Glycolytic metabolite methylglyoxal inhibits cold and menthol activation of the transient receptor potential melastatin type 8 channel

Journal of Neuroscience Research

Volumn 94, Issue 3, 2016, Pages 282-294

  Ciobanu, A C ^a,b   Selescu, T ^a   Gasler, I ^a,c   Soltuzu, L ^a,d   Babes, A ^a  

^a UNIVERSITY OF BUCHAREST   (Romania)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^c UNIVERSITY OF BASEL   (Switzerland)

^d SISSA   (Italy)

Author keywords

Dorsal root ganglion; Pain; Sensory; Thermoreception; TRP channel

Indexed keywords

ALLYL ISOTHIOCYANATE; CAPSAICIN; MENTHOL; MESSENGER RNA; METHYLGLYOXAL; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; ANTIPRURITIC AGENT; CALCIUM; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM8 PROTEIN, HUMAN;

ADULT; ALLODYNIA; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; CELL POPULATION; CLINICAL ASSESSMENT; COLD SENSITIVITY; CONTROLLED STUDY; COOLING; DIABETIC NEUROPATHY; DIABETIC PATIENT; GLYCOLYSIS; HUMAN; LONG TERM CARE; LONG TERM EXPOSURE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL GANGLION; ANIMAL; CELL CULTURE; COLD; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; INTRACELLULAR FLUID; MALE; METABOLISM; PATCH CLAMP TECHNIQUE; TIME FACTOR; WISTAR RAT;

ANIMALS; ANTIPRURITICS; CALCIUM; CELLS, CULTURED; COLD TEMPERATURE; DOSE-RESPONSE RELATIONSHIP, DRUG; GANGLIA, SPINAL; HEK293 CELLS; HUMANS; INTRACELLULAR FLUID; MALE; MENTHOL; NEURONS; PATCH-CLAMP TECHNIQUES; PYRUVALDEHYDE; RATS; RATS, WISTAR; RNA, MESSENGER; TIME FACTORS; TRPM CATION CHANNELS;

EID: 84961350084     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.23700     Document Type: Article

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