Hepatocyte growth factor ameliorates acute graft-versus-host disease and promotes hematopoietic function

Journal of Clinical Investigation

Volumn 107, Issue 11, 2001, Pages 1365-1373

  Kuroiwa, Takanori ^a   Kakishita, Eizo ^a   Hamano, Teruaki ^a   Kataoka, Yasuro ^a   Seto, Yoshifumi ^a   Iwata, Nobuo ^a   Kaneda, Yasufumi ^b   Matsumoto, Kunio ^b   Nakamura, Toshikazu ^b   Ueki, Takahiro ^a   Fujimoto, Jiro ^a   Iwasaki, Tsuyoshi ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12; RNA; SCATTER FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MARROW TRANSPLANTATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE TRANSFER; GRAFT VERSUS HOST REACTION; HEMATOPOIESIS; INTESTINE; LIVER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL;

EID: 0034987974     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI11808     Document Type: Article

References (35)

1. Depletion of T lymphocytes in donor marrow prevents significant graft-versus-host disease in matched allogeneic leukemic marrow transplant recipients
2. Bone marrow transplantation
3. Graft-versus-host disease: Pathophysiological and clinical aspects
4. Graft-versus-host disease
5. Effects of in vivo depletion of T cells in HLA-identical allogeneic marrow grafts
6. Total body irradiation and acute graft-versus-host disease: The role of gastrointestinal damage and inflammatory cytokines
7. Graft-versus-host disease of the liver
8. Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats
9. Molecular cloning and expression of human hepatocyte growth factor
10. Hepatocyte growth factor prevents acute renal failure and accelerates renal regeneration in mice
11. In vivo mitogenic action of HGF on lung epithelial cells: Pulmotrophic role in lung regeneration
12. Influence of luminar hepatocyte growth factor on small intestine mucosa in vivo
13. HGF receptor associates with anti-apoptotic protein BAG-1 and prevents cell death
14. Hepatocyte growth factor is a synergistic factor for the growth of hematopoietic progenitor cells
15. Hepatocyte growth factor prevents liver cirrhosis caused by dimethyl-nitrosamine in rats
16. Repopulation of host lymphohematopoietic system by donor cells during graft-versus-host reaction in unirradiated adult F1 mice injected with parental lymphocytes
17. In vivo transfection of cis element "decoy" against nuclear factor-κB binding site prevents myocardial infarction
18. Hepatocyte growth factor gene therapy of liver cirrhosis in rats
19. Identification of programmed cell death in situ via specific labelling of nuclear DNA fragmentation
20. +αβT cells with intermediate TCR induced in the liver of mice by IL-12
21. The many faces of hepatocyte growth factor: From hepatopoiesis to hematopoiesis
22. Involvement of OX40-OX40L interactions in the intestinal manifestations of murine acute graft-versus-host disease
23. A coded histologic study of hepatic graft-versus-host disease after human bone marrow transplantation
24. Differential effects of anti-Fas ligand and antitumor necrosis factor-α antibodies on acute graft-versus-host disease pathologies
25. Interleukin-12
26. Macrophage priming and lipopolysaccharide-triggered release of tumor necrosis factor alpha during graft-versus-host disease
27. Neutralizing IL-12 during induction of murine acute graft-versus-host disease polarizes the cytokine profile toward a Th2-type alloimmune response and confers long-term protection from disease
28. Interleukin-12 is required for the T-lymphocyte-independent induction of interferon-γ by an intracellular parasite and induces resistance in T-cell-deficient hosts
29. The p55 TNF-α receptor plays a critical role in T cell alloreactivity
30. Effect of graft-versus-host disease on hematopoiesis after bone marrow transplantation in mice
31. Presence of hematopoietic stem cells in the adult liver
32. CD4(+) T cells tolerized ex vivo to host alloantigen by anti-CD40 ligand (CD40L:CD154) antibody lose their graft-versus-host disease lethality capacity but retain nominal antigen responses
33. Interleukin-11 promotes T cell polarization and prevents acute graft-versus-host disease after allogeneic bone marrow transplantation
34. Keratinocyte growth factor separates graft-versus-leukemia effects from graft-versus-host disease
35. Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor