-
1
-
-
56749184298
-
Reflecting on 25 years with MYC
-
Meyer, N. and Penn, L.Z. (2008) Reflecting on 25 years with MYC. Nat. Rev. Cancer, 8, 976-990.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 976-990
-
-
Meyer, N.1
Penn, L.Z.2
-
2
-
-
54349087788
-
Myc's broad reach
-
Eilers, M. and Eisenman, R.N. (2008) Myc's broad reach. Genes Dev., 22, 2755-2766.
-
(2008)
Genes Dev
, vol.22
, pp. 2755-2766
-
-
Eilers, M.1
Eisenman, R.N.2
-
3
-
-
78650336901
-
Proteomic profiling of Myc-associated proteins
-
Agrawal, P., Yu, K., Salomon, A.R. and Sedivy, J.M. (2010) Proteomic profiling of Myc-associated proteins. Cell Cycle, 9, 4908-4921.
-
(2010)
Cell Cycle
, vol.9
, pp. 4908-4921
-
-
Agrawal, P.1
Yu, K.2
Salomon, A.R.3
Sedivy, J.M.4
-
4
-
-
77957757417
-
A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs
-
Kim, J., Woo, A.J., Chu, J., Snow, J.W., Fujiwara, Y., Kim, C.G., Cantor, A.B. and Orkin, S.H. (2010) A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs. Cell, 143, 313-324.
-
(2010)
Cell
, vol.143
, pp. 313-324
-
-
Kim, J.1
Woo, A.J.2
Chu, J.3
Snow, J.W.4
Fujiwara, Y.5
Kim, C.G.6
Cantor, A.B.7
Orkin, S.H.8
-
5
-
-
79851502865
-
More than MAX: Discovering the myc interactome
-
Kalkat, M., Wasylishen, A.R., Kim, S.S. and Penn, L. (2011) More than MAX: discovering the Myc interactome. Cell Cycle, 10, 374-379.
-
(2011)
Cell Cycle
, vol.10
, pp. 374-379
-
-
Kalkat, M.1
Wasylishen, A.R.2
Kim, S.S.3
Penn, L.4
-
6
-
-
0037462459
-
X-ray structures of Myc-max and mad-max recognizing DNA: Molecular bases of regulation by proto-oncogenic transcription factors
-
Nair, S.K. and Burley, S.K. (2003) X-ray structures of Myc-Max and Mad-Max recognizing DNA: molecular bases of regulation by proto-oncogenic transcription factors. Cell, 112, 193-205.
-
(2003)
Cell
, vol.112
, pp. 193-205
-
-
Nair, S.K.1
Burley, S.K.2
-
7
-
-
33748171960
-
The C-myc target gene network
-
Dang, C.V., O'Donnell, K.A., Zeller, K.I., Nguyen, T., Osthus, R.C. and Li, F. (2006) The C-Myc target gene network. Semin. Cancer Biol., 16, 253-264.
-
(2006)
Semin. Cancer Biol
, vol.16
, pp. 253-264
-
-
Dang, C.V.1
O'Donnell, K.A.2
Zeller, K.I.3
Nguyen, T.4
Osthus, R.C.5
Li, F.6
-
8
-
-
79952842708
-
Enigmatic MYC conducts an unfolding systems biology symphony
-
Dang, C.V. (2010) Enigmatic MYC conducts an unfolding systems biology symphony. Genes Cancer, 1, 526-531.
-
(2010)
Genes Cancer
, vol.1
, pp. 526-531
-
-
Dang, C.V.1
-
9
-
-
52449101436
-
Transcription-independent functions of MYC: Regulation of translation and DNA replication
-
Cole, M.D. and Cowling, V.H. (2008) Transcription-independent functions of MYC: regulation of translation and DNA replication. Nat. Rev. Mol. Cell Biol., 9, 810-815.
-
(2008)
Nat. Rev. Mol. Cell Biol
, vol.9
, pp. 810-815
-
-
Cole, M.D.1
Cowling, V.H.2
-
10
-
-
0025166030
-
An amino-terminal C-MYC domain required for neoplastic transformation activates transcription
-
Kato, G.J., Barrett, J., Villa-Garcia, M. and Dang, C.V. (1990) An amino-terminal C-MYC domain required for neoplastic transformation activates transcription. Mol. Cell. Biol., 10, 5914-5920.
-
(1990)
Mol. Cell. Biol
, vol.10
, pp. 5914-5920
-
-
Kato, G.J.1
Barrett, J.2
Villa-Garcia, M.3
Dang, C.V.4
-
11
-
-
0023116071
-
Definition of regions in human C-MYC that are involved in transformation and nuclear localization
-
Stone, J., de Lange, T., Ramsay, G., Jakobovits, E., Bishop, J.M., Varmus, H. and Lee, W. (1987) Definition of regions in human C-MYC that are involved in transformation and nuclear localization. Mol. Cell. Biol., 7, 1697-1709.
-
(1987)
Mol. Cell. Biol
, vol.7
, pp. 1697-1709
-
-
Stone, J.1
De Lange, T.2
Ramsay, G.3
Jakobovits, E.4
Bishop, J.M.5
Varmus, H.6
Lee, W.7
-
12
-
-
0025461390
-
Definition of the activities and properties of C-MYC required to inhibit cell differentiation
-
Freytag, S., Dang, C. and Lee, W. (1990) Definition of the activities and properties of C-MYC required to inhibit cell differentiation. Cell Growth Differ., 1, 339-343.
