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Volumn 101, Issue 9, 1998, Pages 1827-1834

Hepatocyte growth factor prevents renal fibrosis and dysfunction in a mouse model of chronic renal disease

Author keywords

Chronic renal failure; Glomerulosclerosis; HGF therapy; Kidney; Tubular proliferation

Indexed keywords

SCATTER FACTOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 0032080835     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI1709     Document Type: Article
Times cited : (238)

References (48)
  • 1
    • 0002261852 scopus 로고    scopus 로고
    • Hemodialysis
    • B.M. Brenner, editor. W.B. Saunders, Philadelphia
    • Lazarus, J.M., B.M. Denker, and W.F. Owen. 1996. Hemodialysis. In The Kidney 5th Ed. B.M. Brenner, editor. W.B. Saunders, Philadelphia. 2424-2506.
    • (1996) The Kidney 5th Ed. , pp. 2424-2506
    • Lazarus, J.M.1    Denker, B.M.2    Owen, W.F.3
  • 2
    • 0020324688 scopus 로고
    • Dietary protein intake and the progressive nature of kidney disease: The role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease
    • Brenner, B.M., T.W. Meyer, and T.H. Hostetter. 1982. Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease. N. Engl. J. Med. 307:652-659.
    • (1982) N. Engl. J. Med. , vol.307 , pp. 652-659
    • Brenner, B.M.1    Meyer, T.W.2    Hostetter, T.H.3
  • 3
    • 0028069634 scopus 로고
    • Loss of glomerular function and tubulointerstitial fibrosis: Cause or effect?
    • Ong, A.C., and L.G. Fine. 1994. Loss of glomerular function and tubulointerstitial fibrosis: cause or effect? Kidney Int. 45:345-351.
    • (1994) Kidney Int. , vol.45 , pp. 345-351
    • Ong, A.C.1    Fine, L.G.2
  • 4
    • 0014421532 scopus 로고
    • Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis
    • Risdon, R.A., J.C. Sloper, and H.E. Wardener. 1968. Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis. Lancet. 2:363-366.
    • (1968) Lancet , vol.2 , pp. 363-366
    • Risdon, R.A.1    Sloper, J.C.2    Wardener, H.E.3
  • 5
    • 0028334128 scopus 로고
    • On the pathogenesis of chronic renal failure in primary glomerulopathies: A view from the interstitium
    • Bohle, A., F. Strutz, and G.A. Muller. 1994. On the pathogenesis of chronic renal failure in primary glomerulopathies: a view from the interstitium. Exp. Nephrol 2:205-210.
    • (1994) Exp. Nephrol , vol.2 , pp. 205-210
    • Bohle, A.1    Strutz, F.2    Muller, G.A.3
  • 6
    • 0030419494 scopus 로고    scopus 로고
    • Molecular insights into renal interstitial fibrosis
    • Eddy, A.A. 1996. Molecular insights into renal interstitial fibrosis. J. Am. Soc. Nephrol. 7:2495-2508.
    • (1996) J. Am. Soc. Nephrol. , vol.7 , pp. 2495-2508
    • Eddy, A.A.1
  • 7
    • 0029945622 scopus 로고    scopus 로고
    • Mechanisms involved in the pathogenesis of tubulointerstitial fibrosis in 5/6-nephrectomized rats
    • Kliem, V., R.J. Johnson, C.E. Alpers, A. Yoshimura, W.G. Couser, K.M. Koch, and J. Floege. 1996. Mechanisms involved in the pathogenesis of tubulointerstitial fibrosis in 5/6-nephrectomized rats. Kidney Int. 49:666-678.
    • (1996) Kidney Int. , vol.49 , pp. 666-678
    • Kliem, V.1    Johnson, R.J.2    Alpers, C.E.3    Yoshimura, A.4    Couser, W.G.5    Koch, K.M.6    Floege, J.7
  • 8
    • 0030903307 scopus 로고    scopus 로고
    • RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis
    • Lloyd, C.M., A.W. Minto, M.E. Dorf, A. Proudfoot, T.N.C. Wells, D.J. Salant, and J.C. Gutierrez-Ramos. 1997. RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis. J Exp. Med. 185:1371-1380.
    • (1997) J Exp. Med. , vol.185 , pp. 1371-1380
    • Lloyd, C.M.1    Minto, A.W.2    Dorf, M.E.3    Proudfoot, A.4    Wells, T.N.C.5    Salant, D.J.6    Gutierrez-Ramos, J.C.7
  • 9
    • 0028932953 scopus 로고
    • Progression of renal disease and renal hypertrophy
    • Hostetter, T.H. 1995. Progression of renal disease and renal hypertrophy. Annu. Rev. Physiol. 57:263-278.
