-
1
-
-
0037841804
-
Evolution of the protein repertoire
-
Chothia C., Gough J., Vogel C., Teichmann S.A. Evolution of the protein repertoire. Science 2003, 300:1701-1703.
-
(2003)
Science
, vol.300
, pp. 1701-1703
-
-
Chothia, C.1
Gough, J.2
Vogel, C.3
Teichmann, S.A.4
-
2
-
-
84866463338
-
Versatility from protein disorder
-
Babu M.M., Kriwacki R.W., Pappu R.V. Versatility from protein disorder. Science 2012, 337:1460-1461.
-
(2012)
Science
, vol.337
, pp. 1460-1461
-
-
Babu, M.M.1
Kriwacki, R.W.2
Pappu, R.V.3
-
3
-
-
84925114160
-
Intrinsically disordered proteins in cellular signalling and regulation
-
Wright P.E., Dyson H.J. Intrinsically disordered proteins in cellular signalling and regulation. Nat Rev: Mol Cell Biol 2015, 16:18-29.
-
(2015)
Nat Rev: Mol Cell Biol
, vol.16
, pp. 18-29
-
-
Wright, P.E.1
Dyson, H.J.2
-
4
-
-
84902446851
-
Classification of intrinsically disordered regions and proteins
-
van der Lee R., Buljan M., Lang B., Weatheritt R.J., Daughdrill G.W., Dunker A.K., Fuxreiter M., Gough J., Gsponer J., Jones D.T., et al. Classification of intrinsically disordered regions and proteins. Chem Rev 2014, 114:6589-6631.
-
(2014)
Chem Rev
, vol.114
, pp. 6589-6631
-
-
van der Lee, R.1
Buljan, M.2
Lang, B.3
Weatheritt, R.J.4
Daughdrill, G.W.5
Dunker, A.K.6
Fuxreiter, M.7
Gough, J.8
Gsponer, J.9
Jones, D.T.10
-
5
-
-
0036128797
-
Natively unfolded proteins: a point where biology waits for physics
-
Uversky V.N. Natively unfolded proteins: a point where biology waits for physics. Protein Sci 2002, 11:739-756.
-
(2002)
Protein Sci
, vol.11
, pp. 739-756
-
-
Uversky, V.N.1
-
6
-
-
84878940937
-
A decade and a half of protein intrinsic disorder: biology still waits for physics
-
Uversky V.N. A decade and a half of protein intrinsic disorder: biology still waits for physics. Protein Sci 2013, 22:693-724.
-
(2013)
Protein Sci
, vol.22
, pp. 693-724
-
-
Uversky, V.N.1
-
7
-
-
0037188377
-
Intrinsic disorder and protein function
-
Dunker A.K., Brown C.J., Lawson J.D., Iakoucheva L.M., Obradović Z. Intrinsic disorder and protein function. Biochemistry 2002, 41:6573-6582.
-
(2002)
Biochemistry
, vol.41
, pp. 6573-6582
-
-
Dunker, A.K.1
Brown, C.J.2
Lawson, J.D.3
Iakoucheva, L.M.4
Obradović, Z.5
-
8
-
-
84859484529
-
Extreme C terminus of bacterial cytoskeletal protein FtsZ plays fundamental role in assembly independent of modulatory proteins
-
Buske P.J., Levin P.A. Extreme C terminus of bacterial cytoskeletal protein FtsZ plays fundamental role in assembly independent of modulatory proteins. J Biol Chem 2012, 287:10945-10957.
-
(2012)
J Biol Chem
, vol.287
, pp. 10945-10957
-
-
Buske, P.J.1
Levin, P.A.2
-
9
-
-
84880133681
-
A flexible C-terminal linker is required for proper FtsZ assembly in vitro and cytokinetic ring formation in vivo
-
Buske P.J., Levin P.A. A flexible C-terminal linker is required for proper FtsZ assembly in vitro and cytokinetic ring formation in vivo. Mol Microbiol 2013, 89:249-263.
-
(2013)
Mol Microbiol
, vol.89
, pp. 249-263
-
-
Buske, P.J.1
Levin, P.A.2
-
10
-
-
82655181911
-
Intrinsic disorder in cell signaling and gene transcription
-
Tantos A., Han K.H., Tompa P. Intrinsic disorder in cell signaling and gene transcription. Mol Cell Endocrinol 2012, 348:457-465.
-
(2012)
Mol Cell Endocrinol
, vol.348
, pp. 457-465
-
-
Tantos, A.1
Han, K.H.2
Tompa, P.3
-
11
-
-
79959846745
-
Long unfolded linkers facilitate membrane protein import through the nuclear pore complex
-
Meinema A.C., Laba J.K., Hapsari R.A., Otten R., Mulder F.A.A., Kralt A., van den Bogaart G., Lusk C.P., Poolman B., Veenhoff L.M. Long unfolded linkers facilitate membrane protein import through the nuclear pore complex. Science 2011, 333:90-93.
-
(2011)
Science
, vol.333
, pp. 90-93
-
-
Meinema, A.C.1
Laba, J.K.2
Hapsari, R.A.3
Otten, R.4
Mulder, F.A.A.5
Kralt, A.6
van den Bogaart, G.7
Lusk, C.P.8
Poolman, B.9
Veenhoff, L.M.10
-
12
-
-
84876124126
-
Quantitative analysis of membrane protein transport across the nuclear pore complex
-
Meinema A.C., Poolman B., Veenhoff L.M. Quantitative analysis of membrane protein transport across the nuclear pore complex. Traffic 2013, 14:487-501.
-
(2013)
Traffic
, vol.14
, pp. 487-501
-
-
Meinema, A.C.1
Poolman, B.2
Veenhoff, L.M.3
-
13
-
-
84879672979
-
Intrinsically disordered protein threads through the bacterial outer-membrane Porin OmpF
-
Housden N.G., Hopper J.T.S., Lukoyanova N., Rodriguez-Larrea D., Wojdyla J.A., Klein A., Kaminska R., Bayley H., Saibil H.R., Robinson C.V., et al. Intrinsically disordered protein threads through the bacterial outer-membrane Porin OmpF. Science 2013, 340:1570-1574.
-
(2013)
Science
, vol.340
, pp. 1570-1574
-
-
Housden, N.G.1
Hopper, J.T.S.2
Lukoyanova, N.3
Rodriguez-Larrea, D.4
Wojdyla, J.A.5
Klein, A.6
Kaminska, R.7
Bayley, H.8
Saibil, H.R.9
Robinson, C.V.10
-
14
-
-
84964265749
-
Stimuli-sensitive intrinsically disordered protein brushes
-
Srinivasan N., Bhagawati M., Ananthanarayanan B., Kumar S. Stimuli-sensitive intrinsically disordered protein brushes. Nat Commun 2014, 5:5145.
-
(2014)
Nat Commun
, vol.5
, pp. 5145
-
-
Srinivasan, N.1
Bhagawati, M.2
Ananthanarayanan, B.3
Kumar, S.4
-
15
-
-
84886640659
-
Intrinsic structural disorder in cytoskeletal proteins
-
Guharoy M., Szabo B., Martos S.C., Kosol S., Tompa P. Intrinsic structural disorder in cytoskeletal proteins. Cytoskeleton 2013, 70:550-571.
-
(2013)
Cytoskeleton
, vol.70
, pp. 550-571
-
-
Guharoy, M.1
Szabo, B.2
Martos, S.C.3
Kosol, S.4
Tompa, P.5
-
16
-
-
84907406045
-
Intrinsically disordered segments affect protein half-life in the cell and during evolution
-
van der Lee R., Lang B., Kruse K., Gsponer J., de Groot N.S., Huynen M.A., Matouschek A., Fuxreiter M., Babu M.M. Intrinsically disordered segments affect protein half-life in the cell and during evolution. Cell Rep 2014, 8:1832-1844.
-
(2014)
Cell Rep
, vol.8
, pp. 1832-1844
-
-
van der Lee, R.1
Lang, B.2
Kruse, K.3
Gsponer, J.4
de Groot, N.S.5
Huynen, M.A.6
Matouschek, A.7
Fuxreiter, M.8
Babu, M.M.9
-
17
-
-
57149116929
-
Tight regulation of unstructured proteins: from transcript synthesis to protein degradation
-
Gsponer J., Futschik M.E., Teichmann S.A., Babu M.M. Tight regulation of unstructured proteins: from transcript synthesis to protein degradation. Science 2008, 322:1365-1368.
-
(2008)
Science
, vol.322
, pp. 1365-1368
-
-
Gsponer, J.1
Futschik, M.E.2
Teichmann, S.A.3
Babu, M.M.4
-
18
-
-
84862992463
-
Tissue-specific splicing of disordered segments that embed binding motifs rewires protein interaction networks
-
Buljan M., Chalancon G., Eustermann S., Wagner G.P., Fuxreiter M., Bateman A., Babu M.M. Tissue-specific splicing of disordered segments that embed binding motifs rewires protein interaction networks. Mol Cell 2012, 46:871-883.
-
(2012)
Mol Cell
, vol.46
, pp. 871-883
-
-
Buljan, M.1
Chalancon, G.2
Eustermann, S.3
Wagner, G.P.4
Fuxreiter, M.5
Bateman, A.6
Babu, M.M.7
-
19
-
-
79952959945
-
Intrinsic disorder mediates the diverse regulatory functions of the Cdk inhibitor p21
-
Wang Y.F., Fisher J.C., Mathew R., Ou L., Otieno S., Sublet J., Xiao L.M., Chen J.H., Roussel M.F., Kriwacki R.W. Intrinsic disorder mediates the diverse regulatory functions of the Cdk inhibitor p21. Nat Chem Biol 2011, 7:214-221.
-
(2011)
Nat Chem Biol
, vol.7
, pp. 214-221
-
-
Wang, Y.F.1
Fisher, J.C.2
Mathew, R.3
Ou, L.4
Otieno, S.5
Sublet, J.6
Xiao, L.M.7
Chen, J.H.8
Roussel, M.F.9
Kriwacki, R.W.10
-
20
-
-
84870835154
-
Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy
-
Borgia A., Wensley B.G., Soranno A., Nettels D., Borgia M.B., Hoffmann A., Pfeil S.H., Lipman E.A., Clarke J., Schuler B. Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy. Nat Commun 2012, 3:1195.
-
(2012)
Nat Commun
, vol.3
, pp. 1195
-
-
Borgia, A.1
Wensley, B.G.2
Soranno, A.3
Nettels, D.4
Borgia, M.B.5
Hoffmann, A.6
Pfeil, S.H.7
Lipman, E.A.8
Clarke, J.9
Schuler, B.10
-
21
-
-
84867048390
-
Polymer scaling laws of unfolded and intrinsically disordered proteins quantified with single-molecule spectroscopy
-
Hofmann H., Soranno A., Borgia A., Gast K., Nettels D., Schuler B. Polymer scaling laws of unfolded and intrinsically disordered proteins quantified with single-molecule spectroscopy. Proc Natl Acad Sci USA 2012, 109:16155-16160.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 16155-16160
-
-
Hofmann, H.1
Soranno, A.2
Borgia, A.3
Gast, K.4
Nettels, D.5
Schuler, B.6
-
22
-
-
77957092799
-
Charge interactions can dominate the dimensions of intrinsically disordered proteins
-
Mueller-Spaeth S., Soranno A., Hirschfeld V., Hofmann H., Rueegger S., Reymond L., Nettels D., Schuler B. Charge interactions can dominate the dimensions of intrinsically disordered proteins. Proc Natl Acad Sci USA 2010, 107:14609-14614.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14609-14614
-
-
Mueller-Spaeth, S.1
Soranno, A.2
Hirschfeld, V.3
Hofmann, H.4
Rueegger, S.5
Reymond, L.6
Nettels, D.7
Schuler, B.8
-
23
-
-
84897513201
-
Single-molecule spectroscopy reveals polymer effects of disordered proteins in crowded environments
-
Soranno A., Koenig I., Borgia M.B., Hofmann H., Zosel F., Nettels D., Schuler B. Single-molecule spectroscopy reveals polymer effects of disordered proteins in crowded environments. Proc Natl Acad Sci USA 2014, 111:4874-4879.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 4874-4879
-
-
Soranno, A.1
Koenig, I.2
Borgia, M.B.3
Hofmann, H.4
Zosel, F.5
Nettels, D.6
Schuler, B.7
-
24
-
-
84898039764
-
Temperature-dependent solvation modulates the dimensions of disordered proteins
-
Wuttke R., Hofmann H., Nettels D., Borgia M.B., Mittal J., Best R.B., Schuler B. Temperature-dependent solvation modulates the dimensions of disordered proteins. Proc Natl Acad Sci USA 2014, 111:5213-5218.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 5213-5218
-
-
Wuttke, R.1
Hofmann, H.2
Nettels, D.3
Borgia, M.B.4
Mittal, J.5
Best, R.B.6
Schuler, B.7
-
25
-
-
84884282981
-
Mapping protein conformational energy landscapes using NMR and molecular simulation
-
Guerry P., Mollica L., Blackledge M. Mapping protein conformational energy landscapes using NMR and molecular simulation. Chemphyschem 2013, 14:3046-3058.
