Imaging haematopoietic cells recruitment to an acute wound in vivo identifies a role for c-Met signalling

Journal of Microscopy

Volumn 250, Issue 3, 2013, Pages 200-209

  Falenta, K ^a   Rodaway, A ^a   Jones, G E ^b   Wells, C M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Inhibitors; Migration; Signalling; Wound

Indexed keywords

AMINO ACIDS; CELL SIGNALING; CELLS; CYTOLOGY; ENZYMES; IMMUNE SYSTEM; SIGNALING;

HEMATOPOIETIC CELL; IMMUNE CELLS; IMMUNE RESPONSE; IN-VIVO; INHIBITOR; MIGRATION; SIGNALING; WOUND; WOUND SITE; ZEBRAFISH EMBRYOS;

ASSAYS;

2 (3 CHLORO 4 HYDROXYANILINO) 3 (2 NITROPHENYL)MALEIMIDE; K 252A; N (3 CHLOROPHENYL) 3 [3,5 DIMETHYL 4 (4 METHYL 1 PIPERAZINYLCARBONYL) 1H PYRROL 2 YLMETHYLENE] 2,3 DIHYDRO N METHYL 2 OXO 1H INDOLE 5 SULFONAMIDE; PHOSPHOTRANSFERASE; SCATTER FACTOR RECEPTOR; TYROSINE KINASE RECEPTOR;

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE RELEASE; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; HEMATOPOIETIC CELL; IMAGING SYSTEM; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; IN VIVO STUDY; INFLAMMATION; MICROSCOPY; NEUTROPHIL; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCREENING TEST; SIGNAL TRANSDUCTION; WOUND; ZEBRA FISH;

EID: 84877665014     PISSN: 00222720     EISSN: 13652818     Source Type: Journal    
DOI: 10.1111/jmi.12035     Document Type: Article

References (47)

