-
1
-
-
0014461121
-
Alpha-keto acid dehydrogenase complexes. X. Regulation of the activity of the pyruvate dehydrogenase complex from beef kidney mitochondria by phosphorylation and dephosphorylation
-
Linn TC, Pettit FH, Reed LJ. Alpha-keto acid dehydrogenase complexes. X. Regulation of the activity of the pyruvate dehydrogenase complex from beef kidney mitochondria by phosphorylation and dephosphorylation. Proc Natl Acad Sci U S A. 1969;62:234-241.
-
(1969)
Proc Natl Acad Sci U S A.
, vol.62
, pp. 234-241
-
-
Linn, T.C.1
Pettit, F.H.2
Reed, L.J.3
-
2
-
-
0018128881
-
Relative importance of pyruvate dehydrogenase interconversion and feed-back inhibition in the effect of fatty acids on pyruvate oxidation by rat heart mitochondria
-
Hansford RG, Cohen L. Relative importance of pyruvate dehydrogenase interconversion and feed-back inhibition in the effect of fatty acids on pyruvate oxidation by rat heart mitochondria. Arch Biochem Biophys. 1978;191:65-81. (Pubitemid 9050309)
-
(1978)
Archives of Biochemistry and Biophysics
, vol.191
, Issue.1
, pp. 65-81
-
-
Hansford, R.G.1
Cohen, L.2
-
3
-
-
0028148702
-
Epinephrine increases ATP production in hearts by preferentially increasing glucose metabolism
-
Collins-Nakai RL, Noseworthy D, Lopaschuk GD. Epinephrine increases ATP production in hearts by preferentially increasing glucose metabolism. Am J Physiol. 1994;267:H1862-H1871.
-
(1994)
Am J Physiol.
, vol.267
-
-
Collins-Nakai, R.L.1
Noseworthy, D.2
Lopaschuk, G.D.3
-
4
-
-
0018836411
-
Substrate, hormone, and temperature responses in males and females to a common breakfast
-
Owen OE, Mozzoli MA, Boden G, Patel MS, Reichard GA Jr, Trapp V, Shuman CR, Felig P. Substrate, hormone, and temperature responses in males and females to a common breakfast. Metabolism. 1980;29: 511-523. (Pubitemid 10123239)
-
(1980)
Metabolism: Clinical and Experimental
, vol.29
, Issue.6
, pp. 511-523
-
-
Owen, O.E.1
Mozzoli, M.A.2
Boden, G.3
-
5
-
-
0030053007
-
Is a high glycogen content beneficial or detrimental to the ischemic rat heart? A controversy resolved
-
Cross HR, Opie LH, Radda GK, Clarke K. Is a high glycogen content beneficial or detrimental to the ischemic rat heart? A controversy resolved. Circ Res. 1996;78:482-491.
-
(1996)
Circ Res.
, vol.78
, pp. 482-491
-
-
Cross, H.R.1
Opie, L.H.2
Radda, G.K.3
Clarke, K.4
-
6
-
-
0025821485
-
Myocardial triglyceride turnover and contribution to energy substrate utilization in isolated working rat hearts
-
Saddik M, Lopaschuk GD. Myocardial triglyceride turnover and contribution to energy substrate utilization in isolated working rat hearts. J Biolog Chem. 1991;266:8162-8170. (Pubitemid 21906491)
-
(1991)
Journal of Biological Chemistry
, vol.266
, Issue.13
, pp. 8162-8170
-
-
Saddik, M.1
Lopaschuk, G.D.2
-
7
-
-
0013878576
-
Effect of diabetes and starvation on myocardial triglyceride and free fatty acid utilization
-
Kreisberg RA. Effect of diabetes and starvation on myocardial triglyceride and free fatty acid utilization. Am J Physiol. 1966;210:379-384.
-
(1966)
Am J Physiol.
, vol.210
, pp. 379-384
-
-
Kreisberg, R.A.1
-
8
-
-
0013882021
-
Effect of epinephrine on myocardial triglyceride and free fatty acid utilization
-
Kreisberg RA. Effect of epinephrine on myocardial triglyceride and free fatty acid utilization. Am J Physiol.1966;210:385-389.
