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Volumn 233, Issue , 2015, Pages 73-93

Glucocorticoids and metabolic control

Author keywords

Adipose tissue; Glucocorticoid hormones; Glucocorticoid receptor; Gluconeogenesis; Lipid metabolism; Liver; Muscle; Protein metabolism

Indexed keywords

ACYL COENZYME A DEHYDROGENASE; ATROGIN 1; CARBON; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLUCOSE; GLUCOSE TRANSPORTER 4; GLYCOGEN; GLYCOGEN SYNTHASE KINASE 3; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; MUSCLE RING FINGER 1 PROTEIN; MYOSTATIN; PROTEIN KINASE B; PYRUVATE DEHYDROGENASE KINASE 4; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN; PROTEIN;

EID: 84961626030     PISSN: 01712004     EISSN: 18650325     Source Type: Book Series    
DOI: 10.1007/164_2015_1     Document Type: Article
Times cited : (81)

References (115)
  • 1
    • 84876267697 scopus 로고    scopus 로고
    • Cortisol, obesity, and the metabolic syndrome: A cross-sectional study of obese subjects and review of the literature
    • Abraham SB, Rubino D, Sinaii N, Ramsey S, Nieman LK (2013) Cortisol, obesity, and the metabolic syndrome: a cross-sectional study of obese subjects and review of the literature. Obesity 21:E105–E117.
    • (2013) Obesity , vol.21 , pp. E105-E117
    • Abraham, S.B.1    Rubino, D.2    Sinaii, N.3    Ramsey, S.4    Nieman, L.K.5
  • 2
    • 49749202480 scopus 로고
    • The synergistic effect of cortisone and insulin on lipogenesis in the perfused rat liver as studied with alpha-C14-acetate
    • Altman KI, Miller LL, Bly CG (1951) The synergistic effect of cortisone and insulin on lipogenesis in the perfused rat liver as studied with alpha-C14-acetate. Arch Biochem Biophys 31:329–331.
    • (1951) Arch Biochem Biophys , vol.31 , pp. 329-331
    • Altman, K.I.1    Miller, L.L.2    Bly, C.G.3
  • 3
    • 0020630564 scopus 로고
    • The effects of glucocorticoids on insulin-stimulated lipogenesis in primary cultures of rat hepatocytes
    • Amatruda JM, Danahy SA, Chang CL (1983) The effects of glucocorticoids on insulin-stimulated lipogenesis in primary cultures of rat hepatocytes. Biochem J 212:135–141.
    • (1983) Biochem J , vol.212 , pp. 135-141
    • Amatruda, J.M.1    Danahy, S.A.2    Chang, C.L.3
  • 4
    • 80053420374 scopus 로고    scopus 로고
    • Muscle sparing in muscle RING finger 1 null mice: Response to synthetic glucocorticoids
    • Baehr LM, Furlow JD, Bodine SC (2011) Muscle sparing in muscle RING finger 1 null mice: response to synthetic glucocorticoids. J Physiol 589:4759–4776.
    • (2011) J Physiol , vol.589 , pp. 4759-4776
    • Baehr, L.M.1    Furlow, J.D.2    Bodine, S.C.3
  • 9
    • 0030936556 scopus 로고    scopus 로고
    • Does central obesity reflect “Cushing’s disease of the omentum”?
    • Bujalska IJ, Kumar S, Stewart PM (1997) Does central obesity reflect “Cushing’s disease of the omentum”? Lancet 349:1210–1213.
    • (1997) Lancet , vol.349 , pp. 1210-1213
    • Bujalska, I.J.1    Kumar, S.2    Stewart, P.M.3
  • 12
    • 20644460348 scopus 로고    scopus 로고
    • Factors that control the tissue-specific transcription of the gene for phosphoenolpyruvate carboxykinase-C
    • Chakravarty K, Cassuto H, Reshef L, Hanson RW (2005) Factors that control the tissue-specific transcription of the gene for phosphoenolpyruvate carboxykinase-C. Crit Rev Biochem Mol Biol 40:129–154.
    • (2005) Crit Rev Biochem Mol Biol , vol.40 , pp. 129-154
    • Chakravarty, K.1    Cassuto, H.2    Reshef, L.3    Hanson, R.W.4
  • 15
    • 0020073518 scopus 로고
    • Effects of adrenalectomy and dexamethasone on hepatic lipid metabolism
    • Cole TG, Wilcox HG, Heimberg M (1982) Effects of adrenalectomy and dexamethasone on hepatic lipid metabolism. J Lipid Res 23:81–91.
    • (1982) J Lipid Res , vol.23 , pp. 81-91
    • Cole, T.G.1    Wilcox, H.G.2    Heimberg, M.3
  • 17
    • 63249134179 scopus 로고    scopus 로고
    • MAFbx/Atrogin-1 controls the activity of the initiation factor eIF3-f in skeletal muscle atrophy by targeting multiple C-terminal lysines
    • Csibi A, Leibovitch MP, Cornille K, Tintignac LA, Leibovitch SA (2009) MAFbx/Atrogin-1 controls the activity of the initiation factor eIF3-f in skeletal muscle atrophy by targeting multiple C-terminal lysines. J Biol Chem 284:4413–4421.