-
(2013)
Chemphyschem
, vol.14
, pp. 3046-3058
-
-
Guerry, P.1
Mollica, L.2
Blackledge, M.3
-
26
-
-
84899054430
-
Testing the validity of ensemble descriptions of intrinsically disordered proteins
-
Jensen M.R., Blackledge M. Testing the validity of ensemble descriptions of intrinsically disordered proteins. Proc Natl Acad Sci USA 2014, 111:E1557-E1558.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. E1557-E1558
-
-
Jensen, M.R.1
Blackledge, M.2
-
27
-
-
84879177976
-
Describing intrinsically disordered proteins at atomic resolution by NMR
-
Jensen M.R., Ruigrok R.W.H., Blackledge M. Describing intrinsically disordered proteins at atomic resolution by NMR. Curr Opin Struct Biol 2013, 23:426-435.
-
(2013)
Curr Opin Struct Biol
, vol.23
, pp. 426-435
-
-
Jensen, M.R.1
Ruigrok, R.W.H.2
Blackledge, M.3
-
28
-
-
84866403844
-
Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution
-
Ozenne V., Schneider R., Yao M., Huang J.-R., Salmon L., Zweckstetter M., Jensen M.R., Blackledge M. Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution. J Am Chem Soc 2012, 134:15138-15148.
-
(2012)
J Am Chem Soc
, vol.134
, pp. 15138-15148
-
-
Ozenne, V.1
Schneider, R.2
Yao, M.3
Huang, J.-R.4
Salmon, L.5
Zweckstetter, M.6
Jensen, M.R.7
Blackledge, M.8
-
29
-
-
84912550722
-
Long-range correlated dynamics in intrinsically disordered proteins
-
Parigi G., Rezaei-Ghaleh N., Giachetti A., Becker S., Fernandez C., Blackledge M., Griesinger C., Zweckstetter M., Luchinat C. Long-range correlated dynamics in intrinsically disordered proteins. J Am Chem Soc 2014, 136:16201-16209.
-
(2014)
J Am Chem Soc
, vol.136
, pp. 16201-16209
-
-
Parigi, G.1
Rezaei-Ghaleh, N.2
Giachetti, A.3
Becker, S.4
Fernandez, C.5
Blackledge, M.6
Griesinger, C.7
Zweckstetter, M.8
Luchinat, C.9
-
30
-
-
84893557613
-
Predictive atomic resolution descriptions of intrinsically disordered hTau40 and alpha-synuclein in solution from NMR and small angle scattering
-
Schwalbe M., Ozenne V., Bibow S., Jaremko M., Jaremko L., Gajda M., Jensen M.R., Biernat J., Becker S., Mandelkow E., et al. Predictive atomic resolution descriptions of intrinsically disordered hTau40 and alpha-synuclein in solution from NMR and small angle scattering. Structure 2014, 22:238-249.
-
(2014)
Structure
, vol.22
, pp. 238-249
-
-
Schwalbe, M.1
Ozenne, V.2
Bibow, S.3
Jaremko, M.4
Jaremko, L.5
Gajda, M.6
Jensen, M.R.7
Biernat, J.8
Becker, S.9
Mandelkow, E.10
-
31
-
-
80053368232
-
Chain collapse of an amyloidogenic intrinsically disordered protein
-
Jain N., Bhattacharya M., Mukhopadhyay S. Chain collapse of an amyloidogenic intrinsically disordered protein. Biophys J 2011, 101:1720-1729.
-
(2011)
Biophys J
, vol.101
, pp. 1720-1729
-
-
Jain, N.1
Bhattacharya, M.2
Mukhopadhyay, S.3
-
32
-
-
84883471917
-
From sequence and forces to structure function, and evolution of intrinsically disordered proteins
-
Forman-Kay J.D., Mittag T. From sequence and forces to structure function, and evolution of intrinsically disordered proteins. Structure 2013, 21:1492-1499.
-
(2013)
Structure
, vol.21
, pp. 1492-1499
-
-
Forman-Kay, J.D.1
Mittag, T.2
-
33
-
-
84873315633
-
Characterization of disordered proteins with ENSEMBLE
-
Krzeminski M., Marsh J.A., Neale C., Choy W.-Y., Forman-Kay J.D. Characterization of disordered proteins with ENSEMBLE. Bioinformatics 2013, 29:398-399.
-
(2013)
Bioinformatics
, vol.29
, pp. 398-399
-
-
Krzeminski, M.1
Marsh, J.A.2
Neale, C.3
Choy, W.-Y.4
Forman-Kay, J.D.5
-
34
-
-
84898957660
-
The effect of intrachain electrostatic repulsion on conformational disorder and dynamics of the Sic1 protein
-
Liu B., Chia D., Csizmok V., Farber P., Forman-Kay J.D., Gradinaru C.C. The effect of intrachain electrostatic repulsion on conformational disorder and dynamics of the Sic1 protein. J Phys Chem B 2014, 118:4088-4097.
-
(2014)
J Phys Chem B
, vol.118
, pp. 4088-4097
-
-
Liu, B.1
Chia, D.2
Csizmok, V.3
Farber, P.4
Forman-Kay, J.D.5
Gradinaru, C.C.6
-
35
-
-
77956332835
-
Structural diversity in free and bound states of intrinsically disordered protein phosphatase 1 regulators
-
Marsh J.A., Dancheck B., Ragusa M.J., Allaire M., Forman-Kay J.D., Peti W. Structural diversity in free and bound states of intrinsically disordered protein phosphatase 1 regulators. Structure 2010, 18:1094-1103.
-
(2010)
Structure
, vol.18
, pp. 1094-1103
-
-
Marsh, J.A.1
Dancheck, B.2
Ragusa, M.J.3
Allaire, M.4
Forman-Kay, J.D.5
Peti, W.6
-
36
-
-
77951645923
-
Sequence determinants of compaction in intrinsically disordered proteins
-
Marsh J.A., Forman-Kay J.D. Sequence determinants of compaction in intrinsically disordered proteins. Biophys J 2010, 98:2383-2390.
