a   Nikolic Paterson, David J ^c   Lan, Hui Yao ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c MONASH UNIVERSITY   (Australia)

Author keywords

Lineage tracing; Macrophage myofibroblast transition (MMT); Renal fibrosis; Smad3; TGF beta

Indexed keywords

COLLAGEN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; GREEN FLUORESCENT PROTEIN; MESSENGER RNA;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CELL LINEAGE; CELL TRANSFORMATION; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE DELETION; IN VITRO STUDY; KIDNEY FIBROSIS; MACROPHAGE; MACROPHAGE MYOFIBROBLAST TRANSITION; MONOCYTE; MOUSE; MYOFIBROBLAST; NONHUMAN; PATHOGENESIS; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; URETER OBSTRUCTION; ANIMAL; C57BL MOUSE; CELL CULTURE; CONFOCAL MICROSCOPY; ENZYME IMMUNOASSAY; FEMALE; FIBROSIS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; KIDNEY DISEASE; KNOCKOUT MOUSE; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BONE MARROW; CELLS, CULTURED; FEMALE; FIBROSIS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GREEN FLUORESCENT PROTEINS; IMMUNOENZYME TECHNIQUES; KIDNEY DISEASES; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MYOFIBROBLASTS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84961669760     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6604     Document Type: Article

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