Adiponectin promotes monocyte-to-fibroblast transition in renal fibrosis

Journal of the American Society of Nephrology

Volumn 24, Issue 10, 2013, Pages 1644-1659

  Yang, Jun ^a   Lin, Song Chang ^a   Chen, Gang ^a,b   He, Liqun ^b   Hu, Zhaoyong ^a   Chan, Lawrence ^c   Trial, Jo Ann ^d   Entman, Mark L ^d   Wang, Yanlin ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c Shuguang Hospital   (China)

^d DeBakey Heart Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; ALPHA SMOOTH MUSCLE ACTIN; CHEMOKINE; COLLAGEN TYPE 1; FIBRONECTIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROCOLLAGEN; SCLEROPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL ACTIVATION; CELL COUNT; CELL DIFFERENTIATION; CELL ISOLATION; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DISEASE COURSE; FIBROBLAST; KIDNEY CELL; KIDNEY FIBROSIS; KNOCKOUT MOUSE; MACROPHAGE; MALE; MONOCYTE; MOUSE; MYOFIBROBLAST; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; WILD TYPE;

EID: 84885076864     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2013030217     Document Type: Article

References (48)

1. Schainuck LI, Striker GE, Cutler RE, Benditt EP: Structural-functional correlations in renal disease. II. The correlations. Hum Pathol 1: 631-641, 1970
2. Nath KA: The tubulointerstitium in progressive renal disease. Kidney Int 54: 992-994, 1998
3. Neilson EG: Mechanisms of disease: Fibroblasts-a new look at an old problem. Nat Clin Pract Nephrol 2: 101-108, 2006
4. Strutz F, Müller GA: Renal fibrosis and the origin of the renal fibroblast. Nephrol Dial Transplant 21: 3368-3370, 2006
5. Liu Y: Renal fibrosis: New insights into the pathogenesis and therapeutics. Kidney Int 69: 213-217, 2006
6. Iwano M, Plieth D, Danoff TM, Xue C, Okada H, Neilson EG: Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest 110: 341-350, 2002
7. Sakai N, Wada T, Yokoyama H, Lipp M, Ueha S, Matsushima K, Kaneko S: Secondary lymphoid tissue chemokine (SLC/CCL21) /CCR7 signaling regulates fibrocytes in renal fibrosis. Proc Natl Acad Sci U S A 103: 14098-14103, 2006
8. Grimm PC, Nickerson P, Jeffery J, Savani RC, Gough J, McKenna RM, Stern E, Rush DN: Neointimal and tubulointerstitial infiltration by recipient mesenchymal cells in chronic renal-allograft rejection. N Engl J Med 345: 93-97, 2001
9. Broekema M, Harmsen MC, van Luyn MJ, Koerts JA, Petersen AH, van Kooten TG, van Goor H, Navis G, Popa ER: Bone marrow-derived myofibroblasts contribute to the renal interstitial myofibroblast population and produce procollagen I after ischemia/reperfusion in rats. J AmSoc Nephrol 18: 165-175, 2007
10. Chen G, Lin SC, Chen J, He L, Dong F, Xu J, Han S, Du J, Entman ML, Wang Y: CXCL16 recruits bone marrow-derived fibroblast precursors in renal fibrosis. J Am Soc Nephrol 22: 1876-1886, 2011
11. Bucala R, Spiegel LA, Chesney J, Hogan M, Cerami A: Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair. Mol Med 1: 71-81, 1994
12. Niedermeier M, Reich B, Rodriguez Gomez M, Denzel A, Schmidbauer K, Göbel N, Talke Y, Schweda F, Mack M: CD4+ T cells control the differentiation of Gr1+monocytes into fibrocytes. Proc Natl Acad Sci U S A 106: 17892-17897, 2009
13. Shao DD, Suresh R, Vakil V, Gomer RH, Pilling D: Pivotal Advance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation. J Leukoc Biol 83: 1323-1333, 2008
14. Haudek SB, Trial J, Xia Y, Gupta D, Pilling D, Entman ML: Fc receptor engagement mediates differentiation of cardiac fibroblast precursor cells. Proc Natl Acad Sci U S A 105: 10179-10184, 2008
15. Metz CN: Fibrocytes: A unique cell population implicated in wound healing. Cell Mol Life Sci 60: 1342-1350, 2003
16. Quan TE, Cowper S, Wu SP, Bockenstedt LK, Bucala R: Circulating fibrocytes: Collagen-secreting cells of the peripheral blood. Int J Biochem Cell Biol 36: 598-606, 2004
17. Abe R, Donnelly SC, Peng T, Bucala R, Metz CN: Peripheral blood fibrocytes: Differentiation pathway and migration to wound sites. J Immunol 166: 7556-7562, 2001
18. Cieslik KA, Taffet GE, Carlson S, Hermosillo J, Trial J, Entman ML: Immuneinflammatory dysregulation modulates the incidence of progressive fibrosis and diastolic stiffness in the aging heart. J Mol Cell Cardiol 50: 248-256, 2011
19. Tilg H, Moschen AR: Adipocytokines: Mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol 6: 772-783, 2006
20. Karbowska J, Kochan Z: Role of adiponectin in the regulation of carbohydrate and lipidmetabolism. J Physiol Pharmacol 57 [Suppl 6]: 103-113, 2006
21. Scherer PE, Williams S, Fogliano M, Baldini G, Lodish HF: A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 270: 26746-26749, 1995