-
(2010)
Biophys J
, vol.98
, pp. 2383-2390
-
-
Marsh, J.A.1
Forman-Kay, J.D.2
-
37
-
-
84855711579
-
Ensemble modeling of protein disordered states: experimental restraint contributions and validation
-
Marsh J.A., Forman-Kay J.D. Ensemble modeling of protein disordered states: experimental restraint contributions and validation. Proteins - Struct Funct Bioinform 2012, 80:556-572.
-
(2012)
Proteins - Struct Funct Bioinform
, vol.80
, pp. 556-572
-
-
Marsh, J.A.1
Forman-Kay, J.D.2
-
38
-
-
84882364963
-
Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues
-
Das R.K., Pappu R.V. Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues. Proc Natl Acad Sci USA 2013, 110:13392-13397.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 13392-13397
-
-
Das, R.K.1
Pappu, R.V.2
-
39
-
-
84885449854
-
A quantitative measure for protein conformational heterogeneity
-
Lyle N., Das R.K., Pappu R.V. A quantitative measure for protein conformational heterogeneity. J Chem Phys 2013, 139:121907.
-
(2013)
J Chem Phys
, vol.139
, pp. 121907
-
-
Lyle, N.1
Das, R.K.2
Pappu, R.V.3
-
40
-
-
77952335311
-
Net charge per residue modulates conformational ensembles of intrinsically disordered proteins
-
Mao A.H., Crick S.L., Vitalis A., Chicoine C.L., Pappu R.V. Net charge per residue modulates conformational ensembles of intrinsically disordered proteins. Proc Natl Acad Sci USA 2010, 107:8183-8188.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 8183-8188
-
-
Mao, A.H.1
Crick, S.L.2
Vitalis, A.3
Chicoine, C.L.4
Pappu, R.V.5
-
41
-
-
84871427941
-
Describing sequence-ensemble relationships for intrinsically disordered proteins
-
Mao A.H., Lyle N., Pappu R.V. Describing sequence-ensemble relationships for intrinsically disordered proteins. Biochem J 2013, 449:307-318.
-
(2013)
Biochem J
, vol.449
, pp. 307-318
-
-
Mao, A.H.1
Lyle, N.2
Pappu, R.V.3
-
42
-
-
79958029735
-
Evolution and disorder
-
Brown C.J., Johnson A.K., Dunker A.K., Daughdrill G.W. Evolution and disorder. Curr Opin Struct Biol 2011, 21:441-446.
-
(2011)
Curr Opin Struct Biol
, vol.21
, pp. 441-446
-
-
Brown, C.J.1
Johnson, A.K.2
Dunker, A.K.3
Daughdrill, G.W.4
-
43
-
-
84868118460
-
Chemical composition is maintained in poorly conserved intrinsically disordered regions and suggests a means for their classification
-
Moesa H.A., Wakabayashi S., Nakai K., Patil A. Chemical composition is maintained in poorly conserved intrinsically disordered regions and suggests a means for their classification. Mol BioSyst 2012, 8:3262-3273.
-
(2012)
Mol BioSyst
, vol.8
, pp. 3262-3273
-
-
Moesa, H.A.1
Wakabayashi, S.2
Nakai, K.3
Patil, A.4
-
44
-
-
84897057069
-
Single-molecule studies of intrinsically disordered proteins
-
Brucale M., Schuler B., Samori B. Single-molecule studies of intrinsically disordered proteins. Chem Rev 2014, 114:3281-3317.
-
(2014)
Chem Rev
, vol.114
, pp. 3281-3317
-
-
Brucale, M.1
Schuler, B.2
Samori, B.3
-
45
-
-
44949262123
-
Role of backbone - solvent interactions in determining conformational equilibria of intrinsically disordered proteins
-
Tran H.T., Mao A., Pappu R.V. Role of backbone - solvent interactions in determining conformational equilibria of intrinsically disordered proteins. J Am Chem Soc 2008, 130:7380-7392.
-
(2008)
J Am Chem Soc
, vol.130
, pp. 7380-7392
-
-
Tran, H.T.1
Mao, A.2
Pappu, R.V.3
-
46
-
-
84924303298
-
Quantitative assessments of the distinct contributions of polypeptide backbone amides versus side chain groups to chain expansion via chemical denaturation
-
Holehouse A.S., Garai K., Lyle N., Vitalis A., Pappu R.V. Quantitative assessments of the distinct contributions of polypeptide backbone amides versus side chain groups to chain expansion via chemical denaturation. J Am Chem Soc 2015, 137:2984-2995.
-
(2015)
J Am Chem Soc
, vol.137
, pp. 2984-2995
-
-
Holehouse, A.S.1
Garai, K.2
Lyle, N.3
Vitalis, A.4
Pappu, R.V.5
-
47
-
-
79955917231
-
Backbone-driven collapse in unfolded protein chains
-
Teufel D.P., Johnson C.M., Lum J.K., Neuweiler H. Backbone-driven collapse in unfolded protein chains. J Mol Biol 2011, 409:250-262.
-
(2011)
J Mol Biol
, vol.409
, pp. 250-262
-
-
Teufel, D.P.1
Johnson, C.M.2
Lum, J.K.3
Neuweiler, H.4
-
48
-
-
84906079367
-
Solubility and aggregation of Gly5 in water
-
Karandur D., Wong K.-Y., Pettitt B.M. Solubility and aggregation of Gly5 in water. J Phys Chem B 2014, 118:9565-9572.
-
(2014)
J Phys Chem B
, vol.118
, pp. 9565-9572
-
-
Karandur, D.1
Wong, K.-Y.2
Pettitt, B.M.3
-
50
-
-
0001237577
-
Phase transition behavior of the isolated polymer chain
-
Sanchez I.C. Phase transition behavior of the isolated polymer chain. Macromolecules 1979, 12:980-988.