    • (2009) J Biol Chem , vol.284 , pp. 4413-4421
    • Csibi, A.1    Leibovitch, M.P.2    Cornille, K.3    Tintignac, L.A.4    Leibovitch, S.A.5
  • 18
    • 84928724839 scopus 로고    scopus 로고
    • Brown fat in humans: Consensus points and experimental guidelines
    • Cypess AM, Haft CR, Laughlin MR, Hu HH (2014) Brown fat in humans: consensus points and experimental guidelines. Cell Metab 20:408–415
    • (2014) Cell Metab , vol.20 , pp. 408-415
    • Cypess, A.M.1    Haft, C.R.2    Laughlin, M.R.3    Hu, H.H.4
  • 20
    • 0014404227 scopus 로고
    • The role of glucose, glucagon and glucocorticoids in the regulation of liver glycogen synthesis
    • de Wulf H, Hers HG (1968) The role of glucose, glucagon and glucocorticoids in the regulation of liver glycogen synthesis. Eur J Biochem 6:558–564.
    • (1968) Eur J Biochem , vol.6 , pp. 558-564
    • De Wulf, H.1    Hers, H.G.2
  • 21
    • 0016692353 scopus 로고
    • Modulation of the activity of insulin-dependent enzymes of lipogenesis by glucocorticoids
    • Diamant S, Shafrir E (1975) Modulation of the activity of insulin-dependent enzymes of lipogenesis by glucocorticoids. Eur J Biochem 53:541–546.
    • (1975) Eur J Biochem , vol.53 , pp. 541-546
    • Diamant, S.1    Shafrir, E.2
  • 22
    • 1642545652 scopus 로고    scopus 로고
    • Regulation of the enzymes of hepatic microsomal triacylglycerol lipolysis and re-esterification by the glucocorticoid dexamethasone
    • Dolinsky VW, Douglas DN, Lehner R, Vance DE (2004) Regulation of the enzymes of hepatic microsomal triacylglycerol lipolysis and re-esterification by the glucocorticoid dexamethasone. Biochem J 378:967–974.
    • (2004) Biochem J , vol.378 , pp. 967-974
    • Dolinsky, V.W.1    Douglas, D.N.2    Lehner, R.3    Vance, D.E.4
  • 23
    • 84874916951 scopus 로고    scopus 로고
    • Myostatin suppression of Akirin1 mediates glucocorticoidinduced satellite cell dysfunction
    • Dong Y, Pan JS, Zhang L (2013) Myostatin suppression of Akirin1 mediates glucocorticoidinduced satellite cell dysfunction. PLoS One 8:e58554.
    • (2013) Plos One , vol.8
    • Dong, Y.1    Pan, J.S.2    Zhang, L.3
  • 24
    • 0038242819 scopus 로고    scopus 로고
    • TRB3: A tribbles homolog that inhibits Akt/PKB activation by insulin in liver
    • Du K, Herzig S, Kulkarni RN, Montminy M (2003) TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science 300:1574–1577.
    • (2003) Science , vol.300 , pp. 1574-1577
    • Du, K.1    Herzig, S.2    Kulkarni, R.N.3    Montminy, M.4
  • 26
    • 0027163954 scopus 로고
    • Glucocorticoid regulation of insulin receptor and substrate IRS-1 tyrosine phosphorylation in rat skeletal muscle in vivo
    • Giorgino F, Almahfouz A, Goodyear LJ, Smith RJ (1993) Glucocorticoid regulation of insulin receptor and substrate IRS-1 tyrosine phosphorylation in rat skeletal muscle in vivo. J Clin Invest 91:2020–2030.
    • (1993) J Clin Invest , vol.91 , pp. 2020-2030
    • Giorgino, F.1    Almahfouz, A.2    Goodyear, L.J.3    Smith, R.J.4
  • 27
    • 84863281947 scopus 로고    scopus 로고
    • Angiopoietin-like 4 (Angptl4) protein is a physiological mediator of intracellular lipolysis in murine adipocytes
    • Gray NE, Lam LN, Yang K, Zhou AY, Koliwad S, Wang JC (2012) Angiopoietin-like 4 (Angptl4) protein is a physiological mediator of intracellular lipolysis in murine adipocytes. J Biol Chem 287:8444–8456.
    • (2012) J Biol Chem , vol.287 , pp. 8444-8456
    • Gray, N.E.1    Lam, L.N.2    Yang, K.3    Zhou, A.Y.4    Koliwad, S.5    Wang, J.C.6
  • 28
    • 0031033882 scopus 로고    scopus 로고
    • Dexamethasone induces posttranslational degradation of GLUT2 and inhibition of insulin secretion in isolated pancreatic beta cells. Comparison with the effects of fatty acids
    • Gremlich S, Roduit R, Thorens B (1997) Dexamethasone induces posttranslational degradation of GLUT2 and inhibition of insulin secretion in isolated pancreatic beta cells. Comparison with the effects of fatty acids. J Biol Chem 272:3216–3222.
    • (1997) J Biol Chem , vol.272 , pp. 3216-3222
    • Gremlich, S.1    Roduit, R.2    Thorens, B.3
  • 29
    • 0026762722 scopus 로고
    • Role of glucose transporters in glucocorticoid-induced insulin resistance. GLUT4 isoform in rat skeletal muscle is not decreased by dexamethasone
    • Haber RS, Weinstein SP (1992) Role of glucose transporters in glucocorticoid-induced insulin resistance. GLUT4 isoform in rat skeletal muscle is not decreased by dexamethasone. Diabetes 41:728–735.
