-
1
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D, Weinberg RA: Hallmarks of cancer: the next generation. Cell. 2011, 144 (5): 646-674. 10.1016/j.cell.2011.02.013.
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
27644476963
-
Review article: diabetes, genetics and ethnicity
-
Carulli L, Rondinella S, Lombardini S, Canedi I, Loria P, Carulli N: Review article: diabetes, genetics and ethnicity. Alimentary pharmacology & therapeutics. 2005, 22 (Suppl 2): 16-19.
-
(2005)
Alimentary pharmacology & therapeutics
, vol.22
, pp. 16-19
-
-
Carulli, L.1
Rondinella, S.2
Lombardini, S.3
Canedi, I.4
Loria, P.5
Carulli, N.6
-
3
-
-
78049494417
-
Genetics in schizophrenia: where are we and what next?
-
Tiwari AK, Zai CC, Muller DJ, Kennedy JL: Genetics in schizophrenia: where are we and what next?. Dialogues in clinical neuroscience. 2010, 12 (3): 289-303.
-
(2010)
Dialogues in clinical neuroscience
, vol.12
, Issue.3
, pp. 289-303
-
-
Tiwari, A.K.1
Zai, C.C.2
Muller, D.J.3
Kennedy, J.L.4
-
4
-
-
0346274979
-
New methods for finding disease-susceptibility genes: impact and potential
-
McCarthy MI, Smedley D, Hide W: New methods for finding disease-susceptibility genes: impact and potential. Genome biology. 2003, 4 (10): 119. 10.1186/gb-2003-4-10-119.
-
(2003)
Genome biology
, vol.4
, Issue.10
, pp. 119.
-
-
McCarthy, M.I.1
Smedley, D.2
Hide, W.3
-
5
-
-
0037146578
-
Finding genes that underlie complex traits
-
Glazier AM, Nadeau JH, Aitman TJ: Finding genes that underlie complex traits. Science. 2002, 298 (5602): 2345-2349. 10.1126/science.1076641.
-
(2002)
Science
, vol.298
, Issue.5602
, pp. 2345-2349
-
-
Glazier, A.M.1
Nadeau, J.H.2
Aitman, T.J.3
-
6
-
-
33748092354
-
Prevalence and predictors of BRCA1 and BRCA2 mutations in a population-based study of breast cancer in white and black American women ages 35 to 64 years
-
Malone KE, Daling JR, Doody DR, Hsu L, Bernstein L, Coates RJ, Marchbanks PA, Simon MS, McDonald JA, Norman SA, et al: Prevalence and predictors of BRCA1 and BRCA2 mutations in a population-based study of breast cancer in white and black American women ages 35 to 64 years. Cancer research. 2006, 66 (16): 8297-8308. 10.1158/0008-5472.CAN-06-0503.
-
(2006)
Cancer research
, vol.66
, Issue.16
, pp. 8297-8308
-
-
Malone, K.E.1
Daling, J.R.2
Doody, D.R.3
Hsu, L.4
Bernstein, L.5
Coates, R.J.6
Marchbanks, P.A.7
Simon, M.S.8
McDonald, J.A.9
Norman, S.A.10
-
7
-
-
18344412542
-
BRCA1 and BRCA2 mutations in a population-based study of male breast cancer
-
Basham VM, Lipscombe JM, Ward JM, Gayther SA, Ponder BA, Easton DF, Pharoah PD: BRCA1 and BRCA2 mutations in a population-based study of male breast cancer. Breast cancer research: BCR. 2002, 4 (1): R2. 10.1186/bcr419.
-
(2002)
Breast cancer research: BCR
, vol.4
, Issue.1
-
-
Basham, V.M.1
Lipscombe, J.M.2
Ward, J.M.3
Gayther, S.A.4
Ponder, B.A.5
Easton, D.F.6
Pharoah, P.D.7
-
8
-
-
78649662629
-
The role of BRCA mutation testing in determining breast cancer therapy
-
Trainer AH, Lewis CR, Tucker K, Meiser B, Friedlander M, Ward RL: The role of BRCA mutation testing in determining breast cancer therapy. Nature reviews Clinical oncology. 2010, 7 (12): 708-717. 10.1038/nrclinonc.2010.175.
