miR451 and AMPK mutual antagonism in glioma cell migration and proliferation: A mathematical model

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Kim, Yangjin ^a   Roh, Soyeon ^a   Lawler, Sean ^b   Friedman, Avner ^c  

^a UNIVERSITY OF MICHIGAN DEARBORN   (United States)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MICRORNA; MICRORNA 451; UNCLASSIFIED DRUG; MIRN451 MICRORNA, HUMAN;

ARTICLE; CANCER GROWTH; CANCER INVASION; CELL MIGRATION; DRUG TARGETING; GENETIC REGULATION; GLIOBLASTOMA; GLIOMA CELL; GLUCOSE TRANSPORT; IN VITRO STUDY; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; OSCILLATION; SIGNAL TRANSDUCTION; SIMULATION; TUMOR MICROENVIRONMENT; UPREGULATION; BIOLOGICAL MODEL; CELL MOTION; CELL PROLIFERATION; DRUG ANTAGONISM; ENZYMOLOGY; GENETICS; GLIOMA; METABOLISM; PATHOLOGY;

AMP-ACTIVATED PROTEIN KINASES; CELL MOVEMENT; CELL PROLIFERATION; GLIOMA; MICRORNAS; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 83755173769     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028293     Document Type: Article

References (24)

1. Furnari F, Fenton T, Bachoo R, Mukasa A, Stommel J, et al. (2007) Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev 21: 2683-710.
2. Godlewski J, Nowicki M, Bronisz A, Palatini GNJ, Lay MD, et al. (2010) Mircrorna-451 regulates lkb1/ampk signaling and allows adaptation to metabolic stress in glioma cells. Molecular Cell 37: 620-632.
3. Warburg O, (1956) On the origin of cancer cells. Science 123: 309-14.
4. Kim J, Dang C, (2006) Cancer's molecular sweet tooth and the warburg effect. Cancer Res 66: 8927-30.
5. Heiden M, Cantley L, Thompson C, (2009) Understanding the warburg effect: the metabolic re-quirements of cell proliferation. Science 324: 1029-33.
6. Jones R, Thompson C, (2009) Tumor suppressors and cell metabolism: a recipe for cancer growth. Genes Dev 23: 537-48.
7. Hardie D, (2007) Amp-activated/snf1 protein kinases: conserved guardians of cellular energy. Nat Rev Mol Cell Biol 8: 774-85.
8. Kim Y, Lawler S, Nowicki M, Chiocca E, Friedman A, (2009) A mathematical model of brain tumor: pattern formation of glioma cells outside the tumor spheroid core. J Theo Biol 260: 359-371.
9. Tyson R, Stern L, LeVeque R, (2000) Fractional step methods applied to a chemotaxis model. J Math Biol 41: 455-75.
10. Kim Y, Stolarska M, Othmer H, (2007) A hybrid model for tumor spheroid growth in vitro i: Theoretical development and early results. Math Models Methods in Appl Scis 17: 1773-1798.
11. Rejniak K, Anderson A, (2011) Hybrid models of tumor growth. WIRES Syst Biol Med 3: 115-125.
12. Aguda B, Kim Y, Hunter M, Friedman A, Marsh C, (2008) Microrna regulation of a cancer network: Consequences of the feedback loops involving mir-17-92, e2f, and myc. PNAS 105: 19678-19683.
13. Crute B, Seefeld K, Gamble J, Kemp B, Witters L, (1998) Functional domains of the alpha1 catalytic subunit of the amp-activated protein kinase. J Biol Chem 273: 35347-54.
14. Gantier M, McCoy C, Rusinova I, Saulep D, Wang D, et al. (2011) Analysis of microrna turnover in mammalian cells following dicer1 ablation. Nucleic Acids Res 39: 5692-703.
15. Saffarian S, Collier I, Marmer B, Elson E, Goldberg G, (2004) Interstitial collagenase is a brownian ratchet driven by proteolysis of collagen. Science 306: 108-11.
16. Sherratt JA, Murray JD, (1990) Models of epidermal wound healing. Proc R Soc Lond B241: 29-36.
17. Rong Z, Cheema U, Vadgama P, (2006) Needle enzyme electrode based glucose diffusive transport measurement in a collagen gel and validation of a simulation model. Analyst 131: 816-21.
18. Mercapide J, Cicco R, Castresana J, Klein-Szanto A, (2003) Stromelysin-1/matrixmetalloproteinase-3 (mmp-3) expression accounts for invasive properties of human astrocy-toma cell lines. Int J Cancer 106: 676-82.
19. Sander L, Deisboeck T, (2002) Growth patterns of microscopic brain tumors. Phys Rev E 66: 051901.
20. Li C, (1982) The glucose distribution in 9l rat brain multicell tumor spheroids and its effect on cell necrosis. Cancer 50: 2066-73.
21. Kaufman L, Brangwynne C, Kasza K, Filippidi E, Gordon V, et al. (2005) Glioma expansion in collagen i matrices: Analyzing collagen concentration-dependent growth and motility patterns. Biophys J BioFAST 89: 635-650.
22. Stein A, Demuth T, Mobley D, Berens M, Sander L, (2007) A mathematical model of glioblastoma tumor spheroid invasion in a three-dimensional in vitro experiment. Biophys J 92: 356-65.
23. Annabi B, Bouzeghrane M, Currie J, Hawkins R, Dulude H, et al. (2005) A psp94-derived peptide pck3145 inhibits mmp-9 secretion and triggers cd44 cell surface shedding: implication in tumor metastasis. Clin Exp Metastasis 22: 429-39.
24. Deisboeck T, Berens M, Kansal A, Torquato S, Stemmer-Rachamimov A, et al. (2001) Pattern of self-organization in tumour systems: complex growth dynamics in a novel brain tumour spheroid model. Cell Prolif 34: 115-134.