-
1
-
-
0021775497
-
Double asymmetric synthesis and a new strategy for stereochemical control in organic synthesis
-
Masamune, S., Choy, W., Petersen, J. S., Sita, L. R. Double asymmetric synthesis and a new strategy for stereochemical control in organic synthesis. Angew. Chem. Int. Ed. Engl. 24, 1-30 (1985).
-
(1985)
Angew. Chem. Int. Ed. Engl
, vol.24
, pp. 1-30
-
-
Masamune, S.1
Choy, W.2
Petersen, J.S.3
Sita, L.R.4
-
2
-
-
84870918230
-
Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature
-
Arnison, P. G. et al. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat. Prod. Rep. 30, 108-160 (2013).
-
(2013)
Nat. Prod. Rep
, vol.30
, pp. 108-160
-
-
Arnison, P.G.1
-
3
-
-
84878560267
-
Ribosomally synthesized and posttranslationally modified peptide natural products: New insights into the role of leader and core peptides during biosynthesis
-
Yang, X., van der Donk, W. A. Ribosomally synthesized and posttranslationally modified peptide natural products: new insights into the role of leader and core peptides during biosynthesis. Chem. Eur. J. 19, 7662-7677 (2013).
-
(2013)
Chem. Eur. J
, vol.19
, pp. 7662-7677
-
-
Yang, X.1
Van Der Donk, W.A.2
-
4
-
-
0030046733
-
Comparison of lantibiotic gene clusters and encoded proteins
-
Siezen, R. J., Kuipers, O. P., de Vos, W. M. Comparison of lantibiotic gene clusters and encoded proteins. Anton. Leeuw. 69, 171-184 (1996).
-
(1996)
Anton. Leeuw
, vol.69
, pp. 171-184
-
-
Siezen, R.J.1
Kuipers, O.P.2
De Vos, W.M.3
-
5
-
-
0942268866
-
Lacticin 481: In vitro reconstitution of lantibiotic synthetase activity
-
Xie, L. et al. Lacticin 481: in vitro reconstitution of lantibiotic synthetase activity. Science 303, 679-681 (2004).
-
(2004)
Science
, vol.303
, pp. 679-681
-
-
Xie, L.1
-
6
-
-
65949089371
-
Lantibiotics: Mode of action, biosynthesis and bioengineering
-
Bierbaum, G., Sahl, H. G. Lantibiotics: mode of action, biosynthesis and bioengineering. Curr. Pharm. Biotechnol. 10, 2-18 (2009).
-
(2009)
Curr. Pharm. Biotechnol
, vol.10
, pp. 2-18
-
-
Bierbaum, G.1
Sahl, H.G.2
-
7
-
-
13844314218
-
Bacterial lantibiotics: Strategies to improve therapeutic potential
-
Cotter, P. D., Hill, C., Ross, R. P. Bacterial lantibiotics: strategies to improve therapeutic potential. Curr. Protein Pept. Sci. 6, 61-75 (2005).
-
(2005)
Curr. Protein Pept. Sci
, vol.6
, pp. 61-75
-
-
Cotter, P.D.1
Hill, C.2
Ross, R.P.3
-
8
-
-
14844340728
-
Biosynthesis and mode of action of lantibiotics
-
Chatterjee, C., Paul, M., Xie, L., van der Donk, W. A. Biosynthesis and mode of action of lantibiotics. Chem. Rev. 105, 633-684 (2005).
-
(2005)
Chem. Rev
, vol.105
, pp. 633-684
-
-
Chatterjee, C.1
Paul, M.2
Xie, L.3
Van Der Donk, W.A.4
-
9
-
-
84874115767
-
The sequence of the enterococcal cytolysin imparts unusual lanthionine stereochemistry
-
Tang, W., van der Donk, W. A. The sequence of the enterococcal cytolysin imparts unusual lanthionine stereochemistry. Nature Chem. Biol. 9, 157-159 (2013).
-
(2013)
Nature Chem. Biol
, vol.9
, pp. 157-159
-
-
Tang, W.1
Van Der Donk, W.A.2
-
10
-
-
13844316746
-
Enterococcal cytolysin: A novel two component peptide system that serves as a bacterial defense against eukaryotic and prokaryotic cells
-
Cox, C. R., Coburn, P. S., Gilmore, M. S. Enterococcal cytolysin: a novel two component peptide system that serves as a bacterial defense against eukaryotic and prokaryotic cells. Curr. Protein Pept. Sci. 6, 77-84 (2005).