-
(1990)
Cell Growth Differ
, vol.1
, pp. 339-343
-
-
Freytag, S.1
Dang, C.2
Lee, W.3
-
13
-
-
0026642195
-
Induction of apoptosis in fibroblasts by C-MYC protein
-
Evan, G.I., Wyllie, A.H., Gilbert, C.S., Littlewood, T.D., Land, H., Brooks, M., Waters, C.M., Penn, L.Z. and Hancock, D.C. (1992) Induction of apoptosis in fibroblasts by C-MYC protein. Cell, 69, 119-128.
-
(1992)
Cell
, vol.69
, pp. 119-128
-
-
Evan, G.I.1
Wyllie, A.H.2
Gilbert, C.S.3
Littlewood, T.D.4
Land, H.5
Brooks, M.6
Waters, C.M.7
Penn, L.Z.8
Hancock, D.C.9
-
14
-
-
70350233471
-
Acting locally and globally: Myc's ever-expanding roles on chromatin
-
Varlakhanova, N.V. and Knoepfler, P.S. (2009) Acting locally and globally: Myc's ever-expanding roles on chromatin. Cancer Res., 69, 7487-7490.
-
(2009)
Cancer Res
, vol.69
, pp. 7487-7490
-
-
Varlakhanova, N.V.1
Knoepfler, P.S.2
-
15
-
-
77949920493
-
MYC as a regulator of ribosome biogenesis and protein synthesis
-
van Riggelen, J., Yetil, A. and Felsher, D.W. (2010) MYC as a regulator of ribosome biogenesis and protein synthesis. Nat. Rev. Cancer, 10, 301-309.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 301-309
-
-
Van Riggelen, J.1
Yetil, A.2
Felsher, D.W.3
-
16
-
-
33748145149
-
Mechanism of transcriptional activation by the Myc oncoproteins
-
Cowling, V.H. and Cole, M.D. (2006) Mechanism of transcriptional activation by the Myc oncoproteins. Semin. Cancer Biol., 16, 242-252.
-
(2006)
Semin. Cancer Biol
, vol.16
, pp. 242-252
-
-
Cowling, V.H.1
Cole, M.D.2
-
17
-
-
2342526543
-
A signalling pathway controlling C-MYC degradation that impacts oncogenic transformation of human cells
-
Yeh, E., Cunningham, M., Arnold, H., Chasse, D., Monteith, T., Ivaldi, G., Hahn, W.C., Stukenberg, P.T., Shenolikar, S., Uchida, T. et al. (2004) A signalling pathway controlling C-MYC degradation that impacts oncogenic transformation of human cells. Nat. Cell Biol., 6, 308-318.
-
(2004)
Nat. Cell Biol
, vol.6
, pp. 308-318
-
-
Yeh, E.1
Cunningham, M.2
Arnold, H.3
Chasse, D.4
Monteith, T.5
Ivaldi, G.6
Hahn, W.C.7
Stukenberg, P.T.8
Shenolikar, S.9
Uchida, T.10
-
18
-
-
33748138585
-
Role of post-translational modifications in regulating C-MYC proteolysis, transcriptional activity and biological function
-
Hann, S.R. (2006) Role of post-translational modifications in regulating C-MYC proteolysis, transcriptional activity and biological function. Semin. Cancer Biol., 16, 288-302.
-
(2006)
Semin. Cancer Biol
, vol.16
, pp. 288-302
-
-
Hann, S.R.1
-
19
-
-
76249101395
-
Phosphorylation by CDK2 is required for Myc to repress Ras-induced senescence in cotransformation
-
Hydbring, P., Bahram, F., Su, Y., Tronnersjö, S., Högstrand, K., von der Lehr, N., Sharifi, H.R., Lilischkis, R., Hein, N., Wu, S. et al. (2010) Phosphorylation by CDK2 is required for Myc to repress Ras-induced senescence in cotransformation. Proc. Natl Acad. Sci. USA, 107, 58-63.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 58-63
-
-
Hydbring, P.1
Bahram, F.2
Su, Y.3
Tronnersjö, S.4
Högstrand, K.5
Von Der Lehr, N.6
Sharifi, H.R.7
Lilischkis, R.8
Hein, N.9
Wu, S.10
-
20
-
-
33845919326
-
The ins and outs of Myc regulation by posttranslational mechanisms
-
Vervoorts, J., Lüscher-Firzlaff, J. and Lüscher, B. (2006) The ins and outs of Myc regulation by posttranslational mechanisms. J. Biol. Chem., 281, 34725-34729.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 34725-34729
-
-
Vervoorts, J.1
Lüscher-Firzlaff, J.2
Lüscher, B.3
-
21
-
-
0034653998
-
C-MYC hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover
-
Bahram, F., von der Lehr, N., Cetinkaya, C. and Larsson, L.-G. (2000) C-MYC hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover. Blood, 95, 2104-2110.
-
(2000)
Blood
, vol.95
, pp. 2104-2110
-
-
Bahram, F.1
Von Der Lehr, N.2
Cetinkaya, C.3
Larsson, L.-G.4
-
22
-
-
79551552058
-
Phosphorylation regulates C-Myc's oncogenic activity in the mammary gland
-
Wang, X., Cunningham, M., Zhang, X., Tokarz, S., Laraway, B., Troxell, M. and Sears, R.C. (2011) Phosphorylation regulates C-Myc's oncogenic activity in the mammary gland. Cancer Res., 71, 925-936.