-
(1979)
Macromolecules
, vol.12
, pp. 980-988
-
-
Sanchez, I.C.1
-
51
-
-
33750934185
-
Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions
-
Crick S.L., Jayaraman M., Frieden C., Wetzel R., Pappu R.V. Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions. Proc Natl Acad Sci USA 2006, 103:16764-16769.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 16764-16769
-
-
Crick, S.L.1
Jayaraman, M.2
Frieden, C.3
Wetzel, R.4
Pappu, R.V.5
-
52
-
-
84890288534
-
Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation
-
Crick S.L., Ruff K.M., Garai K., Frieden C., Pappu R.V. Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation. Proc Natl Acad Sci USA 2013, 110:20075-20080.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 20075-20080
-
-
Crick, S.L.1
Ruff, K.M.2
Garai, K.3
Frieden, C.4
Pappu, R.V.5
-
53
-
-
33847324863
-
A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures
-
Mukhopadhyay S., Krishnan R., Lemke E.A., Lindquist S., Deniz A.A. A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures. Proc Natl Acad Sci USA 2007, 104:2649-2654.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 2649-2654
-
-
Mukhopadhyay, S.1
Krishnan, R.2
Lemke, E.A.3
Lindquist, S.4
Deniz, A.A.5
-
54
-
-
64549131279
-
ABSINTH: a new continuum solvation model for simulations of polypeptides in aqueous solutions
-
Vitalis A., Pappu R.V. ABSINTH: a new continuum solvation model for simulations of polypeptides in aqueous solutions. J Comput Chem 2009, 30:673-699.
-
(2009)
J Comput Chem
, vol.30
, pp. 673-699
-
-
Vitalis, A.1
Pappu, R.V.2
-
55
-
-
84862278772
-
Improved atomistic Monte Carlo simulations demonstrate that poly-l-proline adopts heterogeneous ensembles of conformations of semi-rigid segments interrupted by kinks
-
Radhakrishnan A., Vitalis A., Mao A.H., Steffen A.T., Pappu R.V. Improved atomistic Monte Carlo simulations demonstrate that poly-l-proline adopts heterogeneous ensembles of conformations of semi-rigid segments interrupted by kinks. J Phys Chem B 2012, 116:6862-6871.
-
(2012)
J Phys Chem B
, vol.116
, pp. 6862-6871
-
-
Radhakrishnan, A.1
Vitalis, A.2
Mao, A.H.3
Steffen, A.T.4
Pappu, R.V.5
-
56
-
-
80052820089
-
Motion of a disordered polypeptide chain as studied by paramagnetic relaxation enhancements, 15N relaxation, and molecular dynamics simulations: how fast is segmental diffusion in denatured ubiquitin?
-
Xue Y., Skrynnikov N.R. Motion of a disordered polypeptide chain as studied by paramagnetic relaxation enhancements, 15N relaxation, and molecular dynamics simulations: how fast is segmental diffusion in denatured ubiquitin?. J Am Chem Soc 2011, 133:14614-14628.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 14614-14628
-
-
Xue, Y.1
Skrynnikov, N.R.2
-
57
-
-
82655179899
-
Structural analysis of intrinsically disordered proteins by small-angle X-ray scattering
-
Bernado P., Svergun D.I. Structural analysis of intrinsically disordered proteins by small-angle X-ray scattering. Mol BioSyst 2012, 8:151-167.
-
(2012)
Mol BioSyst
, vol.8
, pp. 151-167
-
-
Bernado, P.1
Svergun, D.I.2
-
58
-
-
84906277469
-
Hamiltonian Switch Metropolis Monte Carlo Simulations for improved conformational sampling of intrinsically disordered regions tethered to ordered domains of proteins
-
Mittal A., Lyle N., Harmon T.S., Pappu R.V. Hamiltonian Switch Metropolis Monte Carlo Simulations for improved conformational sampling of intrinsically disordered regions tethered to ordered domains of proteins. J Chem Theory Comput 2014, 10:3550-3562.
-
(2014)
J Chem Theory Comput
, vol.10
, pp. 3550-3562
-
-
Mittal, A.1
Lyle, N.2
Harmon, T.S.3
Pappu, R.V.4
-
60
-
-
0001189194
-
Flory theory of a polyampholyte chain
-
Dobrynin A.V., Rubinstein M. Flory theory of a polyampholyte chain. J Phys II 1995, 5:677-695.
-
(1995)
J Phys II
, vol.5
, pp. 677-695
-
-
Dobrynin, A.V.1
Rubinstein, M.2
-
61
-
-
33846099868
-
DisProt: the database of disordered proteins
-
Sickmeier M., Hamilton J.A., LeGall T., Vacic V., Cortese M.S., Tantos A., Szabo B., Tompa P., Chen J., Uversky V.N., et al. DisProt: the database of disordered proteins. Nucleic Acids Res 2007, 35:D786-D793.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. D786-D793
-
-
Sickmeier, M.1
Hamilton, J.A.2
LeGall, T.3
Vacic, V.4
Cortese, M.S.5
Tantos, A.6
Szabo, B.7
Tompa, P.8
Chen, J.9
Uversky, V.N.10
-
62
-
-
84921437702
-
Intrinsically disordered linker and plasma membrane-binding motif sort Ist2 and Ssy1 to junctions
-
Kralt A., Carretta M., Mari M., Reggiori F., Steen A., Poolman B., Veenhoff L.M. Intrinsically disordered linker and plasma membrane-binding motif sort Ist2 and Ssy1 to junctions. Traffic 2015, 16:135-147.
-
(2015)
Traffic
, vol.16
, pp. 135-147
-
-
Kralt, A.1
Carretta, M.2
Mari, M.3
Reggiori, F.4
Steen, A.5
Poolman, B.6
Veenhoff, L.M.7
-
63
-
-
84922371382
-
Intrinsically disordered C-terminal tails of E. coli single-stranded DNA binding protein regulate cooperative binding to single-stranded DNA
-
Kozlov A.G., Weiland E., Mittal A., Waldman V., Antony E., Fazio N., Pappu R.V., Lohman T.M. Intrinsically disordered C-terminal tails of E. coli single-stranded DNA binding protein regulate cooperative binding to single-stranded DNA. J Mol Biol 2015, 427:763-774.
-
(2015)
J Mol Biol
, vol.427
, pp. 763-774
-
-
Kozlov, A.G.1
Weiland, E.2
Mittal, A.3
Waldman, V.4
Antony, E.5
Fazio, N.6
Pappu, R.V.7
Lohman, T.M.8
-
64
-
-
84863743175
-
Human polyhomeotic homolog 3 (PHC3) sterile alpha motif (SAM) linker allows open-ended polymerization of PHC3 SAM
-
Robinson A.K., Leal B.Z., Nanyes D.R., Kaur Y., Ilangovan U., Schirf V., Hinck A.P., Demeler B., Kim C.A. Human polyhomeotic homolog 3 (PHC3) sterile alpha motif (SAM) linker allows open-ended polymerization of PHC3 SAM. Biochemistry 2012, 51:5379-5386.