    • (1992) Diabetes , vol.41 , pp. 728-735
    • Haber, R.S.1    Weinstein, S.P.2
  • 30
    • 33846675889 scopus 로고    scopus 로고
    • Insulin represses phosphoenolpyruvate carboxykinase gene transcription by causing the rapid disruption of an active transcription complex: A potential epigenetic effect
    • Hall RK, Wang XL, George L, Koch SR, Granner DK (2007) Insulin represses phosphoenolpyruvate carboxykinase gene transcription by causing the rapid disruption of an active transcription complex: a potential epigenetic effect. Mol Endocrinol 21:550–563.
    • (2007) Mol Endocrinol , vol.21 , pp. 550-563
    • Hall, R.K.1    Wang, X.L.2    George, L.3    Koch, S.R.4    Granner, D.K.5
  • 31
    • 0027994349 scopus 로고
    • The sphingomyelin cycle and the second messenger function of ceramide
    • Hannun YA (1994) The sphingomyelin cycle and the second messenger function of ceramide. J Biol Chem 269:3125–3128.
    • (1994) J Biol Chem , vol.269 , pp. 3125-3128
    • Hannun, Y.A.1
  • 32
    • 0030746916 scopus 로고    scopus 로고
    • Associations between pituitary-adrenocortical function and abdominal obesity, hyperinsulinaemia and dyslipidaemia in normotensive males
    • Hautanen A, Raikkonen K, Adlercreutz H (1997) Associations between pituitary-adrenocortical function and abdominal obesity, hyperinsulinaemia and dyslipidaemia in normotensive males. J Intern Med 241:451–461.
    • (1997) J Intern Med , vol.241 , pp. 451-461
    • Hautanen, A.1    Raikkonen, K.2    Adlercreutz, H.3
  • 34
    • 70349658713 scopus 로고    scopus 로고
    • Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice
    • Hu Z, Wang H, Lee IH, Du J, Mitch WE (2009) Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice. J Clin Invest 119:3059–3069.
    • (2009) J Clin Invest , vol.119 , pp. 3059-3069
    • Hu, Z.1    Wang, H.2    Lee, I.H.3    Du, J.4    Mitch, W.E.5
  • 35
    • 29644434851 scopus 로고    scopus 로고
    • The Smad6-histone deacetylase 3 complex silences the transcriptional activity of the glucocorticoid receptor: Potential clinical implications
    • Ichijo T, Voutetakis A, Cotrim AP, Bhattachryya N, Fujii M, Chrousos GP, Kino T (2005) The Smad6-histone deacetylase 3 complex silences the transcriptional activity of the glucocorticoid receptor: potential clinical implications. J Biol Chem 280:42067–42077.
    • (2005) J Biol Chem , vol.280 , pp. 42067-42077
    • Ichijo, T.1    Voutetakis, A.2    Cotrim, A.P.3    Bhattachryya, N.4    Fujii, M.5    Chrousos, G.P.6    Kino, T.7
  • 36
    • 68349159285 scopus 로고    scopus 로고
    • Conditional ablation of mediator subunit MED1 (MED1/PPARBP) gene in mouse liver attenuates glucocorticoid receptor agonist dexamethasone-induced hepatic steatosis
    • Jia Y, Viswakarma N, Fu T, Yu S, Rao MS, Borensztajn J, Reddy JK (2009) Conditional ablation of mediator subunit MED1 (MED1/PPARBP) gene in mouse liver attenuates glucocorticoid receptor agonist dexamethasone-induced hepatic steatosis. Gene Expr 14:291–306.
    • (2009) Gene Expr , vol.14 , pp. 291-306
    • Jia, Y.1    Viswakarma, N.2    Fu, T.3    Yu, S.4    Rao, M.S.5    Borensztajn, J.6    Reddy, J.K.7
  • 37
    • 84893905826 scopus 로고    scopus 로고
    • Overweight and obese children have lower cortisol levels than normal weight children
    • Kjolhede EA, Gustafsson PE, Gustafsson PA, Nelson N (2014) Overweight and obese children have lower cortisol levels than normal weight children. Acta Paediatr 103:295–299.
    • (2014) Acta Paediatr , vol.103 , pp. 295-299
    • Kjolhede, E.A.1    Gustafsson, P.E.2    Gustafsson, P.A.3    Nelson, N.4
  • 38
    • 70350008227 scopus 로고    scopus 로고
    • Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism
    • Koliwad SK, Kuo T, Shipp LE, Gray NE, Backhed F, So AY, Farese RV Jr, Wang JC (2009) Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism. J Biol Chem 284:25593–25601.
    • (2009) J Biol Chem , vol.284 , pp. 25593-25601
    • Koliwad, S.K.1    Kuo, T.2    Shipp, L.E.3    Gray, N.E.4    Backhed, F.5    So, A.Y.6    Farese, R.V.7    Wang, J.C.8
  • 40
    • 84863943516 scopus 로고    scopus 로고
    • Genome-wide analysis of glucocorticoid receptor-binding sites in myotubes identifies gene networks modulating insulin signaling
    • Kuo T, Lew MJ, Mayba O, Harris CA, Speed TP, Wang JC (2012) Genome-wide analysis of glucocorticoid receptor-binding sites in myotubes identifies gene networks modulating insulin signaling. Proc Natl Acad Sci U S A 109:11160–11165.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 11160-11165
    • Kuo, T.1    Lew, M.J.2    Mayba, O.3    Harris, C.A.4    Speed, T.P.5    Wang, J.C.6
  • 41
    • 84884532489 scopus 로고    scopus 로고
    • Metabolic functions of glucocorticoid receptor in skeletal muscle
    • Kuo T, Harris CA, Wang JC (2013) Metabolic functions of glucocorticoid receptor in skeletal muscle. Mol Cell Endocrinol 380:79–88.