-
(2010)
Nature reviews Clinical oncology
, vol.7
, Issue.12
, pp. 708-717
-
-
Trainer, A.H.1
Lewis, C.R.2
Tucker, K.3
Meiser, B.4
Friedlander, M.5
Ward, R.L.6
-
9
-
-
75749097005
-
Trastuzumab: A review of its use as adjuvant treatment in human epidermal growth factor receptor 2 (HER2)-positive early breast cancer
-
Garnock-Jones KP, Keating GM, Scott LJ: Trastuzumab: A review of its use as adjuvant treatment in human epidermal growth factor receptor 2 (HER2)-positive early breast cancer. Drugs. 2010, 70 (2): 215-239. 10.2165/11203700-000000000-00000.
-
(2010)
Drugs
, vol.70
, Issue.2
, pp. 215-239
-
-
Garnock-Jones, K.P.1
Keating, G.M.2
Scott, L.J.3
-
10
-
-
79953834860
-
Serum HER2 as a response indicator to various chemotherapeutic agents in tissue HER2 positive metastatic breast cancer
-
Kong SY, Lee do H, Lee ES, Park S, Lee KS, Ro J: Serum HER2 as a response indicator to various chemotherapeutic agents in tissue HER2 positive metastatic breast cancer. Cancer research and treatment: official journal of Korean Cancer Association. 2006, 38 (1): 35-39. 10.4143/crt.2006.38.1.35.
-
(2006)
Cancer research and treatment: official journal of Korean Cancer Association
, vol.38
, Issue.1
, pp. 35-39
-
-
Kong, S.Y.1
Lee do, H.2
Lee, E.S.3
Park, S.4
Lee, K.S.5
Ro, J.6
-
11
-
-
33645128686
-
Human monogenic disorders - a source of novel drug targets
-
Brinkman RR, Dube MP, Rouleau GA, Orr AC, Samuels ME: Human monogenic disorders - a source of novel drug targets. Nature reviews Genetics. 2006, 7 (4): 249-260. 10.1038/nrg1828.
-
(2006)
Nature reviews Genetics
, vol.7
, Issue.4
, pp. 249-260
-
-
Brinkman, R.R.1
Dube, M.P.2
Rouleau, G.A.3
Orr, A.C.4
Samuels, M.E.5
-
12
-
-
84871901456
-
Objective assessment of cancer genes for drug discovery
-
Patel MN, Halling-Brown MD, Tym JE, Workman P, Al-Lazikani B: Objective assessment of cancer genes for drug discovery. Nature reviews Drug discovery. 2013, 12 (1): 35-50.
-
(2013)
Nature reviews Drug discovery
, vol.12
, Issue.1
, pp. 35-50
-
-
Patel, M.N.1
Halling-Brown, M.D.2
Tym, J.E.3
Workman, P.4
Al-Lazikani, B.5
-
13
-
-
84859638338
-
Use of genome-wide association studies for drug repositioning
-
Sanseau P, Agarwal P, Barnes MR, Pastinen T, Richards JB, Cardon LR, Mooser V: Use of genome-wide association studies for drug repositioning. Nature biotechnology. 2012, 30 (4): 317-320. 10.1038/nbt.2151.
