-
1
-
-
0024523622
-
Tyrosine kinase receptor indistinguishable from the c-met protein
-
Giordano S, Ponzetto C, Di Renzo MF, Cooper CS, Comoglio PM. Tyrosine kinase receptor indistinguishable from the c-met protein. Nature 1989; 339: 155-156.
-
(1989)
Nature
, vol.339
, pp. 155-156
-
-
Giordano, S.1
Ponzetto, C.2
Di Renzo, M.F.3
Cooper, C.S.4
Comoglio, P.M.5
-
2
-
-
0027337146
-
Proteolytic processing of the hepatocyte growth factor/scatter factor receptor by furin
-
Komada M, Hatsuzawa K, Shibamoto S, Ito F, Nakayama K, Kitamura N. Proteolytic processing of the hepatocyte growth factor/scatter factor receptor by furin. FEBS Lett 1993; 328: 25-29.
-
(1993)
FEBS Lett
, vol.328
, pp. 25-29
-
-
Komada, M.1
Hatsuzawa, K.2
Shibamoto, S.3
Ito, F.4
Nakayama, K.5
Kitamura, N.6
-
3
-
-
0025805633
-
Identification of the hepatocyte growth factor receptor as the c-met protooncogene product
-
Bottaro DP, Rubin JS, Faletto DL, Chan AM, Kmiecik TE, Vande Woude GF et al. Identification of the hepatocyte growth factor receptor as the c-met protooncogene product. Science 1991; 251: 802-804.
-
(1991)
Science
, vol.251
, pp. 802-804
-
-
Bottaro, D.P.1
Rubin, J.S.2
Faletto, D.L.3
Chan, A.M.4
Kmiecik, T.E.5
Vande Woude, G.F.6
-
4
-
-
78649420006
-
MET signalling: Principles and functions in development, organ regeneration and cancer
-
Trusolino L, Bertotti A, Comoglio PM. MET signalling: principles and functions in development, organ regeneration and cancer. Nat Rev Mol Cell Biol 2010; 11: 834-848.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 834-848
-
-
Trusolino, L.1
Bertotti, A.2
Comoglio, P.M.3
-
5
-
-
0028346380
-
Interaction of hepatocyte growth factor with heparan sulfate. Elucidation of the major heparan sulfate structural determinants
-
Lyon M, Deakin JA, Mizuno K, Nakamura T, Gallagher JT. Interaction of hepatocyte growth factor with heparan sulfate. Elucidation of the major heparan sulfate structural determinants. J Biol Chem 1994; 269: 11216-11223.
-
(1994)
J Biol Chem
, vol.269
, pp. 11216-11223
-
-
Lyon, M.1
Deakin, J.A.2
Mizuno, K.3
Nakamura, T.4
Gallagher, J.T.5
-
6
-
-
0027761342
-
Activation of hepatocyte growth factor by the plasminogen activators uPA and tPA
-
Mars WM, Zarnegar R, Michalopoulos GK. Activation of hepatocyte growth factor by the plasminogen activators uPA and tPA. Am J Pathol 1993; 143: 949-958.
-
(1993)
Am J Pathol
, vol.143
, pp. 949-958
-
-
Mars, W.M.1
Zarnegar, R.2
Michalopoulos, G.K.3
-
7
-
-
0029985372
-
Emerging multipotent aspects of hepatocyte growth factor
-
Matsumoto K, Nakamura T. Emerging multipotent aspects of hepatocyte growth factor. J Biochem 1996; 119: 591-600.
-
(1996)
J Biochem
, vol.119
, pp. 591-600
-
-
Matsumoto, K.1
Nakamura, T.2
-
8
-
-
0035863786
-
Hepatocyte growth factor is a regulator of monocyte-macrophage function
-
Galimi F, Cottone E, Vigna E, Arena N, Boccaccio C, Giordano S et al. Hepatocyte growth factor is a regulator of monocyte-macrophage function. J Immunol 2001; 166: 1241-1247.
-
(2001)
J Immunol
, vol.166
, pp. 1241-1247
-
-
Galimi, F.1
Cottone, E.2
Vigna, E.3
Arena, N.4
Boccaccio, C.5
Giordano, S.6
-
9
-
-
0036318943
-
The impact of c-met/scatter factor receptor on dendritic cell migration
-
Kurz SM, Diebold SS, Hieronymus T, Gust TC, Bartunek P, Sachs M et al. The impact of c-met/scatter factor receptor on dendritic cell migration. Eur J Immunol 2002; 32: 1832-1838.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1832-1838
-
-
Kurz, S.M.1
Diebold, S.S.2
Hieronymus, T.3
Gust, T.C.4
Bartunek, P.5
Sachs, M.6
-
10
-
-
0033916844
-
Role of hepatocyte growth factor in the development of dendritic cells from CD34+ bone marrow cells
-
Ovali E, Ratip S, Kibaroglu A, Tekelioglu Y, Cetiner M, Karti S et al. Role of hepatocyte growth factor in the development of dendritic cells from CD34+ bone marrow cells. Haematologica 2000; 85: 464-469.
-
(2000)
Haematologica
, vol.85
, pp. 464-469
-
-
Ovali, E.1
Ratip, S.2
Kibaroglu, A.3
Tekelioglu, Y.4
Cetiner, M.5
Karti, S.6
-
11
-
-
0030956759
-
Paracrine regulation of germinal center B cell adhesion through the c-met-hepatocyte growth factor/scatter factor pathway
-
van der Voort R, Taher TE, Keehnen RM, Smit L, Groenink M, Pals ST. Paracrine regulation of germinal center B cell adhesion through the c-met-hepatocyte growth factor/scatter factor pathway. J Exp Med 1997; 185: 2121-2131.
-
(1997)
J Exp Med
, vol.185
, pp. 2121-2131
-
-
Van Der Voort, R.1
Taher, T.E.2
Keehnen, R.M.3
Smit, L.4
Groenink, M.5
Pals, S.T.6
-
12
-
-
0028899952
-
Scatter factor/hepatocyte growth factor is essential for liver development
-
Schmidt C, Bladt F, Goedecke S, Brinkmann V, Zschiesche W, Sharpe M et al. Scatter factor/hepatocyte growth factor is essential for liver development. Nature 1995; 373: 699-702.
-
(1995)
Nature
, vol.373
, pp. 699-702
-
-
Schmidt, C.1
Bladt, F.2
Goedecke, S.3
Brinkmann, V.4
Zschiesche, W.5
Sharpe, M.6
-
13
-
-
0028911690
-
Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor
-
Uehara Y, Minowa O, Mori C, Shiota K, Kuno J, Noda T et al. Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor. Nature 1995; 373: 702-705.
-
(1995)
Nature
, vol.373
, pp. 702-705
-
-
Uehara, Y.1
Minowa, O.2
Mori, C.3
Shiota, K.4
Kuno, J.5
Noda, T.6
-
14
-
-
84888145208
-
C-Met-dependent multipotent labyrinth trophoblast progenitors establish placental exchange interface
-
Ueno M, Lee LK, Chhabra A, Kim YJ, Sasidharan R, Van Handel B et al. c-Met-dependent multipotent labyrinth trophoblast progenitors establish placental exchange interface. Dev Cell 2013; 27: 373-386.
-
(2013)
Dev Cell
, vol.27
, pp. 373-386
-
-
Ueno, M.1
Lee, L.K.2
Chhabra, A.3
Kim, Y.J.4
Sasidharan, R.5
Van Handel, B.6
-
15
-
-
0032189977
-
Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase
-
Birchmeier C, Gherardi E. Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase. Trends Cell Biol 1998; 8: 404-410.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 404-410
-
-
Birchmeier, C.1
Gherardi, E.2
-
16
-
-
0029134104
-
Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud
-
Bladt F, Riethmacher D, Isenmann S, Aguzzi A, Birchmeier C. Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud. Nature 1995; 376: 768-771.
-
(1995)
Nature
, vol.376
, pp. 768-771
-
-
Bladt, F.1
Riethmacher, D.2
Isenmann, S.3
Aguzzi, A.4
Birchmeier, C.5
-
17
-
-
0031440947
-
Met receptor signaling is required for sensory nerve development and HGF promotes axonal growth and survival of sensory neurons
-
Maina F, Hilton MC, Ponzetto C, Davies AM, Klein R. Met receptor signaling is required for sensory nerve development and HGF promotes axonal growth and survival of sensory neurons. Genes Dev 1997; 11: 3341-3350.
-
(1997)
Genes Dev
, vol.11
, pp. 3341-3350
-
-
Maina, F.1
Hilton, M.C.2
Ponzetto, C.3
Davies, A.M.4
Klein, R.5
-
18
-
-
84952001288
-
Cellular and molecular mechanisms of HGF/Met in the cardiovascular system
-
Gallo S, Sala V, Gatti S, Crepaldi T. Cellular and molecular mechanisms of HGF/Met in the cardiovascular system. Clin Sci (Lond) 2015; 129: 1173-1193.
-
(2015)
Clin Sci (Lond)
, vol.129
, pp. 1173-1193
-
-
Gallo, S.1
Sala, V.2
Gatti, S.3
Crepaldi, T.4
-
19
-
-
1842428601
-
Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair
-
Huh CG, Factor VM, Sanchez A, Uchida K, Conner EA, Thorgeirsson SS. Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair. Proc Natl Acad Sci USA 2004; 101: 4477-4482.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4477-4482
-
-
Huh, C.G.1
Factor, V.M.2
Sanchez, A.3
Uchida, K.4
Conner, E.A.5
Thorgeirsson, S.S.6
-
20
-
-
0035023230
-
Hepatocyte growth factor: Renotropic role and potential therapeutics for renal diseases
-
Matsumoto K, Nakamura T. Hepatocyte growth factor: renotropic role and potential therapeutics for renal diseases. Kidney Int 2001; 59: 2023-2038.
-
(2001)
Kidney Int
, vol.59
, pp. 2023-2038
-
-
Matsumoto, K.1
Nakamura, T.2
-
21
-
-
0024427178
-
Molecular cloning and expression of human hepatocyte growth factor
-
Nakamura T, Nishizawa T, Hagiya M, Seki T, Shimonishi M, Sugimura A et al. Molecular cloning and expression of human hepatocyte growth factor. Nature 1989; 342: 440-443.
-
(1989)
Nature
, vol.342
, pp. 440-443
-
-
Nakamura, T.1
Nishizawa, T.2
Hagiya, M.3
Seki, T.4
Shimonishi, M.5
Sugimura, A.6
-
22
-
-
0034995177
-
A potential cardioprotective role of hepatocyte growth factor in myocardial infarction in rats
-
Ueda H, Nakamura T, Matsumoto K, Sawa Y, Matsuda H. A potential cardioprotective role of hepatocyte growth factor in myocardial infarction in rats. Cardiovasc Res 2001; 51: 41-50.
-
(2001)
Cardiovasc Res
, vol.51
, pp. 41-50
-
-
Ueda, H.1
Nakamura, T.2
Matsumoto, K.3
Sawa, Y.4
Matsuda, H.5
-
23
-
-
2942635909
-
Hepatocyte growth factor in kidney fibrosis: Therapeutic potential and mechanisms of action
-
Liu Y. Hepatocyte growth factor in kidney fibrosis: therapeutic potential and mechanisms of action. Am J Physiol Renal Physiol 2004; 287: F7-16.
-
(2004)
Am J Physiol Renal Physiol
, vol.287
, pp. F7-16
-
-
Liu, Y.1
-
24
-
-
0028286615
-
Blood hepatocyte growth factor levels in chronic renal failure patients
-
Chang H, Nagao T, Ichikawa N, Kawamoto T, Nakamura T, Kurokawa K et al. Blood hepatocyte growth factor levels in chronic renal failure patients. Nephron 1994; 67: 497-498.