    • (2013) Mol Cell Endocrinol , vol.380 , pp. 79-88
    • Kuo, T.1    Harris, C.A.2    Wang, J.C.3
  • 42
    • 1842475551 scopus 로고    scopus 로고
    • Protein kinase B-alpha inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FOXO transcription factors
    • Kwon HS, Huang B, Unterman TG, Harris RA (2004) Protein kinase B-alpha inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FOXO transcription factors. Diabetes 53:899–910.
    • (2004) Diabetes , vol.53 , pp. 899-910
    • Kwon, H.S.1    Huang, B.2    Unterman, T.G.3    Harris, R.A.4
  • 44
    • 0020516944 scopus 로고
    • On the mechanism by which glucocorticoids cause the activation of glycogen synthase in mouse and rat livers
    • Laloux M, Stalmans W, Hers HG (1983) On the mechanism by which glucocorticoids cause the activation of glycogen synthase in mouse and rat livers. Eur J Biochem 136:175–181.
    • (1983) Eur J Biochem , vol.136 , pp. 175-181
    • Laloux, M.1    Stalmans, W.2    Hers, H.G.3
  • 45
    • 0030866606 scopus 로고    scopus 로고
    • Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets
    • Lambillotte C, Gilon P, Henquin JC (1997) Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets. J Clin Invest 99:414–423.
    • (1997) J Clin Invest , vol.99 , pp. 414-423
    • Lambillotte, C.1    Gilon, P.2    Henquin, J.C.3
  • 46
    • 0025046510 scopus 로고
    • Effects of antiglucocorticoid RU 486 on development of obesity in obese fa/fa Zucker rats
    • Langley SC, York DA (1990) Effects of antiglucocorticoid RU 486 on development of obesity in obese fa/fa Zucker rats. Am J Physiol 259:R539–R544.
    • (1990) Am J Physiol , vol.259 , pp. R539-R544
    • Langley, S.C.1    York, D.A.2
  • 47
    • 0028003839 scopus 로고
    • Regulation of the peroxisome proliferator-activated receptor alpha gene by glucocorticoids
    • Lemberger T, Staels B, Saladin R, Desvergne B, Auwerx J, Wahli W (1994) Regulation of the peroxisome proliferator-activated receptor alpha gene by glucocorticoids. J Biol Chem 269:24527–24530.
    • (1994) J Biol Chem , vol.269 , pp. 24527-24530
    • Lemberger, T.1    Staels, B.2    Saladin, R.3    Desvergne, B.4    Auwerx, J.5    Wahli, W.6
  • 49
    • 0030956006 scopus 로고    scopus 로고
    • Glucocorticoids inhibit mitochondrial matrix acyl-CoA dehydrogenases and fatty acid betaoxidation
    • Letteron P, Brahimi-Bourouina N, Robin MA, Moreau A, Feldmann G, Pessayre D (1997) Glucocorticoids inhibit mitochondrial matrix acyl-CoA dehydrogenases and fatty acid betaoxidation. Am J Physiol 272:G1141–G1150.
    • (1997) Am J Physiol , vol.272 , pp. G1141-G1150
    • Letteron, P.1    Brahimi-Bourouina, N.2    Robin, M.A.3    Moreau, A.4    Feldmann, G.5    Pessayre, D.6
  • 50
    • 0031725419 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 1alpha is an accessory factor required for activation of glucose-6-phosphatase gene transcription by glucocorticoids
    • Lin B, Morris DW, Chou JY (1998) Hepatocyte nuclear factor 1alpha is an accessory factor required for activation of glucose-6-phosphatase gene transcription by glucocorticoids. DNA Cell Biol 17:967–974.
    • (1998) DNA Cell Biol , vol.17 , pp. 967-974
    • Lin, B.1    Morris, D.W.2    Chou, J.Y.3
  • 52
    • 0037225604 scopus 로고    scopus 로고
    • Adrenalectomy enhances the insulin sensitivity of muscle protein synthesis
    • Long W, Barrett EJ, Wei L, Liu Z (2003) Adrenalectomy enhances the insulin sensitivity of muscle protein synthesis. Am J Physiol Endocrinol Metab 284:E102–E109.
    • (2003) Am J Physiol Endocrinol Metab , vol.284 , pp. E102-E109
    • Long, W.1    Barrett, E.J.2    Wei, L.3    Liu, Z.4
  • 54
    • 0022475804 scopus 로고
    • Effects of dexamethasone and insulin on the synthesis of triacylglycerols and phosphatidylcholine and the secretion of very-low-density lipoproteins and lysophosphatidylcholine by monolayer cultures of rat hepatocytes
    • Mangiapane EH, Brindley DN (1986) Effects of dexamethasone and insulin on the synthesis of triacylglycerols and phosphatidylcholine and the secretion of very-low-density lipoproteins and lysophosphatidylcholine by monolayer cultures of rat hepatocytes. Biochem J 233:151–160.
    • (1986) Biochem J , vol.233 , pp. 151-160
    • Mangiapane, E.H.1    Brindley, D.N.2
  • 56
    • 54849413378 scopus 로고    scopus 로고
    • Dexamethasone and corticosterone induce similar, but not identical, muscle wasting responses in cultured L6 and C2C12 myotubes
    • Menconi M, Gonnella P, Petkova V, Lecker S, Hasselgren PO (2008) Dexamethasone and corticosterone induce similar, but not identical, muscle wasting responses in cultured L6 and C2C12 myotubes. J Cell Biochem 105:353–364.
    • (2008) J Cell Biochem , vol.105 , pp. 353-364
    • Menconi, M.1    Gonnella, P.2    Petkova, V.3    Lecker, S.4    Hasselgren, P.O.5
  • 57
    • 0021801137 scopus 로고
    • The stimulation of lipogenesis in white adipose tissue from fed rats by corticosterone
    • Minshull M, Strong CR (1985) The stimulation of lipogenesis in white adipose tissue from fed rats by corticosterone. Int J Biochem 17:529–532.
    • (1985) Int J Biochem , vol.17 , pp. 529-532
    • Minshull, M.1    Strong, C.R.2
  • 58
    • 77956105754 scopus 로고    scopus 로고
    • AMPK regulates metabolic actions of glucocorticoids by phosphorylating the glucocorticoid receptor through p38. MAPK
    • Nader N, Ng SS, Lambrou GI, Pervanidou P, Wang Y, Chrousos GP, Kino T (2010) AMPK regulates metabolic actions of glucocorticoids by phosphorylating the glucocorticoid receptor through p38. MAPK. Mol Endocrinol 24:1748–1764.
    • (2010) Mol Endocrinol , vol.24 , pp. 1748-1764
    • Nader, N.1    Ng, S.S.2    Lambrou, G.I.3    Pervanidou, P.4    Wang, Y.5    Chrousos, G.P.6    Kino, T.7
  • 59
    • 84863373226 scopus 로고    scopus 로고
    • Liver x receptors regulate the transcriptional activity of the glucocorticoid receptor: Implications for the carbohydrate metabolism
    • Nader N, Ng SS, Wang Y, Abel BS, Chrousos GP, Kino T (2012) Liver x receptors regulate the transcriptional activity of the glucocorticoid receptor: implications for the carbohydrate metabolism. PLoS One 7:e26751.
    • (2012) Plos One , vol.7
    • Nader, N.1    Ng, S.S.2    Wang, Y.3    Abel, B.S.4    Chrousos, G.P.5    Kino, T.6
  • 60
    • 0035185021 scopus 로고    scopus 로고
    • The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
    • Nakae J, Kitamura T, Silver DL, Accili D (2001) The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. J Clin Invest 108:1359–1367.
    • (2001) J Clin Invest , vol.108 , pp. 1359-1367
    • Nakae, J.1    Kitamura, T.2    Silver, D.L.3    Accili, D.4
  • 61
    • 4644237871 scopus 로고    scopus 로고
    • Metabolic adaptations to dexamethasone-induced insulin resistance in healthy volunteers
    • Nicod N, Giusti V, Besse C, Tappy L (2003) Metabolic adaptations to dexamethasone-induced insulin resistance in healthy volunteers. Obes Res 11:625–631.
    • (2003) Obes Res , vol.11 , pp. 625-631
    • Nicod, N.1    Giusti, V.2    Besse, C.3    Tappy, L.4
  • 62
    • 2542495763 scopus 로고    scopus 로고
    • Inactivation of the glucocorticoid receptor in hepatocytes leads to fasting hypoglycemia and ameliorates hyperglycemia in streptozotocin-induced diabetes mellitus
    • Opherk C, Tronche F, Kellendonk C, Kohlmuller D, Schulze A, Schmid W, Schutz G (2004) Inactivation of the glucocorticoid receptor in hepatocytes leads to fasting hypoglycemia and ameliorates hyperglycemia in streptozotocin-induced diabetes mellitus. Mol Endocrinol 18:1346–1353.
    • (2004) Mol Endocrinol , vol.18 , pp. 1346-1353
    • Opherk, C.1    Tronche, F.2    Kellendonk, C.3    Kohlmuller, D.4    Schulze, A.5    Schmid, W.6    Schutz, G.7
  • 64
    • 80054986457 scopus 로고    scopus 로고
    • The effects of glucocorticoids on adipose tissue lipid metabolism
    • Peckett AJ, Wright DC, Riddell MC (2011) The effects of glucocorticoids on adipose tissue lipid metabolism. Metabolism 60:1500–1510.
    • (2011) Metabolism , vol.60 , pp. 1500-1510
    • Peckett, A.J.1    Wright, D.C.2    Riddell, M.C.3
  • 68
    • 84907505130 scopus 로고    scopus 로고
    • Functional and molecular aspects of glucocorticoids in the endocrine pancreas and glucose homeostasis
    • Magdeldin S, InTech, Rijeka
    • Rafacho A, Boschero AC, Ortsäter H (2012) Functional and molecular aspects of glucocorticoids in the endocrine pancreas and glucose homeostasis. In: Magdeldin S (ed) State of the art of therapeutic endocrinology. InTech, Rijeka
    • (2012) State of the Art of Therapeutic Endocrinology
    • Rafacho, A.1    Boschero, A.C.2    Ortsäter, H.3
  • 69
    • 33745319608 scopus 로고    scopus 로고
    • Dexamethasone induces cell death in insulin-secreting cells, an effect reversed by exendin-4
    • Ranta F, Avram D, Berchtold S, Dufer M, Drews G, Lang F, Ullrich S (2006) Dexamethasone induces cell death in insulin-secreting cells, an effect reversed by exendin-4. Diabetes 55:1380–1390.
