Delivery of Therapeutic Proteins via Extracellular Vesicles: Review and Potential Treatments for Parkinson’s Disease, Glioma, and Schwannoma

Cellular and Molecular Neurobiology

Volumn 36, Issue 3, 2016, Pages 417-427

  Hall, Justin ^a,b   Prabhakar, Shilpa ^b   Balaj, Leonora ^b   Lai, Charles P ^b,c   Cerione, Richard A ^a   Breakefield, Xandra O ^b,d  

^a Department of Molecular Biology and Genetics   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Exosomes; Extracellular vesicles; Glioma; Parkinson s disease; Schwannoma; Therapeutic protein delivery

Indexed keywords

ANTINEOPLASTIC AGENT; CATALASE; INTERLEUKIN 1BETA CONVERTING ENZYME; PLASMID DNA; PRODRUG; PROTEIN; THERAPEUTIC PROTEIN; UNCLASSIFIED DRUG; RECOMBINANT PROTEIN;

BLOOD BRAIN BARRIER; DRUG UPTAKE; EXOSOME; EXTRACELLULAR VESICLE THERAPEUTIC PROTEIN DELIVERY; GENE DELIVERY SYSTEM; GENE OVEREXPRESSION; GLIOMA; GLIOMA CELL; HEK293 CELL LINE; HUMAN; IMMUNOREACTIVITY; NERVE DEGENERATION; NEURILEMOMA; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; REVIEW; SCHWANN CELL; SUICIDE GENE; ANIMAL; BRAIN NEOPLASMS; DRUG DELIVERY SYSTEM; METABOLISM; NEURILEMMOMA; PATHOLOGY;

ANIMALS; BRAIN NEOPLASMS; DRUG DELIVERY SYSTEMS; EXTRACELLULAR VESICLES; GLIOMA; HUMANS; NEURILEMMOMA; PARKINSON DISEASE; RECOMBINANT PROTEINS;

EID: 84961655033     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-015-0309-0     Document Type: Review

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