-
(2005)
Curr. Protein Pept. Sci
, vol.6
, pp. 77-84
-
-
Cox, C.R.1
Coburn, P.S.2
Gilmore, M.S.3
-
11
-
-
0025985759
-
Bacteremia caused by hemolytic, high-level gentamicin-resistant Enterococcus faecalis
-
Huycke, M. M., Spiegel, C. A., Gilmore, M. S. Bacteremia caused by hemolytic, high-level gentamicin-resistant Enterococcus faecalis. Antimicrob. Agents Chemother. 35, 1626-1634 (1991).
-
(1991)
Antimicrob. Agents Chemother
, vol.35
, pp. 1626-1634
-
-
Huycke, M.M.1
Spiegel, C.A.2
Gilmore, M.S.3
-
12
-
-
0026569555
-
The hemolysin/bacteriocin produced by enterococci is a marker of pathogenicity
-
Libertin, C. R., Dumitru, R., Stein, D. S. The hemolysin/bacteriocin produced by enterococci is a marker of pathogenicity. Diagn. Microbiol. Infect. Dis. 15, 115-120 (1992).
-
(1992)
Diagn. Microbiol. Infect. Dis
, vol.15
, pp. 115-120
-
-
Libertin, C.R.1
Dumitru, R.2
Stein, D.S.3
-
13
-
-
0027367211
-
Plasmid-associated hemolysin and aggregation substance production contribute to virulence in experimental enterococcal endocarditis
-
Chow, J. W. et al. Plasmid-associated hemolysin and aggregation substance production contribute to virulence in experimental enterococcal endocarditis. Antimicrob. Agents Chemother. 37, 2474-2477 (1993).
-
(1993)
Antimicrob. Agents Chemother
, vol.37
, pp. 2474-2477
-
-
Chow, J.W.1
-
14
-
-
33751204753
-
Discovery and in vitro biosynthesis of haloduracin, a twocomponent lantibiotic
-
McClerren, A. L. et al. Discovery and in vitro biosynthesis of haloduracin, a twocomponent lantibiotic. Proc. Natl Acad. Sci. USA 103, 17243-17248 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 17243-17248
-
-
McClerren, A.L.1
-
15
-
-
79952253258
-
Production of lantipeptides in Escherichia coli
-
Shi, Y., Yang, X., Garg, N., van der Donk, W. A. Production of lantipeptides in Escherichia coli. J. Am. Chem. Soc. 133, 2338-2341 (2011).
-
(2011)
J. Am. Chem. Soc
, vol.133
, pp. 2338-2341
-
-
Shi, Y.1
Yang, X.2
Garg, N.3
Van Der Donk, W.A.4
-
16
-
-
80052580657
-
Solid supported chemical syntheses of both components of the lantibiotic lacticin 3147
-
Liu, W., Chan, A. S., Liu, H., Cochrane, S. A., Vederas, J. C. Solid supported chemical syntheses of both components of the lantibiotic lacticin 3147. J. Am. Chem. Soc. 133, 14216-14219 (2011).
-
(2011)
J. Am. Chem. Soc
, vol.133
, pp. 14216-14219
-
-
Liu, W.1
Chan, A.S.2
Liu, H.3
Cochrane, S.A.4
Vederas, J.C.5
-
17
-
-
84862578924
-
Lacticin 3147-biosyn thesis, molecular analysis, immunity, bioengineering and applications
-
Suda, S., Cotter, P. D., Hill, C., Ross, R. P. Lacticin 3147-biosynthesis, molecular analysis, immunity, bioengineering and applications. Curr. Protein Pept. Sci. 13, 193-204 (2012).