    • (2006) Diabetes , vol.55 , pp. 1380-1390
    • Ranta, F.1    Avram, D.2    Berchtold, S.3    Dufer, M.4    Drews, G.5    Lang, F.6    Ullrich, S.7
  • 71
    • 84862579644 scopus 로고    scopus 로고
    • Involvement of thioredoxin-interacting protein (TXNIP) in glucocorticoid-mediated beta cell death
    • Reich E, Tamary A, Sionov RV, Melloul D (2012) Involvement of thioredoxin-interacting protein (TXNIP) in glucocorticoid-mediated beta cell death. Diabetologia 55:1048–1057.
    • (2012) Diabetologia , vol.55 , pp. 1048-1057
    • Reich, E.1    Tamary, A.2    Sionov, R.V.3    Melloul, D.4
  • 72
    • 84867825620 scopus 로고    scopus 로고
    • Dual role for glucocorticoids in cardiomyocyte hypertrophy and apoptosis
    • Ren R, Oakley RH, Cruz-Topete D, Cidlowski JA (2012) Dual role for glucocorticoids in cardiomyocyte hypertrophy and apoptosis. Endocrinology 153:5346–5360.
    • (2012) Endocrinology , vol.153 , pp. 5346-5360
    • Ren, R.1    Oakley, R.H.2    Cruz-Topete, D.3    Cidlowski, J.A.4
  • 75
    • 0242349197 scopus 로고    scopus 로고
    • Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): Requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis
    • Rhee J, Inoue Y, Yoon JC, Puigserver P, Fan M, Gonzalez FJ, Spiegelman BM (2003) Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis. Proc Natl Acad Sci U S A 100:4012–4017.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 4012-4017
    • Rhee, J.1    Inoue, Y.2    Yoon, J.C.3    Puigserver, P.4    Fan, M.5    Gonzalez, F.J.6    Spiegelman, B.M.7
  • 77
    • 26244462447 scopus 로고    scopus 로고
    • Glucocorticoid-induced insulin resistance in skeletal muscles: Defects in insulin signalling and the effects of a selective glycogen synthase kinase-3 inhibitor
    • Ruzzin J, Wagman AS, Jensen J (2005) Glucocorticoid-induced insulin resistance in skeletal muscles: defects in insulin signalling and the effects of a selective glycogen synthase kinase-3 inhibitor. Diabetologia 48:2119–2130.
    • (2005) Diabetologia , vol.48 , pp. 2119-2130
    • Ruzzin, J.1    Wagman, A.S.2    Jensen, J.3
  • 78
    • 0027489828 scopus 로고
    • Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats
    • Saad MJ, Folli F, Kahn JA, Kahn CR (1993) Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats. J Clin Invest 92:2065–2072.
    • (1993) J Clin Invest , vol.92 , pp. 2065-2072
    • Saad, M.J.1    Folli, F.2    Kahn, J.A.3    Kahn, C.R.4
  • 81
    • 0036810356 scopus 로고    scopus 로고
    • Mechanisms involved in the side effects of glucocorticoids
    • Schacke H, Docke WD, Asadullah K (2002) Mechanisms involved in the side effects of glucocorticoids. Pharmacol Ther 96:23–43.
    • (2002) Pharmacol Ther , vol.96 , pp. 23-43
    • Schacke, H.1    Docke, W.D.2    Asadullah, K.3
  • 82
    • 42449133390 scopus 로고    scopus 로고
    • Mechanisms of glucocorticoid-induced myopathy
    • Schakman O, Gilson H, Thissen JP (2008) Mechanisms of glucocorticoid-induced myopathy. J Endocrinol 197:1–10.
    • (2008) J Endocrinol , vol.197 , pp. 1-10
    • Schakman, O.1    Gilson, H.2    Thissen, J.P.3
  • 83
    • 85047683614 scopus 로고    scopus 로고
    • Minireview: 11beta-hydroxysteroid dehydrogenase type 1–a tissuespecific amplifier of glucocorticoid action
    • Seckl JR, Walker BR (2001) Minireview: 11beta-hydroxysteroid dehydrogenase type 1–a tissuespecific amplifier of glucocorticoid action. Endocrinology 142:1371–1376.
    • (2001) Endocrinology , vol.142 , pp. 1371-1376
    • Seckl, J.R.1    Walker, B.R.2
  • 84
    • 2342427536 scopus 로고    scopus 로고
    • Glucocorticoids and 11betahydroxysteroid dehydrogenase in adipose tissue
    • Seckl JR, Morton NM, Chapman KE, Walker BR (2004) Glucocorticoids and 11betahydroxysteroid dehydrogenase in adipose tissue. Recent Prog Horm Res 59:359–393.
    • (2004) Recent Prog Horm Res , vol.59 , pp. 359-393
    • Seckl, J.R.1    Morton, N.M.2    Chapman, K.E.3    Walker, B.R.4
  • 85
    • 59449084854 scopus 로고    scopus 로고
    • The angiopoietin-like proteins ANGPTL3 and ANGPTL4 inhibit lipoprotein lipase activity through distinct mechanisms
    • Shan L, Yu XC, Liu Z, Hu Y, Sturgis LT, Miranda ML, Liu Q (2009) The angiopoietin-like proteins ANGPTL3 and ANGPTL4 inhibit lipoprotein lipase activity through distinct mechanisms. J Biol Chem 284:1419–1424.