-
(1994)
Nephron
, vol.67
, pp. 497-498
-
-
Chang, H.1
Nagao, T.2
Ichikawa, N.3
Kawamoto, T.4
Nakamura, T.5
Kurokawa, K.6
-
25
-
-
0028795170
-
Serum hepatocyte growth factor levels in liver diseases: Clinical implications
-
Shiota G, Okano J, Kawasaki H, Kawamoto T, Nakamura T. Serum hepatocyte growth factor levels in liver diseases: clinical implications. Hepatology 1995; 21: 106-112.
-
(1995)
Hepatology
, vol.21
, pp. 106-112
-
-
Shiota, G.1
Okano, J.2
Kawasaki, H.3
Kawamoto, T.4
Nakamura, T.5
-
26
-
-
0030020646
-
Serum HGF levels in acute renal rejection after living related renal transplantation
-
Takada S, Namiki M, Takahara S, Matsumiya K, Kondoh N, Kokado Y et al. Serum HGF levels in acute renal rejection after living related renal transplantation. Transpl Int 1996; 9: 151-154.
-
(1996)
Transpl Int
, vol.9
, pp. 151-154
-
-
Takada, S.1
Namiki, M.2
Takahara, S.3
Matsumiya, K.4
Kondoh, N.5
Kokado, Y.6
-
27
-
-
0026712354
-
Serum hepatocyte growth factor levels in hepatectomized and nonhepatectomized surgical patients
-
Tomiya T, Tani M, Yamada S, Hayashi S, Umeda N, Fujiwara K. Serum hepatocyte growth factor levels in hepatectomized and nonhepatectomized surgical patients. Gastroenterology 1992; 103: 1621-1624.
-
(1992)
Gastroenterology
, vol.103
, pp. 1621-1624
-
-
Tomiya, T.1
Tani, M.2
Yamada, S.3
Hayashi, S.4
Umeda, N.5
Fujiwara, K.6
-
28
-
-
34247142787
-
C-Met is essential for wound healing in the skin
-
Chmielowiec J, Borowiak M, Morkel M, Stradal T, Munz B, Werner S et al. c-Met is essential for wound healing in the skin. J Cell Biol 2007; 177: 151-162.
-
(2007)
J Cell Biol
, vol.177
, pp. 151-162
-
-
Chmielowiec, J.1
Borowiak, M.2
Morkel, M.3
Stradal, T.4
Munz, B.5
Werner, S.6
-
29
-
-
0021241398
-
Molecular cloning of a new transforming gene from a chemically transformed human cell line
-
Cooper CS, Park M, Blair DG, Tainsky MA, Huebner K, Croce CM et al. Molecular cloning of a new transforming gene from a chemically transformed human cell line. Nature 1984; 311: 29-33.
-
(1984)
Nature
, vol.311
, pp. 29-33
-
-
Cooper, C.S.1
Park, M.2
Blair, D.G.3
Tainsky, M.A.4
Huebner, K.5
Croce, C.M.6
-
30
-
-
1242348060
-
Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors
-
Park M, Dean M, Kaul K, Braun MJ, Gonda MA, Vande Woude G. Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors. Proc Natl Acad Sci USA 1987; 84: 6379-6383.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 6379-6383
-
-
Park, M.1
Dean, M.2
Kaul, K.3
Braun, M.J.4
Gonda, M.A.5
Vande Woude, G.6
-
31
-
-
84885234293
-
Cell-autonomous and non-cell-autonomous mechanisms of HGF/MET-driven resistance to targeted therapies: From basic research to a clinical perspective
-
Corso S, Giordano S. Cell-autonomous and non-cell-autonomous mechanisms of HGF/MET-driven resistance to targeted therapies: from basic research to a clinical perspective. Cancer Discov 2013; 3: 978-992.
-
(2013)
Cancer Discov
, vol.3
, pp. 978-992
-
-
Corso, S.1
Giordano, S.2
-
32
-
-
0025828180
-
The TPR-MET oncogenic rearrangement is present and expressed in human gastric carcinoma and precursor lesions
-
Soman NR, Correa P, Ruiz BA, Wogan GN. The TPR-MET oncogenic rearrangement is present and expressed in human gastric carcinoma and precursor lesions. Proc Natl Acad Sci USA 1991; 88: 4892-4896.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 4892-4896
-
-
Soman, N.R.1
Correa, P.2
Ruiz, B.A.3
Wogan, G.N.4
-
33
-
-
84861733799
-
MET: A promising anticancer therapeutic target
-
Peters S, Adjei AA. MET: a promising anticancer therapeutic target. Nat Rev Clin Oncol 2012; 9: 314-326.
-
(2012)
Nat Rev Clin Oncol
, vol.9
, pp. 314-326
-
-
Peters, S.1
Adjei, A.A.2
-
34
-
-
17344381429
-
Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas
-
Schmidt L, Duh FM, Chen F, Kishida T, Glenn G, Choyke P et al. Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas. Nat Genet 1997; 16: 68-73.
-
(1997)
Nat Genet
, vol.16
, pp. 68-73
-
-
Schmidt, L.1
Duh, F.M.2
Chen, F.3
Kishida, T.4
Glenn, G.5
Choyke, P.6
-
35
-
-
0033535530
-
Novel mutations of the MET proto-oncogene in papillary renal carcinomas
-
Schmidt L, Junker K, Nakaigawa N, Kinjerski T, Weirich G, Miller M et al. Novel mutations of the MET proto-oncogene in papillary renal carcinomas. Oncogene 1999; 18: 2343-2350.
-
(1999)
Oncogene
, vol.18
, pp. 2343-2350
-
-
Schmidt, L.1
Junker, K.2
Nakaigawa, N.3
Kinjerski, T.4
Weirich, G.5
Miller, M.6
-
36
-
-
0031006805
-
Activated ras and ret oncogenes induce over-expression of c-met (hepatocyte growth factor receptor) in human thyroid epithelial cells
-
Ivan M, Bond JA, Prat M, Comoglio PM, Wynford-Thomas D. Activated ras and ret oncogenes induce over-expression of c-met (hepatocyte growth factor receptor) in human thyroid epithelial cells. Oncogene 1997; 14: 2417-2423.
-
(1997)
Oncogene
, vol.14
, pp. 2417-2423
-
-
Ivan, M.1
Bond, J.A.2
Prat, M.3
Comoglio, P.M.4
Wynford-Thomas, D.5
-
37
-
-
80052183233
-
Wild-type p53 controls cell motility and invasion by dual regulation of MET expression
-
Hwang CI, Matoso A, Corney DC, Flesken-Nikitin A, Korner S, Wang W et al. Wild-type p53 controls cell motility and invasion by dual regulation of MET expression. Proc Natl Acad Sci USA 2011; 108: 14240-14245.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 14240-14245
-
-
Hwang, C.I.1
Matoso, A.2
Corney, D.C.3
Flesken-Nikitin, A.4
Korner, S.5
Wang, W.6
-
38
-
-
58149352266
-
MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis
-
Stein U, Walther W, Arlt F, Schwabe H, Smith J, Fichtner I et al. MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis. Nat Med 2009; 15: 59-67.
-
(2009)
Nat Med
, vol.15
, pp. 59-67
-
-
Stein, U.1
Walther, W.2
Arlt, F.3
Schwabe, H.4
Smith, J.5
Fichtner, I.6
-
39
-
-
57749089758
-
Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicininduced apoptosis by miR-1
-
Nasser MW, Datta J, Nuovo G, Kutay H, Motiwala T, Majumder S et al. Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicininduced apoptosis by miR-1. J Biol Chem 2008; 283: 33394-33405.
-
(2008)
J Biol Chem
, vol.283
, pp. 33394-33405
-
-
Nasser, M.W.1
Datta, J.2
Nuovo, G.3
Kutay, H.4
Motiwala, T.5
Majumder, S.6
-
40
-
-
84856510440
-
MiR-1 downregulation cooperates with MACC1 in promoting MET overexpression in human colon cancer
-
Migliore C, Martin V, Leoni VP, Restivo A, Atzori L, Petrelli A et al. MiR-1 downregulation cooperates with MACC1 in promoting MET overexpression in human colon cancer. Clin Cancer Res 2012; 18: 737-747.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 737-747
-
-
Migliore, C.1
Martin, V.2
Leoni, V.P.3
Restivo, A.4
Atzori, L.5
Petrelli, A.6
-
41
-
-
0033674048
-
Overexpression and regulation of expression of scatter factor/hepatocyte growth factor in prostatic carcinoma
-
Zhu X, Humphrey PA. Overexpression and regulation of expression of scatter factor/hepatocyte growth factor in prostatic carcinoma. Urology 2000; 56: 1071-1074.
-
(2000)
Urology
, vol.56
, pp. 1071-1074
-
-
Zhu, X.1
Humphrey, P.A.2
-
42
-
-
0031788989
-
Role of hepatocyte growth factor and its receptor c-met in multiple myeloma
-
Seidel C, Borset M, Hjorth-Hansen H, Sundan A, Waage A. Role of hepatocyte growth factor and its receptor c-met in multiple myeloma. Med Oncol 1998; 15: 145-153.
-
(1998)
Med Oncol
, vol.15
, pp. 145-153
-
-
Seidel, C.1
Borset, M.2
Hjorth-Hansen, H.3
Sundan, A.4
Waage, A.5
-
43
-
-
0030690583
-
Met and hepatocyte growth factor/scatter factor expression in human gliomas
-
Koochekpour S, Jeffers M, Rulong S, Taylor G, Klineberg E, Hudson EA et al. Met and hepatocyte growth factor/scatter factor expression in human gliomas. Cancer Res 1997; 57: 5391-5398.
-
(1997)
Cancer Res
, vol.57
, pp. 5391-5398
-
-
Koochekpour, S.1
Jeffers, M.2
Rulong, S.3
Taylor, G.4
Klineberg, E.5
Hudson, E.A.6
-
44
-
-
0029778863
-
Concomitant expression of hepatocyte growth factor/scatter factor and the receptor c-MET in human myeloma cell lines
-
Borset M, Lien E, Espevik T, Helseth E, Waage A, Sundan A. Concomitant expression of hepatocyte growth factor/scatter factor and the receptor c-MET in human myeloma cell lines. J Biol Chem 1996; 271: 24655-24661.
-
(1996)
J Biol Chem
, vol.271
, pp. 24655-24661
-
-
Borset, M.1
Lien, E.2
Espevik, T.3
Helseth, E.4
Waage, A.5
Sundan, A.6
-
45
-
-
84863728707
-
Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia
-
Kentsis A, Reed C, Rice KL, Sanda T, Rodig SJ, Tholouli E et al. Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia. Nat Med 2012; 18: 1118-1122.
-
(2012)
Nat Med
, vol.18
, pp. 1118-1122
-
-
Kentsis, A.1
Reed, C.2
Rice, K.L.3
Sanda, T.4
Rodig, S.J.5
Tholouli, E.6
-
46
-
-
0029444376
-
The Met-HGF/SF autocrine signaling mechanism is involved in sarcomagenesis
-
Cortner J, Vande Woude GF, Rong S. The Met-HGF/SF autocrine signaling mechanism is involved in sarcomagenesis. EXS 1995; 74: 89-121.
-
(1995)
EXS
, vol.74
, pp. 89-121
-
-
Cortner, J.1
Vande Woude, G.F.2
Rong, S.3
-
47
-
-
67650831418
-
Somatic mutation and functional polymorphism of a novel regulatory element in the HGF gene promoter causes its aberrant expression in human breast cancer
-
Ma J, DeFrances MC, Zou C, Johnson C, Ferrell R, Zarnegar R. Somatic mutation and functional polymorphism of a novel regulatory element in the HGF gene promoter causes its aberrant expression in human breast cancer. J Clin Invest 2009; 119: 478-491.