-
(1966)
Am J Physiol.
, vol.210
, pp. 385-389
-
-
Kreisberg, R.A.1
-
9
-
-
33947239659
-
The failing heart - An engine out of fuel
-
DOI 10.1056/NEJMra063052
-
Neubauer S. The failing heart-an engine out of fuel. N Engl J Med. 2007;356:1140-1151. (Pubitemid 46425598)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.11
, pp. 1140-1151
-
-
Neubauer, S.1
-
10
-
-
68849099655
-
Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy
-
Schroeder MA, Atherton HJ, Ball DR, Cole MA, Heather LC, Griffin JL, Clarke K, Radda GK, Tyler DJ. Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy. FASEB J. 2009;23:2529-2538.
-
(2009)
FASEB J.
, vol.23
, pp. 2529-2538
-
-
Schroeder, M.A.1
Atherton, H.J.2
Ball, D.R.3
Cole, M.A.4
Heather, L.C.5
Griffin, J.L.6
Clarke, K.7
Radda, G.K.8
Tyler, D.J.9
-
11
-
-
0042763165
-
Increase in signal-to-noise ratio of >10,000 times in liquid-state NMR
-
DOI 10.1073/pnas.1733835100
-
Ardenkjaer-Larsen JH, Fridlund B, Gram A, Hansson G, Hansson L, Lerche MH, Servin R, Thaning M, Golman K. Increase in signal-to-noise ratio of >10, 000 times in liquid-state NMR. Proc Natl Acad Sci U S A. 2003;100:10158-10163. (Pubitemid 37071849)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.18
, pp. 10158-10163
-
-
Ardenkjaer-Larsen, J.H.1
Fridlund, B.2
Gram, A.3
Hansson, G.4
Hansson, L.5
Lerche, M.H.6
Servin, R.7
Thaning, M.8
Golman, K.9
-
13
-
-
0032128015
-
Carnitine acetyltransferase is not a cytosolic enzyme in rat heart and therefore cannot function in the energy linked regulation of cardiac fatty acid oxidation
-
DOI 10.1006/jmcc.1998.0693
-
Abbas AS, Wu G, Schulz H. Carnitine acetyltransferase is not a cytosolic enzyme in rat heart and therefore cannot function in the energy-linked regulation of cardiac fatty acid oxidation. J Mol Cell Cardiol. 1998;30: 1305-1309. (Pubitemid 28345032)
-
(1998)
Journal of Molecular and Cellular Cardiology
, vol.30
, Issue.7
, pp. 1305-1309
-
-
Abbas, A.S.1
Wu, G.2
Schulz, H.3
-
14
-
-
0005857662
-
Reversible enzymatic acetylation of carnitine
-
Friedman S, Fraenkel G. Reversible enzymatic acetylation of carnitine. Arch Biochem Biophys. 1955;59:491-501.
-
(1955)
Arch Biochem Biophys.
, vol.59
, pp. 491-501
-
-
Friedman, S.1
Fraenkel, G.2
-
15
-
-
0000646490
-
Carnitine and derivatives in rat tissues
-
Pearson DJ, Tubbs PK. Carnitine and derivatives in rat tissues. Biochem J. 1967;105:953-963.
-
(1967)
Biochem J.
, vol.105
, pp. 953-963
-
-
Pearson, D.J.1
Tubbs, P.K.2
-
17
-
-
0001209759
-
Properties of partially purified carnitine acetyltransferase
-
Fritz IB, Schultz SK, Srere PA. Properties of partially purified carnitine acetyltransferase. J Biol Chem. 1963;238:2509-2517.
-
(1963)
J Biol Chem.