22. Wolf AM, Wolf D, Avila MA, Moschen AR, Berasain C, Enrich B, Rumpold H, Tilg H: Up-regulation of the anti-inflammatory adipokine adiponectin in acute liver failure in mice. J Hepatol 44: 537-543, 2006
23. Crawford LJ, Peake R, Price S, Morris TC, Irvine AE: Adiponectin is produced by lymphocytes and is a negative regulator of granulopoiesis. J Leukoc Biol 88: 807-811, 2010
24. Katsiougiannis S, Kapsogeorgou EK, Manoussakis MN, Skopouli FN: Salivary gland epithelial cells: A new source of the immunoregulatory hormone adiponectin. Arthritis Rheum 54: 2295-2299, 2006
25. Miller M, Cho JY, Pham A, Ramsdell J, Broide DH: Adiponectin and functional adiponectin receptor 1 are expressed by airway epithelial cells in chronic obstructive pulmonary disease. J Immunol 182: 684-691, 2009
26. Becker B, Kronenberg F, Kielstein JT, Haller H, Morath C, Ritz E, Fliser D; MMKDStudyGroup: Renal insulin resistance syndrome, adiponectin and cardiovascular events in patients with kidney disease: The mild and moderate kidney disease study. J Am Soc Nephrol 16: 1091-1098, 2005
27. Stenvinkel P: Adiponectin in chronic kidney disease: A complex and context sensitive clinical situation. J Ren Nutr 21: 82-86, 2011
28. Haudek SB, Cheng J, Du J, Wang Y, Hermosillo-Rodriguez J, Trial J, Taffet GE, Entman ML: Monocytic fibroblast precursorsmediate fibrosis in angiotensin-II-induced cardiac hypertrophy. J Mol Cell Cardiol 49: 499-507, 2010
29. Gordon S, Martinez FO: Alternative activation of macrophages: Mechanism and functions. Immunity 32: 593-604, 2010
30. Ricardo SD, van Goor H, Eddy AA: Macrophage diversity in renal injury and repair. J Clin Invest 118: 3522-3530, 2008
31. Heiker JT, Kosel D, Beck-Sickinger AG: Molecularmechanisms of signal transduction via adiponectin and adiponectin receptors. Biol Chem 391: 1005-1018, 2010
32. Zhang G, Moorhead PJ, el Nahas AM: Myofibroblasts and the progression of experimental glomerulonephritis. ExpNephrol 3: 308-318, 1995
33. Roberts IS, Burrows C, Shanks JH, Venning M, McWilliam LJ: Interstitial myofibroblasts: Predictors of progression in membranous nephropathy. J Clin Pathol 50: 123-127, 1997
34. Essawy M, Soylemezoglu O, Muchaneta-Kubara EC, Shortland J, Brown CB, el Nahas AM: Myofibroblasts and the progression of diabetic nephropathy. Nephrol Dial Transplant 12: 43-50, 1997
35. Wynn TA: Cellular and molecular mechanisms of fibrosis. J Pathol 214: 199-210, 2008
36. Kisseleva T, Brenner DA: Mechanisms of fibrogenesis. Exp Biol Med (Maywood) 233: 109-122, 2008
37. Cheever AW, Williams ME, Wynn TA, Finkelman FD, Seder RA, Cox TM, Hieny S, Caspar P, Sher A: Anti-IL-4 treatment of Schistosoma mansoniinfected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis. J Immunol 153: 753-759, 1994
38. Finkelman FD, Wynn TA, Donaldson DD, Urban JF: The role of IL-13 in helminth-induced inflammation and protective immunity against nematode infections. Curr Opin Immunol 11: 420-426, 1999
39. Wynn TA, Barron L: Macrophages: Master regulators of inflammation and fibrosis. Semin Liver Dis 30: 245-257, 2010
40. Lee S, Huen S, Nishio H, Nishio S, Lee HK, Choi BS, Ruhrberg C, Cantley LG: Distinct macrophage phenotypes contribute to kidney injury and repair. J Am Soc Nephrol 22: 317-326, 2011
41. Mandal P, Pratt BT, Barnes M, McMullen MR, Nagy LE: Molecular mechanism for adiponectin-dependent M2 macrophage polarization: Link between the metabolic and innate immune activity of full-length adiponectin. J Biol Chem 286: 13460-13469, 2011
42. Ohashi K, Parker JL, Ouchi N, Higuchi A, Vita JA, Gokce N, Pedersen AA, Kalthoff C, Tullin S, Sams A, Summer R, Walsh K: Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype. J Biol Chem 285: 6153-6160, 2010
43. Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, Sugiyama T, Miyagishi M, Hara K, Tsunoda M, Murakami K, Ohteki T, Uchida S, Takekawa S, Waki H, Tsuno NH, Shibata Y, Terauchi Y, Froguel P, Tobe K, Koyasu S, Taira K, Kitamura T, Shimizu T, Nagai R, Kadowaki T: Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 423: 762-769, 2003
44. Kadowaki T, Yamauchi T: Adiponectin and adiponectin receptors. Endocr Rev 26: 439-451, 2005
45. Mao X, Kikani CK, Riojas RA, Langlais P, Wang L, Ramos FJ, Fang Q, Christ-Roberts CY, Hong JY, Kim RY, Liu F, Dong LQ: APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function. Nat Cell Biol 8: 516-523, 2006
46. Steinberg GR, Kemp BE: AMPK in health and disease. Physiol Rev 89: 1025-1078, 2009
47. Ma K, Cabrero A, Saha PK, Kojima H, Li L, Chang BH, Paul A, Chan L: Increased beta-oxidation but no insulin resistance or glucose intolerance inmice lacking adiponectin. J Biol Chem 277: 34658-34661, 2002
48. Weischenfeldt J, Porse B: Bone marrow-derived macrophages (BMM): isolation and applications. CSH Protoc, 2008: pdb prot5080, 2008