-
(2012)
Curr. Protein Pept. Sci
, vol.13
, pp. 193-204
-
-
Suda, S.1
Cotter, P.D.2
Hill, C.3
Ross, R.P.4
-
18
-
-
77953742146
-
Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria
-
Li, B. et al. Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria. Proc. Natl Acad. Sci. USA 107, 10430-10435 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 10430-10435
-
-
Li, B.1
-
19
-
-
84861624891
-
Structural characterization of four prochlorosins: A novel class of lantipeptides produced by planktonic marine cyanobacteria
-
Tang, W., van der Donk, W. A. Structural characterization of four prochlorosins: a novel class of lantipeptides produced by planktonic marine cyanobacteria. Biochemistry 51, 4271-4279 (2012).
-
(2012)
Biochemistry
, vol.51
, pp. 4271-4279
-
-
Tang, W.1
Van Der Donk, W.A.2
-
20
-
-
84868578132
-
Evolution of lanthipeptide synthetases
-
Zhang, Q., Yu, Y., Velásquez, J. E., van der Donk, W. A. Evolution of lanthipeptide synthetases. Proc. Natl Acad. Sci. USA 109, 18361-18366 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 18361-18366
-
-
Zhang, Q.1
Yu, Y.2
Velásquez, J.E.3
Van Der Donk, W.A.4
-
21
-
-
84880367346
-
A general method for fluorescent labeling of the N-termini of lanthipeptides and its application to visualize their cellular localization
-
Bindman, N. A., van der Donk, W. A. A general method for fluorescent labeling of the N-termini of lanthipeptides and its application to visualize their cellular localization. J. Am. Chem. Soc. 135, 10362-10371 (2013).
-
(2013)
J. Am. Chem. Soc
, vol.135
, pp. 10362-10371
-
-
Bindman, N.A.1
Van Der Donk, W.A.2
-
22
-
-
84870655088
-
Gas-phase studies of substrates for the DNA mismatch repair enzyme MutY
-
Michelson, A. Z. et al. Gas-phase studies of substrates for the DNA mismatch repair enzyme MutY. J. Am. Chem. Soc. 134, 19839-19850 (2012).
-
(2012)
J. Am. Chem. Soc
, vol.134
, pp. 19839-19850
-
-
Michelson, A.Z.1
-
23
-
-
84863931099
-
Effect of isotopically sensitive branching on product distribution for pentalenene synthase: Support for a mechanism predicted by quantum chemistry
-
Zu, L. et al. Effect of isotopically sensitive branching on product distribution for pentalenene synthase: support for a mechanism predicted by quantum chemistry. J. Am. Chem. Soc. 134, 11369-11371 (2012).
-
(2012)
J. Am. Chem. Soc
, vol.134
, pp. 11369-11371
-
-
Zu, L.1
-
24
-
-
0037008401
-
The conformation of dehydroalanine in short homopeptides: Molecular dynamics simulations of a 6-residue chain
-
Zanuy, D., Casanovas, J., Alemán, C. The conformation of dehydroalanine in short homopeptides: molecular dynamics simulations of a 6-residue chain. Biophys. Chem. 98, 301-312 (2002).
-
(2002)
Biophys. Chem
, vol.98
, pp. 301-312
-
-
Zanuy, D.1
Casanovas, J.2
Alemán, C.3
-
25
-
-
1942531292
-
Peptide design using alpha, betadehydro amino acids: From beta-turns to helical hairpins
-
Mathur, P., Ramakumar, S., Chauhan, V. S. Peptide design using alpha, betadehydro amino acids: from beta-turns to helical hairpins. Biopolymers 76, 150-161 (2004).
-
(2004)
Biopolymers
, vol.76
, pp. 150-161
-
-
Mathur, P.1
Ramakumar, S.2
Chauhan, V.S.3
-
26
-
-
79958862780
-
Transition states and energetics of nucleophilic additions of thiols to substituted alpha, betaunsaturated ketones: Substituent effects involve enone stabilization, product branching, and solvation
-
Krenske, E. H., Petter, R. C., Zhu, Z., Houk, K. N. Transition states and energetics of nucleophilic additions of thiols to substituted alpha, betaunsaturated ketones: substituent effects involve enone stabilization, product branching, and solvation. J. Org. Chem. 76, 5074-5081 (2011).