-
(2011)
Cancer Res
, vol.71
, pp. 925-936
-
-
Wang, X.1
Cunningham, M.2
Zhang, X.3
Tokarz, S.4
Laraway, B.5
Troxell, M.6
Sears, R.C.7
-
23
-
-
38549086019
-
FBW7 ubiquitin ligase: A tumour suppressor at the crossroads of cell division, growth and differentiation
-
Welcker, M. and Clurman, B.E. (2008) FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. Nat. Rev. Cancer, 8, 83-93.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 83-93
-
-
Welcker, M.1
Clurman, B.E.2
-
24
-
-
22044446356
-
A structure-based model of the C-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and C-Myc phosphorylation are key binding determinants
-
Pineda-Lucena, A., Ho, C.S.W., Mao, D.Y.L., Sheng, Y., Laister, R.C., Muhandiram, R., Lu, Y., Seet, B.T., Katz, S., Szyperski, T. et al. (2005) A structure-based model of the C-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and C-Myc phosphorylation are key binding determinants. J. Mol. Biol., 351, 182-194.
-
(2005)
J. Mol. Biol
, vol.351
, pp. 182-194
-
-
Pineda-Lucena, A.1
Ho, C.S.W.2
Mao, D.Y.L.3
Sheng, Y.4
Laister, R.C.5
Muhandiram, R.6
Lu, Y.7
Seet, B.T.8
Katz, S.9
Szyperski, T.10
-
25
-
-
0029741917
-
BIN1 is a novel Myc-interacting protein with features of a tumour suppressor
-
Sakamuro, D., Elliott, K.J., Wechsler-Reya, R. and Prendergast, G.C. (1996) BIN1 is a novel Myc-interacting protein with features of a tumour suppressor. Nat. Genet., 14, 69-77.
-
(1996)
Nat. Genet
, vol.14
, pp. 69-77
-
-
Sakamuro, D.1
Elliott, K.J.2
Wechsler-Reya, R.3
Prendergast, G.C.4
-
26
-
-
0034074925
-
Loss of heterozygosity and tumor suppressor activity of BIN1 in prostate carcinoma
-
Ge, K., Minhas, F., Duhadaway, J., Mao, N.-C., Wilson, D., Buccafusca, R., Sakamuro, D., Nelson, P., Malkowicz, S.B., Tomaszewski, J. et al. (2000) Loss of heterozygosity and tumor suppressor activity of BIN1 in prostate carcinoma. Int. J. Cancer, 86, 155-161.
-
(2000)
Int. J. Cancer
, vol.86
, pp. 155-161
-
-
Ge, K.1
Minhas, F.2
Duhadaway, J.3
Mao, N.-C.4
Wilson, D.5
Buccafusca, R.6
Sakamuro, D.7
Nelson, P.8
Malkowicz, S.B.9
Tomaszewski, J.10
-
27
-
-
0033577992
-
BIN1 functionally interacts with Myc and inhibits cell proliferation via multiple mechanisms
-
Elliott, K., Sakamuro, D., Basu, A., Du, W., Wunner, W., Staller, P., Gaubatz, S., Zhang, H., Prochownik, E., Eilers, M. et al. (1999) BIN1 functionally interacts with Myc and inhibits cell proliferation via multiple mechanisms. Oncogene, 18, 3564-3573.
-
(1999)
Oncogene
, vol.18
, pp. 3564-3573
-
-
Elliott, K.1
Sakamuro, D.2
Du Basu, A.W.3
Wunner, W.4
Staller, P.5
Gaubatz, S.6
Zhang, H.7
Prochownik, E.8
Eilers, M.9
-
28
-
-
0035300436
-
BIN1 mediates apoptosis by C-Myc in transformed primary cells
-
DuHadaway, J.B., Sakamuro, D., Ewert, D.L. and Prendergast, G.C. (2001) BIN1 mediates apoptosis by C-Myc in transformed primary cells. Cancer Res., 61, 3151-3156.
-
(2001)
Cancer Res
, vol.61
, pp. 3151-3156
-
-
DuHadaway, J.B.1
Sakamuro, D.2
Ewert, D.L.3
Prendergast, G.C.4
-
29
-
-
13844250478
-
Suppression of MEK/ERK signalling by Mcy: Role of Bin-1
-
Telfer, J.F., Urquhart, J. and Crouch, D.H. (2005) Suppression of MEK/ERK signalling by Mcy: role of Bin-1. Cell. Signalling, 17, 701-708.
-
(2005)
Cell. Signalling
, vol.17
, pp. 701-708
-
-
Telfer, J.F.1
Urquhart, J.2
Crouch, D.H.3
-
30
-
-
48749107576
-
Adenovirus E1A oncoprotein liberates C-Mcy activity to promote cell proliferation through abating BIN1 expression via an RB/E2F1-dependent mechanism
-
Kinney, E.L., Tanida, S., Rodrigue, A.A., Johnson, J.K., Tompkins, V.S. and Sakamuro, D. (2008) Adenovirus E1A oncoprotein liberates C-Mcy activity to promote cell proliferation through abating BIN1 expression via an RB/E2F1-dependent mechanism. J. Cell. Physiol., 216, 621-631.