-
(2009)
J Clin Invest
, vol.119
, pp. 478-491
-
-
Ma, J.1
DeFrances, M.C.2
Zou, C.3
Johnson, C.4
Ferrell, R.5
Zarnegar, R.6
-
48
-
-
0030054076
-
Coexpression of hepatocyte growth factor and receptor (Met) in human breast carcinoma
-
Tuck AB, Park M, Sterns EE, Boag A, Elliott BE. Coexpression of hepatocyte growth factor and receptor (Met) in human breast carcinoma. Am J Pathol 1996; 148: 225-232.
-
(1996)
Am J Pathol
, vol.148
, pp. 225-232
-
-
Tuck, A.B.1
Park, M.2
Sterns, E.E.3
Boag, A.4
Elliott, B.E.5
-
49
-
-
0035089315
-
Signaling pathways in the induction of c-met receptor expression by its ligand scatter factor/hepatocyte growth factor in human glioblastoma
-
Abounader R, Ranganathan S, Kim BY, Nichols C, Laterra J. Signaling pathways in the induction of c-met receptor expression by its ligand scatter factor/hepatocyte growth factor in human glioblastoma. J Neurochem 2001; 76: 1497-1508.
-
(2001)
J Neurochem
, vol.76
, pp. 1497-1508
-
-
Abounader, R.1
Ranganathan, S.2
Kim, B.Y.3
Nichols, C.4
Laterra, J.5
-
50
-
-
0242331653
-
Hepatocyte growth factor/scatter factor mediates angiogenesis through positive VEGF and negative thrombospondin 1 regulation
-
Zhang YW, Su Y, Volpert OV, Vande Woude GF. Hepatocyte growth factor/scatter factor mediates angiogenesis through positive VEGF and negative thrombospondin 1 regulation. Proc Natl Acad Sci USA 2003; 100: 12718-12723.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 12718-12723
-
-
Zhang, Y.W.1
Su, Y.2
Volpert, O.V.3
Vande Woude, G.F.4
-
51
-
-
0030325051
-
The integrin alpha 6 beta 4 and the biology of carcinoma
-
Rabinovitz I, Mercurio AM. The integrin alpha 6 beta 4 and the biology of carcinoma. Biochem Cell Biol 1996; 74: 811-821.
-
(1996)
Biochem Cell Biol
, vol.74
, pp. 811-821
-
-
Rabinovitz, I.1
Mercurio, A.M.2
-
52
-
-
0035977147
-
A signaling adapter function for alpha6-beta4 integrin in the control of HGF-dependent invasive growth
-
Trusolino L, Bertotti A, Comoglio PM. A signaling adapter function for alpha6-beta4 integrin in the control of HGF-dependent invasive growth. Cell 2001; 107: 643-654.
-
(2001)
Cell
, vol.107
, pp. 643-654
-
-
Trusolino, L.1
Bertotti, A.2
Comoglio, P.M.3
-
53
-
-
79955063673
-
Hyaluronan-CD44 interactions as potential targets for cancer therapy
-
Misra S, Heldin P, Hascall VC, Karamanos NK, Skandalis SS, Markwald RR et al. Hyaluronan-CD44 interactions as potential targets for cancer therapy. FEBS J 2011; 278: 1429-1443.
-
(2011)
FEBS J
, vol.278
, pp. 1429-1443
-
-
Misra, S.1
Heldin, P.2
Hascall, V.C.3
Karamanos, N.K.4
Skandalis, S.S.5
Markwald, R.R.6
-
54
-
-
0036711644
-
The semaphorin 4D receptor controls invasive growth by coupling with Met
-
Giordano S, Corso S, Conrotto P, Artigiani S, Gilestro G, Barberis D et al. The semaphorin 4D receptor controls invasive growth by coupling with Met. Nat Cell Biol 2002; 4: 720-724.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 720-724
-
-
Giordano, S.1
Corso, S.2
Conrotto, P.3
Artigiani, S.4
Gilestro, G.5
Barberis, D.6
-
55
-
-
71949109556
-
Coexpression of plexin-B1 and Met in human breast and ovary tumours enhances the risk of progression
-
Valente G, Nicotra G, Arrondini M, Castino R, Capparuccia L, Prat M et al. Coexpression of plexin-B1 and Met in human breast and ovary tumours enhances the risk of progression. Cell Oncol 2009; 31: 423-436.
-
(2009)
Cell Oncol
, vol.31
, pp. 423-436
-
-
Valente, G.1
Nicotra, G.2
Arrondini, M.3
Castino, R.4
Capparuccia, L.5
Prat, M.6
-
56
-
-
84859377144
-
MET activation mediates resistance to lapatinib inhibition of HER2-amplified gastric cancer cells
-
Chen CT, Kim H, Liska D, Gao S, Christensen JG, Weiser MR. MET activation mediates resistance to lapatinib inhibition of HER2-amplified gastric cancer cells. Mol Cancer Ther 2012; 11: 660-669.
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 660-669
-
-
Chen, C.T.1
Kim, H.2
Liska, D.3
Gao, S.4
Christensen, J.G.5
Weiser, M.R.6
-
57
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, Park JO et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 2007; 316: 1039-1043.
-
(2007)
Science
, vol.316
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Hyland, C.5
Park, J.O.6
-
58
-
-
84863704553
-
Suppression of tumor invasion and metastasis by concurrent inhibition of c-Met and VEGF signaling in pancreatic neuroendocrine tumors
-
Sennino B, Ishiguro-Oonuma T, Wei Y, Naylor RM, Williamson CW, Bhagwandin V et al. Suppression of tumor invasion and metastasis by concurrent inhibition of c-Met and VEGF signaling in pancreatic neuroendocrine tumors. Cancer Discov 2012; 2: 270-287.
-
(2012)
Cancer Discov
, vol.2
, pp. 270-287
-
-
Sennino, B.1
Ishiguro-Oonuma, T.2
Wei, Y.3
Naylor, R.M.4
Williamson, C.W.5
Bhagwandin, V.6
-
59
-
-
84864285794
-
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
-
Straussman R, Morikawa T, Shee K, Barzily-Rokni M, Qian ZR, Du J et al. Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion. Nature 2012; 487: 500-504.
-
(2012)
Nature
, vol.487
, pp. 500-504
-
-
Straussman, R.1
Morikawa, T.2
Shee, K.3
Barzily-Rokni, M.4
Qian, Z.R.5
Du, J.6
-
60
-
-
56449089812
-
Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations
-
Yano S, Wang W, Li Q, Matsumoto K, Sakurama H, Nakamura T et al. Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations. Cancer Res 2008; 68: 9479-9487.
-
(2008)
Cancer Res
, vol.68
, pp. 9479-9487
-
-
Yano, S.1
Wang, W.2
Li, Q.3
Matsumoto, K.4
Sakurama, H.5
Nakamura, T.6
-
61
-
-
84946590578
-
C-Met is a novel tumor associated antigen for T-cell based immunotherapy against NK/T cell lymphoma
-
Kumai T, Matsuda Y, Ohkuri T, Oikawa K, Ishibashi K, Aoki N et al. c-Met is a novel tumor associated antigen for T-cell based immunotherapy against NK/T cell lymphoma. Oncoimmunology 2015; 4: e976077.
-
(2015)
Oncoimmunology
, vol.4
, pp. e976077
-
-
Kumai, T.1
Matsuda, Y.2
Ohkuri, T.3
Oikawa, K.4
Ishibashi, K.5
Aoki, N.6
-
62
-
-
0026722243
-
Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth
-
Bussolino F, Di Renzo MF, Ziche M, Bocchietto E, Olivero M, Naldini L et al. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol 1992; 119: 629-641.
-
(1992)
J Cell Biol
, vol.119
, pp. 629-641
-
-
Bussolino, F.1
Di Renzo, M.F.2
Ziche, M.3
Bocchietto, E.4
Olivero, M.5
Naldini, L.6
-
63
-
-
3142512610
-
Targeting the tumor and its microenvironment by a dual-function decoy Met receptor
-
Michieli P, Mazzone M, Basilico C, Cavassa S, Sottile A, Naldini L et al. Targeting the tumor and its microenvironment by a dual-function decoy Met receptor. Cancer Cell 2004; 6: 61-73.
-
(2004)
Cancer Cell
, vol.6
, pp. 61-73
-
-
Michieli, P.1
Mazzone, M.2
Basilico, C.3
Cavassa, S.4
Sottile, A.5
Naldini, L.6
-
64
-
-
0028842753
-
In vivo activation of met tyrosine kinase by heterodimeric hepatocyte growth factor molecule promotes angiogenesis
-
Silvagno F, Follenzi A, Arese M, Prat M, Giraudo E, Gaudino G et al. In vivo activation of met tyrosine kinase by heterodimeric hepatocyte growth factor molecule promotes angiogenesis. Arterioscler Thromb Vasc Biol 1995; 15: 1857-1865.
-
(1995)
Arterioscler Thromb Vasc Biol
, vol.15
, pp. 1857-1865
-
-
Silvagno, F.1
Follenzi, A.2
Arese, M.3
Prat, M.4
Giraudo, E.5
Gaudino, G.6
-
65
-
-
84934973340
-
MET is required for the recruitment of anti-tumoural neutrophils
-
Finisguerra V, Di Conza G, Di Matteo M, Serneels J, Costa S, Thompson AA et al. MET is required for the recruitment of anti-tumoural neutrophils. Nature 2015; 522: 349-353.
-
(2015)
Nature
, vol.522
, pp. 349-353
-
-
Finisguerra, V.1
Di Conza, G.2
Di Matteo, M.3
Serneels, J.4
Costa, S.5
Thompson, A.A.6
-
66
-
-
0032900187
-
Hepatocyte growth factor increases expression of vascular endothelial growth factor and plasminogen activator inhibitor-1 in human keratinocytes and the vascular endothelial growth factor receptor flk-1 in human endothelial cells
-
Wojta J, Kaun C, Breuss JM, Koshelnick Y, Beckmann R, Hattey E et al. Hepatocyte growth factor increases expression of vascular endothelial growth factor and plasminogen activator inhibitor-1 in human keratinocytes and the vascular endothelial growth factor receptor flk-1 in human endothelial cells. Lab Invest 1999; 79: 427-438.
-
(1999)
Lab Invest
, vol.79
, pp. 427-438
-
-
Wojta, J.1
Kaun, C.2
Breuss, J.M.3
Koshelnick, Y.4
Beckmann, R.5
Hattey, E.6
-
67
-
-
44449151030
-
Drug development of MET inhibitors: Targeting oncogene addiction and expedience
-
Comoglio PM, Giordano S, Trusolino L. Drug development of MET inhibitors: targeting oncogene addiction and expedience. Nat Rev Drug Discov 2008; 7: 504-516.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 504-516
-
-
Comoglio, P.M.1
Giordano, S.2
Trusolino, L.3
-
68
-
-
20544463213
-
Mechanisms and significance of bifunctional NK4 in cancer treatment
-
Matsumoto K, Nakamura T. Mechanisms and significance of bifunctional NK4 in cancer treatment. Biochem Biophys Res Commun 2005; 333: 316-327.
-
(2005)
Biochem Biophys Res Commun
, vol.333
, pp. 316-327
-
-
Matsumoto, K.1
Nakamura, T.2
-
69
-
-
38449111543
-
NK4 gene therapy targeting HGF-Met and angiogenesis
-
Matsumoto K, Nakamura T. NK4 gene therapy targeting HGF-Met and angiogenesis. Front Biosci 2008; 13: 1943-1951.
