메뉴 건너뛰기




Volumn 16, Issue 5, 2015, Pages

A comparative study of disease genes and drug targets in the human protein interactome

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEX NETWORKS; DRUG INTERACTIONS; GENE THERAPY; GENES; PROTEINS;

EID: 84961551930     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-16-S5-S1     Document Type: Article
Times cited : (29)

References (43)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D, Weinberg RA: Hallmarks of cancer: the next generation. Cell. 2011, 144 (5): 646-674. 10.1016/j.cell.2011.02.013.
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 4
    • 0346274979 scopus 로고    scopus 로고
    • New methods for finding disease-susceptibility genes: impact and potential
    • McCarthy MI, Smedley D, Hide W: New methods for finding disease-susceptibility genes: impact and potential. Genome biology. 2003, 4 (10): 119. 10.1186/gb-2003-4-10-119.
    • (2003) Genome biology , vol.4 , Issue.10 , pp. 119.
    • McCarthy, M.I.1    Smedley, D.2    Hide, W.3
  • 5
    • 0037146578 scopus 로고    scopus 로고
    • Finding genes that underlie complex traits
    • Glazier AM, Nadeau JH, Aitman TJ: Finding genes that underlie complex traits. Science. 2002, 298 (5602): 2345-2349. 10.1126/science.1076641.
    • (2002) Science , vol.298 , Issue.5602 , pp. 2345-2349
    • Glazier, A.M.1    Nadeau, J.H.2    Aitman, T.J.3
  • 6
    • 33748092354 scopus 로고    scopus 로고
    • Prevalence and predictors of BRCA1 and BRCA2 mutations in a population-based study of breast cancer in white and black American women ages 35 to 64 years
    • Malone KE, Daling JR, Doody DR, Hsu L, Bernstein L, Coates RJ, Marchbanks PA, Simon MS, McDonald JA, Norman SA, et al: Prevalence and predictors of BRCA1 and BRCA2 mutations in a population-based study of breast cancer in white and black American women ages 35 to 64 years. Cancer research. 2006, 66 (16): 8297-8308. 10.1158/0008-5472.CAN-06-0503.
    • (2006) Cancer research , vol.66 , Issue.16 , pp. 8297-8308
    • Malone, K.E.1    Daling, J.R.2    Doody, D.R.3    Hsu, L.4    Bernstein, L.5    Coates, R.J.6    Marchbanks, P.A.7    Simon, M.S.8    McDonald, J.A.9    Norman, S.A.10
  • 9
    • 75749097005 scopus 로고    scopus 로고
    • Trastuzumab: A review of its use as adjuvant treatment in human epidermal growth factor receptor 2 (HER2)-positive early breast cancer
    • Garnock-Jones KP, Keating GM, Scott LJ: Trastuzumab: A review of its use as adjuvant treatment in human epidermal growth factor receptor 2 (HER2)-positive early breast cancer. Drugs. 2010, 70 (2): 215-239. 10.2165/11203700-000000000-00000.
    • (2010) Drugs , vol.70 , Issue.2 , pp. 215-239
    • Garnock-Jones, K.P.1    Keating, G.M.2    Scott, L.J.3
  • 14
    • 84880557325 scopus 로고    scopus 로고
    • Genomic medicine: a decade of successes, challenges, and opportunities
    • McCarthy JJ, McLeod HL, Ginsburg GS: Genomic medicine: a decade of successes, challenges, and opportunities. Science translational medicine. 2013, 5 (189): 189sr184
    • (2013) Science translational medicine , vol.5 , Issue.189 , pp. 189sr184
    • McCarthy, J.J.1    McLeod, H.L.2    Ginsburg, G.S.3
  • 15
    • 13144306071 scopus 로고    scopus 로고
    • Genome-wide association studies for common diseases and complex traits
    • Hirschhorn JN, Daly MJ: Genome-wide association studies for common diseases and complex traits. Nature reviews Genetics. 2005, 6 (2): 95-108. 10.1038/nrg1521.
    • (2005) Nature reviews Genetics , vol.6 , Issue.2 , pp. 95-108
    • Hirschhorn, J.N.1    Daly, M.J.2
  • 20
    • 78650373804 scopus 로고    scopus 로고
    • Network medicine: a network-based approach to human disease
    • Barabasi AL, Gulbahce N, Loscalzo J: Network medicine: a network-based approach to human disease. Nature reviews Genetics. 2011, 12 (1): 56-68. 10.1038/nrg2918.
    • (2011) Nature reviews Genetics , vol.12 , Issue.1 , pp. 56-68
    • Barabasi, A.L.1    Gulbahce, N.2    Loscalzo, J.3
  • 21
    • 54249155522 scopus 로고    scopus 로고
    • Network pharmacology: the next paradigm in drug discovery
    • Hopkins AL: Network pharmacology: the next paradigm in drug discovery. Nature chemical biology. 2008, 4 (11): 682-690. 10.1038/nchembio.118.
    • (2008) Nature chemical biology , vol.4 , Issue.11 , pp. 682-690
    • Hopkins, A.L.1
  • 22
    • 84878889476 scopus 로고    scopus 로고
    • A vertex similarity-based framework to discover and rank orphan disease-related genes
    • Zhu C, Kushwaha A, Berman K, Jegga AG: A vertex similarity-based framework to discover and rank orphan disease-related genes. BMC systems biology. 2012, 6 (Suppl 3): S8. 10.1186/1752-0509-6-S3-S8.
    • (2012) BMC systems biology , vol.6 , pp. S8.
    • Zhu, C.1    Kushwaha, A.2    Berman, K.3    Jegga, A.G.4
  • 23
    • 84922005241 scopus 로고    scopus 로고
    • Prioritization of orphan disease-causing genes using topological feature and GO similarity between proteins in interaction networks
    • Li M, Li Q, Ganegoda GU, Wang J, Wu F, Pan Y: Prioritization of orphan disease-causing genes using topological feature and GO similarity between proteins in interaction networks. Science China Life sciences. 2014, 57 (11): 1064-1071. 10.1007/s11427-014-4747-6.
    • (2014) Science China Life sciences , vol.57 , Issue.11 , pp. 1064-1071
    • Li, M.1    Li, Q.2    Ganegoda, G.U.3    Wang, J.4    Wu, F.5    Pan, Y.6
  • 24
    • 0742305866 scopus 로고    scopus 로고
    • Network biology: understanding the cell's functional organization
    • Barabasi AL, Oltvai ZN: Network biology: understanding the cell's functional organization. Nature reviews Genetics. 2004, 5 (2): 101-113. 10.1038/nrg1272.
    • (2004) Nature reviews Genetics , vol.5 , Issue.2 , pp. 101-113
    • Barabasi, A.L.1    Oltvai, Z.N.2
  • 25
    • 78649682830 scopus 로고    scopus 로고
    • A comparative study of cancer proteins in the human protein-protein interaction network
    • Sun J, Zhao Z: A comparative study of cancer proteins in the human protein-protein interaction network. BMC Genomics. 2010, 11 (Suppl 3): S5. 10.1186/1471-2164-11-S3-S5.
    • (2010) BMC Genomics , vol.11 , pp. S5
    • Sun, J.1    Zhao, Z.2
  • 26
    • 84255194444 scopus 로고    scopus 로고
    • Integration of breast cancer gene signatures based on graph centrality
    • Wang J, Chen G, Li M, Pan Y: Integration of breast cancer gene signatures based on graph centrality. BMC systems biology. 2011, 5 (Suppl 3): S10. 10.1186/1752-0509-5-S3-S10.
    • (2011) BMC systems biology , vol.5 , pp. S10
    • Wang, J.1    Chen, G.2    Li, M.3    Pan, Y.4
  • 30
    • 23144464901 scopus 로고    scopus 로고
    • WebGestalt: an integrated system for exploring gene sets in various biological contexts.
    • 33 Web Server
    • Zhang B, Kirov S, Snoddy J: WebGestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic acids research. 2005, W741-748. 33 Web Server
    • (2005) Nucleic acids research. , pp. W741-748
    • Zhang, B.1    Kirov, S.2    Snoddy, J.3
  • 32
    • 0034721164 scopus 로고    scopus 로고
    • Error and attack tolerance of complex networks
    • Albert R, Jeong H, Barabasi AL: Error and attack tolerance of complex networks. Nature. 2000, 406 (6794): 378-382. 10.1038/35019019.
    • (2000) Nature , vol.406 , Issue.6794 , pp. 378-382
    • Albert, R.1    Jeong, H.2    Barabasi, A.L.3
  • 34
    • 79151475165 scopus 로고    scopus 로고
    • Immunometabolism: an emerging frontier
    • Mathis D, Shoelson SE: Immunometabolism: an emerging frontier. Nature reviews Immunology. 2011, 11 (2): 81. 10.1038/nri2922.
    • (2011) Nature reviews Immunology , vol.11 , Issue.2 , pp. 81.
    • Mathis, D.1    Shoelson, S.E.2
  • 35
    • 77951069805 scopus 로고    scopus 로고
    • Sympathetic nervous system overactivity and its role in the development of cardiovascular disease
    • Malpas SC: Sympathetic nervous system overactivity and its role in the development of cardiovascular disease. Physiological reviews. 2010, 90 (2): 513-557. 10.1152/physrev.00007.2009.
    • (2010) Physiological reviews , vol.90 , Issue.2 , pp. 513-557
    • Malpas, S.C.1
  • 36
    • 33748776056 scopus 로고    scopus 로고
    • Metabolic syndrome and risk of cardiovascular disease: a meta-analysis
    • Galassi A, Reynolds K, He J: Metabolic syndrome and risk of cardiovascular disease: a meta-analysis. The American journal of medicine. 2006, 119 (10): 812-819. 10.1016/j.amjmed.2006.02.031.
    • (2006) The American journal of medicine , vol.119 , Issue.10 , pp. 812-819
    • Galassi, A.1    Reynolds, K.2    He, J.3
  • 37
    • 41649119247 scopus 로고    scopus 로고
    • Protein networks in disease
    • Ideker T, Sharan R: Protein networks in disease. Genome Res. 2008, 18 (4): 644-652. 10.1101/gr.071852.107.
    • (2008) Genome Res , vol.18 , Issue.4 , pp. 644-652
    • Ideker, T.1    Sharan, R.2
  • 38
    • 13444266370 scopus 로고    scopus 로고
    • Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders.
    • 33 Database
    • Hamosh A, Scott AF, Amberger JS, Bocchini CA, McKusick VA: Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic acids research. 2005, D514-517. 33 Database
    • (2005) Nucleic acids research. , pp. D514-D517
    • Hamosh, A.1    Scott, A.F.2    Amberger, J.S.3    Bocchini, C.A.4    McKusick, V.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.