-
(2008)
J. Cell. Physiol
, vol.216
, pp. 621-631
-
-
Kinney, E.L.1
Tanida, S.2
Rodrigue, A.A.3
Johnson, J.K.4
Tompkins, V.S.5
Sakamuro, D.6
-
31
-
-
12344276756
-
N and C-terminal sub-regions in the C-Mcy transactivation region and their joint role in creating versatility in folding and binding
-
Fladvad, M., Zhou, K.S., Moshref, A., Pursglove, S., Safsten, P. and Sunnerhagen, M. (2005) N and C-terminal sub-regions in the C-Mcy transactivation region and their joint role in creating versatility in folding and binding. J. Mol. Biol., 346, 175-189.
-
(2005)
J. Mol. Biol
, vol.346
, pp. 175-189
-
-
Fladvad, M.1
Zhou, K.S.2
Moshref, A.3
Pursglove, S.4
Safsten, P.5
Sunnerhagen, M.6
-
32
-
-
14644435825
-
Intrinsically unstructured proteins and their functions
-
Dyson, H.J. and Wright, P.E. (2005) Intrinsically unstructured proteins and their functions. Nat. Rev. Mol. Cell Biol., 6, 197-208.
-
(2005)
Nat. Rev. Mol. Cell Biol
, vol.6
, pp. 197-208
-
-
Dyson, H.J.1
Wright, P.E.2
-
33
-
-
76649114676
-
Protein dynamics and conformational disorder in molecular recognition
-
Mittag, T., Kay, L.E. and Forman-Kay, J.D. (2010) Protein dynamics and conformational disorder in molecular recognition. J. Mol. Recognit., 23, 105-116.
-
(2010)
J. Mol. Recognit
, vol.23
, pp. 105-116
-
-
Mittag, T.1
Kay, L.E.2
Forman-Kay, J.D.3
-
34
-
-
0029740873
-
Functional interaction of the C-Mcy transactivation domain with the TATA binding protein: Evidence for an induced fit model of transactivation domain folding
-
McEwan, I.J., Dahlman-Wright, K., Ford, J. and Wright, A.P.H. (1996) Functional interaction of the C-Mcy transactivation domain with the TATA binding protein: evidence for an induced fit model of transactivation domain folding. Biochemistry, 35, 9584-9593.
-
(1996)
Biochemistry
, vol.35
, pp. 9584-9593
-
-
McEwan, I.J.1
Dahlman-Wright, K.2
Ford, J.3
Wright, A.P.H.4
-
35
-
-
33747476839
-
B-Mcy: N-terminal recognition of Mcy binding proteins
-
Burton, R.A., Mattila, S., Taparowsky, E.J. and Post, C.B. (2006) B-Mcy: N-terminal recognition of Mcy binding proteins. Biochemistry, 45, 9857-9865.
-
(2006)
Biochemistry
, vol.45
, pp. 9857-9865
-
-
Burton, R.A.1
Mattila, S.2
Taparowsky, E.J.3
Post, C.B.4
-
36
-
-
27544456436
-
Cancer therapeutics: Targeting the dark side of Mcy
-
Ponzielli, R., Katz, S., Barsyte-Lovejoy, D. and Penn, L.Z. (2005) Cancer therapeutics: targeting the dark side of Mcy. Eur. J. Cancer, 41, 2485-2501.
-
(2005)
Eur. J. Cancer
, vol.41
, pp. 2485-2501
-
-
Ponzielli, R.1
Katz, S.2
Barsyte-Lovejoy, D.3
Penn, L.Z.4
-
37
-
-
2942614705
-
Phosphorylation-dependent degradation of C-Mcy is mediated by the F-box protein FBW7
-
Yada, M., Hatakeyama, S., Kamura, T., Nishiyama, M., Tsunematsu, R., Imaki, H., Ishida, N., Okumura, F., Nakayama, K. and Nakayama, K.I. (2004) Phosphorylation-dependent degradation of C-Mcy is mediated by the F-box protein Fbw7. EMBO J., 23, 2116-2125.
-
(2004)
EMBO J
, vol.23
, pp. 2116-2125
-
-
Yada, M.1
Hatakeyama, S.2
Kamura, T.3
Nishiyama, M.4
Tsunematsu, R.5
Imaki, H.6
Ishida, N.7
Okumura, F.8
Nakayama, K.9
Nakayama, K.I.10
-
38
-
-
62049085035
-
The Axin1 scaffold protein promotes formation of a degradation complex for C-Mcy
-
Arnold, H.K., Zhang, X., Daniel, C.J., Tibbitts, D., Escamilla-Powers, J., Farrell, A., Tokarz, S., Morgan, C. and Sears, R.C. (2009) The Axin1 scaffold protein promotes formation of a degradation complex for C-Mcy. EMBO J., 28, 500-512.
-
(2009)
EMBO J
, vol.28
, pp. 500-512
-
-
Arnold, H.K.1
Zhang, X.2
Daniel, C.J.3
Tibbitts, D.4
Escamilla-Powers, J.5
Farrell, A.6
Tokarz, S.7
Morgan, C.8
Sears, R.C.9
-
39
-
-
80052326351
-
NMR spectroscopy to study the dynamics and interactions of CFTR
-
Kanelis, V., Chong, P.A. and Forman-Kay, J.D. (2011) NMR spectroscopy to study the dynamics and interactions of CFTR. Methods Mol Biol, 741, 377-403.
-
(2011)
Methods Mol Biol
, vol.741
, pp. 377-403
-
-
Kanelis, V.1
Chong, P.A.2
Forman-Kay, J.D.3
-
40
-
-
79951553142
-
A novel strategy for NMR resonance assignment and protein structure determination
-
Lemak, A., Gutmanas, A., Chitayat, S., Karra, M., Farè s, C., Sunnerhagen, M. and Arrowsmith, C. (2011) A novel strategy for NMR resonance assignment and protein structure determination. J. Biomol. NMR, 49, 27-38.