-
(2008)
Front Biosci
, vol.13
, pp. 1943-1951
-
-
Matsumoto, K.1
Nakamura, T.2
-
70
-
-
0031065163
-
Angiogenesis induced in vivo by hepatocyte growth factor is mediated by plateletactivating factor synthesis from macrophages
-
Camussi G, Montrucchio G, Lupia E, Soldi R, Comoglio PM, Bussolino F. Angiogenesis induced in vivo by hepatocyte growth factor is mediated by plateletactivating factor synthesis from macrophages. J Immunol 1997; 158: 1302-1309.
-
(1997)
J Immunol
, vol.158
, pp. 1302-1309
-
-
Camussi, G.1
Montrucchio, G.2
Lupia, E.3
Soldi, R.4
Comoglio, P.M.5
Bussolino, F.6
-
71
-
-
33747162725
-
Hepatocyte growth factor mediates angiopoietin-induced smooth muscle cell recruitment
-
Kobayashi H, DeBusk LM, Babichev YO, Dumont DJ, Lin PC. Hepatocyte growth factor mediates angiopoietin-induced smooth muscle cell recruitment. Blood 2006; 108: 1260-1266.
-
(2006)
Blood
, vol.108
, pp. 1260-1266
-
-
Kobayashi, H.1
DeBusk, L.M.2
Babichev, Y.O.3
Dumont, D.J.4
Lin, P.C.5
-
72
-
-
34248529664
-
Hepatocyte growth factor and c-Met expression in pericytes: Implications for atherosclerotic plaque development
-
Liu Y, Wilkinson FL, Kirton JP, Jeziorska M, Iizasa H, Sai Y et al. Hepatocyte growth factor and c-Met expression in pericytes: implications for atherosclerotic plaque development. J Pathol 2007; 212: 12-19.
-
(2007)
J Pathol
, vol.212
, pp. 12-19
-
-
Liu, Y.1
Wilkinson, F.L.2
Kirton, J.P.3
Jeziorska, M.4
Iizasa, H.5
Sai, Y.6
-
73
-
-
84881337812
-
Multipotent human mesenchymal stromal cells mediate expansion of myeloid-derived suppressor cells via hepatocyte growth factor/c-Met and STAT3
-
Yen BL, Yen ML, Hsu PJ, Liu KJ, Wang CJ, Bai CH et al. Multipotent Human Mesenchymal Stromal Cells Mediate Expansion of Myeloid-Derived Suppressor Cells via Hepatocyte Growth Factor/c-Met and STAT3. Stem Cell Reports 2013; 1: 139-151.
-
(2013)
Stem Cell Reports
, vol.1
, pp. 139-151
-
-
Yen, B.L.1
Yen, M.L.2
Hsu, P.J.3
Liu, K.J.4
Wang, C.J.5
Bai, C.H.6
-
74
-
-
78751565017
-
Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling
-
Tesio M, Golan K, Corso S, Giordano S, Schajnovitz A, Vagima Y et al. Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling. Blood 2011; 117: 419-428.
-
(2011)
Blood
, vol.117
, pp. 419-428
-
-
Tesio, M.1
Golan, K.2
Corso, S.3
Giordano, S.4
Schajnovitz, A.5
Vagima, Y.6
-
75
-
-
0027948378
-
Hepatocyte growth factor induces proliferation and differentiation of multipotent and erythroid hemopoietic progenitors
-
Galimi F, Bagnara GP, Bonsi L, Cottone E, Follenzi A, Simeone A et al. Hepatocyte growth factor induces proliferation and differentiation of multipotent and erythroid hemopoietic progenitors. J Cell Biol 1994; 127: 1743-1754.
-
(1994)
J Cell Biol
, vol.127
, pp. 1743-1754
-
-
Galimi, F.1
Bagnara, G.P.2
Bonsi, L.3
Cottone, E.4
Follenzi, A.5
Simeone, A.6
-
76
-
-
0029802366
-
Induction of met proto-oncogene (hepatocyte growth factor receptor) expression during human monocyte-macrophage differentiation
-
Chen Q, DeFrances MC, Zarnegar R. Induction of met proto-oncogene (hepatocyte growth factor receptor) expression during human monocyte-macrophage differentiation. Cell Growth Differ 1996; 7: 821-832.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 821-832
-
-
Chen, Q.1
DeFrances, M.C.2
Zarnegar, R.3
-
77
-
-
20944452151
-
Hepatocyte growth factor ameliorates the progression of experimental autoimmune myocarditis: A potential role for induction of T helper 2 cytokines
-
Futamatsu H, Suzuki J, Mizuno S, Koga N, Adachi S, Kosuge H et al. Hepatocyte growth factor ameliorates the progression of experimental autoimmune myocarditis: a potential role for induction of T helper 2 cytokines. Circ Res 2005; 96: 823-830.
-
(2005)
Circ Res
, vol.96
, pp. 823-830
-
-
Futamatsu, H.1
Suzuki, J.2
Mizuno, S.3
Koga, N.4
Adachi, S.5
Kosuge, H.6
-
78
-
-
0034526510
-
Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF
-
Nakamura T, Mizuno S, Matsumoto K, Sawa Y, Matsuda H, Nakamura T. Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF. J Clin Invest 2000; 106: 1511-1519.
-
(2000)
J Clin Invest
, vol.106
, pp. 1511-1519
-
-
Nakamura, T.1
Mizuno, S.2
Matsumoto, K.3
Sawa, Y.4
Matsuda, H.5
Nakamura, T.6
-
79
-
-
38449089158
-
Hepatocyte growth factor significantly suppresses collagen-induced arthritis in mice
-
Okunishi K, Dohi M, Fujio K, Nakagome K, Tabata Y, Okasora T et al. Hepatocyte growth factor significantly suppresses collagen-induced arthritis in mice. J Immunol 2007; 179: 5504-5513.
-
(2007)
J Immunol
, vol.179
, pp. 5504-5513
-
-
Okunishi, K.1
Dohi, M.2
Fujio, K.3
Nakagome, K.4
Tabata, Y.5
Okasora, T.6
-
80
-
-
0034987974
-
Hepatocyte growth factor ameliorates acute graft-versus-host disease and promotes hematopoietic function
-
Kuroiwa T, Kakishita E, Hamano T, Kataoka Y, Seto Y, Iwata N et al. Hepatocyte growth factor ameliorates acute graft-versus-host disease and promotes hematopoietic function. J Clin Invest 2001; 107: 1365-1373.
-
(2001)
J Clin Invest
, vol.107
, pp. 1365-1373
-
-
Kuroiwa, T.1
Kakishita, E.2
Hamano, T.3
Kataoka, Y.4
Seto, Y.5
Iwata, N.6
-
81
-
-
33748046159
-
Anti-inflammatory effect of hepatocyte growth factor in chronic kidney disease: Targeting the inflamed vascular endothelium
-
Gong R, Rifai A, Dworkin LD. Anti-inflammatory effect of hepatocyte growth factor in chronic kidney disease: targeting the inflamed vascular endothelium. J Am Soc Nephrol 2006; 17: 2464-2473.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2464-2473
-
-
Gong, R.1
Rifai, A.2
Dworkin, L.D.3
-
82
-
-
0032080835
-
Hepatocyte growth factor prevents renal fibrosis and dysfunction in a mouse model of chronic renal disease
-
Mizuno S, Kurosawa T, Matsumoto K, Mizuno-Horikawa Y, Okamoto M, Nakamura T. Hepatocyte growth factor prevents renal fibrosis and dysfunction in a mouse model of chronic renal disease. J Clin Invest 1998; 101: 1827-1834.
-
(1998)
J Clin Invest
, vol.101
, pp. 1827-1834
-
-
Mizuno, S.1
Kurosawa, T.2
Matsumoto, K.3
Mizuno-Horikawa, Y.4
Okamoto, M.5
Nakamura, T.6
-
83
-
-
15244359669
-
Ameliorating effect of hepatocyte growth factor on inflammatory bowel disease in a murine model
-
Oh K, Iimuro Y, Takeuchi M, Kaneda Y, Iwasaki T, Terada N et al. Ameliorating effect of hepatocyte growth factor on inflammatory bowel disease in a murine model. Am J Physiol Gastrointest Liver Physiol 2005; 288: G729-G735.
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.288
, pp. G729-G735
-
-
Oh, K.1
Iimuro, Y.2
Takeuchi, M.3
Kaneda, Y.4
Iwasaki, T.5
Terada, N.6
-
84
-
-
16344367737
-
HGF reduces advancing lung fibrosis in mice: A potential role for MMP-dependent myofibroblast apoptosis
-
Mizuno S, Matsumoto K, Li MY, Nakamura T. HGF reduces advancing lung fibrosis in mice: a potential role for MMP-dependent myofibroblast apoptosis. FASEB J 2005; 19: 580-582.
-
(2005)
FASEB J
, vol.19
, pp. 580-582
-
-
Mizuno, S.1
Matsumoto, K.2
Li, M.Y.3
Nakamura, T.4
-
85
-
-
20844441781
-
Suppression of acute and chronic rejection by hepatocyte growth factor in a murine model of cardiac transplantation: Induction of tolerance and prevention of cardiac allograft vasculopathy
-
Yamaura K, Ito K, Tsukioka K, Wada Y, Makiuchi A, Sakaguchi M et al. Suppression of acute and chronic rejection by hepatocyte growth factor in a murine model of cardiac transplantation: induction of tolerance and prevention of cardiac allograft vasculopathy. Circulation 2004; 110: 1650-1657.
-
(2004)
Circulation
, vol.110
, pp. 1650-1657
-
-
Yamaura, K.1
Ito, K.2
Tsukioka, K.3
Wada, Y.4
Makiuchi, A.5
Sakaguchi, M.6
-
86
-
-
20144388530
-
Hepatocyte growth factor attenuates airway hyperresponsiveness, inflammation, and remodeling
-
Ito W, Kanehiro A, Matsumoto K, Hirano A, Ono K, Maruyama H et al. Hepatocyte growth factor attenuates airway hyperresponsiveness, inflammation, and remodeling. Am J Respir Cell Mol Biol 2005; 32: 268-280.
-
(2005)
Am J Respir Cell Mol Biol
, vol.32
, pp. 268-280
-
-
Ito, W.1
Kanehiro, A.2
Matsumoto, K.3
Hirano, A.4
Ono, K.5
Maruyama, H.6
-
87
-
-
25444439797
-
A novel role of hepatocyte growth factor as an immune regulator through suppressing dendritic cell function
-
Okunishi K, Dohi M, Nakagome K, Tanaka R, Mizuno S, Matsumoto K et al. A novel role of hepatocyte growth factor as an immune regulator through suppressing dendritic cell function. J Immunol 2005; 175: 4745-4753.
-
(2005)
J Immunol
, vol.175
, pp. 4745-4753
-
-
Okunishi, K.1
Dohi, M.2
Nakagome, K.3
Tanaka, R.4
Mizuno, S.5
Matsumoto, K.6
-
88
-
-
84890285948
-
The neurotrophic hepatocyte growth factor attenuates CD8+ cytotoxic T-lymphocyte activity
-
Benkhoucha M, Molnarfi N, Schneiter G, Walker PR, Lalive PH. The neurotrophic hepatocyte growth factor attenuates CD8+ cytotoxic T-lymphocyte activity. J Neuroinflammation 2013; 10: 154.