1. Ahmed, T., Shea, K., Masters, J.R., Jones, G.E. & Wells, C.M. (2008) A PAK4-LIMK1 pathway drives prostate cancer cell migration downstream of HGF. Cell. Signal. 20, 1320-1328.
2. Allen, W.E., Zicha, D., Ridley, A.J. & Jones, G.E. (1998) A role for Cdc42 in macrophage chemotaxis. J. Cell Biol. 141, 1147-1157.
3. Antoniades, H.N. (1991) PDGF: a multifunctional growth factor. Baillieres Clin. Endocrinol. Metab. 5, 595-613.
4. Beilmann, M., Odenthal, M., Jung, W., Vande Woude, G.F., Dienes, H.P. & Schirmacher, P. (1997) Neoexpression of the c-met/hepatocyte growth factor-scatter factor receptor gene in activated monocytes. Blood 90, 4450-4458.
5. Birchmeier, C., Birchmeier, W., Gherardi, E. & Vande Woude, G.F. (2003) Met, metastasis, motility and more. Nat. Rev. Mol. Cell Biol. 4, 915-925.
6. Bladt, F., Riethmacher, D., Isenmann, S., Aguzzi, A. & Birchmeier, C. (1995) Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud. Nature 376, 768-771.
7. Brown, S.B., Tucker, C.S., Ford, C., Lee, Y., Dunbar, D.R. & Mullins, J.J. (2007) Class III antiarrhythmic methanesulfonanilides inhibit leukocyte recruitment in zebrafish. J. Leukocyte Biol. 82, 79-84.
8. Comoglio, P.M. & Trusolino, L. (2002) Invasive growth: from development to metastasis. J. Clin. Invest. 109, 857-862.
9. Cowin, A.J., Kallincos, N., Hatzirodos, N., Robertson, J.G., Pickering, K.J., Couper, J. & Belford, D.A. (2001) Hepatocyte growth factor and macrophage-stimulating protein are upregulated during excisional wound repair in rats. Cell Tissue Res. 306, 239-250.
10. Galimi, F., Brizzi, M.F. & Comoglio, P.M. (1993) The hepatocyte growth factor and its receptor. Stem Cells 11 (Suppl 2), 22-30.
11. Galimi, F., Cottone, E., Vigna, E., Arena, N., Boccaccio, C., Giordano, S., Naldini, L. & Comoglio, P.M. (2001) Hepatocyte growth factor is a regulator of monocyte-macrophage function. J. Immunol. 166, 1241-1247.
12. Haines, L., Neyt, C., Gautier, P., Keenan, D.G., Bryson-Richardson, R.J., Hollway, G.E., Cole, N.J. & Currie, P.D. (2004) Met and Hgf signaling controls hypaxial muscle and lateral line development in the zebrafish. Development 131, 4857-4869.
13. Hall, C., Flores, M.V., Storm, T., Crosier, K. & Crosier, P. (2007) The zebrafish lysozyme C promoter drives myeloid-specific expression in transgenic fish. BMC Dev. Biol. 7, 42.
14. Huh, C.G., Factor, V.M., Sanchez, A., Uchida, K., Conner, E.A. & Thorgeirsson, S.S. (2004) Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair. Proc. Natl. Acad. Sci. USA 101, 4477-4482.
15. Kari, G., Rodeck, U. & Dicker, A.P. (2007) Zebrafish: an emerging model system for human disease and drug discovery. Clin. Pharmacol. Ther. 82, 70-80.
16. Kermorgant, S. & Parker, P.J. (2005) c-Met signalling: spatio-temporal decisions. Cell Cycle 4, 352-355.
17. Kermorgant, S., Zicha, D. & Parker, P.J. (2004) PKC controls HGF-dependent c-Met traffic, signalling and cell migration. EMBO J. 23, 3721-3734.
18. Kimmel, C.B., Ballard, W.W., Kimmel, S.R., Ullmann, B. & Schilling, T.F. (1995) Stages of embryonic development of the zebrafish. Developmental Dynamics: An Official Publication of the American Association of Anatomists 203, 253-310.
19. Kobayashi, Y. (2008) The role of chemokines in neutrophil biology. Frontiers in Bioscience: A Journal and Virtual Library 13, 2400-2407.
20. Latimer, A.J. & Jessen, J.R. (2008) Hgf/c-met expression and functional analysis during zebrafish embryogenesis. Developmental Dynamics: An Official Publication of the American Association of Anatomists 237, 3904-3915.
21. Loynes, C.A., Martin, J.S., Robertson, A., Trushell, D.M., Ingham, P.W., Whyte, M.K. & Renshaw, S.A. (2010) Pivotal advance: pharmacological manipulation of inflammation resolution during spontaneously resolving tissue neutrophilia in the zebrafish. J. Leukocyte Biol. 87, 203-212.
22. Ma, P.C., Maulik, G., Christensen, J. & Salgia, R. (2003) c-Met: structure, functions and potential for therapeutic inhibition. Cancer Metastasis Rev. 22, 309-325.
23. Ma, P.C., Jagadeeswaran, R., Jagadeesh, S. et al. (2005) Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer. Cancer Res. 65, 1479-1488.