-
(2011)
J. Org. Chem
, vol.76
, pp. 5074-5081
-
-
Krenske, E.H.1
Petter, R.C.2
Zhu, Z.3
Houk, K.N.4
-
27
-
-
84908033373
-
Structure and biosynthesis of carnolysin, a homologue of enterococcal cytolysin with D-amino acids
-
Lohans, C. T., Li, J. L., Vederas, J. C. Structure and biosynthesis of carnolysin, a homologue of enterococcal cytolysin with D-amino acids. J. Am. Chem. Soc. 136, 13150-13153 (2014).
-
(2014)
J. Am. Chem. Soc
, vol.136
, pp. 13150-13153
-
-
Lohans, C.T.1
Li, J.L.2
Vederas, J.C.3
-
28
-
-
84862777743
-
A fungal ketoreductase domain that displays substrate-dependent stereospecificity
-
Zhou, H. et al. A fungal ketoreductase domain that displays substrate-dependent stereospecificity. Nature Chem. Biol. 8, 331-333 (2012).
-
(2012)
Nature Chem. Biol
, vol.8
, pp. 331-333
-
-
Zhou, H.1
-
29
-
-
0034059496
-
Inverting enantioselectivity by directed evolution of hydantoinase for improved production of L-methionine
-
May, O., Nguyen, P. T., Arnold, F. H. Inverting enantioselectivity by directed evolution of hydantoinase for improved production of L-methionine. Nature Biotechnol. 18, 317-320 (2000).
-
(2000)
Nature Biotechnol
, vol.18
, pp. 317-320
-
-
May, O.1
Nguyen, P.T.2
Arnold, F.H.3
-
30
-
-
0041430558
-
Controlling chirality
-
Turner, N. J. Controlling chirality. Curr. Opin. Biotechnol. 14, 401-406 (2003).
-
(2003)
Curr. Opin. Biotechnol
, vol.14
, pp. 401-406
-
-
Turner, N.J.1
-
31
-
-
57349130701
-
Enantiocomplementary enzymes: Classification, molecular basis for their enantiopreference, and prospects for mirror-image biotransformations
-
Mugford, P. F., Wagner, U. G., Jiang, Y., Faber, K., Kazlauskas, R. J. Enantiocomplementary enzymes: classification, molecular basis for their enantiopreference, and prospects for mirror-image biotransformations. Angew. Chem. Int. Ed. 47, 8782-8793 (2008).
-
(2008)
Angew. Chem. Int. Ed
, vol.47
, pp. 8782-8793
-
-
Mugford, P.F.1
Wagner, U.G.2
Jiang, Y.3
Faber, K.4
Kazlauskas, R.J.5
-
32
-
-
78149432825
-
Laboratory evolution of stereoselective enzymes: A prolific source of catalysts for asymmetric reactions
-
Reetz, M. T. Laboratory evolution of stereoselective enzymes: a prolific source of catalysts for asymmetric reactions. Angew. Chem. Int. Ed. 50, 138-174 (2011).
-
(2011)
Angew. Chem. Int. Ed
, vol.50
, pp. 138-174
-
-
Reetz, M.T.1
-
33
-
-
84904895638
-
Mechanistic studies on the substratetolerant lanthipeptide synthetase ProcM
-
Mukherjee, S., van der Donk, W. A. Mechanistic studies on the substratetolerant lanthipeptide synthetase ProcM. J. Am. Chem. Soc. 136, 10450-10459 (2014).
-
(2014)
J. Am. Chem. Soc
, vol.136
, pp. 10450-10459
-
-
Mukherjee, S.1
Van Der Donk, W.A.2
-
34
-
-
2942532422
-
Development and testing of a general AMBER force field
-
Wang, J., Wolf, R. M., Caldwell, J. W., Kollman, P. A., Case, D. A. Development and testing of a general AMBER force field. J. Comput. Chem. 25, 1157-1174 (2004).
-
(2004)
J. Comput. Chem
, vol.25
, pp. 1157-1174
-
-
Wang, J.1
Wolf, R.M.2
Caldwell, J.W.3
Kollman, P.A.4
Case, D.A.5
-
35
-
-
3042524904
-
A well-behaved electrostatic potential based method using charge restraints for deriving atomic charges: The RESP model
-
Bayly, C. I., Cieplak, P., Cornell, W. D., Kollman, P. A. A well-behaved electrostatic potential based method using charge restraints for deriving atomic charges: the RESP model. J. Phys. Chem. 97, 10269-10280 (1993).
