Strategies of eradicating glioma cells: A multi-scale mathematical model with miR-451-AMPK-mTOR control

PLoS ONE

Volumn 10, Issue 1, 2015, Pages

  Kim, Yangjin ^a,b   Powathil, Gibin ^c,e   Kang, Hyunji ^a   Trucu, Dumitru ^c   Kim, Hyeongi ^a   Lawler, Sean ^d   Chaplain, Mark ^c  

^a Konkuk University   (South Korea)

^b OHIO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e SWANSEA UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; MATRIX METALLOPROTEINASE; MICRORNA; MICRORNA 451; OXYGEN; ROSCOVITINE; UNCLASSIFIED DRUG; MIRN451 MICRORNA, HUMAN; TARGET OF RAPAMYCIN KINASE;

BIOCHEMISTRY; BLOOD VESSEL; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL GROWTH; CELL INTERACTION; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GLIOBLASTOMA; GLIOMA CELL; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; MATHEMATICAL MODEL; METABOLIC STRESS; REVIEW; SIGNAL TRANSDUCTION; SURVIVAL RATE; TUMOR MICROENVIRONMENT; ALGORITHM; BIOLOGICAL MODEL; BRAIN NEOPLASMS; GENE EXPRESSION REGULATION; GENETICS; GLIOMA; METABOLISM; PATHOLOGY; TREATMENT OUTCOME; TUMOR INVASION;

ALGORITHMS; AMP-ACTIVATED PROTEIN KINASES; BRAIN NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; MICRORNAS; MODELS, BIOLOGICAL; NEOPLASM INVASIVENESS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TREATMENT OUTCOME; TUMOR MICROENVIRONMENT;

EID: 84961289886     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0114370     Document Type: Review

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