Obestatin promotes proliferation and survival of adult hippocampal progenitors and reduces amyloid-β-induced toxicity

Molecular and Cellular Endocrinology

Volumn 422, Issue , 2016, Pages 18-30

  Gargantini, Eleonora ^a,b   Lazzari, Laura ^a,b   Settanni, Fabio ^a,b   Taliano, Marina ^a,b   Trovato, Letizia ^a,b   Gesmundo, Iacopo ^a,b   Ghigo, Ezio ^b   Granata, Riccarda ^a,b  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

Amyloid beta peptide; Cell survival; GSK 3 catenin; Hippocampal progenitors; Obestatin; PI3K Akt

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; BETA CATENIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OBESTATIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TAU PROTEIN; EXENDIN 4; MAPT PROTEIN, RAT; OBESTATIN, RAT; PEPTIDE; PEPTIDE HORMONE; VENOM;

ADULT; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HIPPOCAMPUS; IMMUNOREACTIVITY; INTRACELLULAR SIGNALING; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RAT; STEM CELL; ADULT STEM CELL; ANIMAL; CYTOLOGY; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ADULT STEM CELLS; AMYLOID BETA-PEPTIDES; ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; HIPPOCAMPUS; PEPTIDE HORMONES; PEPTIDES; PHOSPHORYLATION; RATS; SIGNAL TRANSDUCTION; TAU PROTEINS; VENOMS;

EID: 84961357803     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2015.11.008     Document Type: Article

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