    • (1995) Annu. Rev. Physiol. , vol.57 , pp. 263-278
    • Hostetter, T.H.1
  • 13
    • 0025824738 scopus 로고
    • Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor
    • Montesano, R., K. Matsumoto, T. Nakamura, and L. Orci. 1991. Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell. 67:901-908.
    • (1991) Cell , vol.67 , pp. 901-908
    • Montesano, R.1    Matsumoto, K.2    Nakamura, T.3    Orci, L.4
  • 14
    • 0026323274 scopus 로고
    • Renotropic functions of hepatocyte growth factor in renal regeneration after unilateral nephrectomy
    • Nagaike, M., S. Hirao, H. Tajima, S. Noji, S. Taniguchi, K. Matsumoto, and T. Nakamura. 1991. Renotropic functions of hepatocyte growth factor in renal regeneration after unilateral nephrectomy. J. Biol. Chem. 266:22781-22784.
    • (1991) J. Biol. Chem. , vol.266 , pp. 22781-22784
    • Nagaike, M.1    Hirao, S.2    Tajima, H.3    Noji, S.4    Taniguchi, S.5    Matsumoto, K.6    Nakamura, T.7
  • 15
    • 0028049013 scopus 로고
    • Regional expression of hepatocyte growth factor/c-met in experimental renal hypertrophy and hyperplasia
    • Joannidis, M., K. Spokes, T. Nakamura, D. Faletto, and L.G. Cantley. 1994. Regional expression of hepatocyte growth factor/c-met in experimental renal hypertrophy and hyperplasia. Am. J. Physiol. 267:F231-F236.
    • (1994) Am. J. Physiol. , vol.267
    • Joannidis, M.1    Spokes, K.2    Nakamura, T.3    Faletto, D.4    Cantley, L.G.5
  • 16
    • 0028210134 scopus 로고
    • Hepatocyte growth factor prevents acute renal failure and accelerates renal regeneration in mice
    • Kawaida, K., K. Matsumoto, H. Shimazu, and T. Nakamura. 1994. Hepatocyte growth factor prevents acute renal failure and accelerates renal regeneration in mice. Proc. Natl. Acad. Sci. USA. 91:4357-4361.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4357-4361
    • Kawaida, K.1    Matsumoto, K.2    Shimazu, H.3    Nakamura, T.4
  • 17
    • 0028154033 scopus 로고
    • Hepatocyte growth factor accelerates recovery from acute ischemic renal injury in rats
    • Miller, S.B., D.R. Martin, J. Kissane, and M.R. Hammerman. 1994. Hepatocyte growth factor accelerates recovery from acute ischemic renal injury in rats. Am. J. Physiol. 266:F129-F134.
    • (1994) Am. J. Physiol. , vol.266
    • Miller, S.B.1    Martin, D.R.2    Kissane, J.3    Hammerman, M.R.4
  • 18
    • 0003408235 scopus 로고
    • Nephrosis (nep): A new mouse mutation which causes albuminuria and other symptoms of nephrosis
    • Kurosawa, T., M. Okamoto, K. Yamada, and B.F. Yue. 1993. Nephrosis (nep): a new mouse mutation which causes albuminuria and other symptoms of nephrosis. Mouse Genome. 91:876-879.
    • (1993) Mouse Genome. , vol.91 , pp. 876-879
    • Kurosawa, T.1    Okamoto, M.2    Yamada, K.3    Yue, B.F.4
  • 19
    • 0028075355 scopus 로고
    • Hereditary nephrotic syndrome with progression to renal failure in a mouse model (ICON strain): Clinical study
    • Ogura, A., T. Asano, O. Suzuki, Y. Yamamoto, Y. Noguchi, H. Kawaguchi and Y. Yamaguchi. 1994. Hereditary nephrotic syndrome with progression to renal failure in a mouse model (ICON strain): clinical study. Nephron. 68:239-244.
    • (1994) Nephron. , vol.68 , pp. 239-244
    • Ogura, A.1    Asano, T.2    Suzuki, O.3    Yamamoto, Y.4    Noguchi, Y.5    Kawaguchi, H.6    Yamaguchi, Y.7
  • 20
    • 0031455209 scopus 로고    scopus 로고
    • Diffuse glomerulosclerosis without tubular injury does not directly manifest renal dysfunction in nephrotic mice (ICGN strain)
    • Mizuno, S., B.F. Yue, M. Okamoto, Y. Horikawa, and T. Kurosawa. 1997. Diffuse glomerulosclerosis without tubular injury does not directly manifest renal dysfunction in nephrotic mice (ICGN strain). Exp. Nephrol. 5:498-507.