-
(2012)
Nature biotechnology
, vol.30
, Issue.4
, pp. 317-320
-
-
Sanseau, P.1
Agarwal, P.2
Barnes, M.R.3
Pastinen, T.4
Richards, J.B.5
Cardon, L.R.6
Mooser, V.7
-
14
-
-
84880557325
-
Genomic medicine: a decade of successes, challenges, and opportunities
-
McCarthy JJ, McLeod HL, Ginsburg GS: Genomic medicine: a decade of successes, challenges, and opportunities. Science translational medicine. 2013, 5 (189): 189sr184
-
(2013)
Science translational medicine
, vol.5
, Issue.189
, pp. 189sr184
-
-
McCarthy, J.J.1
McLeod, H.L.2
Ginsburg, G.S.3
-
15
-
-
13144306071
-
Genome-wide association studies for common diseases and complex traits
-
Hirschhorn JN, Daly MJ: Genome-wide association studies for common diseases and complex traits. Nature reviews Genetics. 2005, 6 (2): 95-108. 10.1038/nrg1521.
-
(2005)
Nature reviews Genetics
, vol.6
, Issue.2
, pp. 95-108
-
-
Hirschhorn, J.N.1
Daly, M.J.2
-
16
-
-
42349112088
-
Genome-wide association studies for complex traits: consensus, uncertainty and challenges
-
McCarthy MI, Abecasis GR, Cardon LR, Goldstein DB, Little J, Ioannidis JP, Hirschhorn JN: Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nature reviews Genetics. 2008, 9 (5): 356-369. 10.1038/nrg2344.
-
(2008)
Nature reviews Genetics
, vol.9
, Issue.5
, pp. 356-369
-
-
McCarthy, M.I.1
Abecasis, G.R.2
Cardon, L.R.3
Goldstein, D.B.4
Little, J.5
Ioannidis, J.P.6
Hirschhorn, J.N.7
-
17
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, Collins FS, Manolio TA: Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proceedings of the National Academy of Sciences of the United States of America. 2009, 106 (23): 9362-9367. 10.1073/pnas.0903103106.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.23
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
Collins, F.S.6
Manolio, T.A.7
-
18
-
-
78651287426
-
DrugBank 3.0: a comprehensive resource for 'omics' research on drugs.
-
39 Database
-
Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, et al: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic acids research. 2011, D1035-1041. 39 Database
-
(2011)
Nucleic acids research.
, pp. D1035-D1041
-
-
Knox, C.1
Law, V.2
Jewison, T.3
Liu, P.4
Ly, S.5
Frolkis, A.6
Pon, A.7
Banco, K.8
Mak, C.9
Neveu, V.10
-
19
-
-
0036088113
-
PharmGKB: the Pharmacogenetics Knowledge Base
-
Hewett M, Oliver DE, Rubin DL, Easton KL, Stuart JM, Altman RB, Klein TE: PharmGKB: the Pharmacogenetics Knowledge Base. Nucleic acids research. 2002, 30 (1): 163-165. 10.1093/nar/30.1.163.
-
(2002)
Nucleic acids research
, vol.30
, Issue.1
, pp. 163-165
-
-
Hewett, M.1
Oliver, D.E.2
Rubin, D.L.3
Easton, K.L.4
Stuart, J.M.5
Altman, R.B.6
Klein, T.E.7
-
20
-
-
78650373804
-
Network medicine: a network-based approach to human disease
-
Barabasi AL, Gulbahce N, Loscalzo J: Network medicine: a network-based approach to human disease. Nature reviews Genetics. 2011, 12 (1): 56-68. 10.1038/nrg2918.
-
(2011)
Nature reviews Genetics
, vol.12
, Issue.1
, pp. 56-68
-
-
Barabasi, A.L.1
Gulbahce, N.2
Loscalzo, J.3
-
21
-
-
54249155522
-
Network pharmacology: the next paradigm in drug discovery
-
Hopkins AL: Network pharmacology: the next paradigm in drug discovery. Nature chemical biology. 2008, 4 (11): 682-690. 10.1038/nchembio.118.
-
(2008)
Nature chemical biology
, vol.4
, Issue.11
, pp. 682-690
-
-
Hopkins, A.L.1
-
22
-
-
84878889476
-
A vertex similarity-based framework to discover and rank orphan disease-related genes
-
Zhu C, Kushwaha A, Berman K, Jegga AG: A vertex similarity-based framework to discover and rank orphan disease-related genes. BMC systems biology. 2012, 6 (Suppl 3): S8. 10.1186/1752-0509-6-S3-S8.