-
(2013)
J Neuroinflammation
, vol.10
, pp. 154
-
-
Benkhoucha, M.1
Molnarfi, N.2
Schneiter, G.3
Walker, P.R.4
Lalive, P.H.5
-
89
-
-
77950913921
-
Hepatocyte growth factor inhibits CNS autoimmunity by inducing tolerogenic dendritic cells and CD25+Foxp3+ regulatory T cells
-
Benkhoucha M, Santiago-Raber ML, Schneiter G, Chofflon M, Funakoshi H, Nakamura T et al. Hepatocyte growth factor inhibits CNS autoimmunity by inducing tolerogenic dendritic cells and CD25+Foxp3+ regulatory T cells. Proc Natl Acad Sci USA 2010; 107: 6424-6429.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 6424-6429
-
-
Benkhoucha, M.1
Santiago-Raber, M.L.2
Schneiter, G.3
Chofflon, M.4
Funakoshi, H.5
Nakamura, T.6
-
90
-
-
84904993626
-
Induction of immunomodulatory monocytes by human mesenchymal stem cell-derived hepatocyte growth factor through ERK1/2
-
Chen PM, Liu KJ, Hsu PJ, Wei CF, Bai CH, Ho LJ et al. Induction of immunomodulatory monocytes by human mesenchymal stem cell-derived hepatocyte growth factor through ERK1/2. J Leukoc Biol 2014; 96: 295-303.
-
(2014)
J Leukoc Biol
, vol.96
, pp. 295-303
-
-
Chen, P.M.1
Liu, K.J.2
Hsu, P.J.3
Wei, C.F.4
Bai, C.H.5
Ho, L.J.6
-
91
-
-
84896350971
-
Hepatocyte growth factor in dampening liver immune-mediated pathology in acute viral hepatitis without compromising antiviral activity
-
Aguilar-Valenzuela R, Carlsen ED, Liang Y, Soong L, Sun J. Hepatocyte growth factor in dampening liver immune-mediated pathology in acute viral hepatitis without compromising antiviral activity. J Gastroenterol Hepatol 2014; 29: 878-886.
-
(2014)
J Gastroenterol Hepatol
, vol.29
, pp. 878-886
-
-
Aguilar-Valenzuela, R.1
Carlsen, E.D.2
Liang, Y.3
Soong, L.4
Sun, J.5
-
92
-
-
0028365273
-
Hepatocyte growth factor and macrophage inflammatory protein 1 beta: Structurally distinct cytokines that induce rapid cytoskeletal changes and subsetpreferential migration in T cells
-
Adams DH, Harvath L, Bottaro DP, Interrante R, Catalano G, Tanaka Y et al. Hepatocyte growth factor and macrophage inflammatory protein 1 beta: structurally distinct cytokines that induce rapid cytoskeletal changes and subsetpreferential migration in T cells. Proc Natl Acad Sci USA 1994; 91: 7144-7148.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7144-7148
-
-
Adams, D.H.1
Harvath, L.2
Bottaro, D.P.3
Interrante, R.4
Catalano, G.5
Tanaka, Y.6
-
93
-
-
0035047992
-
The role of hepatocyte growth factor and its receptor c-met in interactions between lymphocytes and stromal cells in secondary human lymphoid organs
-
Skibinski G, Skibinska A, James K. The role of hepatocyte growth factor and its receptor c-met in interactions between lymphocytes and stromal cells in secondary human lymphoid organs. Immunology 2001; 102: 506-514.
-
(2001)
Immunology
, vol.102
, pp. 506-514
-
-
Skibinski, G.1
Skibinska, A.2
James, K.3
-
94
-
-
0037093058
-
Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
-
Di Nicola M, Carlo-Stella C, Magni M, Milanesi M, Longoni PD, Matteucci P et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 2002; 99: 3838-3843.
-
(2002)
Blood
, vol.99
, pp. 3838-3843
-
-
Di Nicola, M.1
Carlo-Stella, C.2
Magni, M.3
Milanesi, M.4
Longoni, P.D.5
Matteucci, P.6
-
95
-
-
0031955446
-
Expression and function of c-Met, a receptor for hepatocyte growth factor, during T-cell development
-
Tamura S, Sugawara T, Tokoro Y, Taniguchi H, Fukao K, Nakauchi H et al. Expression and function of c-Met, a receptor for hepatocyte growth factor, during T-cell development. Scand J Immunol 1998; 47: 296-301.
-
(1998)
Scand J Immunol
, vol.47
, pp. 296-301
-
-
Tamura, S.1
Sugawara, T.2
Tokoro, Y.3
Taniguchi, H.4
Fukao, K.5
Nakauchi, H.6
-
96
-
-
84937557229
-
Hepatocyte growth factor receptor c-met instructs t cell cardiotropism and promotes T Cell migration to the heart via autocrine Chemokine release
-
Komarowska I, Coe D, Wang G, Haas R, Mauro C, Kishore M et al. Hepatocyte Growth Factor Receptor c-Met Instructs T Cell Cardiotropism and Promotes T Cell Migration to the Heart via Autocrine Chemokine Release. Immunity 2015; 42: 1087-1099.
-
(2015)
Immunity
, vol.42
, pp. 1087-1099
-
-
Komarowska, I.1
Coe, D.2
Wang, G.3
Haas, R.4
Mauro, C.5
Kishore, M.6
-
97
-
-
0030669279
-
Neoexpression of the c-met/hepatocyte growth factor-scatter factor receptor gene in activated monocytes
-
Beilmann M, Odenthal M, Jung W, Vande Woude GF, Dienes HP, Schirmacher P. Neoexpression of the c-met/hepatocyte growth factor-scatter factor receptor gene in activated monocytes. Blood 1997; 90: 4450-4458.
-
(1997)
Blood
, vol.90
, pp. 4450-4458
-
-
Beilmann, M.1
Odenthal, M.2
Jung, W.3
Vande Woude, G.F.4
Dienes, H.P.5
Schirmacher, P.6
-
98
-
-
77749252671
-
Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis
-
Moransard M, Sawitzky M, Fontana A, Suter T. Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis. Glia 2010; 58: 559-571.
-
(2010)
Glia
, vol.58
, pp. 559-571
-
-
Moransard, M.1
Sawitzky, M.2
Fontana, A.3
Suter, T.4
-
99
-
-
84945465803
-
C-Met identifies a population of matrix metalloproteinase 9-producing monocytes in peritumoural stroma of hepatocellular carcinoma
-
Zhao L, Wu Y, Xie XD, Chu YF, Li JQ, Zheng L. c-Met identifies a population of matrix metalloproteinase 9-producing monocytes in peritumoural stroma of hepatocellular carcinoma. J Pathol 2015; 237: 319-329.
-
(2015)
J Pathol
, vol.237
, pp. 319-329
-
-
Zhao, L.1
Wu, Y.2
Xie, X.D.3
Chu, Y.F.4
Li, J.Q.5
Zheng, L.6
-
101
-
-
84871721240
-
Tivantinib for second-line treatment of advanced hepatocellular carcinoma: A randomised, placebo-controlled phase 2 study
-
Santoro A, Rimassa L, Borbath I, Daniele B, Salvagni S, Van Laethem JL et al. Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-controlled phase 2 study. Lancet Oncol 2013; 14: 55-63.
-
(2013)
Lancet Oncol
, vol.14
, pp. 55-63
-
-
Santoro, A.1
Rimassa, L.2
Borbath, I.3
Daniele, B.4
Salvagni, S.5
Van Laethem, J.L.6
-
102
-
-
78149492010
-
Hepatocyte growth factor modulates interleukin-6 production in bone marrow derived macrophages: Implications for inflammatory mediated diseases
-
Coudriet GM, He J, Trucco M, Mars WM, Piganelli JD. Hepatocyte growth factor modulates interleukin-6 production in bone marrow derived macrophages: implications for inflammatory mediated diseases. PLoS One 2010; 5: e15384.
-
(2010)
PLoS One
, vol.5
, pp. e15384
-
-
Coudriet, G.M.1
He, J.2
Trucco, M.3
Mars, W.M.4
Piganelli, J.D.5
-
103
-
-
84864803976
-
The HGF receptor/Met tyrosine kinase is a key regulator of dendritic cell migration in skin immunity
-
Baek JH, Birchmeier C, Zenke M, Hieronymus T. The HGF receptor/Met tyrosine kinase is a key regulator of dendritic cell migration in skin immunity. J Immunol 2012; 189: 1699-1707.
-
(2012)
J Immunol
, vol.189
, pp. 1699-1707
-
-
Baek, J.H.1
Birchmeier, C.2
Zenke, M.3
Hieronymus, T.4
-
104
-
-
84877665014
-
Imaging haematopoietic cells recruitment to an acute wound in vivo identifies a role for c-Met signalling
-
Falenta K, Rodaway A, Jones GE, Wells CM. Imaging haematopoietic cells recruitment to an acute wound in vivo identifies a role for c-Met signalling. J Microsc 2013; 250: 200-209.
-
(2013)
J Microsc
, vol.250
, pp. 200-209
-
-
Falenta, K.1
Rodaway, A.2
Jones, G.E.3
Wells, C.M.4
-
105
-
-
0026787198
-
Neutrophil priming by hepatocyte growth factor, a novel cytokine
-
Jiang W, Puntis MC, Nakamura T, Hallett MB. Neutrophil priming by hepatocyte growth factor, a novel cytokine. Immunology 1992; 77: 147-149.
-
(1992)
Immunology
, vol.77
, pp. 147-149
-
-
Jiang, W.1
Puntis, M.C.2
Nakamura, T.3
Hallett, M.B.4
-
106
-
-
0031788307
-
Hepatocyte growth factor is a potent trigger of neutrophil adhesion through rapid activation of lymphocyte function-associated antigen-1
-
Mine S, Tanaka Y, Suematu M, Aso M, Fujisaki T, Yamada S et al. Hepatocyte growth factor is a potent trigger of neutrophil adhesion through rapid activation of lymphocyte function-associated antigen-1. Lab Invest 1998; 78: 1395-1404.
-
(1998)
Lab Invest
, vol.78
, pp. 1395-1404
-
-
Mine, S.1
Tanaka, Y.2
Suematu, M.3
Aso, M.4
Fujisaki, T.5
Yamada, S.6
-
107
-
-
80052566377
-
Tumor entrained neutrophils inhibit seeding in the premetastatic lung
-
Granot Z, Henke E, Comen EA, King TA, Norton L, Benezra R. Tumor entrained neutrophils inhibit seeding in the premetastatic lung. Cancer Cell 2011; 20: 300-314.
-
(2011)
Cancer Cell
, vol.20
, pp. 300-314
-
-
Granot, Z.1
Henke, E.2
Comen, E.A.3
King, T.A.4
Norton, L.5
Benezra, R.6
-
108
-
-
84922777488
-
Phenotypic diversity and plasticity in circulating neutrophil subpopulations in cancer
-
Sagiv JY, Michaeli J, Assi S, Mishalian I, Kisos H, Levy L et al. Phenotypic diversity and plasticity in circulating neutrophil subpopulations in cancer. Cell Rep 2015; 10: 562-573.
-
(2015)
Cell Rep
, vol.10
, pp. 562-573
-
-
Sagiv, J.Y.1
Michaeli, J.2
Assi, S.3
Mishalian, I.4
Kisos, H.5
Levy, L.6
-
109
-
-
84926473508
-
IL-17-producing gammadelta T cells and neutrophils conspire to promote breast cancer metastasis
-
Coffelt SB, Kersten K, Doornebal CW, Weiden J, Vrijland K, Hau CS et al. IL-17-producing gammadelta T cells and neutrophils conspire to promote breast cancer metastasis. Nature 2015; 522: 345-348.