-
(2011)
J. Biomol. NMR
, vol.49
, pp. 27-38
-
-
Lemak, A.1
Gutmanas, A.2
Chitayat, S.3
Karra, M.4
Farè, S.C.5
Sunnerhagen, M.6
Arrowsmith, C.7
-
41
-
-
0028282555
-
Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation
-
Farrow, N.A., Muhandiram, R., Singer, A.U., Pascal, S.M., Kay, C.M., Gish, G., Shoelson, S.E., Pawson, T., Forman-Kay, J.D. and Kay, L.E. (1994) Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation. Biochemistry, 33, 5984-6003.
-
(1994)
Biochemistry
, vol.33
, pp. 5984-6003
-
-
Farrow, N.A.1
Muhandiram, R.2
Singer, A.U.3
Pascal, S.M.4
Kay, C.M.5
Gish, G.6
Shoelson, S.E.7
Pawson, T.8
Forman-Kay, J.D.9
Kay, L.E.10
-
42
-
-
0037063506
-
An NMR experiment for the accurate measurement of heteronuclear spin-lock relaxation rates
-
Korzhnev, D.M., Skrynnikov, N.R., Millet, O., Torchia, D.A. and Kay, L.E. (2002) An NMR experiment for the accurate measurement of heteronuclear spin-lock relaxation rates. J. Am. Chem. Soc., 124, 10743-10753.
-
(2002)
J. Am. Chem. Soc
, vol.124
, pp. 10743-10753
-
-
Korzhnev, D.M.1
Skrynnikov, N.R.2
Millet, O.3
Torchia, D.A.4
Kay, L.E.5
-
43
-
-
0029400480
-
Nmrpipe: A multidimensional spectral processing system based on UNIX pipes
-
Delaglio, F., Grzesiek, S., Vuister, G.W., Zhu, G., Pfeifer, J. and Bax, A. (1995) NMRPipe: A multidimensional spectral processing system based on UNIX pipes. J. Biomol. NMR, 6, 277-293.
-
(1995)
J. Biomol. NMR
, vol.6
, pp. 277-293
-
-
Delaglio, F.1
Grzesiek, S.2
Vuister, G.W.3
Zhu, G.4
Pfeifer, J.5
Bax, A.6
-
45
-
-
0033543577
-
Altered flexibility in the substrate-binding site of related native and engineered high-alkaline bacillus subtilisins
-
Mulder, F.A.A., Schipper, D., Bott, R. and Boelens, R. (1999) Altered flexibility in the substrate-binding site of related native and engineered high-alkaline Bacillus subtilisins. J. Mol. Biol., 292, 111-123.
-
(1999)
J. Mol. Biol
, vol.292
, pp. 111-123
-
-
Mulder, F.A.A.1
Schipper, D.2
Bott, R.3
Boelens, R.4
-
46
-
-
35848958773
-
Combined chemical shift changes and amino acid specific chemical shift mapping of protein-protein interactions
-
Schumann, F., Riepl, H., Maurer, T., Gronwald, W., Neidig, K.-P. and Kalbitzer, H. (2007) Combined chemical shift changes and amino acid specific chemical shift mapping of protein-protein interactions. J. Biomol. NMR, 39, 275-289.
-
(2007)
J. Biomol. NMR
, vol.39
, pp. 275-289
-
-
Schumann, F.1
Riepl, H.2
Maurer, T.3
Gronwald, W.4
Neidig, K.-P.5
Kalbitzer, H.6
-
47
-
-
33751552347
-
Sensitivity of secondary structure propensities to sequence differences between A-and G-synuclein: Implications for fibrillation
-
Marsh, J.A., Singh, V.K., Jia, Z. and Forman-Kay, J.D. (2006) Sensitivity of secondary structure propensities to sequence differences between A-and G-synuclein: Implications for fibrillation. Protein Sci., 15, 2795-2804.
-
(2006)
Protein Sci
, vol.15
, pp. 2795-2804
-
-
Marsh, J.A.1
Singh, V.K.2
Jia, Z.3
Forman-Kay, J.D.4
-
49
-
-
33744908076
-
Characterization of the dynamics of biomacromolecules using rotating-frame spin relaxation NMR spectroscopy
-
Palmer, A.G. and Massi, F. (2006) Characterization of the dynamics of biomacromolecules using rotating-frame spin relaxation NMR spectroscopy. Chem. Rev., 106, 1700-1719.
-
(2006)
Chem. Rev
, vol.106
, pp. 1700-1719
-
-
Palmer, A.G.1
Massi, F.2
-
51
-
-
77249137740
-
BRICHOS - A superfamily of multidomain proteins with diverse functions
-
Hedlund, J., Johansson, J. and Persson, B. (2009) BRICHOS-a superfamily of multidomain proteins with diverse functions. BMC Res. Notes, 2, 180.
-
(2009)
BMC Res. Notes
, vol.2
, pp. 180
-
-
Hedlund, J.1
Johansson, J.2
Persson, B.3
-
52
-
-
68749093787
-
Predicting intrinsic disorder in proteins: An overview
-
He, B., Wang, K., Liu, Y., Xue, B., Uversky, V.N. and Dunker, A.K. (2009) Predicting intrinsic disorder in proteins: an overview. Cell Res., 19, 929-949.