    • (2009) J Biol Chem , vol.284 , pp. 1419-1424
    • Shan, L.1    Yu, X.C.2    Liu, Z.3    Hu, Y.4    Sturgis, L.T.5    Miranda, M.L.6    Liu, Q.7
  • 87
    • 0027964645 scopus 로고
    • Normal differentiation of rat brown adipocytes in primary culture judged by their expressions of uncoupling protein and the physiological isoform of glucose-transporter
    • Shima A, Shinohara Y, Doi K, Terada H (1994) Normal differentiation of rat brown adipocytes in primary culture judged by their expressions of uncoupling protein and the physiological isoform of glucose-transporter. Biochim Biophys Acta-Mol Cell Res 1223:1–8.
    • (1994) Biochim Biophys Acta-Mol Cell Res , vol.1223 , pp. 1-8
    • Shima, A.1    Shinohara, Y.2    Doi, K.3    Terada, H.4
  • 89
    • 0028037616 scopus 로고
    • Hormonal regulation of hormone-sensitive lipase activity and mRNA levels in isolated rat adipocytes
    • Slavin BG, Ong JM, Kern PA (1994) Hormonal regulation of hormone-sensitive lipase activity and mRNA levels in isolated rat adipocytes. J Lipid Res 35:1535–1541.
    • (1994) J Lipid Res , vol.35 , pp. 1535-1541
    • Slavin, B.G.1    Ong, J.M.2    Kern, P.A.3
  • 91
    • 0034713765 scopus 로고    scopus 로고
    • Glucocorticoids inhibit the transcriptional response of the uncoupling protein-1 gene to adrenergic stimulation in a brown adipose cell line
    • Soumano K, Desbiens S, Rabelo R, Bakopanos E, Camirand A, Silva JE (2000) Glucocorticoids inhibit the transcriptional response of the uncoupling protein-1 gene to adrenergic stimulation in a brown adipose cell line. Mol Cell Endocrinol 165:7–15.
    • (2000) Mol Cell Endocrinol , vol.165 , pp. 7-15
    • Soumano, K.1    Desbiens, S.2    Rabelo, R.3    Bakopanos, E.4    Camirand, A.5    Silva, J.E.6
  • 94
    • 0029978515 scopus 로고    scopus 로고
    • Gender differences in the associations between cortisol and insulin in healthy subjects
    • Stolk RP, Lamberts SW, de Jong FH, Pols HA, Grobbee DE (1996) Gender differences in the associations between cortisol and insulin in healthy subjects. J Endocrinol 149:313–318.
    • (1996) J Endocrinol , vol.149 , pp. 313-318
    • Stolk, R.P.1    Lamberts, S.W.2    De Jong, F.H.3    Pols, H.A.4    Grobbee, D.E.5
  • 95
    • 0028873134 scopus 로고
    • Corticosterone decreases nonshivering thermogenesis and increases lipid storage in brown adipose tissue
    • Strack AM, Bradbury MJ, Dallman MF (1995) Corticosterone decreases nonshivering thermogenesis and increases lipid storage in brown adipose tissue. Am J Physiol 268:R183–R191.
    • (1995) Am J Physiol , vol.268 , pp. R183-R191
    • Strack, A.M.1    Bradbury, M.J.2    Dallman, M.F.3
  • 96
    • 0037404976 scopus 로고    scopus 로고
    • Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs
    • Sugden MC, Holness MJ (2003) Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs. Am J Physiol Endocrinol Metab 284:E855–E862.
    • (2003) Am J Physiol Endocrinol Metab , vol.284 , pp. E855-E862
    • Sugden, M.C.1    Holness, M.J.2
  • 97
    • 0020565483 scopus 로고
    • Plasma lipoproteins, lipolytic enzymes, and very low density lipoprotein triglyceride turnover in Cushing’s syndrome
    • Taskinen MR, Nikkila EA, Pelkonen R, Sane T (1983) Plasma lipoproteins, lipolytic enzymes, and very low density lipoprotein triglyceride turnover in Cushing’s syndrome. J Clin Endocrinol Metab 57:619–626.
    • (1983) J Clin Endocrinol Metab , vol.57 , pp. 619-626
    • Taskinen, M.R.1    Nikkila, E.A.2    Pelkonen, R.3    Sane, T.4
  • 103
    • 8744297386 scopus 로고    scopus 로고
    • Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: Ectopic expression of desnutrin increases triglyceride hydrolysis
    • Villena JA, Roy S, Sarkadi-Nagy E, Kim KH, Sul HS (2004) Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis. J Biol Chem 279:47066–47075.
    • (2004) J Biol Chem , vol.279 , pp. 47066-47075
    • Villena, J.A.1    Roy, S.2    Sarkadi-Nagy, E.3    Kim, K.H.4    Sul, H.S.5
  • 104
    • 0016605028 scopus 로고
    • Hormonal regulation of fatty acid synthetase, acetyl-CoA carboxylase and fatty acid synthesis in mammalian adipose tissue and liver
    • Volpe JJ, Marasa JC (1975) Hormonal regulation of fatty acid synthetase, acetyl-CoA carboxylase and fatty acid synthesis in mammalian adipose tissue and liver. Biochim Biophys Acta 380:454–472.