-
(2012)
BMC systems biology
, vol.6
, pp. S8.
-
-
Zhu, C.1
Kushwaha, A.2
Berman, K.3
Jegga, A.G.4
-
23
-
-
84922005241
-
Prioritization of orphan disease-causing genes using topological feature and GO similarity between proteins in interaction networks
-
Li M, Li Q, Ganegoda GU, Wang J, Wu F, Pan Y: Prioritization of orphan disease-causing genes using topological feature and GO similarity between proteins in interaction networks. Science China Life sciences. 2014, 57 (11): 1064-1071. 10.1007/s11427-014-4747-6.
-
(2014)
Science China Life sciences
, vol.57
, Issue.11
, pp. 1064-1071
-
-
Li, M.1
Li, Q.2
Ganegoda, G.U.3
Wang, J.4
Wu, F.5
Pan, Y.6
-
24
-
-
0742305866
-
Network biology: understanding the cell's functional organization
-
Barabasi AL, Oltvai ZN: Network biology: understanding the cell's functional organization. Nature reviews Genetics. 2004, 5 (2): 101-113. 10.1038/nrg1272.
-
(2004)
Nature reviews Genetics
, vol.5
, Issue.2
, pp. 101-113
-
-
Barabasi, A.L.1
Oltvai, Z.N.2
-
25
-
-
78649682830
-
A comparative study of cancer proteins in the human protein-protein interaction network
-
Sun J, Zhao Z: A comparative study of cancer proteins in the human protein-protein interaction network. BMC Genomics. 2010, 11 (Suppl 3): S5. 10.1186/1471-2164-11-S3-S5.
-
(2010)
BMC Genomics
, vol.11
, pp. S5
-
-
Sun, J.1
Zhao, Z.2
-
26
-
-
84255194444
-
Integration of breast cancer gene signatures based on graph centrality
-
Wang J, Chen G, Li M, Pan Y: Integration of breast cancer gene signatures based on graph centrality. BMC systems biology. 2011, 5 (Suppl 3): S10. 10.1186/1752-0509-5-S3-S10.
-
(2011)
BMC systems biology
, vol.5
, pp. S10
-
-
Wang, J.1
Chen, G.2
Li, M.3
Pan, Y.4
-
27
-
-
84891790401
-
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations.
-
42 Database
-
Welter D, MacArthur J, Morales J, Burdett T, Hall P, Junkins H, Klemm A, Flicek P, Manolio T, Hindorff L, et al: The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic acids research. 2014, D1001-1006. 42 Database
-
(2014)
Nucleic acids research.
, pp. D1001-D1006
-
-
Welter, D.1
MacArthur, J.2
Morales, J.3
Burdett, T.4
Hall, P.5
Junkins, H.6
Klemm, A.7
Flicek, P.8
Manolio, T.9
Hindorff, L.10
-
28
-
-
39649108872
-
Genome-wide significance for dense SNP and resequencing data
-
Hoggart CJ, Clark TG, De Iorio M, Whittaker JC, Balding DJ: Genome-wide significance for dense SNP and resequencing data. Genetic epidemiology. 2008, 32 (2): 179-185. 10.1002/gepi.20292.
-
(2008)
Genetic epidemiology
, vol.32
, Issue.2
, pp. 179-185
-
-
Hoggart, C.J.1
Clark, T.G.2
De Iorio, M.3
Whittaker, J.C.4
Balding, D.J.5
-
29
-
-
34247548755
-
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24
-
Yeager M, Orr N, Hayes RB, Jacobs KB, Kraft P, Wacholder S, Minichiello MJ, Fearnhead P, Yu K, Chatterjee N, et al: Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nature genetics. 2007, 39 (5): 645-649. 10.1038/ng2022.