-
(2009)
Cell Res
, vol.19
, pp. 929-949
-
-
He, B.1
Wang, K.2
Liu, Y.3
Xue, B.4
Uversky, V.N.5
Dunker, A.K.6
-
53
-
-
0242458482
-
Protein disorder prediction: Implications for structural proteomics
-
Linding, R., Jensen, L.J., Diella, F., Bork, P., Gibson, T.J. and Russell, R.B. (2003) Protein disorder prediction: implications for structural proteomics. Structure, 11, 1453-1459.
-
(2003)
Structure
, vol.11
, pp. 1453-1459
-
-
Linding, R.1
Jensen, L.J.2
Diella, F.3
Bork, P.4
Gibson, T.J.5
Russell, R.B.6
-
54
-
-
76849087968
-
PONDR-FIT: A meta-predictor of intrinsically disordered amino acids
-
Xue, B., Dunbrack, R.L., Williams, R.W., Dunker, A.K. and Uversky, V.N. (2010) PONDR-FIT: a meta-predictor of intrinsically disordered amino acids. BBA-Proteins Proteom., 1804, 996-1010.
-
(2010)
BBA-Proteins Proteom
, vol.1804
, pp. 996-1010
-
-
Xue, B.1
Dunbrack, R.L.2
Williams, R.W.3
Dunker, A.K.4
Uversky, V.N.5
-
55
-
-
44349150513
-
OnD-CRF: Predicting order and disorder in proteins conditional random fields
-
Wang, L. and Sauer, U.H. (2008) OnD-CRF: predicting order and disorder in proteins conditional random fields. Bioinformatics, 24, 1401-1402.
-
(2008)
Bioinformatics
, vol.24
, pp. 1401-1402
-
-
Wang, L.1
Sauer, U.H.2
-
56
-
-
70349996473
-
ANCHOR: Web server for predicting protein binding regions in disordered proteins
-
Dosztá nyi, Z., Mészá ros, B. and Simon, I. (2009) ANCHOR: web server for predicting protein binding regions in disordered proteins. Bioinformatics, 25, 2745-2746.
-
(2009)
Bioinformatics
, vol.25
, pp. 2745-2746
-
-
Dosztányi, Z.1
Mészáros, B.2
Simon, I.3
-
57
-
-
0032493894
-
The novel ATM-related protein TRRAP is an essential cofactor for the C-Mcy and E2F oncoproteins
-
McMahon, S.B., Van Buskirk, H.A., Dugan, K.A., Copeland, T.D. and Cole, M.D. (1998) The novel ATM-related protein TRRAP is an essential cofactor for the C-Mcy and E2F oncoproteins. Cell, 94, 363-374.
-
(1998)
Cell
, vol.94
, pp. 363-374
-
-
McMahon, S.B.1
Van Buskirk, H.A.2
Dugan, K.A.3
Copeland, T.D.4
Cole, M.D.5
-
58
-
-
27944448727
-
Dual regulation of C-Mcy by p300 via acetylation-dependent control of Mcy protein turnover and coactivation of Mcy-induced transcription
-
Faiola, F., Liu, X., Lo, S., Pan, S., Zhang, K., Lymar, E., Farina, A. and Martinez, E. (2005) Dual Regulation of C-Mcy by p300 via Acetylation-Dependent Control of Mcy Protein Turnover and Coactivation of Mcy-Induced Transcription. Mol. Cell. Biol., 25, 10220-10234.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 10220-10234
-
-
Faiola, F.1
Liu, X.2
Lo, S.3
Pan, S.4
Zhang, K.5
Lymar, E.6
Farina, A.7
Martinez, E.8
-
59
-
-
21344463545
-
Identification of a novel C-Mcy protein interactor, JPO(2), with transforming activity in medulloblastoma cells
-
Huang, A., Ho, C.S.W., Ponzielli, R., Barsyte-Lovejoy, D., Bouffet, E., Picard, D., Hawkins, C.E. and Penn, L.Z. (2005) Identification of a novel C-Mcy protein interactor, JPO(2), with transforming activity in medulloblastoma cells. Cancer Res., 65, 5607-5619.
-
(2005)
Cancer Res
, vol.65
, pp. 5607-5619
-
-
Huang, A.1
Ho, C.S.W.2
Ponzielli, R.3
Barsyte-Lovejoy, D.4
Bouffet, E.5
Picard, D.6
Hawkins, C.E.7
Penn, L.Z.8
-
60
-
-
34547652267
-
CFTR regulatory region interacts with nbd1 predominantly via multiple transient helices
-
Baker, J.M., Hudson, R.P., Kanelis, V., Choy, W.Y., Thibodeau, P.H., Thomas, P.J. and Forman-Kay, J.D. (2007) CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices. Nat. Struct. Mol. Biol., 14, 738-745.
-
(2007)
Nat. Struct. Mol. Biol
, vol.14
, pp. 738-745
-
-
Baker, J.M.1
Hudson, R.P.2
Kanelis, V.3
Choy, W.Y.4
Thibodeau, P.H.5
Thomas, P.J.6
Forman-Kay, J.D.7
-
61
-
-
78650995206
-
Structural signature of the MYPT1-1 interaction
-
Pinheiro, A.S., Marsh, J.A., Forman-Kay, J.D. and Peti, W. (2011) Structural signature of the MYPT1-1 interaction. J. Am. Chem. Soc., 133, 73-80.