    • (1975) Biochim Biophys Acta , vol.380 , pp. 454-472
    • Volpe, J.J.1    Marasa, J.C.2
  • 106
    • 4544264010 scopus 로고    scopus 로고
    • The synergistic effect of dexamethasone and all-trans-retinoic acid on hepatic phosphoenolpyruvate carboxykinase gene expression involves the coactivator p300
    • Wang XL, Herzog B, Waltner-Law M, Hall RK, Shiota M, Granner DK (2004) The synergistic effect of dexamethasone and all-trans-retinoic acid on hepatic phosphoenolpyruvate carboxykinase gene expression involves the coactivator p300. J Biol Chem 279:34191–34200.
    • (2004) J Biol Chem , vol.279 , pp. 34191-34200
    • Wang, X.L.1    Herzog, B.2    Waltner-Law, M.3    Hall, R.K.4    Shiota, M.5    Granner, D.K.6
  • 107
    • 33846007729 scopus 로고    scopus 로고
    • Dexamethasone represses signaling through the mammalian target of rapamycin in muscle cells by enhancing expression of REDD1
    • Wang H, Kubica N, Ellisen LW, Jefferson LS, Kimball SR (2006) Dexamethasone represses signaling through the mammalian target of rapamycin in muscle cells by enhancing expression of REDD1. J Biol Chem 281:39128–39134.
    • (2006) J Biol Chem , vol.281 , pp. 39128-39134
    • Wang, H.1    Kubica, N.2    Ellisen, L.W.3    Jefferson, L.S.4    Kimball, S.R.5
  • 108
    • 84861118898 scopus 로고    scopus 로고
    • A cellautonomous role for the glucocorticoid receptor in skeletal muscle atrophy induced by systemic glucocorticoid exposure
    • Watson ML, Baehr LM, Reichardt HM, Tuckermann JP, Bodine SC, Furlow JD (2012) A cellautonomous role for the glucocorticoid receptor in skeletal muscle atrophy induced by systemic glucocorticoid exposure. Am J Physiol Endocrinol Metab 302:E1210–E1220.
    • (2012) Am J Physiol Endocrinol Metab , vol.302 , pp. E1210-E1220
    • Watson, M.L.1    Baehr, L.M.2    Reichardt, H.M.3    Tuckermann, J.P.4    Bodine, S.C.5    Furlow, J.D.6
  • 109
    • 0028933938 scopus 로고
    • Glucocorticoid-induced insulin resistance: Dexamethasone inhibits the activation of glucose transport in rat skeletal muscle by both insulin-and non-insulin-related stimuli
    • Weinstein SP, Paquin T, Pritsker A, Haber RS (1995) Glucocorticoid-induced insulin resistance: dexamethasone inhibits the activation of glucose transport in rat skeletal muscle by both insulin-and non-insulin-related stimuli. Diabetes 44:441–445.
    • (1995) Diabetes , vol.44 , pp. 441-445
    • Weinstein, S.P.1    Paquin, T.2    Pritsker, A.3    Haber, R.S.4
  • 110
    • 0031885920 scopus 로고    scopus 로고
    • Dexamethasone inhibits insulinstimulated recruitment of GLUT4 to the cell surface in rat skeletal muscle
    • Weinstein SP, Wilson CM, Pritsker A, Cushman SW (1998) Dexamethasone inhibits insulinstimulated recruitment of GLUT4 to the cell surface in rat skeletal muscle. Metabolism 47:3–6.
    • (1998) Metabolism , vol.47 , pp. 3-6
    • Weinstein, S.P.1    Wilson, C.M.2    Pritsker, A.3    Cushman, S.W.4
  • 111
    • 67749088181 scopus 로고    scopus 로고
    • Direct effect of glucocorticoids on lipolysis in adipocytes
    • Xu C, He J, Jiang H, Zu L, Zhai W, Pu S, Xu G (2009) Direct effect of glucocorticoids on lipolysis in adipocytes. Mol Endocrinol 23:1161–1170.
    • (2009) Mol Endocrinol , vol.23 , pp. 1161-1170
    • Xu, C.1    He, J.2    Jiang, H.3    Zu, L.4    Zhai, W.5    Pu, S.6    Xu, G.7
  • 114
    • 78650882261 scopus 로고    scopus 로고
    • Genome-wide analysis of glucocorticoid receptor binding regions in adipocytes reveal gene network involved in triglyceride homeostasis
    • Yu CY, Mayba O, Lee JV, Tran J, Harris C, Speed TP, Wang JC (2010) Genome-wide analysis of glucocorticoid receptor binding regions in adipocytes reveal gene network involved in triglyceride homeostasis. PLoS One 5:e15188.
    • (2010) Plos One , vol.5
    • Yu, C.Y.1    Mayba, O.2    Lee, J.V.3    Tran, J.4    Harris, C.5    Speed, T.P.6    Wang, J.C.7
  • 115
    • 0018120430 scopus 로고
    • Some effects of adrenalectomy in the fatty rat
    • Yukimura Y, Bray GA, Wolfsen AR (1978) Some effects of adrenalectomy in the fatty rat. Endocrinology 103:1924–1928
    • (1978) Endocrinology , vol.103 , pp. 1924-1928
    • Yukimura, Y.1    Bray, G.A.2    Wolfsen, A.R.3


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