Anti-diabetic effect of 3-hydroxy-2-naphthoic acid, an endoplasmic reticulum stress-reducing chemical chaperone

European Journal of Pharmacology

Volumn 779, Issue , 2016, Pages 157-167

  Park, Sun Mi ^a   Choi, Jungsook ^a   Nam, Tae Gyu ^b   Ku, Jin Mo ^a   Jeong, Kwiwan ^a  

^a Gyeonggi Institute of Science and Technology Promotion   (South Korea)

^b Hanyang University   (South Korea)

Author keywords

Beta cell death; Chemical chaperone; Diabetes mellitus; Endoplasmic reticulum stress; Insulin resistance; Unfolded protein response

Indexed keywords

3 HYDROXY 2 NAPHTHOIC ACID; ANTIDIABETIC AGENT; CHAPERONE; GLUCOSE TRANSPORTER 4; I KAPPA B KINASE BETA; INSULIN RECEPTOR SUBSTRATE 1; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; 3-HYDROXY-2-NAPHTHOIC ACID; INSULIN; NAPHTHOL DERIVATIVE;

3T3 CELL LINE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; APOPTOSIS; ARTICLE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GLUCOSE TOLERANCE; HEK293 CELL LINE; HEPG2 CELL LINE; HUMAN; HUMAN CELL; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LIPOTOXICITY; MOUSE; NONHUMAN; OB/OB MOUSE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; ADIPOCYTE; ANIMAL; DRUG EFFECTS; METABOLISM; PATHOLOGY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ADIPOCYTES; ANIMALS; APOPTOSIS; ENDOPLASMIC RETICULUM STRESS; GLUCOSE TRANSPORTER TYPE 4; HEK293 CELLS; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; MICE; NAPHTHOLS; PALMITIC ACID; PPAR GAMMA; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

EID: 84961226980     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2016.03.023     Document Type: Article

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