, vol.238
, pp. 2509-2517
-
-
Fritz, I.B.1
Schultz, S.K.2
Srere, P.A.3
-
18
-
-
0023856860
-
Quantitation of the effect of L-carnitine on the levels of acid-soluble short-chain acyl-CoA and CoASH in rat heart and liver mitochondria
-
Lysiak W, Lilly K, DiLisa F, Toth PP, Bieber LL. Quantitation of the effect of l-carnitine on the levels of acid-soluble short-chain acyl-CoA and coASH in rat heart and liver mitochondria. J Biol Chem. 1988;263: 1151-1156. (Pubitemid 18039914)
-
(1988)
Journal of Biological Chemistry
, vol.263
, Issue.3
, pp. 1151-1156
-
-
Lysiak, W.1
Lilly, K.2
DiLisa, F.3
Toth, P.P.4
Bieber, L.L.5
-
19
-
-
0000332050
-
Effects of carnitine on acetyl-CoA oxidation by heart muscle mitochondria
-
Fritz IB, Yue KT. Effects of carnitine on acetyl-CoA oxidation by heart muscle mitochondria. Am J Physiol. 1964;206:531-535.
-
(1964)
Am J Physiol.
, vol.206
, pp. 531-535
-
-
Fritz, I.B.1
Yue, K.T.2
-
20
-
-
0027453493
-
Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart
-
Saddik M, Gamble J, Witters LA, Lopaschuk GD. Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart. J Biol Chem. 1993;268:25836-25845. (Pubitemid 23358202)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.34
, pp. 25836-25845
-
-
Saddik, M.1
Gamble, J.2
Witters, L.A.3
Lopaschuk, G.D.4
-
21
-
-
0031884872
-
Carnitine deficiency-induced cardiomyopathy
-
DOI 10.1023/A:1006826620218
-
Paulson DJ. Carnitine deficiency-induced cardiomyopathy. Mol Cell Biochem. 1998;180:33-41. (Pubitemid 28118801)
-
(1998)
Molecular and Cellular Biochemistry
, vol.180
, Issue.1-2
, pp. 33-41
-
-
Paulson, D.J.1
-
22
-
-
0019949555
-
Carnitine deficiency presenting as familial cardiomyopathy: A treatable defect in carnitine transport
-
Waber LJ, Valle D, Neill C, DiMauro S, Shug A. Carnitine deficiency presenting as familial cardiomyopathy: a treatable defect in carnitine transport. J Pediatr. 1982;101:700-705.
-
(1982)
J Pediatr.
, vol.101
, pp. 700-705
-
-
Waber, L.J.1
Valle, D.2
Neill, C.3
Dimauro, S.4
Shug, A.5
-
24
-
-
0029124119
-
Propionyl l-carnitine improvement of hypertrophied heart function is accompanied by an increase in carbohydrate oxidation
-
Schonekess BO, Allard MF, Lopaschuk GD. Propionyl l-carnitine improvement of hypertrophied heart function is accompanied by an increase in carbohydrate oxidation. Circ Res. 1995;77:726-734.
-
(1995)
Circ Res.
, vol.77
, pp. 726-734
-
-
Schonekess, B.O.1
Allard, M.F.2
Lopaschuk, G.D.3
-
25
-
-
0022972428
-
Quantitation of the efflux of acylcarnitines from rat-heart, brain, and liver-mitochondria
-
Lysiak W, Toth PP, Suelter CH, Bieber LL. Quantitation of the efflux of acylcarnitines from rat-heart, brain, and liver-mitochondria. J Biol Chem. 1986;261:3698-3703.
-
(1986)
J Biol Chem.
, vol.261
, pp. 3698-3703
-
-
Lysiak, W.1
Toth, P.P.2
Suelter, C.H.3
Bieber, L.L.4
-
26
-
-
80053469087
-
Hyperpolarized magnetic resonance: A novel technique for the in vivo assessment of cardiovascular disease
-
Schroeder MA, Clarke K, Neubauer S, Tyler DJ. Hyperpolarized magnetic resonance: a novel technique for the in vivo assessment of cardiovascular disease. Circulation. 2011;124:1580-1594.
-
(2011)
Circulation.
, vol.124
, pp. 1580-1594
-
-
Schroeder, M.A.1
Clarke, K.2
Neubauer, S.3
Tyler, D.J.4
-
28
-
-
73649090022
-
Tissue-specific short chain fatty acid metabolism and slow metabolic recovery after ischemia from hyperpolarized NMR in vivo
-
Jensen PR, Peitersen T, Karlsson M, In 't Zandt R, Gisselsson A, Hansson G, Meier S, Lerche MH. Tissue-specific short chain fatty acid metabolism and slow metabolic recovery after ischemia from hyperpolarized NMR in vivo. J Biol Chem. 2009;284:36077-36082.