-
(2011)
J. Am. Chem. Soc
, vol.133
, pp. 73-80
-
-
Pinheiro, A.S.1
Marsh, J.A.2
Forman-Kay, J.D.3
Peti, W.4
-
62
-
-
57749209868
-
Crystal structures of protein phosphatase-1 bound to nodularin-R and tautoMcyin: A novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors
-
Kelker, M.S., Page, R. and Peti, W. (2009) Crystal structures of protein phosphatase-1 bound to nodularin-R and tautoMcyin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors. J. Mol. Biol., 385, 11-21.
-
(2009)
J. Mol. Biol
, vol.385
, pp. 11-21
-
-
Kelker, M.S.1
Page, R.2
Peti, W.3
-
63
-
-
18244364614
-
Long-range interactions within a nonnative protein
-
Klein-Seetharaman, J., Oikawa, M., Grimshaw, S.B., Wirmer, J., Duchardt, E., Ueda, T., Imoto, T., Smith, L.J., Dobson, C.M. and Schwalbe, H. (2002) Long-range interactions within a nonnative protein. Science, 295, 1719-1722.
-
(2002)
Science
, vol.295
, pp. 1719-1722
-
-
Klein-Seetharaman, J.1
Oikawa, M.2
Grimshaw, S.B.3
Wirmer, J.4
Duchardt, E.5
Ueda, T.6
Imoto, T.7
Smith, L.J.8
Dobson, C.M.9
Schwalbe, H.10
-
65
-
-
0036192061
-
-
Oster, S.K., Ho, C.S.W., Soucie, E.L. and Penn, L.Z. (2002) Adv. Cancer Res., 84, 81-154.
-
(2002)
Adv. Cancer Res
, vol.84
, pp. 81-154
-
-
Oster, S.K.1
Ho, C.S.W.2
Soucie, E.L.3
Penn, L.Z.4
-
66
-
-
0033551388
-
New Mcy-interacting proteins: A second Mcy network emerges
-
Sakamuro, D. and Prendergast, G.C. (1999) New Mcy-interacting proteins: a second Mcy network emerges. Oncogene, 18, 2942-2954.
-
(1999)
Oncogene
, vol.18
, pp. 2942-2954
-
-
Sakamuro, D.1
Prendergast, G.C.2
-
67
-
-
33644749307
-
P53 transcriptional activation domain: A molecular chameleon?
-
Kaustov, L., Yi, G.S., Ayed, A., Bochkareva, E., Bochkarev, A. and Arrowsmith, C.H. (2006) p53 transcriptional activation domain: a molecular chameleon? Cell Cycle, 5, 489-494.
-
(2006)
Cell Cycle
, vol.5
, pp. 489-494
-
-
Kaustov, L.1
Yi, G.S.2
Ayed, A.3
Bochkareva, E.4
Bochkarev, A.5
Arrowsmith, C.H.6
-
68
-
-
0031303353
-
Solution conformation of an essential region of the p53 transactivation domain
-
Botuyan, M.V., Momand, J. and Chen, Y. (1997) Solution conformation of an essential region of the p53 transactivation domain. Fold. Des., 2, 331-342.
-
(1997)
Fold. Des
, vol.2
, pp. 331-342
-
-
Botuyan, M.V.1
Momand, J.2
Chen, Y.3
-
69
-
-
0034703040
-
Local structural elements in the mostly unstructured transcriptional activation domain of human p53
-
Lee, H., Mok, K.H., Muhandiram, R., Park, K.-H., Suk, J.-E., Kim, D.-H., Chang, J., Sung, Y.C., Choi, K.Y. and Han, K.-H. (2000) Local structural elements in the mostly unstructured transcriptional activation domain of human p53. J. Biol. Chem., 275, 29426-29432.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 29426-29432
-
-
Lee, H.1
Mok, K.H.2
Muhandiram, R.3
Park, K.-H.4
Suk, J.-E.5
Kim, D.-H.6
Chang, J.7
Sung, Y.C.8
Choi, K.Y.9
Han, K.-H.10
-
70
-
-
0030575937
-
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
-
Kussie, P.H., Gorina, S., Marechal, V., Elenbaas, B., Moreau, J., Levine, A.J. and Pavletich, N.P. (1996) Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science, 274, 948-953.
-
(1996)
Science
, vol.274
, pp. 948-953
-
-
Kussie, P.H.1
Gorina, S.2
Marechal, V.3
Elenbaas, B.4
Moreau, J.5
Levine, A.J.6
Pavletich, N.P.7
-
71
-
-
33745214419
-
Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53
-
Di Lello, P., Jenkins, L.M.M., Jones, T.N., Nguyen, B.D., Hara, T., Yamaguchi, H., Dikeakos, J.D., Appella, E., Legault, P. and Omichinski, J.G. (2006) Structure of the Tfb1/p53 complex: insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53. Molecular Cell, 22, 731-740.
-
(2006)
Molecular Cell
, vol.22
, pp. 731-740
-
-
Di Lello, P.1
Jenkins, L.M.M.2
Jones, T.N.3
Nguyen, B.D.4
Hara, T.5
Yamaguchi, H.6
Dikeakos, J.D.7
Appella, E.8
Legault, P.9
Omichinski, J.G.10
-
72
-
-
59649109756
-
Structural basis for p300 Taz2-p53 tad1 binding and modulation by phosphorylation
-
Feng, H., Jenkins, L.M.M., Durell, S.R., Hayashi, R., Mazur, S.J., Cherry, S., Tropea, J.E., Miller, M., Wlodawer, A., Appella, E. et al. (2009) Structural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylation. Structure, 17, 202-210.
-
(2009)
Structure
, vol.17
, pp. 202-210
-
-
Feng, H.1
Jenkins, L.M.M.2
Durell, S.R.3
Hayashi, R.4
Mazur, S.J.5
Cherry, S.6
Tropea, J.E.7
Miller, M.8
Wlodawer, A.9
Appella, E.10
-
73
-
-
27344449049
-
Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A
-
Bochkareva, E., Kaustov, L., Ayed, A., Yi, G.-S., Lu, Y., Pineda-Lucena, A., Liao, J.C.C., Okorokov, A.L., Milner, J., Arrowsmith, C.H. et al. (2005) Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A. Proc. Natl Acad. Sci. USA, 102, 15412-15417.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 15412-15417
-
-
Bochkareva, E.1
Kaustov, L.2
Ayed, A.3
Yi, G.-S.4
Lu, Y.5
Pineda-Lucena, A.6
Liao, J.C.C.7
Okorokov, A.L.8
Milner, J.9
Arrowsmith, C.H.10
-
74
-
-
78649284498
-
Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein
-
Lee, C.W., Martinez-Yamout, M.A., Dyson, H.J. and Wright, P.E. (2010) Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein. Biochemistry, 49, 9964-9971.
-
(2010)
Biochemistry
, vol.49
, pp. 9964-9971
-
-
Lee, C.W.1
Martinez-Yamout, M.A.2
Dyson, H.J.3
Wright, P.E.4
-
75
-
-
34548780897
-
Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX
-
Hu, B., Gilkes, D.M. and Chen, J. (2007) Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX. Cancer Res., 67, 8810-8817.
-
(2007)
Cancer Res
, vol.67
, pp. 8810-8817
-
-
Hu, B.1
Gilkes, D.M.2
Chen, J.3
-
76
-
-
63849271797
-
Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX
-
Pazgier, M., Liu, M., Zou, G., Yuan, W., Li, C., Li, C., Li, J., Monbo, J., Zella, D., Tarasov, S.G. et al. (2009) Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX. Proc. Natl Acad. Sci. USA, 106, 4665-4670.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 4665-4670
-
-
Pazgier, M.1
Liu, M.2
Zou, G.3
Yuan, W.4
Li, C.5
Li, C.6
Li, J.7
Monbo, J.8
Zella, D.9
Tarasov, S.G.10
-
77
-
-
77956280014
-
D-peptide inhibitors of the p53-MDM2 interaction for targeted molecular therapy of malignant neoplasms
-
Liu, M., Li, C., Pazgier, M., Li, C., Mao, Y., Lv, Y., Gu, B., Wei, G., Yuan, W., Zhan, C. et al. (2010) D-peptide inhibitors of the p53-MDM2 interaction for targeted molecular therapy of malignant neoplasms. Proc. Natl Acad. Sci. USA, 107, 14321-14326.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 14321-14326
-
-
Liu, M.1
Li, C.2
Pazgier, M.3
Li, C.4
Mao, Y.5
Lv, Y.6
Gu, B.7
Wei, G.8
Yuan, W.9
Zhan, C.10
-
78
-
-
0027275755
-
Point mutations in the C-Mcy transactivation domain are common in burkitt's lymphoma and mouse plasmacytomas
-
Bhatia, K., Huppi, K., Spangler, G., Siwarski, D., Iyer, R. and Magrath, I. (1993) Point mutations in the C-Mcy transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas. Nat Genet, 5, 56-61.
-
(1993)
Nat Genet
, vol.5
, pp. 56-61
-
-
Bhatia, K.1
Huppi, K.2
Spangler, G.3
Siwarski, D.4
Iyer, R.5
Magrath, I.6
-
79
-
-
56649112976
-
Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor
-
Mittag, T., Orlicky, S., Choy, W.Y., Tang, X., Lin, H., Sicheri, F., Kay, L.E., Tyers, M. and Forman-Kay, J.D. (2008) Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor. Proc. Natl Acad. Sci. USA, 105, 17772-17777.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 17772-17777
-
-
Mittag, T.1
Orlicky, S.2
Choy, W.Y.3
Tang, X.4
Lin, H.5
Sicheri, F.6
Kay, L.E.7
Tyers, M.8
Forman-Kay, J.D.9
-
80
-
-
34547462095
-
Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitiviyt
-
Borg, M., Mittag, T., Pawson, T., Tyers, M., Forman-Kay, J.D. and Chan, H.S. (2007) Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitiviyt. Proc. Natl Acad. Sci. USA, 104, 9650-9655.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 9650-9655
-
-
Borg, M.1
Mittag, T.2
Pawson, T.3
Tyers, M.4
Forman-Kay, J.D.5
Chan, H.S.6
-
81
-
-
0027220154
-
Tata-binding protein and the retinoblastoma gene-product bind to overlapping epitopes on C-Mcy and adenovirus E1A protein
-
Hateboer, G., Timmers, H.T.M., Rustgi, A.K., Billaud, M., Vantveer, L.J. and Bernards, R. (1993) TATA-binding protein and the retinoblastoma gene-product bind to overlapping epitopes on C-Mcy and adenovirus E1A protein. Proc. Natl Acad. Sci. USA, 90, 8489-8493.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 8489-8493
-
-
Hateboer, G.1
Timmers, H.T.M.2
Rustgi, A.K.3
Billaud, M.4
Vantveer, L.J.5
Bernards, R.6
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