-
(1993)
J. Phys. Chem
, vol.97
, pp. 10269-10280
-
-
Bayly, C.I.1
Cieplak, P.2
Cornell, W.D.3
Kollman, P.A.4
-
36
-
-
33846823909
-
Particle mesh Ewald: An N-log(N) method for Ewald sums in large systems
-
Darden, T., York, D., Pedersen, L. Particle mesh Ewald: an N-log(N) method for Ewald sums in large systems. J. Chem. Phys. 98, 10089-10092 (1993).
-
(1993)
J. Chem. Phys
, vol.98
, pp. 10089-10092
-
-
Darden, T.1
York, D.2
Pedersen, L.3
-
37
-
-
3142716857
-
Accelerated molecular dynamics: A promising and efficient simulation method for biomolecules
-
Hamelberg, D., Mongan, J., McCammon, J. A. Accelerated molecular dynamics: a promising and efficient simulation method for biomolecules. J. Chem. Phys. 120, 11919-11929 (2004).
-
(2004)
J. Chem. Phys
, vol.120
, pp. 11919-11929
-
-
Hamelberg, D.1
Mongan, J.2
McCammon, J.A.3
-
38
-
-
84866146945
-
Routine access to millisecond time scale events with accelerated molecular dynamics
-
Pierce, L. C., Salomon-Ferrer, R., de Oliveira, C. A. F., McCammon, J. A., Walker, R. C. Routine access to millisecond time scale events with accelerated molecular dynamics. J. Chem. Theory Comput. 8, 2997-3002 (2012).
-
(2012)
J. Chem. Theory Comput
, vol.8
, pp. 2997-3002
-
-
Pierce, L.C.1
Salomon-Ferrer, R.2
De Oliveira, C.A.F.3
McCammon, J.A.4
Walker, R.C.5
-
39
-
-
70450206724
-
-
Gaussian Inc., Wallingford, Connecticut
-
Frisch, M. J. et al. Gaussian 09 (Gaussian Inc., Wallingford, Connecticut, 2009).
-
(2009)
Gaussian 09
-
-
Frisch, M.J.1
-
40
-
-
55849117399
-
Long-range corrected hybrid density functionals with damped atom-atom dispersion corrections
-
Chai, J. D., Head-Gordon, M. Long-range corrected hybrid density functionals with damped atom-atom dispersion corrections. Phys. Chem. Chem. Phys. 10, 6615-6620 (2008).
-
(2008)
Phys. Chem. Chem. Phys
, vol.10
, pp. 6615-6620
-
-
Chai, J.D.1
Head-Gordon, M.2
-
41
-
-
43049141516
-
The M06 suite of density functionals for main group thermochemistry, thermochemical kinetics, noncovalent interactions, excited states, and transition elements: Two new functionals and systematic testing of four M06-class functionals and 12 other functionals
-
Zhao, Y., Truhlar, D. G. The M06 suite of density functionals for main group thermochemistry, thermochemical kinetics, noncovalent interactions, excited states, and transition elements: two new functionals and systematic testing of four M06-class functionals and 12 other functionals. Theor. Chem. Acc. 120, 215-241 (2008).
-
(2008)
Theor. Chem. Acc
, vol.120
, pp. 215-241
-
-
Zhao, Y.1
Truhlar, D.G.2
-
42
-
-
84962381218
-
Continuous surface charge polarizable continuum models of solvation. I. General formalism
-
Scalmani, G., Frisch, M. J. Continuous surface charge polarizable continuum models of solvation. I. General formalism. J. Chem. Phys. 132, 114110 (2010).
-
(2010)
J. Chem. Phys
, vol.132
, pp. 114110
-
-
Scalmani, G.1
Frisch, M.J.2
-
43
-
-
84859450266
-
Lantibiotics from Geobacillus thermodenitrificans
-
Garg, N., Tang, W., Goto, Y., Nair, S. K., van der Donk, W. A. Lantibiotics from Geobacillus thermodenitrificans. Proc. Natl Acad. Sci. USA 109, 5241-5246 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 5241-5246
-
-
Garg, N.1
Tang, W.2
Goto, Y.3
Nair, S.K.4
Van Der Donk, W.A.5
|