Impaired in vivo mitochondrial krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy

Circulation: Cardiovascular Imaging

Volumn 7, Issue 6, 2014, Pages 895-904

  Dodd, Michael S ^a   Atherton, Helen J ^a   Carr, Carolyn A ^a   Stuckey, Daniel J ^b   West, James A ^c   Griffin, Julian L ^c   Radda, George K ^a   Clarke, Kieran ^a   Heather, Lisa C ^a   Tyler, Damian J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Citric acid cycle; Heart; Magnetic resonance spectroscopy; Metabolism; Myocardial infarction

Indexed keywords

ACETYL COENZYME A; ACETYLCARNITINE; CITRIC ACID; GLUTAMIC ACID; PYRUVATE DEHYDROGENASE; BIOLOGICAL MARKER; PYRUVATE DEHYDROGENASE COMPLEX;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CITRIC ACID CYCLE; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; FEMALE; HEART DISEASE; HEART FAILURE; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE FIBER MEMBRANE STEADY POTENTIAL; HEART MUSCLE INJURY; HEART MUSCLE REPERFUSION; HEART OUTPUT; HEART STROKE VOLUME; HEART VENTRICLE REMODELING; IN VITRO STUDY; IN VIVO STUDY; METABOLOMICS; MITOCHONDRIAL RESPIRATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SCANNER; NUCLEAR MAGNETIC RESONANCE SPECTROMETER; PRIORITY JOURNAL; RAT; ANIMAL; CARDIAC MUSCLE; CINE MAGNETIC RESONANCE IMAGING; DISEASE MODEL; HEART LEFT VENTRICLE FUNCTION; HEART MITOCHONDRION; METABOLISM; MYOCARDIAL INFARCTION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOPHYSIOLOGY; PREDICTIVE VALUE; PROCEDURES; TIME FACTOR; WISTAR RAT;

ACETYLCARNITINE; ANIMALS; BIOMARKERS; CITRIC ACID; CITRIC ACID CYCLE; DISEASE MODELS, ANIMAL; FEMALE; GLUTAMIC ACID; MAGNETIC RESONANCE IMAGING, CINE; MAGNETIC RESONANCE SPECTROSCOPY; METABOLOMICS; MITOCHONDRIA, HEART; MYOCARDIAL INFARCTION; MYOCARDIUM; PREDICTIVE VALUE OF TESTS; PYRUVATE DEHYDROGENASE COMPLEX; RATS, WISTAR; STROKE VOLUME; TIME FACTORS; VENTRICULAR FUNCTION, LEFT;

EID: 84961287921     PISSN: 19419651     EISSN: 19420080     Source Type: Journal    
DOI: 10.1161/CIRCIMAGING.114.001857     Document Type: Article

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