-
(2007)
Nature genetics
, vol.39
, Issue.5
, pp. 645-649
-
-
Yeager, M.1
Orr, N.2
Hayes, R.B.3
Jacobs, K.B.4
Kraft, P.5
Wacholder, S.6
Minichiello, M.J.7
Fearnhead, P.8
Yu, K.9
Chatterjee, N.10
-
30
-
-
23144464901
-
WebGestalt: an integrated system for exploring gene sets in various biological contexts.
-
33 Web Server
-
Zhang B, Kirov S, Snoddy J: WebGestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic acids research. 2005, W741-748. 33 Web Server
-
(2005)
Nucleic acids research.
, pp. W741-748
-
-
Zhang, B.1
Kirov, S.2
Snoddy, J.3
-
31
-
-
84862160806
-
PINA v2.0: mining interactome modules.
-
40 Database
-
Cowley MJ, Pinese M, Kassahn KS, Waddell N, Pearson JV, Grimmond SM, Biankin AV, Hautaniemi S, Wu J: PINA v2.0: mining interactome modules. Nucleic acids research. 2012, D862-865. 40 Database
-
(2012)
Nucleic acids research.
, pp. D862-D865
-
-
Cowley, M.J.1
Pinese, M.2
Kassahn, K.S.3
Waddell, N.4
Pearson, J.V.5
Grimmond, S.M.6
Biankin, A.V.7
Hautaniemi, S.8
Wu, J.9
-
32
-
-
0034721164
-
Error and attack tolerance of complex networks
-
Albert R, Jeong H, Barabasi AL: Error and attack tolerance of complex networks. Nature. 2000, 406 (6794): 378-382. 10.1038/35019019.
-
(2000)
Nature
, vol.406
, Issue.6794
, pp. 378-382
-
-
Albert, R.1
Jeong, H.2
Barabasi, A.L.3
-
33
-
-
59849125136
-
Dynamic modularity in protein interaction networks predicts breast cancer outcome
-
Taylor IW, Linding R, Warde-Farley D, Liu Y, Pesquita C, Faria D, Bull S, Pawson T, Morris Q, Wrana JL: Dynamic modularity in protein interaction networks predicts breast cancer outcome. Nature biotechnology. 2009, 27 (2): 199-204. 10.1038/nbt.1522.
-
(2009)
Nature biotechnology
, vol.27
, Issue.2
, pp. 199-204
-
-
Taylor, I.W.1
Linding, R.2
Warde-Farley, D.3
Liu, Y.4
Pesquita, C.5
Faria, D.6
Bull, S.7
Pawson, T.8
Morris, Q.9
Wrana, J.L.10
-
34
-
-
79151475165
-
Immunometabolism: an emerging frontier
-
Mathis D, Shoelson SE: Immunometabolism: an emerging frontier. Nature reviews Immunology. 2011, 11 (2): 81. 10.1038/nri2922.
-
(2011)
Nature reviews Immunology
, vol.11
, Issue.2
, pp. 81.
-
-
Mathis, D.1
Shoelson, S.E.2
-
35
-
-
77951069805
-
Sympathetic nervous system overactivity and its role in the development of cardiovascular disease
-
Malpas SC: Sympathetic nervous system overactivity and its role in the development of cardiovascular disease. Physiological reviews. 2010, 90 (2): 513-557. 10.1152/physrev.00007.2009.
-
(2010)
Physiological reviews
, vol.90
, Issue.2
, pp. 513-557
-
-
Malpas, S.C.1
-
36
-
-
33748776056
-
Metabolic syndrome and risk of cardiovascular disease: a meta-analysis
-
Galassi A, Reynolds K, He J: Metabolic syndrome and risk of cardiovascular disease: a meta-analysis. The American journal of medicine. 2006, 119 (10): 812-819. 10.1016/j.amjmed.2006.02.031.
-
(2006)
The American journal of medicine
, vol.119
, Issue.10
, pp. 812-819
-
-
Galassi, A.1
Reynolds, K.2
He, J.3
-
37
-
-
41649119247
-
Protein networks in disease
-
Ideker T, Sharan R: Protein networks in disease. Genome Res. 2008, 18 (4): 644-652. 10.1101/gr.071852.107.