-
(2009)
J Biol Chem.
, vol.284
, pp. 36077-36082
-
-
Jensen, P.R.1
Peitersen, T.2
Karlsson, M.3
In'T Zandt, R.4
Gisselsson, A.5
Hansson, G.6
Meier, S.7
Lerche, M.H.8
-
29
-
-
50149105620
-
In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance
-
Schroeder M, Cochlin L, Heather L, Clarke K, Radda G, Tyler D. In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance. Proc Natl Acad Sci U S A. 2008; 105:12051-12056.
-
(2008)
Proc Natl Acad Sci U S A.
, vol.105
, pp. 12051-12056
-
-
Schroeder, M.1
Cochlin, L.2
Heather, L.3
Clarke, K.4
Radda, G.5
Tyler, D.6
-
30
-
-
59849111731
-
The application of hyperpolarized magnetic resonance in the study of cardiac metabolism
-
Tyler D, Schroeder M, Cochlin L, Clarke K, Radda G. The application of hyperpolarized magnetic resonance in the study of cardiac metabolism. Appl Magn Reson. 2008;34:523-531.
-
(2008)
Appl Magn Reson.
, vol.34
, pp. 523-531
-
-
Tyler, D.1
Schroeder, M.2
Cochlin, L.3
Clarke, K.4
Radda, G.5
-
31
-
-
0035033455
-
Java-based graphical user interface for MRUI, a software package for quantitation of in vivo/medical magnetic resonance spectroscopy signals
-
DOI 10.1016/S0010-4825(01)00006-3, PII S0010482501000063
-
Naressi A, Couturier C, Castang I, de Beer R, Graveron-Demilly D. Java-based graphical user interface for MRUI, a software package for quantitation of in vivo/medical magnetic resonance spectroscopy signals. Comput Biol Med. 2001;31:269-286. (Pubitemid 32378728)
-
(2001)
Computers in Biology and Medicine
, vol.31
, Issue.4
, pp. 269-286
-
-
Naressi, A.1
Couturier, C.2
Castang, I.3
De Beer, R.4
Graveron-Demilly, D.5
-
32
-
-
79958777022
-
Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: A combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study
-
Atherton HJ, Dodd MS, Heather LC, Schroeder MA, Griffin JL, Radda GK, Clarke K, Tyler DJ. Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: a combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study. Circulation. 2011;123:2552-2561.
-
(2011)
Circulation.
, vol.123
, pp. 2552-2561
-
-
Atherton, H.J.1
Dodd, M.S.2
Heather, L.C.3
Schroeder, M.A.4
Griffin, J.L.5
Radda, G.K.6
Clarke, K.7
Tyler, D.J.8
-
33
-
-
79951820751
-
Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS
-
Atherton HJ, Schroeder MA, Dodd MS, Heather LC, Carter EE, Cochlin LE, Nagel S, Sibson NR, Radda GK, Clarke K, Tyler DJ. Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS. NMR Biomed. 2011;24:201-208.
-
(2011)
NMR Biomed.
, vol.24
, pp. 201-208
-
-
Atherton, H.J.1
Schroeder, M.A.2
Dodd, M.S.3
Heather, L.C.4
Carter, E.E.5
Cochlin, L.E.6
Nagel, S.7
Sibson, N.R.8
Radda, G.K.9
Clarke, K.10
Tyler, D.J.11
-
34
-
-
72149088738
-
Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice
-
Zierhut ML, Yen YF, Chen AP, Bok R, Albers MJ, Zhang V, Tropp J, Park I, Vigneron DB, Kurhanewicz J, Hurd RE, Nelson SJ. Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice. J Magn Reson. 2010;202:85-92.
-
(2010)
J Magn Reson.
, vol.202
, pp. 85-92
-
-
Zierhut, M.L.1
Yen, Y.F.2
Chen, A.P.3
Bok, R.4
Albers, M.J.5
Zhang, V.6
Tropp, J.7
Park, I.8
Vigneron, D.B.9
Kurhanewicz, J.10
Hurd, R.E.11
Nelson, S.J.12
-
35
-
-
0001025498
-
The distribution of carnitine, acetylcarnitine, and carnitine acetyltransferase in rat tissues
-
Marquis NR, Fritz IB. The distribution of carnitine, acetylcarnitine, and carnitine acetyltransferase in rat tissues. J Biol Chem. 1965;240: 2193-2196.