    • (1997) Exp. Nephrol. , vol.5 , pp. 498-507
    • Mizuno, S.1    Yue, B.F.2    Okamoto, M.3    Horikawa, Y.4    Kurosawa, T.5
  • 21
    • 0028280372 scopus 로고
    • Hepatocyte growth factor and its variant with a deletion of five amino acids are distinguishable in their biological activity and tertiary structure
    • Shima, N., E. Tsuda, M. Goto, K. Yano, H. Hayasaka, M. Ueda, and K. Higashio. 1994. Hepatocyte growth factor and its variant with a deletion of five amino acids are distinguishable in their biological activity and tertiary structure. Biochem. Biophys. Res. Commun. 200:808-815.
    • (1994) Biochem. Biophys. Res. Commun. , vol.200 , pp. 808-815
    • Shima, N.1    Tsuda, E.2    Goto, M.3    Yano, K.4    Hayasaka, H.5    Ueda, M.6    Higashio, K.7
  • 22
    • 0021179653 scopus 로고
    • Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats
    • Raij, L., S. Azar, and W. Keane. 1984. Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats. Kidney Int. 26:137-143.
    • (1984) Kidney Int. , vol.26 , pp. 137-143
    • Raij, L.1    Azar, S.2    Keane, W.3
  • 26
    • 0026792940 scopus 로고
    • Cell density-dependent regulation of albumin synthesis and DNA synthesis in rat hepatocytes by hepatocyte growth factor
    • Takehara, T., K. Matsumoto, and T. Nakamura. 1992. Cell density-dependent regulation of albumin synthesis and DNA synthesis in rat hepatocytes by hepatocyte growth factor. J. Biachem. 112:330-334.
    • (1992) J. Biachem. , vol.112 , pp. 330-334
    • Takehara, T.1    Matsumoto, K.2    Nakamura, T.3
  • 27
    • 0029146465 scopus 로고
    • Hepatocyte growth factor suppresses the onset of liver cirrhosis and abrogates lethal hepatic dysfunction in rats
    • Matsuda, Y., K. Matsumoto, T. Ichida, and T. Nakamura. 1995. Hepatocyte growth factor suppresses the onset of liver cirrhosis and abrogates lethal hepatic dysfunction in rats. J. Biochem. 118:643-649.
    • (1995) J. Biochem. , vol.118 , pp. 643-649
    • Matsuda, Y.1    Matsumoto, K.2    Ichida, T.3    Nakamura, T.4
  • 28
    • 0029869237 scopus 로고    scopus 로고
    • Platelet-derived growth factor-BB induces renal tubulointerstitial myofibroblast formation and tubulointerstitial fibrosis
    • Tang, W.W., T.R. Ulich, D.L. Lacey, D.C. Hill, M. Qi, S.A. Kaufman, G.Y. Van, J.E. Tarpley, and J.S. Yee. 1996. Platelet-derived growth factor-BB induces renal tubulointerstitial myofibroblast formation and tubulointerstitial fibrosis. Am. J. Pathol. 148:1169-1180.
    • (1996) Am. J. Pathol. , vol.148 , pp. 1169-1180
    • Tang, W.W.1    Ulich, T.R.2    Lacey, D.L.3    Hill, D.C.4    Qi, M.5    Kaufman, S.A.6    Van, G.Y.7    Tarpley, J.E.8    Yee, J.S.9
  • 29
    • 0028109801 scopus 로고
    • Transforming growth factor beta in tissue fibrosis
    • Border, W.A., and N.A. Noble. 1994. Transforming growth factor beta in tissue fibrosis. N. Engl. J. Med. 331:1286-1292.
    • (1994) N. Engl. J. Med. , vol.331 , pp. 1286-1292
    • Border, W.A.1    Noble, N.A.2
  • 30
    • 2642703899 scopus 로고    scopus 로고
    • ACE inhibitor suppresses tubular expression of PDGF and attenuates progression of tubulo-interstitial fibrosis in a nephrotic mouse model
    • In press
    • Mizuno, S., Y. Mizuno-Horikawa, M. Okamoto, and T. Kurosawa. 1998. ACE inhibitor suppresses tubular expression of PDGF and attenuates progression of tubulo-interstitial fibrosis in a nephrotic mouse model. Nephron. In press.