24. Ma, P.C., Tretiakova, M.S., Nallasura, V., Jagadeeswaran, R., Husain, A.N. & Salgia, R. (2007) Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion. Brit. J. Cancer 97, 368-377.
25. Mathias, J.R., Dodd, M.E., Walters, K.B., Rhodes, J., Kanki, J.P., Look, A.T. & Huttenlocher, A. (2007) Live imaging of chronic inflammation caused by mutation of zebrafish Hai1. J. Cell Sci. 120, 3372-3383.
26. Matsumoto, K. & Nakamura, T. (2001) Hepatocyte growth factor: renotropic role and potential therapeutics for renal diseases. Kidney Int. 59, 2023-2038.
27. Moransard, M., Sawitzky, M., Fontana, A. & Suter, T. (2010) Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis. Glia 58, 559-571.
28. Niethammer, P., Grabher, C., Look, A.T. & Mitchison, T.J. (2009) A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish. Nature 459, 996-999.
29. Redd, M.J., Kelly, G., Dunn, G., Way, M. & Martin, P. (2006) Imaging macrophage chemotaxis in vivo: studies of microtubule function in zebrafish wound inflammation. Cell Motil. Cytoskel. 63, 415-422.
30. Renshaw, S.A., Loynes, C.A., Trushell, D.M., Elworthy, S., Ingham, P.W. & Whyte, M.K. (2006) A transgenic zebrafish model of neutrophilic inflammation. Blood 108, 3976-3978.
31. Ridley, A.J. (2001) Rho family proteins: coordinating cell responses. Trends Cell. Biol. 11, 471-477.
32. Rosse, C., Linch, M., Kermorgant, S., Cameron, A.J., Boeckeler, K. & Parker, P.J. (2010) PKC and the control of localized signal dynamics. Nat. Rev. Mol. Cell Biol. 11, 103-112.
33. Royal, I., Lamarche-Vane, N., Lamorte, L., Kaibuchi, K. & Park, M. (2000) Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation. Mol. Biol. Cell 11, 1709-1725.
34. Sattler, M. & Salgia, R. (2007) c-Met and hepatocyte growth factor: potential as novel targets in cancer therapy. Cur. Oncol. Rep. 9, 102-108.
35. Schmidt, C., Bladt, F., Goedecke, S., Brinkmann, V., Zschiesche, W., Sharpe, M., Gherardi, E. & Birchmeier, C. (1995) Scatter factor/hepatocyte growth factor is essential for liver development. Nature 373, 699-702.
36. Sheehan, H.L. & Storey, G.W. (1947) An improved method of staining leucocyte granules with Sudan black B. J. Pathol. Bacteriol. 59, 336-337.
37. Skibinski, G. (2003) The role of hepatocyte growth factor/c-met interactions in the immune system. Archivum Immunologiae et Therapiae Experimentalis 51, 277-282.
38. Skibinski, G., Skibinska, A. & James, K. (2001) The role of hepatocyte growth factor and its receptor c-met in interactions between lymphocytes and stromal cells in secondary human lymphoid organs. Immunology 102, 506-514.
39. Soehnlein, O. & Lindbom, L. (2010) Phagocyte partnership during the onset and resolution of inflammation. Nat. Rev. Immunol. 10, 427-439.
40. Stockton, R.A., Schaefer, E. & Schwartz, M.A. (2004) p21-activated kinase regulates endothelial permeability through modulation of contractility. J. Biol. Chem. 279, 46621-46630.
41. Tinsley, J.H., Hunter, F.A. & Childs, E.W. (2009) PKC and MLCK-dependent, cytokine-induced rat coronary endothelial dysfunction. J. Surg. Res. 152, 76-83.
42. Uehara, Y., Minowa, O., Mori, C., Shiota, K., Kuno, J., Noda, T. & Kitamura, N. (1995) Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor. Nature 373, 702-705.
43. Wang, X., Le, P., Liang, C. et al. (2003) Potent and selective inhibitors of the Met [hepatocyte growth factor/scatter factor (HGF/SF) receptor] tyrosine kinase block HGF/SF-induced tumor cell growth and invasion. Mol. Cancer Ther. 2, 1085-1092.
44. Wells, C.M., Abo, A. & Ridley, A.J. (2002) PAK4 is activated via PI3K in HGF-stimulated epithelial cells. J. Cell Sci. 115, 3947-3956.
45. Wells, C.M., Ahmed, T., Masters, J.R. & Jones, G.E. (2005) Rho family GTPases are activated during HGF-stimulated prostate cancer-cell scattering. Cell Motil. Cytoskel. 62, 180-194.
46. Westerfield, M. (1993) The Zebrafish Book: A Guide for the Laboratory Use of Zebrafish (Brachydanio Rerio). University of Oregon Press, Eugene, OR.
47. Zhang, Y., Bai, X.T., Zhu, K.Y. et al. (2008) In vivo interstitial migration of primitive macrophages mediated by JNK-matrix metalloproteinase 13 signaling in response to acute injury. J. Immunol. 181, 2155-2164.