-
(2015)
Nature
, vol.522
, pp. 345-348
-
-
Coffelt, S.B.1
Kersten, K.2
Doornebal, C.W.3
Weiden, J.4
Vrijland, K.5
Hau, C.S.6
-
110
-
-
84950299450
-
Neutrophils support lung colonization of metastasisinitiating breast cancer cells
-
Wculek SK, Malanchi I. Neutrophils support lung colonization of metastasisinitiating breast cancer cells. Nature 2015; 528: 413-417.
-
(2015)
Nature
, vol.528
, pp. 413-417
-
-
Wculek, S.K.1
Malanchi, I.2
-
111
-
-
69249222379
-
Polarization of tumor-associated neutrophil phenotype by TGF-beta: N1 versus "n2" TAN
-
Fridlender ZG, Sun J, Kim S, Kapoor V, Cheng G, Ling L et al. Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN. Cancer Cell 2009; 16: 183-194.
-
(2009)
Cancer Cell
, vol.16
, pp. 183-194
-
-
Fridlender, Z.G.1
Sun, J.2
Kim, S.3
Kapoor, V.4
Cheng, G.5
Ling, L.6
-
112
-
-
0034728780
-
Mechanism of regulation of HGF/SF gene expression in fibroblasts by TGF-beta1
-
Harrison P, Bradley L, Bomford A. Mechanism of regulation of HGF/SF gene expression in fibroblasts by TGF-beta1. Biochem Biophys Res Commun 2000; 271: 203-211.
-
(2000)
Biochem Biophys Res Commun
, vol.271
, pp. 203-211
-
-
Harrison, P.1
Bradley, L.2
Bomford, A.3
-
113
-
-
84879618751
-
Transforming growth factor-beta1 selectively inhibits hepatocyte growth factor expression via a micro-RNA-199-dependent posttranscriptional mechanism
-
Mungunsukh O, Day RM. Transforming growth factor-beta1 selectively inhibits hepatocyte growth factor expression via a micro-RNA-199-dependent posttranscriptional mechanism. Mol Biol Cell 2013; 24: 2088-2097.
-
(2013)
Mol Biol Cell
, vol.24
, pp. 2088-2097
-
-
Mungunsukh, O.1
Day, R.M.2
-
114
-
-
0027203305
-
Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta
-
Vodovotz Y, Bogdan C, Paik J, Xie QW, Nathan C. Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta. J Exp Med 1993; 178: 605-613.
-
(1993)
J Exp Med
, vol.178
, pp. 605-613
-
-
Vodovotz, Y.1
Bogdan, C.2
Paik, J.3
Xie, Q.W.4
Nathan, C.5
-
115
-
-
84902313522
-
The potential roles of hepatocyte growth factor (HGF)-MET pathway inhibitors in cancer treatment
-
Parikh RA, Wang P, Beumer JH, Chu E, Appleman LJ. The potential roles of hepatocyte growth factor (HGF)-MET pathway inhibitors in cancer treatment. Onco Targets Ther 2014; 7: 969-983.
-
(2014)
Onco Targets Ther
, vol.7
, pp. 969-983
-
-
Parikh, R.A.1
Wang, P.2
Beumer, J.H.3
Chu, E.4
Appleman, L.J.5
-
116
-
-
38549156012
-
Silencing the MET oncogene leads to regression of experimental tumors and metastases
-
Corso S, Migliore C, Ghiso E, De Rosa G, Comoglio PM, Giordano S. Silencing the MET oncogene leads to regression of experimental tumors and metastases. Oncogene 2008; 27: 684-693.
-
(2008)
Oncogene
, vol.27
, pp. 684-693
-
-
Corso, S.1
Migliore, C.2
Ghiso, E.3
De Rosa, G.4
Comoglio, P.M.5
Giordano, S.6
-
117
-
-
84943745810
-
Tivantinib added to erlotinib in nonsmall-cell lung cancer: The primary end point was not MET
-
Scagliotti GV, Di Maio M. Tivantinib added to erlotinib in nonsmall-cell lung cancer: the primary end point was not MET. Ann Oncol 2015; 26: 2007-2009.
-
(2015)
Ann Oncol
, vol.26
, pp. 2007-2009
-
-
Scagliotti, G.V.1
Di Maio, M.2
-
118
-
-
84905373271
-
MET inhibitors start on road to recovery
-
Garber K. MET inhibitors start on road to recovery. Nat Rev Drug Discov 2014; 13: 563-565.
-
(2014)
Nat Rev Drug Discov
, vol.13
, pp. 563-565
-
-
Garber, K.1
-
119
-
-
84905028489
-
Rilotumumab in combination with epirubicin cisplatin and capecitabine as firstline treatment for gastric or oesophagogastric junction adenocarcinoma: An open-label dose de-escalation phase 1b study and a double-blind randomised phase 2 study
-
Iveson T, Donehower RC, Davidenko I, Tjulandin S, Deptala A, Harrison M et al. Rilotumumab in combination with epirubicin, cisplatin, and capecitabine as firstline treatment for gastric or oesophagogastric junction adenocarcinoma: an open-label, dose de-escalation phase 1b study and a double-blind, randomised phase 2 study. Lancet Oncol 2014; 15: 1007-1018.
-
(2014)
Lancet Oncol
, vol.15
, pp. 1007-1018
-
-
Iveson, T.1
Donehower, R.C.2
Davidenko, I.3
Tjulandin, S.4
Deptala, A.5
Harrison, M.6
-
121
-
-
84555190809
-
MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib
-
Lennerz JK, Kwak EL, Ackerman A, Michael M, Fox SB, Bergethon K et al. MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib. J Clin Oncol 2011; 29: 4803-4810.
-
(2011)
J Clin Oncol
, vol.29
, pp. 4803-4810
-
-
Lennerz, J.K.1
Kwak, E.L.2
Ackerman, A.3
Michael, M.4
Fox, S.B.5
Bergethon, K.6
-
122
-
-
84872548337
-
Phase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma
-
Choueiri TK, Vaishampayan U, Rosenberg JE, Logan TF, Harzstark AL, Bukowski RM et al. Phase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma. J Clin Oncol 2013; 31: 181-186.
-
(2013)
J Clin Oncol
, vol.31
, pp. 181-186
-
-
Choueiri, T.K.1
Vaishampayan, U.2
Rosenberg, J.E.3
Logan, T.F.4
Harzstark, A.L.5
Bukowski, R.M.6
-
123
-
-
84931068909
-
Adoptive therapy with CAR redirected T cells: The challenges in targeting solid tumors
-
Abken H. Adoptive therapy with CAR redirected T cells: the challenges in targeting solid tumors. Immunotherapy 2015; 7: 535-544.
-
(2015)
Immunotherapy
, vol.7
, pp. 535-544
-
-
Abken, H.1
-
124
-
-
84940379637
-
Adoptive cell therapy-tumor-infiltrating lymphocytes, T-cell receptors, and chimeric antigen receptors
-
Feldman SA, Assadipour Y, Kriley I, Goff SL, Rosenberg SA. Adoptive cell therapy-tumor-infiltrating lymphocytes, T-cell receptors, and chimeric antigen receptors. Semin Oncol 2015; 42: 626-639.
-
(2015)
Semin Oncol
, vol.42
, pp. 626-639
-
-
Feldman, S.A.1
Assadipour, Y.2
Kriley, I.3
Goff, S.L.4
Rosenberg, S.A.5
-
125
-
-
84921487573
-
Designing chimeric antigen receptors to effectively and safely target tumors
-
Jensen MC, Riddell SR. Designing chimeric antigen receptors to effectively and safely target tumors. Curr Opin Immunol 2015; 33: 9-15.
-
(2015)
Curr Opin Immunol
, vol.33
, pp. 9-15
-
-
Jensen, M.C.1
Riddell, S.R.2
-
126
-
-
41149097574
-
Adoptive cell transfer: A clinical path to effective cancer immunotherapy
-
Rosenberg SA, Restifo NP, Yang JC, Morgan RA, Dudley ME. Adoptive cell transfer: a clinical path to effective cancer immunotherapy. Nat Rev Cancer 2008; 8: 299-308.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 299-308
-
-
Rosenberg, S.A.1
Restifo, N.P.2
Yang, J.C.3
Morgan, R.A.4
Dudley, M.E.5
-
127
-
-
84890551686
-
A novel bispecific EGFR/Met antibody blocks tumor-promoting phenotypic effects induced by resistance to EGFR inhibition and has potent antitumor activity
-
Castoldi R, Ecker V, Wiehle L, Majety M, Busl-Schuller R, Asmussen M et al. A novel bispecific EGFR/Met antibody blocks tumor-promoting phenotypic effects induced by resistance to EGFR inhibition and has potent antitumor activity. Oncogene 2013; 32: 5593-5601.
-
(2013)
Oncogene
, vol.32
, pp. 5593-5601
-
-
Castoldi, R.1
Ecker, V.2
Wiehle, L.3
Majety, M.4
Busl-Schuller, R.5
Asmussen, M.6
-
129
-
-
84907561441
-
Safety and efficacy of INC280 in combination with gefinitib in patients with EGFR mutated, MET-positive NSCLC: A single arm phase lb/II study
-
Wu YL, Yang JC-H, Kim D-W, Su W-C, Ahn M-J, Lee DH et al. Safety and efficacy of INC280 in combination with gefinitib in patients with EGFR mutated, MET-positive NSCLC: a single arm phase lb/II study. J Clin Oncol 2014; 32.
-
(2014)
J Clin Oncol
, pp. 32
-
-
Wu, Y.L.1
Jc-H, Y.2
Kim, D.-W.3
Su, W.-C.4
Ahn, M.-J.5
Lee, D.H.6
-
130
-
-
84943737027
-
A randomized, double-blind, placebo-controlled, phase III trial of erlotinib with or without a c-Met inhibitor tivantinib (ARQ 197)in Asian patients with previously treated stage IIIB/IV nonsquamous nonsmall-cell lung cancer harboring wildtype epidermal growth factor receptor (ATTENTION study)
-
Yoshioka H, Azuma K, Yamamoto N, Takahashi T, Nishio M, Katakami N et al. A randomized, double-blind, placebo-controlled, phase III trial of erlotinib with or without a c-Met inhibitor tivantinib (ARQ 197) in Asian patients with previously treated stage IIIB/IV nonsquamous nonsmall-cell lung cancer harboring wildtype epidermal growth factor receptor (ATTENTION study). Ann Oncol 2015; 26: 2066-2072.
-
(2015)
Ann Oncol
, vol.26
, pp. 2066-2072
-
-
Yoshioka, H.1
Azuma, K.2
Yamamoto, N.3
Takahashi, T.4
Nishio, M.5
Katakami, N.6
-
131
-
-
84942197665
-
Phase II study of tivantinib (ARQ 197) in patients with metastatic triple-negative breast cancer
-
Tolaney SM, Tan S, Guo H, Barry W, Van Allen E, Wagle N et al. Phase II study of tivantinib (ARQ 197) in patients with metastatic triple-negative breast cancer. Invest New Drugs 2015; 33: 1108-1114.
-
(2015)
Invest New Drugs
, vol.33
, pp. 1108-1114
-
-
Tolaney, S.M.1
Tan, S.2
Guo, H.3
Barry, W.4
Van Allen, E.5
Wagle, N.6
-
132
-
-
33748162638
-
Tolerogenic dendritic cells: Cytokine modulation comes of age
-
Rutella S, Danese S, Leone G. Tolerogenic dendritic cells: cytokine modulation comes of age. Blood 2006; 108: 1435-1440.