-
(1965)
J Biol Chem.
, vol.240
, pp. 2193-2196
-
-
Marquis, N.R.1
Fritz, I.B.2
-
36
-
-
0026591869
-
Changes in carnitine and acetylcarnitine in human semen during cryopreservation
-
Grizard G, Lombard-Vignon N, Boucher D. Changes in carnitine and acetylcarnitine in human semen during cryopreservation. Hum Reprod. 1992;7:1245-1248.
-
(1992)
Hum Reprod.
, vol.7
, pp. 1245-1248
-
-
Grizard, G.1
Lombard-Vignon, N.2
Boucher, D.3
-
37
-
-
33645093211
-
Accelerated triacylglycerol turnover kinetics in hearts of diabetic rats include evidence for compartmented lipid storage
-
DOI 10.1152/ajpendo.00139.2005
-
O'Donnell JM, Zampino M, Alpert NM, Fasano MJ, Geenen DL, Lewandowski ED. Accelerated triacylglycerol turnover kinetics in hearts of diabetic rats include evidence for compartmented lipid storage. Am J Physiol. 2006;290:E448-E455. (Pubitemid 43671690)
-
(2006)
American Journal of Physiology - Endocrinology and Metabolism
, vol.290
, Issue.3
-
-
O'Donnell, J.M.1
Zampino, M.2
Alpert, N.M.3
Fasano, M.J.4
Geenen, D.L.5
Lewandowski, E.D.6
-
38
-
-
0029161732
-
Cardiac responses to induced lactate oxidation: NMR analysis of metabolic equilibria
-
Lewandowski ED, Damico LA, White LT, Yu X. Cardiac responses to induced lactate oxidation: NMR analysis of metabolic equilibria. Am J Physiol. 1995;269:H160-H168.
-
(1995)
Am J Physiol.
, vol.269
-
-
Lewandowski, E.D.1
Damico, L.A.2
White, L.T.3
Yu, X.4
-
39
-
-
12744259923
-
Regulation of pyruvate dehydrogenase activity and citric acid cycle intermediates during high cardiac power generation
-
Sharma N, Okere IC, Brunengraber DZ, McElfresh TA, King KL, Sterk JP, Huang H, Chandler MP, Stanley WC. Regulation of pyruvate dehydrogenase activity and citric acid cycle intermediates during high cardiac power generation. J Physiol. 2005;562:593-603.
-
(2005)
J Physiol.
, vol.562
, pp. 593-603
-
-
Sharma, N.1
Okere, I.C.2
Brunengraber, D.Z.3
McElfresh, T.A.4
King, K.L.5
Sterk, J.P.6
Huang, H.7
Chandler, M.P.8
Stanley, W.C.9
-
40
-
-
2542430285
-
Limited transfer of cytosolic NADH into mitochondria at high cardiac workload
-
DOI 10.1152/ajpheart.01113.2003
-
O'Donnell JM, Kudej RK, LaNoue KF, Vatner SF, Lewandowski ED. Limited transfer of cytosolic NADH into mitochondria at high cardiac workload. Am J Physiol Heart Circ Physiol. 2004;286:H2237-H2242. (Pubitemid 38685238)
-
(2004)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.286
, Issue.6
-
-
O'Donnell, J.M.1
Kudej, R.K.2
LaNoue, K.F.3
Vatner, S.F.4
Lewandowski, E.D.5
-
42
-
-
0027369711
-
Myocardial carnitine metabolism in congestive heart failure induced by incessant tachycardia
-
Pierpont ME, Foker JE, Pierpont GL. Myocardial carnitine metabolism in congestive heart failure induced by incessant tachycardia. Basic Res Cardiol. 1993;88:362-370. (Pubitemid 23301329)
-
(1993)
Basic Research in Cardiology
, vol.88
, Issue.4
, pp. 362-370
-
-
Pierpont, M.E.M.1
Foker, J.E.2
Pierpont, G.L.3
|