    • (1998) Nephron.
    • Mizuno, S.1    Mizuno-Horikawa, Y.2    Okamoto, M.3    Kurosawa, T.4
  • 32
    • 0028999868 scopus 로고
    • The many faces of hepatocyte growth factor from hepatopoiesis to hematopoiesis
    • Zarnegar, R., and G.K. Michalopoulos. 1995. The many faces of hepatocyte growth factor from hepatopoiesis to hematopoiesis. J. Cell Biol. 129:1177-1180.
    • (1995) J. Cell Biol. , vol.129 , pp. 1177-1180
    • Zarnegar, R.1    Michalopoulos, G.K.2
  • 33
    • 0026484294 scopus 로고
    • Direct evidence that hepatocyte growth factor is a hepatotrophic factor for liver regeneration and has a potent antihepatitis effect in vivo
    • Ishiki, Y., H. Ohnishi, Y. Muto, K. Matsumoto, and T. Nakamura. 1992. Direct evidence that hepatocyte growth factor is a hepatotrophic factor for liver regeneration and has a potent antihepatitis effect in vivo. Hepatology. 16:1227-1235.
    • (1992) Hepatology , vol.16 , pp. 1227-1235
    • Ishiki, Y.1    Ohnishi, H.2    Muto, Y.3    Matsumoto, K.4    Nakamura, T.5
  • 34
    • 0029817895 scopus 로고    scopus 로고
    • Antifibrogenic effect of a deletion variant of hepatocyte growth factor on liver fibrosis in rats
    • Yasuda, H., E. Imai, A. Shiota, N. Fujise, T. Morinaga, and K. Higashio. 1996. Antifibrogenic effect of a deletion variant of hepatocyte growth factor on liver fibrosis in rats. Hepatology. 24:636-642.
    • (1996) Hepatology , vol.24 , pp. 636-642
    • Yasuda, H.1    Imai, E.2    Shiota, A.3    Fujise, N.4    Morinaga, T.5    Higashio, K.6
  • 36
    • 14444271598 scopus 로고    scopus 로고
    • Simultaneous or delayed administration of hepatocyte growth factor (HGF) equally repress the fibrotic changes in murine lung injury by bleomycin: A morphological study
    • Yaekashi, M., S. Nakamura, K. Ohnuma, T. Sasaki, T. Abe, K. Satoh, K. Matsumoto, T. Nakamura, T. Takahashi, and T. Nukiwa. 1997. Simultaneous or delayed administration of hepatocyte growth factor (HGF) equally repress the fibrotic changes in murine lung injury by bleomycin: a morphological study. Am. J. Respir. Clin. Care Med. 156:1937-1944.
    • (1997) Am. J. Respir. Clin. Care Med. , vol.156 , pp. 1937-1944
    • Yaekashi, M.1    Nakamura, S.2    Ohnuma, K.3    Sasaki, T.4    Abe, T.5    Satoh, K.6    Matsumoto, K.7    Nakamura, T.8    Takahashi, T.9    Nukiwa, T.10
  • 37
    • 0026601840 scopus 로고
    • Hepatocyte growth factor is a paracrine factor for renal epithelial cells: Stimulation of DNA synthesis and Na,K-ATPase activity
    • Ishibashi, K., S. Sasaki, H. Sakamoto, Y. Nakamura, T. Hata, T. Nakamura, and F. Marumo. 1992. Hepatocyte growth factor is a paracrine factor for renal epithelial cells: stimulation of DNA synthesis and Na,K-ATPase activity. Biochem. Biophys. Res. Commun. 182:960-965.
    • (1992) Biochem. Biophys. Res. Commun. , vol.182 , pp. 960-965
    • Ishibashi, K.1    Sasaki, S.2    Sakamoto, H.3    Nakamura, Y.4    Hata, T.5    Nakamura, T.6    Marumo, F.7
  • 38
    • 0029050634 scopus 로고
    • Differential lubulogenic and branching morphogenetic activities of growth factors: Implications for epithelial tissue development
    • Barrow, E.J.G., O.F.T. Santos, K. Matsumoto, T. Nakamura, and S.K. Nigam. 1995. Differential lubulogenic and branching morphogenetic activities of growth factors: implications for epithelial tissue development. Proc. Natl. Acad. Sci. USA. 92:4412-4416.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 4412-4416
    • Barrow, E.J.G.1    Santos, O.F.T.2    Matsumoto, K.3    Nakamura, T.4    Nigam, S.K.5
  • 39
    • 0027437547 scopus 로고
    • Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development
    • Sonnenberg, E., D. Meyer, K.M. Weidner, and C. Birchmeier. 1993. Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development. J. Cell Biol. 123:223-235.