-
(2008)
Genome Res
, vol.18
, Issue.4
, pp. 644-652
-
-
Ideker, T.1
Sharan, R.2
-
38
-
-
13444266370
-
Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders.
-
33 Database
-
Hamosh A, Scott AF, Amberger JS, Bocchini CA, McKusick VA: Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic acids research. 2005, D514-517. 33 Database
-
(2005)
Nucleic acids research.
, pp. D514-D517
-
-
Hamosh, A.1
Scott, A.F.2
Amberger, J.S.3
Bocchini, C.A.4
McKusick, V.A.5
-
39
-
-
2442604715
-
The genetic association database
-
Becker KG, Barnes KC, Bright TJ, Wang SA: The genetic association database. Nature genetics. 2004, 36 (5): 431-432. 10.1038/ng0504-431.
-
(2004)
Nature genetics
, vol.36
, Issue.5
, pp. 431-432
-
-
Becker, K.G.1
Barnes, K.C.2
Bright, T.J.3
Wang, S.A.4
-
40
-
-
57549098807
-
The Catalogue of Somatic Mutations in Cancer (COSMIC).
-
Edited by: Jonathan L Haines [et al]. 2008, Chapter 10: Unit 10 11-
-
Forbes SA, Bhamra G, Bamford S, Dawson E, Kok C, Clements J, Menzies A, Teague JW, Futreal PA, Stratton MR: The Catalogue of Somatic Mutations in Cancer (COSMIC). Current protocols in human genetics/editorial board. Edited by: Jonathan L Haines [et al]. 2008, Chapter 10: Unit 10 11-
-
Current protocols in human genetics/editorial board.
-
-
Forbes, S.A.1
Bhamra, G.2
Bamford, S.3
Dawson, E.4
Kok, C.5
Clements, J.6
Menzies, A.7
Teague, J.W.8
Futreal, P.A.9
Stratton, M.R.10
-
41
-
-
46249104490
-
Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database
-
Allen NC, Bagade S, McQueen MB, Ioannidis JP, Kavvoura FK, Khoury MJ, Tanzi RE, Bertram L: Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nature genetics. 2008, 40 (7): 827-834. 10.1038/ng.171.
-
(2008)
Nature genetics
, vol.40
, Issue.7
, pp. 827-834
-
-
Allen, N.C.1
Bagade, S.2
McQueen, M.B.3
Ioannidis, J.P.4
Kavvoura, F.K.5
Khoury, M.J.6
Tanzi, R.E.7
Bertram, L.8
-
42
-
-
84892833777
-
Discovery and saturation analysis of cancer genes across 21 tumour types
-
Lawrence MS, Stojanov P, Mermel CH, Robinson JT, Garraway LA, Golub TR, Meyerson M, Gabriel SB, Lander ES, Getz G: Discovery and saturation analysis of cancer genes across 21 tumour types. Nature. 2014, 505 (7484): 495-501. 10.1038/nature12912.
-
(2014)
Nature
, vol.505
, Issue.7484
, pp. 495-501
-
-
Lawrence, M.S.1
Stojanov, P.2
Mermel, C.H.3
Robinson, J.T.4
Garraway, L.A.5
Golub, T.R.6
Meyerson, M.7
Gabriel, S.B.8
Lander, E.S.9
Getz, G.10
-
43
-
-
35148838537
-
Drug-target network
-
Yildirim MA, Goh KI, Cusick ME, Barabasi AL, Vidal M: Drug-target network. Nature biotechnology. 2007, 25 (10): 1119-1126. 10.1038/nbt1338.
-
(2007)
Nature biotechnology
, vol.25
, Issue.10
, pp. 1119-1126
-
-
Yildirim, M.A.1
Goh, K.I.2
Cusick, M.E.3
Barabasi, A.L.4
Vidal, M.5
|