-
(2006)
Blood
, vol.108
, pp. 1435-1440
-
-
Rutella, S.1
Danese, S.2
Leone, G.3
-
133
-
-
84055212018
-
A phase i dose-escalation study of Tivantinib (ARQ 197) in adult patients with metastatic solid tumors
-
Rosen LS, Senzer N, Mekhail T, Ganapathi R, Chai F, Savage RE et al. A phase I dose-escalation study of Tivantinib (ARQ 197) in adult patients with metastatic solid tumors. Clin Cancer Res 2011; 17: 7754-7764.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 7754-7764
-
-
Rosen, L.S.1
Senzer, N.2
Mekhail, T.3
Ganapathi, R.4
Chai, F.5
Savage, R.E.6
-
134
-
-
79953885749
-
Phase i trial of a selective c-MET inhibitor ARQ197 incorporating proof of mechanism pharmacodynamics studies
-
Yap TA, Olmos D, Brunetto AT, Tunariu N, Barriuso J, Riisnaes R et al. Phase I trial of a selective c-MET inhibitor ARQ197 incorporating proof of mechanism pharmacodynamics studies. J Clin Oncol 2011; 29: 1271-1279.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1271-1279
-
-
Yap, T.A.1
Olmos, D.2
Brunetto, A.T.3
Tunariu, N.4
Barriuso, J.5
Riisnaes, R.6
-
135
-
-
84869499839
-
Phase 1 doseescalation trial evaluating the combination of the selective MET (mesenchymalepithelial transition factor) inhibitor tivantinib (ARQ 197) plus erlotinib
-
Goldman JW, Laux I, Chai F, Savage RE, Ferrari D, Garmey EG et al. Phase 1 doseescalation trial evaluating the combination of the selective MET (mesenchymalepithelial transition factor) inhibitor tivantinib (ARQ 197) plus erlotinib. Cancer 2012; 118: 5903-5911.
-
(2012)
Cancer
, vol.118
, pp. 5903-5911
-
-
Goldman, J.W.1
Laux, I.2
Chai, F.3
Savage, R.E.4
Ferrari, D.5
Garmey, E.G.6
-
136
-
-
84903735438
-
A phase i dose escalation study of oral c-MET inhibitor tivantinib (ARQ 197) in combination with gemcitabine in patients with solid tumors
-
Pant S, Saleh M, Bendell J, Infante JR, Jones S, Kurkjian CD et al. A phase I dose escalation study of oral c-MET inhibitor tivantinib (ARQ 197) in combination with gemcitabine in patients with solid tumors. Ann Oncol 2014; 25: 1416-1421.
-
(2014)
Ann Oncol
, vol.25
, pp. 1416-1421
-
-
Pant, S.1
Saleh, M.2
Bendell, J.3
Infante, J.R.4
Jones, S.5
Kurkjian, C.D.6
-
137
-
-
85005957850
-
Phase i trial of tivantinib in combination with carboplatin and pemetrexed as first-line treatment in patients with advanced nonsquamous non small cell lung cancer or malignant pleural mesothelioma
-
Zucali PA, Simonelli M, De Vincenzo F, Fatuzzo G, Bertossi M, Perrino M et al. Phase I trial of tivantinib in combination with carboplatin and pemetrexed as first-line treatment in patients with advanced nonsquamous non small cell lung cancer or malignant pleural mesothelioma. J Clin Oncol 2015; 33: 2549.
-
(2015)
J Clin Oncol
, vol.33
, pp. 2549
-
-
Zucali, P.A.1
Simonelli, M.2
De Vincenzo, F.3
Fatuzzo, G.4
Bertossi, M.5
Perrino, M.6
-
138
-
-
80051974548
-
Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer
-
Sequist LV, von Pawel J, Garmey EG, Akerley WL, Brugger W, Ferrari D et al. Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer. J Clin Oncol 2011; 29: 3307-3315.
-
(2011)
J Clin Oncol
, vol.29
, pp. 3307-3315
-
-
Sequist, L.V.1
Von Pawel, J.2
Garmey, E.G.3
Akerley, W.L.4
Brugger, W.5
Ferrari, D.6
-
139
-
-
84880923318
-
A phase 2 multicenter study of tivantinib monotherapy in patients with relapsed or refractory germ cell tumors
-
Feldman DR EL, Quinn DI, Loriot Y, Joffe JK, Vaughn DJ, Fléchon A et al. A phase 2 multicenter study of tivantinib monotherapy in patients with relapsed or refractory germ cell tumors. Invest New Drugs 2013; 31: 1016-1022.
-
(2013)
Invest New Drugs
, vol.31
, pp. 1016-1022
-
-
Feldman, D.R.E.L.1
Quinn, D.I.2
Loriot, Y.3
Joffe, J.K.4
Vaughn, D.J.5
Fléchon, A.6
-
140
-
-
84896404764
-
A phase II trial of a selective c-Met inhibitor tivantinib (ARQ 197) monotherapy as a second-or thirdline therapy in the patients with metastatic gastric cancer
-
Kang YK, Muro K, Ryu MH, Yasui H, Nishina T, Ryoo BY et al. A phase II trial of a selective c-Met inhibitor tivantinib (ARQ 197) monotherapy as a second-or thirdline therapy in the patients with metastatic gastric cancer. Invest New Drugs 2014; 32: 355-361.
-
(2014)
Invest New Drugs
, vol.32
, pp. 355-361
-
-
Kang, Y.K.1
Muro, K.2
Ryu, M.H.3
Yasui, H.4
Nishina, T.5
Ryoo, B.Y.6
-
141
-
-
85017343055
-
A phase II study of the c-Met inhibitor tivantinib in combination with FOLFOX for the treatment of patients with previously untreated metastatic adenocarcinoma of the distal esophagus, gastroesophageal (GE) junction, or stomach
-
Pant S, Patel MR, Kurkijan C, Hemphill MB, Flores MRC. A phase II study of the c-Met inhibitor tivantinib in combination with FOLFOX for the treatment of patients with previously untreated metastatic adenocarcinoma of the distal esophagus, gastroesophageal (GE) junction, or stomach. J Clin Oncol 2015; 33: 4065.
-
(2015)
J Clin Oncol
, vol.33
, pp. 4065
-
-
Pant, S.1
Patel, M.R.2
Kurkijan, C.3
Hemphill, M.B.4
Flores, M.R.C.5
-
142
-
-
84978158619
-
SWOG 1107: Parallel (randomized) phase II evaluation of tivantinib (ARQ197) and tivantinib in combination with erlotinib in patients with papillary renal cell carcinoma (pRCC)
-
Twardowski P, Plets M, Plimack ER, Agarwal N, Tangen CM, Vogelzang NJ et al. SWOG 1107: parallel (randomized) phase II evaluation of tivantinib (ARQ197) and tivantinib in combination with erlotinib in patients with papillary renal cell carcinoma (pRCC). J Clin Oncol 2015; 33: 4523.
-
(2015)
J Clin Oncol
, vol.33
, pp. 4523
-
-
Twardowski, P.1
Plets, M.2
Plimack, E.R.3
Agarwal, N.4
Tangen, C.M.5
Vogelzang, N.J.6
-
143
-
-
84975188332
-
A randomized phase II trial of the MET inhibitor tivantinib + cetuximab versus cetuximab alone in patients with recurrent/metastatic head and neck cancer
-
Vokes EE, Worden FP, Adkins D, Bauman JE, Lim D, Sukari A et al. A randomized phase II trial of the MET inhibitor tivantinib + cetuximab versus cetuximab alone in patients with recurrent/metastatic head and neck cancer. J Clin Oncol 2015; 33: 6060.
-
(2015)
J Clin Oncol
, vol.33
, pp. 6060
-
-
Vokes, E.E.1
Worden, F.P.2
Adkins, D.3
Bauman, J.E.4
Lim, D.5
Sukari, A.6
-
144
-
-
84992395983
-
Phase II randomized, double-blind, placebo controlled study of tivantinib in men with asymptomatic or minimally symptomatic metastatic castrate-resistant prostate cancer (mCRPC)
-
Monk P, Liu G, Stadler WM, Geyer SM, Sexton JL, Wright JJ et al. Phase II randomized, double-blind, placebo controlled study of tivantinib in men with asymptomatic or minimally symptomatic metastatic castrate-resistant prostate cancer (mCRPC). J Clin Oncol 2015; 33: 146.
-
(2015)
J Clin Oncol
, vol.33
, pp. 146
-
-
Monk, P.1
Liu, G.2
Stadler, W.M.3
Geyer, S.M.4
Sexton, J.L.5
Wright, J.J.6
-
145
-
-
84911947734
-
Phase II study of erlotinib plus tivantinib in patients with RGFR-mutation-positive NSCLC who failed in immediately previuos EGFR-TKI therapy
-
Hirashima T, Azuma K, Yamamoto N, Takahashi T, Nishio M et al. Phase II study of erlotinib plus tivantinib in patients with RGFR-mutation-positive NSCLC who failed in immediately previuos EGFR-TKI therapy. J Clin Oncol 2014; 32: 8052.
-
(2014)
J Clin Oncol
, vol.32
, pp. 8052
-
-
Hirashima, T.1
Azuma, K.2
Yamamoto, N.3
Takahashi, T.4
Nishio, M.5
-
146
-
-
84941979076
-
The c-Met Tyrosine Kinase Inhibitor JNJ-38877605 Causes Renal Toxicity through Species-Specific Insoluble Metabolite Formation
-
Lolkema MP, Bohets HH, Arkenau HT, Lampo A, Barale E, de Jonge MJ et al. The c-Met Tyrosine Kinase Inhibitor JNJ-38877605 Causes Renal Toxicity through Species-Specific Insoluble Metabolite Formation. Clin Cancer Res 2015; 21: 2297-2304.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 2297-2304
-
-
Lolkema, M.P.1
Bohets, H.H.2
Arkenau, H.T.3
Lampo, A.4
Barale, E.5
De Jonge, M.J.6
-
147
-
-
84992430663
-
Phase i study of INC280 plus erlotinib in patients with MET expressing adenocarcinoma of the lung
-
McCoach CE, Yu A, Gandara DR, Riess J, Li T, Lara P et al. Phase I study of INC280 plus erlotinib in patients with MET expressing adenocarcinoma of the lung. J Clin Oncol 2015; 33: 2587.
-
(2015)
J Clin Oncol
, vol.33
, pp. 2587
-
-
McCoach, C.E.1
Yu, A.2
Gandara, D.R.3
Riess, J.4
Li, T.5
Lara, P.6
-
148
-
-
84914179300
-
Phase i study of the safety and efficacy of INC280 in patients with advanced MET-dependent solid tumors
-
Bang Y-J, Su W-C, Nam D-Y, Lim W-T, Bauer TM, Brana I et al. Phase I study of the safety and efficacy of INC280 in patients with advanced MET-dependent solid tumors. J Clin Oncol 2014; 32: 2520.
-
(2014)
J Clin Oncol
, vol.32
, pp. 2520
-
-
Bang, Y.-J.1
Su, W.-C.2
Nam, D.-Y.3
Lim, W.-T.4
Bauer, T.M.5
Brana, I.6
-
149
-
-
84916940426
-
First in human study of AMG 337, a highly selective oral inhibitor of MET, in adult patients with advanced solid tumors
-
Hong DS, LoRusso P, Hamid O, Beaupre DM, Janku F, Khan R et al. First in human study of AMG 337, a highly selective oral inhibitor of MET, in adult patients with advanced solid tumors. J Clin Oncol 2014; 32: 2508.