    • (1993) J. Cell Biol. , vol.123 , pp. 223-235
    • Sonnenberg, E.1    Meyer, D.2    Weidner, K.M.3    Birchmeier, C.4
  • 41
    • 0029967390 scopus 로고    scopus 로고
    • Phenotypic modulation of renal cells during experimental and clinical renal scarring
    • Nahas, A.M.E., K.E. Muchaneta, G. Zhang, A. Adam, and D. Goumenos. 1996. Phenotypic modulation of renal cells during experimental and clinical renal scarring. Kidney Int. 49(Suppl.):S23-S27.
    • (1996) Kidney Int. , vol.49 , Issue.SUPPL.
    • Nahas, A.M.E.1    Muchaneta, K.E.2    Zhang, G.3    Adam, A.4    Goumenos, D.5
  • 42
    • 0028493140 scopus 로고
    • Human renal cortical cells with some features of smooth muscle cells participate in tubulointerstitial and crescentic glomerular injury
    • Alpers, C.E., K.L. Hudkins, J. Floege, and R.J. Johnson. 1994. Human renal cortical cells with some features of smooth muscle cells participate in tubulointerstitial and crescentic glomerular injury. J. Am. Soc. Nephrol. 5:201-210.
    • (1994) J. Am. Soc. Nephrol. , vol.5 , pp. 201-210
    • Alpers, C.E.1    Hudkins, K.L.2    Floege, J.3    Johnson, R.J.4
  • 44
    • 0027138877 scopus 로고
    • Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney
    • Isaka, Y., Y. Fujiwara, N. Ueda, Y. Kaneda, T. Kamada, and E. Imai. 1993. Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney. J. Clin. Invest. 92:2597-2601.
    • (1993) J. Clin. Invest. , vol.92 , pp. 2597-2601
    • Isaka, Y.1    Fujiwara, Y.2    Ueda, N.3    Kaneda, Y.4    Kamada, T.5    Imai, E.6
  • 45
    • 0029905441 scopus 로고    scopus 로고
    • Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney
    • Isaka, Y., D.K. Brees, K. Ikegaya, Y. Kaneda, E. Imai, N.A. Noble, and W.A. Border. 1996. Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney. Nature Med. 2:418-423.
    • (1996) Nature Med. , vol.2 , pp. 418-423
    • Isaka, Y.1    Brees, D.K.2    Ikegaya, K.3    Kaneda, Y.4    Imai, E.5    Noble, N.A.6    Border, W.A.7
  • 46
    • 0026562550 scopus 로고
    • Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor
    • Johnson, R.J., E.W. Raines, J. Floege, A. Yoshimura, P. Pritzl, C. Alpers, and R. Ross. 1992. Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor. J Exp. Med. 175:1413-1416.
    • (1992) J Exp. Med. , vol.175 , pp. 1413-1416
    • Johnson, R.J.1    Raines, E.W.2    Floege, J.3    Yoshimura, A.4    Pritzl, P.5    Alpers, C.6    Ross, R.7
  • 47
    • 0030738188 scopus 로고    scopus 로고
    • Renal tubular hyperplasia, polycystic disease, and glomerulosclerosis in transgenic mice overexpressing hepatocyte growth factor/scatter factor
    • Takayama, H., W.J. LaRochelle, S.G. Sabnis, T. Otsuka, and G. Merlino. 1997. Renal tubular hyperplasia, polycystic disease, and glomerulosclerosis in transgenic mice overexpressing hepatocyte growth factor/scatter factor. Lab. Invest. 77:131-138.
    • (1997) Lab. Invest. , vol.77 , pp. 131-138
    • Takayama, H.1    LaRochelle, W.J.2    Sabnis, S.G.3    Otsuka, T.4    Merlino, G.5
  • 48
    • 0028213841 scopus 로고
    • Hepatocyte growth factor in transgenic mice: Effects on hepatocyte growth factor, liver generation and gene expression
    • Shiota, G., T.C. Wang, T. Nakamura, and E.V. Schmidt. 1994. Hepatocyte growth factor in transgenic mice: effects on hepatocyte growth factor, liver generation and gene expression. Hepatology. 19:962-972.
    • (1994) Hepatology , vol.19 , pp. 962-972
    • Shiota, G.1    Wang, T.C.2    Nakamura, T.3    Schmidt, E.V.4


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