-
(2012)
Biochemistry
, vol.51
, pp. 5379-5386
-
-
Robinson, A.K.1
Leal, B.Z.2
Nanyes, D.R.3
Kaur, Y.4
Ilangovan, U.5
Schirf, V.6
Hinck, A.P.7
Demeler, B.8
Kim, C.A.9
-
65
-
-
84866403056
-
Sweeping away protein aggregation with entropic bristles: intrinsically disordered protein fusions enhance soluble expression
-
Santner A.A., Croy C.H., Vasanwala F.H., Uversky V.N., Van Y.-Y.J., Dunker A.K. Sweeping away protein aggregation with entropic bristles: intrinsically disordered protein fusions enhance soluble expression. Biochemistry 2012, 51:7250-7262.
-
(2012)
Biochemistry
, vol.51
, pp. 7250-7262
-
-
Santner, A.A.1
Croy, C.H.2
Vasanwala, F.H.3
Uversky, V.N.4
Van, Y.-Y.J.5
Dunker, A.K.6
-
66
-
-
84884162953
-
RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability
-
Coussens M.A., Wendland R.L., Deriano L., Lindsay C.R., Arnal S.M., Roth D.B. RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability. Cell Rep 2013, 4:870-878.
-
(2013)
Cell Rep
, vol.4
, pp. 870-878
-
-
Coussens, M.A.1
Wendland, R.L.2
Deriano, L.3
Lindsay, C.R.4
Arnal, S.M.5
Roth, D.B.6
-
67
-
-
77954615134
-
A bimodal distribution of two distinct categories of intrinsically disordered structures with separate functions in FG nucleoporins
-
Yamada J., Phillips J.L., Patel S., Goldfien G., Calestagne-Morelli A., Huang H., Reza R., Acheson J., Krishnan V.V., Newsam S., et al. A bimodal distribution of two distinct categories of intrinsically disordered structures with separate functions in FG nucleoporins. Mol Cell Proteomics 2010, 9:2205-2224.
-
(2010)
Mol Cell Proteomics
, vol.9
, pp. 2205-2224
-
-
Yamada, J.1
Phillips, J.L.2
Patel, S.3
Goldfien, G.4
Calestagne-Morelli, A.5
Huang, H.6
Reza, R.7
Acheson, J.8
Krishnan, V.V.9
Newsam, S.10
-
68
-
-
82655175482
-
Attributes of short linear motifs
-
Davey N.E., Van Roey K., Weatheritt R.J., Toedt G., Uyar B., Altenberg B., Budd A., Diella F., Dinkel H., Gibson T.J. Attributes of short linear motifs. Mol BioSyst 2012, 8:268-281.
-
(2012)
Mol BioSyst
, vol.8
, pp. 268-281
-
-
Davey, N.E.1
Van Roey, K.2
Weatheritt, R.J.3
Toedt, G.4
Uyar, B.5
Altenberg, B.6
Budd, A.7
Diella, F.8
Dinkel, H.9
Gibson, T.J.10
-
69
-
-
84904469894
-
A million peptide motifs for the molecular biologist
-
Tompa P., Davey N.E., Gibson T.J., Babu M.M. A million peptide motifs for the molecular biologist. Mol Cell 2014, 55:161-169.
-
(2014)
Mol Cell
, vol.55
, pp. 161-169
-
-
Tompa, P.1
Davey, N.E.2
Gibson, T.J.3
Babu, M.M.4
-
70
-
-
84858267844
-
Proteome-wide discovery of evolutionary conserved sequences in disordered regions
-
Ba A.N.N., Yeh B.J., van Dyk D., Davidson A.R., Andrews B.J., Weiss E.L., Moses A.M. Proteome-wide discovery of evolutionary conserved sequences in disordered regions. Sci Signal 2012, 5.
-
(2012)
Sci Signal
, pp. 5
-
-
Ba, A.N.N.1
Yeh, B.J.2
van Dyk, D.3
Davidson, A.R.4
Andrews, B.J.5
Weiss, E.L.6
Moses, A.M.7
-
71
-
-
79955923819
-
Energy landscape analyses of disordered histone tails reveal special organization of their conformational dynamics
-
Potoyan D.A., Papoian G.A. Energy landscape analyses of disordered histone tails reveal special organization of their conformational dynamics. J Am Chem Soc 2011, 133:7405-7415.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 7405-7415
-
-
Potoyan, D.A.1
Papoian, G.A.2
-
72
-
-
78650453629
-
DNA search efficiency is modulated by charge composition and distribution in the intrinsically disordered tail
-
Vuzman D., Levy Y. DNA search efficiency is modulated by charge composition and distribution in the intrinsically disordered tail. Proc Natl Acad Sci USA 2010, 107:21004-21009.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 21004-21009
-
-
Vuzman, D.1
Levy, Y.2
-
73
-
-
0001416162
-
Sequence dependence of conformations of polyampholytes
-
Srivastava D., Muthukumar M. Sequence dependence of conformations of polyampholytes. Macromolecules 1996, 29:2324-2326.
-
(1996)
Macromolecules
, vol.29
, pp. 2324-2326
-
-
Srivastava, D.1
Muthukumar, M.2
-
74
-
-
84859824182
-
Disorder-function relationships for the cell cycle regulatory proteins p21 and p27
-
Mitrea D.M., Yoon M.K., Ou L., Kriwacki R.W. Disorder-function relationships for the cell cycle regulatory proteins p21 and p27. Biol Chem 2012, 393:259-274.
-
(2012)
Biol Chem
, vol.393
, pp. 259-274
-
-
Mitrea, D.M.1
Yoon, M.K.2
Ou, L.3
Kriwacki, R.W.4
-
75
-
-
42449123135
-
The effects of conformational heterogeneity on the binding of the Notch intracellular domain to effector proteins: a case of biologically tuned disorder
-
Bertagna A., Toptygin D., Brand L., Barrick D. The effects of conformational heterogeneity on the binding of the Notch intracellular domain to effector proteins: a case of biologically tuned disorder. Biochem Soc Trans 2008, 36:157-166.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 157-166
-
-
Bertagna, A.1
Toptygin, D.2
Brand, L.3
Barrick, D.4
-
76
-
-
84864459074
-
Dissecting and circumventing the requirement for RAM in CSL-dependent notch signaling
-
Johnson S.E., Barrick D. Dissecting and circumventing the requirement for RAM in CSL-dependent notch signaling. PLoS ONE 2012, 7:e39093.
-
(2012)
PLoS ONE
, vol.7
, pp. e39093
-
-
Johnson, S.E.1
Barrick, D.2
-
77
-
-
84866869780
-
Intrinsically disordered proteins aggregate at fungal cell-to-cell channels and regulate intercellular connectivity
-
Lai J., Koh C.H., Tjota M., Pieuchot L., Raman V., Chandrababu K.B., Yang D., Wong L., Jedd G. Intrinsically disordered proteins aggregate at fungal cell-to-cell channels and regulate intercellular connectivity. Proc Natl Acad Sci USA 2012, 109:15781-15786.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 15781-15786
-
-
Lai, J.1
Koh, C.H.2
Tjota, M.3
Pieuchot, L.4
Raman, V.5
Chandrababu, K.B.6
Yang, D.7
Wong, L.8
Jedd, G.9
-
78
-
-
84884696538
-
Polycation-pi interactions are a driving force for molecular recognition by an intrinsically disordered oncoprotein family
-
Song J., Ng S.C., Tompa P., Lee K.A.W., Chan H.S. Polycation-pi interactions are a driving force for molecular recognition by an intrinsically disordered oncoprotein family. PLoS Comput Biol 2013, 9:e1003239.
-
(2013)
PLoS Comput Biol
, vol.9
, pp. e1003239
-
-
Song, J.1
Ng, S.C.2
Tompa, P.3
Lee, K.A.W.4
Chan, H.S.5
-
79
-
-
84860826713
-
A core subunit of Polycomb repressive complex 1 is broadly conserved in function but not primary sequence
-
Beh L.Y., Colwell L.J., Francis N.J. A core subunit of Polycomb repressive complex 1 is broadly conserved in function but not primary sequence. Proc Natl Acad Sci USA 2012, 109:E1063-E1071.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. E1063-E1071
-
-
Beh, L.Y.1
Colwell, L.J.2
Francis, N.J.3
-
80
-
-
79959882243
-
Opposing effects of glutamine and asparagine govern prion formation by intrinsically disordered proteins
-
Halfmann R., Alberti S., Krishnan R., Lyle N., O'Donnell C.W., King O.D., Berger B., Pappu R.V., Lindquist S. Opposing effects of glutamine and asparagine govern prion formation by intrinsically disordered proteins. Mol Cell 2011, 43:72-84.
-
(2011)
Mol Cell
, vol.43
, pp. 72-84
-
-
Halfmann, R.1
Alberti, S.2
Krishnan, R.3
Lyle, N.4
O'Donnell, C.W.5
King, O.D.6
Berger, B.7
Pappu, R.V.8
Lindquist, S.9
-
81
-
-
84859565600
-
Peptide chain dynamics in light and heavy water: zooming in on internal friction
-
Schulz J.C.F., Schmidt L., Best R.B., Dzubiella J., Netz R.R. Peptide chain dynamics in light and heavy water: zooming in on internal friction. J Am Chem Soc 2012, 134:6273-6279.
-
(2012)
J Am Chem Soc
, vol.134
, pp. 6273-6279
-
-
Schulz, J.C.F.1
Schmidt, L.2
Best, R.B.3
Dzubiella, J.4
Netz, R.R.5
-
82
-
-
84862076708
-
Quantifying internal friction in unfolded and intrinsically disordered proteins with single-molecule spectroscopy
-
Soranno A., Buchli B., Nettels D., Cheng R.R., Mueller-Spaeth S., Pfeil S.H., Hoffmann A., Lipman E.A., Makarov D.E., Schuler B. Quantifying internal friction in unfolded and intrinsically disordered proteins with single-molecule spectroscopy. Proc Natl Acad Sci USA 2012, 109:17800-17806.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 17800-17806
-
-
Soranno, A.1
Buchli, B.2
Nettels, D.3
Cheng, R.R.4
Mueller-Spaeth, S.5
Pfeil, S.H.6
Hoffmann, A.7
Lipman, E.A.8
Makarov, D.E.9
Schuler, B.10
-
83
-
-
84903743025
-
Molecular origins of internal friction effects on protein-folding rates
-
de Sancho D., Sirur A., Best R.B. Molecular origins of internal friction effects on protein-folding rates. Nat Commun 2014, 5:4307.
-
(2014)
Nat Commun
, vol.5
, pp. 4307
-
-
de Sancho, D.1
Sirur, A.2
Best, R.B.3
-
84
-
-
84902664221
-
Concerted dihedral rotations give rise to internal friction in unfolded proteins
-
Echeverria I., Makarov D.E., Papoian G.A. Concerted dihedral rotations give rise to internal friction in unfolded proteins. J Am Chem Soc 2014, 136:8708-8713.
-
(2014)
J Am Chem Soc
, vol.136
, pp. 8708-8713
-
-
Echeverria, I.1
Makarov, D.E.2
Papoian, G.A.3
-
85
-
-
84859952526
-
Modulation of structure and dynamics by disulfide bond formation in unfolded states
-
Silvers R., Sziegat F., Tachibana H., Segawa S.-I., Whittaker S., Guenther U.L., Gabel F., Huang J.-R., Blackledge M., Wirmer-Bartoschek J., et al. Modulation of structure and dynamics by disulfide bond formation in unfolded states. J Am Chem Soc 2012, 134:6846-6854.
-
(2012)
J Am Chem Soc
, vol.134
, pp. 6846-6854
-
-
Silvers, R.1
Sziegat, F.2
Tachibana, H.3
Segawa, S.-I.4
Whittaker, S.5
Guenther, U.L.6
Gabel, F.7
Huang, J.-R.8
Blackledge, M.9
Wirmer-Bartoschek, J.10
-
86
-
-
85017728482
-
Protein conformational dynamics and molecular recognition in folded and unfolded proteins by NMR
-
Guerry P., Schneider R., Huang J.R., Delaforge E., Maurin D., Ozenne V., Communie G., Mollica L., Jensen M., Blackledge M. Protein conformational dynamics and molecular recognition in folded and unfolded proteins by NMR. Eur Biophys J Biophys Lett 2013, 42:S61.
-
(2013)
Eur Biophys J Biophys Lett
, vol.42
, pp. S61
-
-
Guerry, P.1
Schneider, R.2
Huang, J.R.3
Delaforge, E.4
Maurin, D.5
Ozenne, V.6
Communie, G.7
Mollica, L.8
Jensen, M.9
Blackledge, M.10
-
87
-
-
70450237199
-
Toward a unified representation of protein structural dynamics in solution
-
Markwick P.R.L., Bouvignies G., Salmon L., McCammon J.A., Nilges M., Blackledge M. Toward a unified representation of protein structural dynamics in solution. J Am Chem Soc 2009, 131:16968-16975.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 16968-16975
-
-
Markwick, P.R.L.1
Bouvignies, G.2
Salmon, L.3
McCammon, J.A.4
Nilges, M.5
Blackledge, M.6
-
88
-
-
76649114676
-
Protein dynamics and conformational disorder in molecular recognition
-
Mittag T., Kay L.E., Forman-Kay J.D. Protein dynamics and conformational disorder in molecular recognition. J Mol Recognit 2010, 23:105-116.
-
(2010)
J Mol Recognit
, vol.23
, pp. 105-116
-
-
Mittag, T.1
Kay, L.E.2
Forman-Kay, J.D.3
-
89
-
-
84864424878
-
Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 binding
-
Andresen C., Helander S., Lemak A., Fares C., Csizmok V., Carlsson J., Penn L.Z., Forman-Kay J.D., Arrowsmith C.H., Lundstrom P., et al. Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 binding. Nucleic Acids Res 2012, 40:6353-6366.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 6353-6366
-
-
Andresen, C.1
Helander, S.2
Lemak, A.3
Fares, C.4
Csizmok, V.5
Carlsson, J.6
Penn, L.Z.7
Forman-Kay, J.D.8
Arrowsmith, C.H.9
Lundstrom, P.10
-
90
-
-
84922756480
-
Ultrafast cooling reveals microsecond-scale biomolecular dynamics
-
Polinkovsky M.E., Gambin Y., Banerjee P.R., Erickstad M.J., Groisman A., Deniz A.A. Ultrafast cooling reveals microsecond-scale biomolecular dynamics. Nat Commun 2014, 5:5737.
-
(2014)
Nat Commun
, vol.5
, pp. 5737
-
-
Polinkovsky, M.E.1
Gambin, Y.2
Banerjee, P.R.3
Erickstad, M.J.4
Groisman, A.5
Deniz, A.A.6
-
91
-
-
84870852782
-
A toolkit and benchmark study for FRET-restrained high-precision structural modeling
-
Kalinin S., Peulen T., Sindbert S., Rothwell P.J., Berger S., Restle T., Goody R.S., Gohlke H., Seidel C.A.M. A toolkit and benchmark study for FRET-restrained high-precision structural modeling. Nat Methods 2012, 9:U1129-U1218.
-
(2012)
Nat Methods
, vol.9
, pp. U1129-U1218
-
-
Kalinin, S.1
Peulen, T.2
Sindbert, S.3
Rothwell, P.J.4
Berger, S.5
Restle, T.6
Goody, R.S.7
Gohlke, H.8
Seidel, C.A.M.9
-
92
-
-
84948949784
-
Fine tuning of sub-millisecond conformational dynamics controls metabotropic glutamate receptors agonist efficacy
-
Olofsson L., Felekyan S., Doumazane E., Scholler P., Fabre L., Zwier J.M., Rondard P., Seidel C.A.M., Pin J.-P., Margeat E. Fine tuning of sub-millisecond conformational dynamics controls metabotropic glutamate receptors agonist efficacy. Nat Commun 2014, 5:5206.
-
(2014)
Nat Commun
, vol.5
, pp. 5206
-
-
Olofsson, L.1
Felekyan, S.2
Doumazane, E.3
Scholler, P.4
Fabre, L.5
Zwier, J.M.6
Rondard, P.7
Seidel, C.A.M.8
Pin, J.-P.9
Margeat, E.10
-
93
-
-
0036424048
-
Transition path sampling: throwing ropes over rough mountain passes, in the dark
-
Bolhuis P.G., Chandler D., Dellago C., Geissler P.L. Transition path sampling: throwing ropes over rough mountain passes, in the dark. Annu Rev Phys Chem 2002, 53:291-318.
-
(2002)
Annu Rev Phys Chem
, vol.53
, pp. 291-318
-
-
Bolhuis, P.G.1
Chandler, D.2
Dellago, C.3
Geissler, P.L.4
-
94
-
-
79952117460
-
Overcoming barriers in trajectory space: mechanism and kinetics of rare events via Wang-Landau enhanced transition path sampling
-
Borrero E.E., Dellago C. Overcoming barriers in trajectory space: mechanism and kinetics of rare events via Wang-Landau enhanced transition path sampling. J Chem Phys 2010, 133:134112.
-
(2010)
J Chem Phys
, vol.133
, pp. 134112
-
-
Borrero, E.E.1
Dellago, C.2
-
95
-
-
84859551481
-
Transition path sampling of protein conformational changes
-
Juraszek J., Vreede J., Bolhuis P.G. Transition path sampling of protein conformational changes. Chem Phys 2012, 396:30-44.
-
(2012)
Chem Phys
, vol.396
, pp. 30-44
-
-
Juraszek, J.1
Vreede, J.2
Bolhuis, P.G.3
-
96
-
-
84922480425
-
Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells
-
Borcherds W., Theillet F.-X., Katzer A., Finzel A., Mishall K.M., Powell A.T., Wu H., Manieri W., Dieterich C., Selenko P., et al. Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells. Nat Chem Biol 2014, 10:1000-1002.
-
(2014)
Nat Chem Biol
, vol.10
, pp. 1000-1002
-
-
Borcherds, W.1
Theillet, F.-X.2
Katzer, A.3
Finzel, A.4
Mishall, K.M.5
Powell, A.T.6
Wu, H.7
Manieri, W.8
Dieterich, C.9
Selenko, P.10
-
97
-
-
84879327823
-
Modulation of allostery by protein intrinsic disorder
-
Ferreon A.C.M., Ferreon J.C., Wright P.E., Deniz A.A. Modulation of allostery by protein intrinsic disorder. Nature 2013, 498:390-394.
-
(2013)
Nature
, vol.498
, pp. 390-394
-
-
Ferreon, A.C.M.1
Ferreon, J.C.2
Wright, P.E.3
Deniz, A.A.4
|