-
(2014)
J Clin Oncol
, vol.32
, pp. 2508
-
-
Hong, D.S.1
LoRusso, P.2
Hamid, O.3
Beaupre, D.M.4
Janku, F.5
Khan, R.6
-
150
-
-
84930635677
-
Clinical activity of AMG 337, an oral MET kinase inhibitor, in adult patients with METamplified gastro-esophageal junction, gastric or esophageal cancer
-
Kwak EL, LoRusso P, Hamid O, Janku F, Kittaneh M, Catenacci DVT et al. Clinical activity of AMG 337, an oral MET kinase inhibitor, in adult patients with METamplified gastro-esophageal junction, gastric or esophageal cancer. J Clin Oncol 2015; 33: 1.
-
(2015)
J Clin Oncol
, vol.33
, pp. 1
-
-
Kwak, E.L.1
LoRusso, P.2
Hamid, O.3
Janku, F.4
Kittaneh, M.5
Catenacci, D.V.T.6
-
151
-
-
84998894012
-
Efficacy, safefy, biomarkers and phase II dose modeling in a phase i trial of the oral selective c-MET inhibitor tepotinib (MSC2156119J)
-
Falchook GS, Kurzrock R, Amin HM, Fu S, Piha-Paul SA, Janku F et al. Efficacy, safefy, biomarkers and phase II dose modeling in a phase I trial of the oral selective c-MET inhibitor tepotinib (MSC2156119J). J Clin Oncol 2015; 33: 2591.
-
(2015)
J Clin Oncol
, vol.33
, pp. 2591
-
-
Falchook, G.S.1
Kurzrock, R.2
Amin, H.M.3
Fu, S.4
Piha-Paul, S.A.5
Janku, F.6
-
152
-
-
84938800976
-
A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors
-
Hong DS, Rosen P, Lockhart AC, Fu S, Janku F, Kurzrock R et al. A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors. Oncotarget 2015; 6: 18693-18706.
-
(2015)
Oncotarget
, vol.6
, pp. 18693-18706
-
-
Hong, D.S.1
Rosen, P.2
Lockhart, A.C.3
Fu, S.4
Janku, F.5
Kurzrock, R.6
-
153
-
-
84914095781
-
First-in-human phase i study of a selective c-Met inhibitor volitinib (HMP504/AZD6094) in patients with advanced solid tumors
-
Gan HK, Lickliter J, Millward M, Gu Y, SU W, Frigault M et al. First-in-human phase I study of a selective c-Met inhibitor volitinib (HMP504/AZD6094) in patients with advanced solid tumors. J Clin Oncol 2014; 32: 11111.
-
(2014)
J Clin Oncol
, vol.32
, pp. 11111
-
-
Gan, H.K.1
Lickliter, J.2
Millward, M.3
Gu, Y.4
Su, W.5
Frigault, M.6
-
154
-
-
84896514016
-
Phase i dose-escalation study of onartuzumab as a single agent and in combination with bevacizumab in patients with advanced solid malignancies
-
Salgia R, Patel P, Bothos J, Yu W, Eppler S, Hegde P et al. Phase I dose-escalation study of onartuzumab as a single agent and in combination with bevacizumab in patients with advanced solid malignancies. Clin Cancer Res 2014; 20: 1666-1675.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 1666-1675
-
-
Salgia, R.1
Patel, P.2
Bothos, J.3
Yu, W.4
Eppler, S.5
Hegde, P.6
-
155
-
-
84905011727
-
Biomarker analyses from a placebo-controlled phase II study evaluating erlotinib+/-onartuzumab in advanced non-small cell lung cancer: MET expression levels are predictive of patient benefit
-
Koeppen H, Yu W, Zha J, Pandita A, Penuel E, Rangell L et al. Biomarker analyses from a placebo-controlled phase II study evaluating erlotinib+/-onartuzumab in advanced non-small cell lung cancer: MET expression levels are predictive of patient benefit. Clin Cancer Res 2014; 20: 4488-4498.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 4488-4498
-
-
Koeppen, H.1
Yu, W.2
Zha, J.3
Pandita, A.4
Penuel, E.5
Rangell, L.6
-
156
-
-
84941643538
-
Randomized, phase II, placebo-controlled trial of onartuzumab and/or bevacizumab in combination with weekly paclitaxel in patients with metastatic triple-negative breast cancer
-
Dieras V, Campone M, Yardley DA, Romieu G, Valero V, Isakoff SJ et al. Randomized, phase II, placebo-controlled trial of onartuzumab and/or bevacizumab in combination with weekly paclitaxel in patients with metastatic triple-negative breast cancer. Ann Oncol 2015; 26: 1904-1910.
-
(2015)
Ann Oncol
, vol.26
, pp. 1904-1910
-
-
Dieras, V.1
Campone, M.2
Yardley, D.A.3
Romieu, G.4
Valero, V.5
Isakoff, S.J.6
-
157
-
-
84992357897
-
Onartuzumab plus bevacizumab versus placebo plus bevacizumab in recurrent glioblastoma: HGF and MGMT biomarker data
-
Cloughesy TF, Finocchiaro G, Belda C, Recht L, Brandes AA, Pineda E et al. Onartuzumab plus bevacizumab versus placebo plus bevacizumab in recurrent glioblastoma: HGF and MGMT biomarker data. J Clin Oncol 2015; 33: 2015.
-
(2015)
J Clin Oncol
, vol.33
, pp. 2015
-
-
Cloughesy, T.F.1
Finocchiaro, G.2
Belda, C.3
Recht, L.4
Brandes, A.A.5
Pineda, E.6
-
158
-
-
84930647803
-
Randomized phase II study of FOLFOX +/? MET inhibitor, onartuzumab (O), in advanced gastroesophageal adenocarcinoma (GEC)
-
Shah MA, Cho JY, Huat ITB, Tebbutt NC, Yen CJ, Kang A et al. Randomized phase II study of FOLFOX +/? MET inhibitor, onartuzumab (O), in advanced gastroesophageal adenocarcinoma (GEC). J Clin Oncol 2015; 33: 2.
-
(2015)
J Clin Oncol
, vol.33
, pp. 2
-
-
Shah, M.A.1
Cho, J.Y.2
Huat, I.T.B.3
Tebbutt, N.C.4
Yen, C.J.5
Kang, A.6
-
159
-
-
84948680699
-
A Randomized, double-blind, phase II study of first-line FOLFOX plus bevacizumab with onartuzumab versus placebo in patients with metastatic colorectal cancer (mCRC)
-
Bendell JC, Hochster HS, Hart LL, Firdaus I, Mace JR, McFarlane JJ et al. A Randomized, double-blind, phase II study of first-line FOLFOX plus bevacizumab with onartuzumab versus placebo in patients with metastatic colorectal cancer (mCRC). J Clin Oncol 2015; 33: 663.
-
(2015)
J Clin Oncol
, vol.33
, pp. 663
-
-
Bendell, J.C.1
Hochster, H.S.2
Hart, L.L.3
Firdaus, I.4
Mace, J.R.5
McFarlane, J.J.6
-
160
-
-
84989872326
-
Onartuzumab plus erlotinib versus erlotinib in previously treated stage lllb or IV NSCLC: Results from the pivotal phase III randomized, multicenter, placebo-controlled METlung (OAM4971g) global trial
-
Spigel DR, Edelman MJ, O'Byrne K, Paz-Ares L, Shames Ds, Yu W et al. Onartuzumab plus erlotinib versus erlotinib in previously treated stage lllb or IV NSCLC: Results from the pivotal phase III randomized, multicenter, placebo-controlled METlung (OAM4971g) global trial. J Clin Oncol 2014; 32: 8000.
-
(2014)
J Clin Oncol
, vol.32
, pp. 8000
-
-
Spigel, D.R.1
Edelman, M.J.2
O'Byrne, K.3
Paz-Ares, L.4
Ds, S.5
Yu, W.6
-
161
-
-
84940608924
-
MetGastric: A phase III study of onartuzumab plus mFOLFOX6 in patients with metastatic HER2-negative and MET-positive adenocarcinoma of the stomach or gastroesophageal junction
-
Shah MA, Bang YJ, Lordick F, Tabernero J, Chen M, Hack SP et al. MetGastric: A phase III study of onartuzumab plus mFOLFOX6 in patients with metastatic HER2-negative and MET-positive adenocarcinoma of the stomach or gastroesophageal junction. J Clin Oncol 2015; vol. 33: 4012.
-
(2015)
J Clin Oncol
, vol.33
, pp. 4012
-
-
Shah, M.A.1
Bang, Y.J.2
Lordick, F.3
Tabernero, J.4
Chen, M.5
Hack, S.P.6
-
162
-
-
84947444749
-
A phase I, first in human study of ARGX-111, a monoclonal antibody targeting c-MET in patients with solid tulors
-
Aftimos PG, Barthelemy P, Rolfo CD, Hanssens V, Jonge ND, Silence K et al. A phase I, first in human study of ARGX-111, a monoclonal antibody targeting c-MET in patients with solid tulors. J Clin Oncol 2015; 33: 2580.
-
(2015)
J Clin Oncol
, vol.33
, pp. 2580
-
-
Aftimos, P.G.1
Barthelemy, P.2
Rolfo, C.D.3
Hanssens, V.4
Jonge, N.D.5
Silence, K.6
-
163
-
-
84938780004
-
Phase I, open label, dose-escalation, and expansion study of ABT-700, an anti C-MET antibody, in patients with advanced solid tumors
-
Strickler JH, LoRusso P, Yen C-J, Lin C-C, Kang Y-K, Kaminker P et al. Phase I, open label, dose-escalation, and expansion study of ABT-700, an anti C-MET antibody, in patients with advanced solid tumors. J Clin Oncol 2014; 32: 2507.
-
(2014)
J Clin Oncol
, vol.32
, pp. 2507
-
-
Strickler, J.H.1
LoRusso, P.2
Yen, C.-J.3
Lin, C.-C.4
Kang, Y.-K.5
Kaminker, P.6
-
164
-
-
84942195118
-
Phase i study of ABT-700, an anti-c-MET antibody in patients with advanced gastric or esophageal cancer2015 ASCO GI Meeting
-
Kang YK, LoRusso P, Salgia R, Yen C-J, Ramanathan RK, Kaminker P et al. Phase I study of ABT-700, an anti-c-MET antibody in patients with advanced gastric or esophageal cancer2015 ASCO GI Meeting. J Clin Oncol 2015; 33: 167.
-
(2015)
J Clin Oncol
, vol.33
, pp. 167
-
-
Kang, Y.K.1
LoRusso, P.2
Salgia, R.3
Yen, C.-J.4
Ramanathan, R.K.5
Kaminker, P.6
-
165
-
-
84901068637
-
A pharmacodynamic/pharmacokinetic study of ficlatuzumab in patients with advanced solid tumors and liver metastases
-
Tabernero J, Elez ME, Herranz M, Rico I, Prudkin L, Andreu J et al. A pharmacodynamic/pharmacokinetic study of ficlatuzumab in patients with advanced solid tumors and liver metastases. Clin Cancer Res 2014; 20: 2793-2804.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 2793-2804
-
-
Tabernero, J.1
Elez, M.E.2
Herranz, M.3
Rico, I.4
Prudkin, L.5
Andreu, J.6
-
166
-
-
84904542906
-
Phase i ficlatuzumab monotherapy or with erlotinib for refractory advanced solid tumours and multiple myeloma
-
Patnaik A, Weiss GJ, Papadopoulos KP, Hofmeister CC, Tibes R, Tolcher A et al. Phase I ficlatuzumab monotherapy or with erlotinib for refractory advanced solid tumours and multiple myeloma. Br J Cancer 2014; 111: 272-280.
-
(2014)
Br J Cancer
, vol.111
, pp. 272-280
-
-
Patnaik, A.1
Weiss, G.J.2
Papadopoulos, K.P.3
Hofmeister, C.C.4
Tibes, R.5
Tolcher, A.6
|